Jeremy P Cheadle

Jeremy P Cheadle

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Jeremy P Cheadle

Jeremy P Cheadle

Publications by authors named "Jeremy P Cheadle"

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43Publications

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Comprehensive analysis of colorectal cancer-risk loci and survival outcome: A prognostic role for CDH1 variants.

Eur J Cancer 2019 Nov 14;124:56-63. Epub 2019 Nov 14.

Division of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.09.024DOI Listing
November 2019

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Nat Commun 2019 05 14;10(1):2154. Epub 2019 May 14.

Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://www.nature.com/articles/s41467-019-09775-w
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http://dx.doi.org/10.1038/s41467-019-09775-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517433PMC
May 2019

and Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer.

Clin Cancer Res 2017 Jun 4;23(11):2742-2749. Epub 2016 Nov 4.

Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1541DOI Listing
June 2017

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

Authors:
Timothy H T Cheng Deborah Thompson Jodie Painter Tracy O'Mara Maggie Gorman Lynn Martin Claire Palles Angela Jones Daniel D Buchanan Aung Ko Win John Hopper Mark Jenkins Noralane M Lindor Polly A Newcomb Steve Gallinger David Conti Fred Schumacher Graham Casey Graham G Giles Paul Pharoah Julian Peto Angela Cox Anthony Swerdlow Fergus Couch Julie M Cunningham Ellen L Goode Stacey J Winham Diether Lambrechts Peter Fasching Barbara Burwinkel Hermann Brenner Hiltrud Brauch Jenny Chang-Claude Helga B Salvesen Vessela Kristensen Hatef Darabi Jingmei Li Tao Liu Annika Lindblom Per Hall Magdalena Echeverry de Polanco Monica Sans Angel Carracedo Sergi Castellvi-Bel Augusto Rojas-Martinez Samuel Aguiar Jnr Manuel R Teixeira Alison M Dunning Joe Dennis Geoffrey Otton Tony Proietto Elizabeth Holliday John Attia Katie Ashton Rodney J Scott Mark McEvoy Sean C Dowdy Brooke L Fridley Henrica M J Werner Jone Trovik Tormund S Njolstad Emma Tham Miriam Mints Ingo Runnebaum Peter Hillemanns Thilo Dörk Frederic Amant Stefanie Schrauwen Alexander Hein Matthias W Beckmann Arif Ekici Kamila Czene Alfons Meindl Manjeet K Bolla Kyriaki Michailidou Jonathan P Tyrer Qin Wang Shahana Ahmed Catherine S Healey Mitul Shah Daniela Annibali Jeroen Depreeuw Nada A Al-Tassan Rebecca Harris Brian F Meyer Nicola Whiffin Fay J Hosking Ben Kinnersley Susan M Farrington Maria Timofeeva Albert Tenesa Harry Campbell Robert W Haile Shirley Hodgson Luis Carvajal-Carmona Jeremy P Cheadle Douglas Easton Malcolm Dunlop Richard Houlston Amanda Spurdle Ian Tomlinson

Sci Rep 2015 12 1;5:17369. Epub 2015 Dec 1.

Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/srep17369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664893PMC
December 2015

Response.

J Natl Cancer Inst 2014 Apr 26;106(5). Epub 2014 Apr 26.

Affiliations of authors: Institute of Cancer and Genetics (CGS, HW, RH, SI, JPC) and Institute of Psychological Medicine and Clinical Neurosciences (VM), School of Medicine, Cardiff University, Cardiff, UK; Gray Institute for Radiation Oncology and Biology, University of Oxford, Oxford, UK (TSM); MRC Clinical Trials Unit, London, UK (RK); Wellcome Trust Brenner Building, St James' University Hospital, University of Leeds, Leeds, UK (SR, PQ, MS); Institute of Human Genetics, University Hospital Bonn, Bonn, Germany (VS, PP); Leiden University Medical Center, Department of Clinical Genetics, Leiden, The Netherlands (FJH, JW).

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http://dx.doi.org/10.1093/jnci/dju087DOI Listing
April 2014

Exome resequencing identifies potential tumor-suppressor genes that predispose to colorectal cancer.

Hum Mutat 2013 Jul 20;34(7):1026-34. Epub 2013 May 20.

Institute of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, UK.

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http://dx.doi.org/10.1002/humu.22333DOI Listing
July 2013

Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis.

Hum Mol Genet 2009 Jun 25;18(12):2166-76. Epub 2009 Mar 25.

Institute of Medical Genetics, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.

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http://dx.doi.org/10.1093/hmg/ddp149DOI Listing
June 2009

Cognitive deficits in Tsc1+/- mice in the absence of cerebral lesions and seizures.

Ann Neurol 2007 Dec;62(6):648-55

Department of Neuroscience, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/ana.21317DOI Listing
December 2007

MUTYH-associated polyposis--from defect in base excision repair to clinical genetic testing.

DNA Repair (Amst) 2007 Mar 11;6(3):274-9. Epub 2006 Dec 11.

Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff CF14 4XN, UK.

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http://dx.doi.org/10.1016/j.dnarep.2006.11.001DOI Listing
March 2007

Rapid recognition of aberrant dHPLC elution profiles using the Transgenomic Navigator software.

Hum Mutat 2005 Aug;26(2):165

Institute of Medical Genetics, Cardiff University, Health Park, Cardiff, CF14 4XN, United Kingdom.

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http://dx.doi.org/10.1002/humu.9354DOI Listing
August 2005

Inherited variants in MYH are unlikely to contribute to the risk of lung carcinoma.

Hum Genet 2004 Jan 25;114(2):207-10. Epub 2003 Oct 25.

Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, Wales, UK.

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http://link.springer.com/10.1007/s00439-003-1033-2
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http://dx.doi.org/10.1007/s00439-003-1033-2DOI Listing
January 2004

Exposing the MYtH about base excision repair and human inherited disease.

Hum Mol Genet 2003 Oct 5;12 Spec No 2:R159-65. Epub 2003 Aug 5.

Institute of Medical Genetics, University of Wales College of Medicine, Cardiff, UK.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddg259DOI Listing
October 2003

Characterizing mutations in samples with low-level mosaicism by collection and analysis of DHPLC fractionated heteroduplexes.

Hum Mutat 2003 Feb;21(2):112-5

Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff, UK.

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http://doi.wiley.com/10.1002/humu.10159
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http://dx.doi.org/10.1002/humu.10159DOI Listing
February 2003

Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations.

Hum Mol Genet 2002 Nov;11(23):2961-7

Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff, CF14 4XN, UK.

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http://dx.doi.org/10.1093/hmg/11.23.2961DOI Listing
November 2002

Temperature modulation of DHPLC analysis for detection of coexisting constitutional and mosaic sequence variants in TSC2.

J Biochem Biophys Methods 2002 Apr;51(2):161-4

Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK.

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http://dx.doi.org/10.1016/s0165-022x(02)00011-8DOI Listing
April 2002

Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors.

Nat Genet 2002 Feb 30;30(2):227-32. Epub 2002 Jan 30.

Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff, CF14 4XN, UK.

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http://www.nature.com/articles/ng828
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http://dx.doi.org/10.1038/ng828DOI Listing
February 2002

Different combinations of biallelic APC mutation confer different growth advantages in colorectal tumours.

Cancer Res 2002 Jan;62(2):363-6

Institute of Medical Genetics, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, United Kingdom.

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January 2002