Publications by authors named "Jeremy M Boss"

90Publications

Selective DNA Demethylation Accompanies T Cell Homeostatic Proliferation and Gene Regulation in Lupus-Prone Mice.

Immunohorizons 2020 Oct 23;4(10):679-687. Epub 2020 Oct 23.

Vermont Center for Immunology and Infectious Diseases, Department of Medicine, University of Vermont Larner College of Medicine, Burlington, VT 05405; and

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October 2020

Antibody-secreting cell destiny emerges during the initial stages of B-cell activation.

Nat Commun 2020 08 10;11(1):3989. Epub 2020 Aug 10.

Department of Microbiology and Immunology and the Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, 30322, USA.

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August 2020

Murine gammaherpesvirus infection is skewed toward Igλ+ B cells expressing a specific heavy chain V-segment.

PLoS Pathog 2020 04 30;16(4):e1008438. Epub 2020 Apr 30.

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America.

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April 2020

Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8 T cells.

Nat Immunol 2020 03 17;21(3):309-320. Epub 2020 Jan 17.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.

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March 2020

PD-1 Expression during Acute Infection Is Repressed through an LSD1-Blimp-1 Axis.

J Immunol 2020 01 6;204(2):449-458. Epub 2019 Dec 6.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322; and

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January 2020

IgM, IgG, and IgA Influenza-Specific Plasma Cells Express Divergent Transcriptomes.

J Immunol 2019 10 9;203(8):2121-2129. Epub 2019 Sep 9.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322;

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October 2019

LSD1 Cooperates with Noncanonical NF-κB Signaling to Regulate Marginal Zone B Cell Development.

J Immunol 2019 10 6;203(7):1867-1881. Epub 2019 Sep 6.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322

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October 2019

The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation.

J Immunol 2018 11 19;201(9):2799-2811. Epub 2018 Sep 19.

Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322

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November 2018

Progressive Upregulation of Oxidative Metabolism Facilitates Plasmablast Differentiation to a T-Independent Antigen.

Cell Rep 2018 06;23(11):3152-3159

Department of Microbiology and Immunology and the Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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June 2018

B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.

Nat Commun 2018 05 15;9(1):1900. Epub 2018 May 15.

Department of Microbiology & Immunology, Emory University School of Medicine, 1510 Clifton Rd., Rm 3001, Atlanta, GA, 30322, USA.

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May 2018

Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs.

Nat Commun 2018 04 27;9(1):1698. Epub 2018 Apr 27.

Department of Microbiology and Immunology, Emory University, Atlanta, GA, 30322, USA.

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April 2018

LSD1 protects against hippocampal and cortical neurodegeneration.

Nat Commun 2017 10 9;8(1):805. Epub 2017 Oct 9.

Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, 30322, USA.

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October 2017

The molecular signature of murine T cell homeostatic proliferation reveals both inflammatory and immune inhibition patterns.

J Autoimmun 2017 Aug 24;82:47-61. Epub 2017 May 24.

Department of Medicine, The University of Vermont College of Medicine, Burlington, VT 05405-0068, USA.

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August 2017

Cutting Edge: Chromatin Accessibility Programs CD8 T Cell Memory.

J Immunol 2017 03 8;198(6):2238-2243. Epub 2017 Feb 8.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322; and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322

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March 2017

Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory.

J Immunol 2017 01 28;198(1):205-217. Epub 2016 Nov 28.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322; and

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January 2017

Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation.

Nat Immunol 2016 10 8;17(10):1216-1225. Epub 2016 Aug 8.

Department of Microbiology & Immunology Emory University School of Medicine Atlanta, GA, USA.

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October 2016

ZBTB32 Restricts the Duration of Memory B Cell Recall Responses.

J Immunol 2016 08 29;197(4):1159-68. Epub 2016 Jun 29.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110;

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August 2016

ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in naïve SLE B cells.

Sci Rep 2016 06 1;6:27030. Epub 2016 Jun 1.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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June 2016

Genetic and Epigenetic Regulation of PD-1 Expression.

J Immunol 2016 Mar;196(6):2431-7

Department of Microbiology and Immunology and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322

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March 2016

NF-κB regulates PD-1 expression in macrophages.

J Immunol 2015 May 25;194(9):4545-54. Epub 2015 Mar 25.

Department of Microbiology and Immunology and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322; and

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May 2015

Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment.

Nucleic Acids Res 2015 Mar 9;43(6):3128-42. Epub 2015 Mar 9.

Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA

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March 2015

B cell differentiation is associated with reprogramming the CCCTC binding factor-dependent chromatin architecture of the murine MHC class II locus.

J Immunol 2014 Apr 14;192(8):3925-35. Epub 2014 Mar 14.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322.

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April 2014

Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection.

J Exp Med 2014 Mar 3;211(3):515-27. Epub 2014 Mar 3.

Department of Microbiology and Immunology and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322.

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March 2014

The role of innate and adaptive immunity in Parkinson's disease.

J Parkinsons Dis 2013 ;3(4):493-514

Department of Physiology, Emory University School of Medicine, Atlanta, GA, USA.

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August 2014

Global DNA methylation remodeling accompanies CD8 T cell effector function.

J Immunol 2013 Sep 16;191(6):3419-29. Epub 2013 Aug 16.

Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA.

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September 2013

Multiple histone methyl and acetyltransferase complex components bind the HLA-DRA gene.

PLoS One 2012 31;7(5):e37554. Epub 2012 May 31.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America.

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October 2012

Cohesin regulates MHC class II genes through interactions with MHC class II insulators.

J Immunol 2011 Oct 12;187(8):4236-44. Epub 2011 Sep 12.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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October 2011

Regulation of major histocompatibility complex class II genes.

Curr Opin Immunol 2011 Feb 21;23(1):81-7. Epub 2010 Oct 21.

Department of Microbiology & Immunology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, United States.

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February 2011

Solution structure of the heterotrimeric complex between the interaction domains of RFX5 and RFXAP from the RFX gene regulatory complex.

J Mol Biol 2010 Oct 21;403(1):40-51. Epub 2010 Aug 21.

Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA. Electronic address:

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October 2010

CTCF controls expression and chromatin architecture of the human major histocompatibility complex class II locus.

Mol Cell Biol 2010 Sep 28;30(17):4211-23. Epub 2010 Jun 28.

Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA.

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September 2010

PU.1 binds to a distal regulatory element that is necessary for B cell-specific expression of CIITA.

J Immunol 2010 May 2;184(9):5018-28. Epub 2010 Apr 2.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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May 2010

Formation of the RFX gene regulatory complex induces folding of the interaction domain of RFXAP.

Proteins 2009 Aug;76(3):655-64

Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02141, USA.

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August 2009

Yin yang 1 regulates the expression of snail through a distal enhancer.

Mol Cancer Res 2009 Feb 10;7(2):221-9. Epub 2009 Feb 10.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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February 2009

Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation.

Photochem Photobiol 2009 May-Jun;85(3):652-62. Epub 2008 Dec 8.

Department of Dermatology, Emory University School of Medicine, Atlanta, GA, USA.

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June 2009

NFATc1 regulates PD-1 expression upon T cell activation.

J Immunol 2008 Oct;181(7):4832-9

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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October 2008

Assembly of the RFX complex on the MHCII promoter: role of RFXAP and RFXB in relieving autoinhibition of RFX5.

Biochim Biophys Acta 2008 Dec 6;1779(12):797-804. Epub 2008 Aug 6.

Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.

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December 2008

Tomorrow's JI Today.

Authors:
Jeremy M Boss

J Immunol 2008 Jul;181(1):1-2

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July 2008

The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions.

J Exp Med 2008 Apr 17;205(4):785-98. Epub 2008 Mar 17.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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April 2008

Mentoring and networking: how to make it work.

Nat Immunol 2008 Jan;9(1):3-5

Trudeau Institute, Saranac Lake, New York 12983, USA.

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January 2008

A 3' enhancer controls snail expression in melanoma cells.

Cancer Res 2007 Jul;67(13):6113-20

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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July 2007

Controlling the Ir genes.

Authors:
Jeremy M Boss

J Immunol 2007 Jun;178(11):6675-6

Department of Microbiology and Immunology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA.

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June 2007

Characterization of the RFX complex and the RFX5(L66A) mutant: implications for the regulation of MHC class II gene expression.

Biochemistry 2007 Feb 20;46(6):1597-611. Epub 2007 Jan 20.

Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250, USA.

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February 2007

Epigenetic regulation during B cell differentiation controls CIITA promoter accessibility.

J Immunol 2006 Sep;177(6):3865-73

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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September 2006

Lab management: insights for the new investigator.

Nat Immunol 2006 Sep;7(9):895-7

Trudeau Institute, Saranac Lake, New York 12983, USA.

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September 2006

C/EBPbeta regulates TNF induced MnSOD expression and protection against apoptosis.

Apoptosis 2006 Oct;11(10):1837-49

Department of Microbiology and Immunology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA.

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October 2006

Mechanism of action of a distal NF-kappaB-dependent enhancer.

Mol Cell Biol 2006 Aug;26(15):5759-70

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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August 2006

CREB and phospho-CREB interact with RFX5 and CIITA to regulate MHC class II genes.

Mol Immunol 2007 Feb 24;44(5):837-47. Epub 2006 May 24.

Department of Microbiology and Immunology, Emory University School of Medicine, 1510 Clifton Rd., Atlanta, GA 30322, USA.

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February 2007

The human major histocompatibility complex class II HLA-DRB1 and HLA-DQA1 genes are separated by a CTCF-binding enhancer-blocking element.

J Biol Chem 2006 Jul 4;281(27):18435-43. Epub 2006 May 4.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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July 2006

Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells.

J Immunol 2006 Apr;176(7):4083-93

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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April 2006

A cytokine promoter/yellow fluorescent protein reporter transgene serves as an early activation marker of lymphocyte subsets.

Cell Immunol 2005 Oct 10;237(2):131-40. Epub 2006 Jan 10.

Department of Microbiology and Immunology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322, USA.

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October 2005

Conserved residues of the bare lymphocyte syndrome transcription factor RFXAP determine coordinate MHC class II expression.

Mol Immunol 2006 Feb 12;43(5):395-409. Epub 2005 Apr 12.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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February 2006

A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene.

J Immunol 2005 Dec;175(11):7407-18

Influenza Branch, Division of Viral and Rickettssial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

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December 2005

Activation of a methylated promoter mediated by a sequence-specific DNA-binding protein, RFX.

J Biol Chem 2005 Nov 15;280(47):38914-22. Epub 2005 Sep 15.

Department of Biochemistry and Molecular Biology, College of Medicine, University of South Florida, Tampa, Florida 33612, USA.

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November 2005

X box-like sequences in the MHC class II region maintain regulatory function.

J Immunol 2005 Jul;175(2):1030-40

Department of Microbiology and Immunology, Emory University School of Medicine, 1600 Clifton Road, Atlanta, GA 30322, USA.

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July 2005

Evolutionary conservation and characterization of the bare lymphocyte syndrome transcription factor RFX-B and its paralogue ANKRA2.

Immunogenetics 2005 Feb 18;56(11):788-97. Epub 2005 Jan 18.

Department of Microbiology and Immunology, Emory University School of Medicine, 1510 Clifton Rd., Atlanta, GA 30322, USA.

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February 2005

MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation.

Cell 2004 Oct;119(1):75-86

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

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October 2004

DNA methylation and expression of major histocompatibility complex class I and class II transactivator genes in human developmental tumor cells and in T cell malignancies.

Clin Immunol 2003 Oct;109(1):46-52

Division of Molecular Biology, Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

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October 2003

Regulation of the class II MHC pathway in primary human monocytes by granulocyte-macrophage colony-stimulating factor.

J Immunol 2003 Sep;171(5):2374-83

Department of Pediatrics, School of Medicine, Stanford University, CCSR Room 2120, 269 Campus Drive, Stanford, CA 94305, USA.

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September 2003

Communication between NF-kappa B and Sp1 controls histone acetylation within the proximal promoter of the monocyte chemoattractant protein 1 gene.

J Immunol 2003 Apr;170(8):4139-47

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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April 2003

Role of the intronic enhancer in tumor necrosis factor-mediated induction of manganous superoxide dismutase.

J Biol Chem 2003 Jun 8;278(26):23570-8. Epub 2003 Apr 8.

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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June 2003

The adenovirus e3 promoter is sensitive to activation signals in human T cells.

J Virol 2003 Jan;77(2):1112-9

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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January 2003

Transcriptional regulation of the MHC class II antigen presentation pathway.

Curr Opin Immunol 2003 Feb;15(1):105-11

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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February 2003

Modulation of gene expression by the MHC class II transactivator.

J Immunol 2002 Nov;169(9):5078-88

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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November 2002

CD94/NKG2 expression does not inhibit cytotoxic function of lymphocytic choriomeningitis virus-specific CD8+ T cells.

J Immunol 2002 Jul;169(2):693-701

Emory Vaccine Research Center and Department of Microbiology and Immunology, Emory University, Atlanta, GA 30329, USA.

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July 2002

Kinetics of a gamma interferon response: expression and assembly of CIITA promoter IV and inhibition by methylation.

Mol Cell Biol 2002 Jul;22(13):4781-91

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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July 2002

Class II transactivator is required for maximal expression of HLA-DOB in B cells.

J Immunol 2002 Feb;168(4):1780-6

Department of Microbiology, Emory University School of Medicine, Atlanta, GA 30322, USA.

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February 2002