Jeremy Chojnacki

Jeremy Chojnacki

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Jeremy Chojnacki

Jeremy Chojnacki

Publications by authors named "Jeremy Chojnacki"

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14Publications

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NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer's Disease.

Mol Neurobiol 2018 03 2;55(3):1977-1987. Epub 2017 Mar 2.

Department of Pathology, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1007/s12035-017-0467-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585057PMC
March 2018

Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia-reperfusion in the mouse.

Int J Cardiol 2016 Apr 4;209:215-20. Epub 2016 Feb 4.

VCU Pauley Heart Center, Virginia Commonwealth University, United States; Johnson Research Center for Critical Care, Virginia Commonwealth University, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.02.043DOI Listing
April 2016

Mechanistic Insight of Bivalent Compound 21MO as Potential Neuroprotectant for Alzheimer's Disease.

Molecules 2016 Mar 25;21(4):412. Epub 2016 Mar 25.

Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA 23298, USA.

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http://dx.doi.org/10.3390/molecules21040412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831581PMC
March 2016

Bivalent ligands incorporating curcumin and diosgenin as multifunctional compounds against Alzheimer's disease.

Bioorg Med Chem 2015 Nov 24;23(22):7324-31. Epub 2015 Oct 24.

School of Pharmacy-Department of Medicinal Chemistry, Virginia Commonwealth University, Biotech I, Suite 205, 800 E. Leigh St., PO Box 980540, Richmond, VA 23298, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.10.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641451PMC
November 2015

Pharmacologic Inhibition of the NLRP3 Inflammasome Preserves Cardiac Function After Ischemic and Nonischemic Injury in the Mouse.

J Cardiovasc Pharmacol 2015 Jul;66(1):1-8

*VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, VA; †Victoria Johnson Research Laboratories, Richmond, VA; ‡Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; Departments of §Medicinal Chemistry; ‖Pharmacotherapy and Outcome Studies, and ¶Pharmaceutics Virginia Commonwealth University, Richmond, VA.

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http://dx.doi.org/10.1097/FJC.0000000000000247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500673PMC
July 2015

Discovery of 5-(4-hydroxyphenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide as a neuroprotectant for Alzheimer's disease by hybridization of curcumin and melatonin.

ACS Chem Neurosci 2014 Aug 22;5(8):690-9. Epub 2014 May 22.

Department of Medicinal Chemistry, ‡Department of Internal Medicine, §Department of Physics, and ∥Department of Pharmaceutics, Virginia Commonwealth University , Richmond, Virginia 23298, United States.

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http://dx.doi.org/10.1021/cn500081sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140595PMC
August 2014

Design and biological characterization of hybrid compounds of curcumin and thalidomide for multiple myeloma.

Org Biomol Chem 2013 Aug 20;11(29):4757-63. Epub 2013 Jun 20.

Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia, USA.

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http://dx.doi.org/10.1039/c3ob40595hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089070PMC
August 2013

BF·OEt-Promoted Concise Synthesis of Difluoroboron-Derivatized Curcumins from Aldehydes and 2,4-Pentanedione.

Tetrahedron Lett 2013 Apr 13;54(16):2070-2073. Epub 2013 Feb 13.

Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia 23298.

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http://dx.doi.org/10.1016/j.tetlet.2013.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607379PMC
April 2013

Bivalent ligand containing curcumin and cholesterol as fluorescence probe for Aβ plaques in Alzheimer's disease.

ACS Chem Neurosci 2012 Feb 11;3(2):141-146. Epub 2011 Dec 11.

Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia, USA.

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http://dx.doi.org/10.1021/cn200122jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367438PMC
February 2012