Jeremy Chien

Jeremy Chien

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Jeremy Chien

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MutEx: a multifaceted gateway for exploring integrative pan-cancer genomic data.

Brief Bioinform 2019 Oct 7. Epub 2019 Oct 7.

Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM, USA, 87109.

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http://dx.doi.org/10.1093/bib/bbz084DOI Listing
October 2019

Coiled-Coil and C2 Domain-Containing Protein 1A (CC2D1A) Promotes Chemotherapy Resistance in Ovarian Cancer.

Front Oncol 2019 1;9:986. Epub 2019 Oct 1.

Division of Experimental Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN, United States.

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http://dx.doi.org/10.3389/fonc.2019.00986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779793PMC
October 2019

Genome-scale CRISPR knockout screen identifies as a modifier of PARP inhibitor sensitivity.

Commun Biol 2019 9;2:335. Epub 2019 Sep 9.

3Department of Biochemistry and Molecular Medicine, University of California, Davis, Sacramento, CA 95816 USA.

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http://dx.doi.org/10.1038/s42003-019-0580-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733792PMC
September 2019

Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors.

Sci Rep 2019 Jul 29;9(1):11002. Epub 2019 Jul 29.

Department of Biochemistry and Molecular Medicine, University of California, Davis. 2700 Stockton Blvd. Sacramento, 95817, California, USA.

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http://dx.doi.org/10.1038/s41598-019-47085-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662852PMC
July 2019

Emerging Cancer Therapeutic Targets in Protein Homeostasis.

AAPS J 2018 08 27;20(6):94. Epub 2018 Aug 27.

Division of Molecular Medicine, Department of Internal Medicine, University of New Mexico Health Sciences Center, 915 Camino de Salud NE, Albuquerque, NM, 87131, USA.

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http://dx.doi.org/10.1208/s12248-018-0254-1DOI Listing
August 2018

Olaparib-induced Adaptive Response Is Disrupted by FOXM1 Targeting that Enhances Sensitivity to PARP Inhibition.

Mol Cancer Res 2018 06 15;16(6):961-973. Epub 2018 Mar 15.

Department of Internal Medicine, University of New Mexico Comprehensive Cancer Center, University of New Mexico School of Medicine, Albuquerque, New Mexico.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
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http://dx.doi.org/10.1158/1541-7786.MCR-17-0607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705145PMC
June 2018

VaDiR: an integrated approach to Variant Detection in RNA.

Gigascience 2018 02;7(2)

Department of Internal Medicine, University of New Mexico Health Sciences Center, 2325 Camino de Salud NE, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1093/gigascience/gix122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827345PMC
February 2018

Complete Transcriptome RNA-Seq.

Methods Mol Biol 2017 ;1513:141-162

Medical Sciences Program, Indiana University School of Medicine, 1001 East 3rd Street, Bloomington, IN, 47405, USA.

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http://dx.doi.org/10.1007/978-1-4939-6539-7_10DOI Listing
January 2018

Co-selected mutations in VCP: a novel mechanism of resistance to VCP inhibitors.

Cell Death Dis 2018 01 18;9(2):35. Epub 2018 Jan 18.

Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, 66160, USA.

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http://dx.doi.org/10.1038/s41419-017-0049-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833740PMC
January 2018

Cisplatin and Pemetrexed Activate AXL and AXL Inhibitor BGB324 Enhances Mesothelioma Cell Death from Chemotherapy.

Front Pharmacol 2017 11;8:970. Epub 2018 Jan 11.

Division of Molecular Medicine, Department of Internal Medicine, UNMHSC School of Medicine, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, United States.

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http://dx.doi.org/10.3389/fphar.2017.00970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768913PMC
January 2018

Specific mutations in the D1-D2 linker region of VCP/p97 enhance ATPase activity and confer resistance to VCP inhibitors.

Cell Death Discov 2017 6;3:17065. Epub 2017 Nov 6.

Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, MO 66160, USA.

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http://www.nature.com/articles/cddiscovery201765
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http://dx.doi.org/10.1038/cddiscovery.2017.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672561PMC
November 2017

Network-based machine learning and graph theory algorithms for precision oncology.

NPJ Precis Oncol 2017 8;1(1):25. Epub 2017 Aug 8.

1Department of Computer Science and Engineering, University of Minnesota Twin Cities, Minneapolis, MN USA.

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http://dx.doi.org/10.1038/s41698-017-0029-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871915PMC
August 2017

digit-a tool for detection and identification of genomic interchromosomal translocations.

Nucleic Acids Res 2017 May;45(9):e72

Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA.

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http://dx.doi.org/10.1093/nar/gkx010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435966PMC
May 2017

VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal.

Mol Oncol 2016 12 28;10(10):1559-1574. Epub 2016 Sep 28.

Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2016.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423134PMC
December 2016

Regulation of chemo-sensitivity in ovarian cancer via a stroma dependent glutathione pathway.

Transl Cancer Res 2016 Sep;5(Suppl 3):S514-S519

Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS, USA.

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http://tcr.amegroups.com/article/view/9473/8403
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http://dx.doi.org/10.21037/tcr.2016.09.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287752PMC
September 2016

Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors.

Mol Oncol 2016 08 17;10(7):1099-117. Epub 2016 May 17.

Division of Basic Biomedical Sciences, Sanford School of Medicine of The University of South Dakota, Vermillion, SD 57069, USA; Department of Pathology, Faculty of Medicine, McGill University, Montreal, QC H3A 2B4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2016.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240778PMC
August 2016

Network-Based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis.

PLoS Comput Biol 2015 Dec 23;11(12):e1004465. Epub 2015 Dec 23.

Department of Computer Science and Engineering, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689380PMC
December 2015

Molecular determinants of chemotherapy resistance in ovarian cancer.

Pharmacogenomics 2015 Nov 10;16(16):1763-7. Epub 2015 Nov 10.

Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA.

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http://dx.doi.org/10.2217/pgs.15.130DOI Listing
November 2015

Neonatal Progesterone Programs Adult Uterine Responses to Progesterone and Susceptibility to Uterine Dysfunction.

Endocrinology 2015 Oct 23;156(10):3791-803. Epub 2015 Jul 23.

Institute for Reproductive Health and Regenerative Medicine, Departments of Pathology and Laboratory Medicine (P.D., M.A.K.R., K.K., D.C., M.J.S.), Cancer Biology (J.C.), and Anatomy and Cell Biology (K.F.R.), University of Kansas Medical Center, Kansas City, Kansas 66160.

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http://dx.doi.org/10.1210/en.2015-1397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588825PMC
October 2015

Robust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples.

Sci Rep 2015 Jul 23;5:12335. Epub 2015 Jul 23.

Department of Cancer Biology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas, 66160 Kansas City, USA.

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http://dx.doi.org/10.1038/srep12335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511951PMC
July 2015

Challenges and opportunities for next-generation sequencing in companion diagnostics.

Expert Rev Mol Diagn 2015 Feb 24;15(2):193-209. Epub 2014 Sep 24.

Illumina, Inc. 5200 Illumina Way, San Diego, CA 92122, USA.

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http://www.tandfonline.com/doi/full/10.1586/14737159.2015.96
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http://dx.doi.org/10.1586/14737159.2015.961916DOI Listing
February 2015

Tumor hypomethylation at 6p21.3 associates with longer time to recurrence of high-grade serous epithelial ovarian cancer.

Cancer Res 2014 Jun 11;74(11):3084-91. Epub 2014 Apr 11.

Authors' Affiliations: Departments of Health Sciences Research, Medical Oncology, Obstetrics and Gynecology, and Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles; Department of Research, Illumina, San Diego, California; Departments of Cancer Biology and Biostatistics, University of Kansas Medical Center, Kansas City, Kansas; and Vaccine and Gene Therapy Institute of Florida, Port St. Lucie, Florida

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054691PMC
June 2014

Assessment of resistance to anoikis in ovarian cancer.

Methods Mol Biol 2013 ;1049:347-54

Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.1007/978-1-62703-547-7_26DOI Listing
March 2014

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

Cancer Res 2013 Dec 23;73(24):7222-31. Epub 2013 Oct 23.

Authors' Affiliations: Biochemistry, Molecular Biology and Biophysics Department; Masonic Cancer Center, University of Minnesota, Minneapolis; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research; Medical Genome Facility and Department of Laboratory Medicine and Pathology; Department of Laboratory Medicine and Pathology; Division of Medical Oncology, Department of Oncology; Division of Epidemiology, Department of Health Sciences Research; Division of Oncology Research, Department of Oncology; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic; Women's Cancer Program, Mayo Clinic Cancer Center, Rochester, Minnesota; Department of Cancer Biology, University of Kansas, Kansas City, Kansas; Department of Obstetrics & Gynecology, University of Washington School of Medicine, Seattle, Washington; and Illumina Cambridge Ltd, Chesterford Research Park, Little Chesterford, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867573PMC
December 2013

Network-based survival analysis reveals subnetwork signatures for predicting outcomes of ovarian cancer treatment.

PLoS Comput Biol 2013 21;9(3):e1002975. Epub 2013 Mar 21.

Department of Computer Science and Engineering, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1002975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605061PMC
November 2013

Platinum-sensitive recurrence in ovarian cancer: the role of tumor microenvironment.

Front Oncol 2013 Sep 24;3:251. Epub 2013 Sep 24.

Department of Cancer Biology, University of Kansas Medical Center , Kansas City, KS , USA.

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http://dx.doi.org/10.3389/fonc.2013.00251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781360PMC
September 2013

Metformin intake is associated with better survival in ovarian cancer: a case-control study.

Cancer 2013 Feb 3;119(3):555-62. Epub 2012 Dec 3.

Department of Gynecologic Surgery, Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.1002/cncr.27706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553259PMC
February 2013

Role of heparan sulfatases in ovarian and breast cancer.

Am J Cancer Res 2013 18;3(1):34-45. Epub 2013 Jan 18.

Department of Experimental Pathology, Mayo Clinic College of Medicine Rochester, MN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555198PMC
January 2013

HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation.

Int J Cancer 2012 Mar 25;130(5):1029-35. Epub 2011 Apr 25.

Department of Laboratory Medicine and Experimental Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.1002/ijc.26044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206182PMC
March 2012

FusionHunter: identifying fusion transcripts in cancer using paired-end RNA-seq.

Bioinformatics 2011 Jun 5;27(12):1708-10. Epub 2011 May 5.

Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1093/bioinformatics/btr265DOI Listing
June 2011

HSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cells.

Cancer Res 2011 Mar 25;71(6):2152-61. Epub 2011 Jan 25.

Department of Experimental Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059381PMC
March 2011

Comparison of gene expression patterns between avian and human ovarian cancers.

Gynecol Oncol 2011 Feb 19;120(2):256-64. Epub 2010 Nov 19.

Gynecologic Oncology, Department of Women's Oncology, Moffitt Cancer and Research Center, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1016/j.ygyno.2010.10.030DOI Listing
February 2011

Expression and functional significance of HtrA1 loss in endometrial cancer.

Clin Cancer Res 2011 Feb 23;17(3):427-36. Epub 2010 Nov 23.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Wake Forest Medical Center, Salem, North Carolina, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-3069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057564PMC
February 2011

WT1 as a substrate of HtrA2: a potential pathway for therapeutic targeting by HtrA proteases.

Authors:
Jeremy Chien

Future Oncol 2010 Aug;6(8):1233-5

Mayo Clinic, Division of Experimental Pathology, Rochester, MN 55905, USA.

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https://www.futuremedicine.com/doi/10.2217/fon.10.84
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http://dx.doi.org/10.2217/fon.10.84DOI Listing
August 2010

High temperature requirement A3 (HtrA3) promotes etoposide- and cisplatin-induced cytotoxicity in lung cancer cell lines.

J Biol Chem 2010 Apr 12;285(16):12011-27. Epub 2010 Feb 12.

Department of Experimental Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.097790
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http://dx.doi.org/10.1074/jbc.M109.097790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852939PMC
April 2010

Downregulation of HtrA1 promotes resistance to anoikis and peritoneal dissemination of ovarian cancer cells.

Cancer Res 2010 Apr 13;70(8):3109-18. Epub 2010 Apr 13.

Department of Laboratory Medicine and Experimental Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-09-3557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579484PMC
April 2010

Serine protease HtrA1 associates with microtubules and inhibits cell migration.

Mol Cell Biol 2009 Aug 26;29(15):4177-87. Epub 2009 May 26.

Experimental Pathology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1128/MCB.00035-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715801PMC
August 2009

Analysis of gene expression in stage I serous tumors identifies critical pathways altered in ovarian cancer.

Gynecol Oncol 2009 Jul 1;114(1):3-11. Epub 2009 May 1.

Division of Experimental Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1016/j.ygyno.2009.04.002DOI Listing
July 2009

HtrA serine proteases as potential therapeutic targets in cancer.

Curr Cancer Drug Targets 2009 Jun;9(4):451-68

Department Biochemistry, Sect. Pathology, Via L. Armanni, 5, 80138 Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905973PMC
http://dx.doi.org/10.2174/156800909788486704DOI Listing
June 2009

Identification of tubulins as substrates of serine protease HtrA1 by mixture-based oriented peptide library screening.

J Cell Biochem 2009 May;107(2):253-63

Department of Experimental Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1002/jcb.22121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2983094PMC
May 2009

Elevated expression of serine protease HtrA1 in preeclampsia and its role in trophoblast cell migration and invasion.

Am J Obstet Gynecol 2008 Nov 29;199(5):557.e1-10. Epub 2008 Jul 29.

Department of Obstetrics, The Ohio State University Medical Center, Columbus, OH, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000293780800498
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http://dx.doi.org/10.1016/j.ajog.2008.04.046DOI Listing
November 2008

Molecular pathogenesis and therapeutic targets in epithelial ovarian cancer.

J Cell Biochem 2007 Dec;102(5):1117-29

Department of Experimental Pathology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1002/jcb.21552DOI Listing
December 2007

Loss of HSulf-1 expression enhances autocrine signaling mediated by amphiregulin in breast cancer.

J Biol Chem 2007 May 15;282(19):14413-20. Epub 2007 Mar 15.

Department of Laboratory Medicine and Experimental Pathology, Mayo Clinic Cancer Center, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1074/jbc.M611395200DOI Listing
May 2007

A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.

Science 2006 Nov 19;314(5801):992-3. Epub 2006 Oct 19.

Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.1126/science.1133811DOI Listing
November 2006

DIXDC1 isoform, l-DIXDC1, is a novel filamentous actin-binding protein.

Biochem Biophys Res Commun 2006 Aug 19;347(1):22-30. Epub 2006 Jun 19.

Department of Laboratory Medicine and Pathology, Mayo Clinic/Mayo Medical School, Rochester, MN 55905, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0601284
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http://dx.doi.org/10.1016/j.bbrc.2006.06.050DOI Listing
August 2006

Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity.

J Clin Invest 2006 Jul 8;116(7):1994-2004. Epub 2006 Jun 8.

Department of Laboratory Medicine and Experimental Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA, Medical Oncology Unit and Department of Histopathology, San Salvatore Hospital, Pesaro, Italy.

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http://www.jci.org/cgi/doi/10.1172/JCI27698
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http://dx.doi.org/10.1172/JCI27698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474818PMC
July 2006

HSulf-1 inhibits angiogenesis and tumorigenesis in vivo.

Cancer Res 2006 Jun;66(12):6025-32

Department of Experimental Pathology, Mayo Clinic Cancer Center, Rochester, Minnesota 55905, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-3582DOI Listing
June 2006

Heterozygous ATR mutations in mismatch repair-deficient cancer cells have functional significance.

Cancer Res 2005 Aug;65(16):7091-5

Department of Obstetrics and Gynecology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-1019DOI Listing
August 2005

Epigenetic silencing of TCEAL7 (Bex4) in ovarian cancer.

Oncogene 2005 Jul;24(32):5089-100

Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic/Foundation, 200 First Street, SW Rochester, MN 55905, USA.

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http://www.nature.com/articles/1208700
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http://dx.doi.org/10.1038/sj.onc.1208700DOI Listing
July 2005

A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer.

Oncogene 2004 Feb;23(8):1636-44

Mayo Clinic Cancer Center and Department of Experimental Pathology, Mayo Clinic, Rochester, MN 55905, USA.

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http://www.nature.com/articles/1207271
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http://dx.doi.org/10.1038/sj.onc.1207271DOI Listing
February 2004

HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma.

Oncogene 2004 Feb;23(7):1439-47

Division of Gastroenterology and Hepatology, Mayo Clinic Cancer Center, Mayo Clinic and Foundation, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1038/sj.onc.1207258DOI Listing
February 2004

Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer.

J Biol Chem 2003 Jun 9;278(25):23107-17. Epub 2003 Apr 9.

Mayo Clinic Cancer Center, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M302203200
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http://dx.doi.org/10.1074/jbc.M302203200DOI Listing
June 2003

Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization.

Cancer Res 2002 Jan;62(1):262-70

Department of Experimental Pathology, Division of Laboratory Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.

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January 2002