Publications by authors named "Jeremy Chen"

100Publications

Pharmacophore-based virtual screening for the identification of the novel Src inhibitor SJG-136 against lung cancer cell growth and motility.

Am J Cancer Res 2020 1;10(6):1668-1690. Epub 2020 Jun 1.

Institute of Biomedical Sciences, National Chung Hsing University Taichung, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339285PMC
June 2020

4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin.

Eur J Med Chem 2019 Nov 2;181:111584. Epub 2019 Aug 2.

Program in Molecular Medicine, National Yang-Ming University and Academia Sinica, Taipei, Taiwan; Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan; Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, 100, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2019.111584DOI Listing
November 2019

High PD-L1 expression correlates with primary resistance to EGFR-TKIs in treatment naïve advanced EGFR-mutant lung adenocarcinoma patients.

Lung Cancer 2019 01 20;127:37-43. Epub 2018 Nov 20.

Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, No. 155, Sect. 2, Linong St., Taipei, 112, Taiwan; Comprehensive Cancer Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183064
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http://dx.doi.org/10.1016/j.lungcan.2018.11.021DOI Listing
January 2019

Tissue plasminogen activator and neuropathy open the blood-nerve barrier with upregulation of microRNA-155-5p in male rats.

Biochim Biophys Acta Mol Basis Dis 2019 06 6;1865(6):1160-1169. Epub 2019 Jan 6.

Dept. of Anesthesiology, University Hospital of Würzburg, 97080 Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2019.01.008DOI Listing
June 2019

Transitions of the Understanding and Definition of Primary Glaucoma.

Chin Med J (Engl) 2018 Dec;131(23):2852-2859

Department of Glaucoma, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, Guangdong 510060, China.

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http://dx.doi.org/10.4103/0366-6999.246069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278182PMC
December 2018

Prolonging pulse duration in ultrasound-mediated gene delivery lowers acoustic pressure threshold for efficient gene transfer to cells and small animals.

J Control Release 2018 06 24;279:345-354. Epub 2018 Apr 24.

Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101, USA; Department of Pediatrics, University of Washington, Seattle, WA 98195, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01683659183019
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http://dx.doi.org/10.1016/j.jconrel.2018.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110264PMC
June 2018

AC-93253 iodide, a novel Src inhibitor, suppresses NSCLC progression by modulating multiple Src-related signaling pathways.

J Hematol Oncol 2017 Nov 13;10(1):172. Epub 2017 Nov 13.

Institute of Biomedical Sciences, National Chung Hsing University, No. 145, Xingda Rd., South Dist, Taichung, 40227, Taiwan, Republic of China.

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http://dx.doi.org/10.1186/s13045-017-0539-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683468PMC
November 2017

Astrocyte-elevated gene-1 confers resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase expression.

Oncotarget 2017 Sep 28;8(37):61901-61916. Epub 2017 Jun 28.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.18632/oncotarget.18717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617473PMC
September 2017

Study of the inhibitory effects on TNF-α-induced NF-κB activation of IMD0354 analogs.

Chem Biol Drug Des 2017 Dec 11;90(6):1307-1311. Epub 2017 Jul 11.

Department of Chemistry, Tunghai University, Taichung, Taiwan.

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http://dx.doi.org/10.1111/cbdd.13032DOI Listing
December 2017

HOXA5 and p53 cooperate to suppress lung cancer cell invasion and serve as good prognostic factors in non-small cell lung cancer.

J Cancer 2017 9;8(6):1071-1081. Epub 2017 Apr 9.

Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei, Taiwan.

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http://dx.doi.org/10.7150/jca.17295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436261PMC
April 2017

Suppressive effect of microRNA319 expression on rice plant height.

Theor Appl Genet 2017 Jul 3;130(7):1507-1518. Epub 2017 May 3.

Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan, ROC.

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http://dx.doi.org/10.1007/s00122-017-2905-5DOI Listing
July 2017

The protection role of Atg16l1 in CD11cdendritic cells in murine colitis.

Immunobiology 2017 07 16;222(7):831-841. Epub 2017 Mar 16.

Department of Gastroenterology, The Second Hospital of Hebei Medical University, Hebei, China. Electronic address:

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http://dx.doi.org/10.1016/j.imbio.2017.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610573PMC
July 2017

Cancer cells increase endothelial cell tube formation and survival by activating the PI3K/Akt signalling pathway.

J Exp Clin Cancer Res 2017 02 7;36(1):27. Epub 2017 Feb 7.

Institute of Biomedical Sciences, National Chung-Hsing University, Taichung, Taiwan.

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http://dx.doi.org/10.1186/s13046-017-0495-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296960PMC
February 2017

Inferring condition-specific targets of human TF-TF complexes using ChIP-seq data.

BMC Genomics 2017 01 10;18(1):61. Epub 2017 Jan 10.

Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan.

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http://dx.doi.org/10.1186/s12864-016-3450-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223348PMC
January 2017

Increased risk of community-acquired pneumonia in COPD patients with comorbid cardiovascular disease.

Int J Chron Obstruct Pulmon Dis 2016 5;11:3051-3058. Epub 2016 Dec 5.

Department of Internal Medicine, Division of Chest Medicine, Changhua Christian Hospital, Changhua; Department of Respiratory Care, College of Health Sciences, Chang Jung Christian University, Tainan; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.

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http://dx.doi.org/10.2147/COPD.S115137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147399PMC
August 2017

A New Era for Cancer Target Therapies: Applying Systems Biology and Computer-Aided Drug Design to Cancer Therapies.

Curr Pharm Biotechnol 2016;17(14):1246-1267

Laboratory of Control and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan.

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http://dx.doi.org/10.2174/1389201017666161019160606DOI Listing
February 2017

iTAR: a web server for identifying target genes of transcription factors using ChIP-seq or ChIP-chip data.

BMC Genomics 2016 08 12;17(1):632. Epub 2016 Aug 12.

Department of Genetics, Geisel School of Medicine at Dartmouth, Hanover, NH, 03755, USA.

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http://dx.doi.org/10.1186/s12864-016-2963-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983039PMC
August 2016

Oncogenic miR-137 contributes to cisplatin resistance via repressing CASP3 in lung adenocarcinoma.

Am J Cancer Res 2016 1;6(6):1317-30. Epub 2016 Jun 1.

Institute of Biomedical Sciences, National Chung-Hsing UniversityTaichung, Taiwan; Agricultural Biotechnology Center, National Chung Hsing UniversityTaichung, Taiwan; Rong Hsing Research Center for Translational Medicine, National Chung Hsing UniversityTaichung, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937735PMC
July 2016

Chidamide alleviates TGF-β-induced epithelial-mesenchymal transition in lung cancer cell lines.

Mol Biol Rep 2016 Jul 17;43(7):687-95. Epub 2016 May 17.

Institute of Biomedical Science, College of Life Sciences, National Chung Hsing University, 250, Guoguang Road, Taichung, 40227, Taiwan.

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http://dx.doi.org/10.1007/s11033-016-4005-zDOI Listing
July 2016

Developing Effective Salmonella-based Approaches to Treat Pancreatic Cancer.

Pancreat Disord Ther 2016;6(1):1-2

Department of Experimental Therapeutics, City of Hope, Duarte CA, USA.

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http://dx.doi.org/10.4172/2165-7092.1000167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764990PMC
January 2016

Predilection of contralateral upper lung metastasis in upper lobe lung adenocarcinoma patients.

J Thorac Dis 2016 Jan;8(1):86-92

1 Division of Chest Medicine, 2 Division of Critical Care and Respiratory Therapy, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan ; 3 Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan ; 4 Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan ; 5 Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan ; 6 Institute of Statistical Science, Academia Sinica, Taipei, Taiwan ; 7 NTU Center for Genomic Medicine, National Taiwan University College of Medicine, Taipei, Taiwan ; 8 Department of Pathology and Graduate Institute of Pathology, 9 Center for Optoelectronic Biomedicine, College of Medicine, National Taiwan University, Taipei, Taiwan ; 10 Graduate Institute of Toxicology, National Taiwan University, Taipei, Taiwan ; 11 Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan ; 12 Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung, Taiwan.

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http://dx.doi.org/10.3978/j.issn.2072-1439.2016.01.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740126PMC
January 2016

Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression.

Sci Rep 2015 Sep 24;5:14273. Epub 2015 Sep 24.

Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.1038/srep14273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585843PMC
September 2015

R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability.

J Clin Oncol 2015 Jul 8;33(20):2303-10. Epub 2015 Jun 8.

Hsuan-Yu Chen, Yi-Chiung Hsu, Chi-Sheng Chang, Yu-Cheng Li, Hao Ho, Ya-Hsuan Chang, Shinsheng Yuan, Chia-Hsin Liu, Guan-I Wu, and Ker-Chau Li, Institute of Statistical Science, and Shi-Yi Yang, Hwai-I Yang, and Chien-Jen Chen, Genomics Research Center, Academia Sinica; Hsuan-Yu Chen, Sung-Liang Yu, Bing-Ching Ho, Kang-Yi Su, and Pin-Yen Hsu, College of Medicine; Hsuan-Yu Chen, College of Life Science; Sung-Liang Yu, Kang-Yi Su, and Pan-Chyr Yang, Center of Genomic Medicine; Huei-Wen Chen, Graduate Institute of Toxicology, National Taiwan University; Sung-Liang Yu, Chong-Jen Yu, Kuan-Yu Chen, and Pan-Chyr Yang, National Taiwan University Hospital; Yuh-Min Chen, Taipei Veterans General Hospital; Chung-Ping Hsu, Tsung-Ying Yang, and Gee-Chen Chang, School of Medicine, National Yang-Ming University; Mei-Hsuan Lee, Institute of Clinical Medicine, National Yang-Ming University, Taipei; Chih-Yi Chen, Chung Shan Medical University; Chung-Ping Hsu, Tsung-Ying Yang, Kun-Chieh Chen, Kuo-Hsuan Hsu, Jeng-Sen Tseng, Jiun-Yi Hsia, Cheng-Yen Chuang, and Gee-Chen Chang, Taichung Veterans General Hospital; Kun-Chieh Chen, Kuo-Hsuan Hsu, Jeng-Sen Tseng, and Jeremy J.W. Chen, Institute of Biomedical Sciences, National Chung-Hsing University; Gee-Chen Chang, Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung; Chao A. Hsiung, Institute of Population Health Sciences, National Health Research Institutes, Zhunan; Chih-Liang Wang, Chang Gung Memorial Hospital, Tao-Yuan; Ying-Huang Tsai, Chang-Gung Memorial Hospital, Chia-Yi; Ming-Shyan Huang, Kaohsiung Medical University Hospital, College of Medicine, Kaohsiung Medical University, Kaohsiung; Wu-Chou Su, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; and Ker-Chau Li, University of California Los Angeles, Los Angeles, CA.

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http://dx.doi.org/10.1200/JCO.2014.59.3590DOI Listing
July 2015

Digoxin Suppresses Tumor Malignancy through Inhibiting Multiple Src-Related Signaling Pathways in Non-Small Cell Lung Cancer.

PLoS One 2015 8;10(5):e0123305. Epub 2015 May 8.

Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan; Agricultural Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123305PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425490PMC
February 2016

Transcriptome-wide analysis of the MADS-box gene family in the orchid Erycina pusilla.

Plant Biotechnol J 2016 Jan 28;14(1):284-98. Epub 2015 Apr 28.

Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan.

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http://doi.wiley.com/10.1111/pbi.12383
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http://dx.doi.org/10.1111/pbi.12383DOI Listing
January 2016

NDH expression marks major transitions in plant evolution and reveals coordinate intracellular gene loss.

BMC Plant Biol 2015 Apr 11;15:100. Epub 2015 Apr 11.

Agricultural Biotechnology Research Center of Academia Sinica, Agricultural Technology Building, No. 128, Sec. 2, Academia Road, Nankang, Taipei, 115, Taiwan.

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http://dx.doi.org/10.1186/s12870-015-0484-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404220PMC
April 2015

HOXA5 inhibits metastasis via regulating cytoskeletal remodelling and associates with prolonged survival in non-small-cell lung carcinoma.

PLoS One 2015 14;10(4):e0124191. Epub 2015 Apr 14.

Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan; Agricultural Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124191PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396855PMC
April 2016

Identification of five driver gene mutations in patients with treatment-naïve lung adenocarcinoma in Taiwan.

PLoS One 2015 19;10(3):e0120852. Epub 2015 Mar 19.

Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120852PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366385PMC
December 2015

PARVA promotes metastasis by modulating ILK signalling pathway in lung adenocarcinoma.

PLoS One 2015 4;10(3):e0118530. Epub 2015 Mar 4.

Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan; Center of Genomic Medicine, National Taiwan University, Taipei, Taiwan; Center for Optoelectronic Biomedicine, College of Medicine, National Taiwan University, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118530PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349696PMC
January 2016

Dynamic plasma EGFR mutation status as a predictor of EGFR-TKI efficacy in patients with EGFR-mutant lung adenocarcinoma.

J Thorac Oncol 2015 Apr;10(4):603-10

*Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan, ROC; †Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; ‡Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; §Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; ‖Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan, ROC; ¶Division of Critical Care and Respiratory Therapy, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; #Institute of Statistical Science, Academia Sinica, Taipei, Taiwan, ROC; **Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC; ††Center for Optoelectronic Biomedicine, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC; ‡‡Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC; §§Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC; ‖‖Center of Genomic Medicine, National Taiwan University, Taipei, Taiwan, ROC; and ¶¶Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.

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http://dx.doi.org/10.1097/JTO.0000000000000443DOI Listing
April 2015

Tumour suppressor HLJ1: A potential diagnostic, preventive and therapeutic target in non-small cell lung cancer.

World J Clin Oncol 2014 Dec;5(5):865-73

Meng-Feng Tsai, Department of Molecular Biotechnology, Dayeh University, Changhua 51591, Taiwan.

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http://dx.doi.org/10.5306/wjco.v5.i5.865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259948PMC
December 2014

Prior EGFR tyrosine-kinase inhibitor therapy did not influence the efficacy of subsequent pemetrexed plus platinum in advanced chemonaïve patients with EGFR-mutant lung adenocarcinoma.

Onco Targets Ther 2014 23;7:799-805. Epub 2014 May 23.

Institute of Biomedical Sciences, National Chung-Hsing University, Taichung, Taiwan ; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan ; School of Medicine, China Medical University, Taichung, Taiwan ; Comprehensive Cancer Center, Taichung Veterans General Hospital, Taichung, Taiwan ; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.2147/OTT.S62639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043805PMC
June 2014

The transcriptional repression activity of STAF65γ is facilitated by promoter tethering and nuclear import of class IIa histone deacetylases.

Biochim Biophys Acta 2014 Jul 19;1839(7):579-91. Epub 2014 May 19.

Institute of Molecular Biology, National Chung Hsing University, Taichung 40227, Taiwan; Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung 40227, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2014.05.007DOI Listing
July 2014

Antihelminthic niclosamide modulates dendritic cells activation and function.

Cell Immunol 2014 Mar-Apr;288(1-2):15-23. Epub 2013 Dec 28.

Institute of Biomedical Science, National Chung-Hsing University, Taichung, Taiwan, ROC; Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taiwan, ROC; Department of Medical Research and Education, Taichung Veterans General Hospital, Taichung, Taiwan, ROC; Division of Chest Medicine, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2013.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7094312PMC
May 2014

Discovering chromatin motifs using FAIRE sequencing and the human diploid genome.

BMC Genomics 2013 May 8;14:310. Epub 2013 May 8.

Institute of Molecular Biology, National Chung Hsing University, Taiwan, ROC.

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http://dx.doi.org/10.1186/1471-2164-14-310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655836PMC
May 2013

SUSTAINED TL1A EXPRESSION ON BOTH LYMPHOID AND MYELOID CELLS LEADS TO MILD SPONTANEOUS INTESTINAL INFLAMMATION AND FIBROSIS.

Eur J Microbiol Immunol (Bp) 2013 Mar;3(1):11-20

F. Widjaja Foundation, Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA ; Department of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, China.

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http://www.akademiai.com/doi/abs/10.1556/EuJMI.3.2013.1.2
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http://dx.doi.org/10.1556/EuJMI.3.2013.1.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638202PMC
March 2013

The HLJ1-targeting drug screening identified Chinese herb andrographolide that can suppress tumour growth and invasion in non-small-cell lung cancer.

Carcinogenesis 2013 May 9;34(5):1069-80. Epub 2013 Jan 9.

Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan, Republic of China.

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http://dx.doi.org/10.1093/carcin/bgt005DOI Listing
May 2013

Effect of molecular weight, acid, and plasticizer on the physicochemical and antibacterial properties of β-chitosan based films.

J Food Sci 2012 May;77(5):E127-36

Dept. of Food Science and Technology, Oregon State Univ., Corvallis, OR 97331, USA.

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http://dx.doi.org/10.1111/j.1750-3841.2012.02686.xDOI Listing
May 2012

A novel function of YWHAZ/β-catenin axis in promoting epithelial-mesenchymal transition and lung cancer metastasis.

Mol Cancer Res 2012 Oct 21;10(10):1319-31. Epub 2012 Aug 21.

Institute of Biomedical Sciences, National Chung Hsing University, Taichung 40227, Taiwan, ROC.

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http://dx.doi.org/10.1158/1541-7786.MCR-12-0189DOI Listing
October 2012

Recombinant lipidated HPV E7 induces a Th-1-biased immune response and protective immunity against cervical cancer in a mouse model.

PLoS One 2012 18;7(7):e40970. Epub 2012 Jul 18.

National Institute of Infectious Disease and Vaccinology, National Health Research Institutes, Zhunan Town, Miaoli, Taiwan, Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040970PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399806PMC
January 2013

Comparative proteomic profiling of human lung adenocarcinoma cells (CL 1-0) expressing miR-372.

Electrophoresis 2012 Feb;33(4):675-88

Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan.

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http://doi.wiley.com/10.1002/elps.201100329
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http://dx.doi.org/10.1002/elps.201100329DOI Listing
February 2012

Inflammatory Bowel Disease Associated Colorectal Neoplasia.

J Gastrointest Dig Syst 2012 Jan;Suppl 8:002

Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.4172/2161-069X.S8-002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970563PMC
January 2012

Differential effects of alpha-particle radiation and x-irradiation on genes associated with apoptosis.

Radiol Res Pract 2011 9;2011:679806. Epub 2011 Jun 9.

Consumer and Clinical Radiation Protection Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, 775 Brookfield Road, PL 6303B, Ottawa, ON, Canada K1A 0K9.

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http://dx.doi.org/10.1155/2011/679806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199915PMC
November 2011

Single-walled carbon nanotubes induce airway hyperreactivity and parenchymal injury in mice.

Am J Respir Cell Mol Biol 2012 Feb 29;46(2):257-67. Epub 2011 Sep 29.

Graduate Institute of Toxicology, National Taiwan University College of Medicine, No. 1 Sec. 1 Ren-Ai Road, Taipei, Taiwan.

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http://dx.doi.org/10.1165/rcmb.2011-0010OCDOI Listing
February 2012

Substance P induces CCN1 expression via histone deacetylase activity in human colonic epithelial cells.

Am J Pathol 2011 Nov 23;179(5):2315-26. Epub 2011 Sep 23.

Inflammatory Bowel Disease Center, Division of Digestive Diseases, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000294401100760
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http://dx.doi.org/10.1016/j.ajpath.2011.07.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204086PMC
November 2011

Cathelicidin signaling via the Toll-like receptor protects against colitis in mice.

Gastroenterology 2011 Nov 14;141(5):1852-63.e1-3. Epub 2011 Jul 14.

Inflammatory Bowel Disease Center, Division of Digestive Diseases, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1053/j.gastro.2011.06.079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199285PMC
November 2011

Terpinen-4-ol Induces Apoptosis in Human Nonsmall Cell Lung Cancer In Vitro and In Vivo.

Evid Based Complement Alternat Med 2012 20;2012:818261. Epub 2011 Jun 20.

Department of Dermatology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

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http://dx.doi.org/10.1155/2012/818261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133878PMC
November 2011

microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma.

Cancer Res 2010 Oct 30;70(20):7841-50. Epub 2010 Aug 30.

Graduate Institute of Life Science, National Defense Medical Center, and Genomics Research Center, Academia Sinica, Taipei, Taiwan.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095771PMC
October 2010

Acidic stress facilitates tyrosine phosphorylation of HLJ1 to associate with actin cytoskeleton in lung cancer cells.

Exp Cell Res 2010 Oct 13;316(17):2910-21. Epub 2010 Jul 13.

Department of Life Science, National Chung Hsing University, Taichung, Taiwan.

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http://dx.doi.org/10.1016/j.yexcr.2010.06.027DOI Listing
October 2010

HLJ1 is a novel caspase-3 substrate and its expression enhances UV-induced apoptosis in non-small cell lung carcinoma.

Nucleic Acids Res 2010 Oct 21;38(18):6148-58. Epub 2010 May 21.

Department of Life Science, Institutes of Biomedical Sciences and Molecular Biology, National Chung Hsing University, Taichung, Taiwan.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkq412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952861PMC
October 2010

Tumor suppressor HLJ1 binds and functionally alters nucleophosmin via activating enhancer binding protein 2alpha complex formation.

Cancer Res 2010 Feb 9;70(4):1656-67. Epub 2010 Feb 9.

Institutes of Biomedical Sciences and Molecular Biology, National Chung Hsing University, Taiwan 40227,ROC.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-09-2453DOI Listing
February 2010

Mechanical stretch induces endothelial nitric oxide synthase gene expression in neonatal rat cardiomyocytes.

Clin Exp Pharmacol Physiol 2009 May 28;36(5-6):559-66. Epub 2008 Oct 28.

Department of Biological Science and Technology, China Medical University, Taichung, Taiwan.

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http://dx.doi.org/10.1111/j.1440-1681.2008.05100.xDOI Listing
May 2009

Anticancer effects of tanshinone I in human non-small cell lung cancer.

Mol Cancer Ther 2008 Nov;7(11):3527-38

Institutes of Biomedical Sciences and Molecular Biology, National Chung-Hsing University, Taichung, Taiwan 40227, Republic of China.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-2288DOI Listing
November 2008

Automatic determination of arterial input function for dynamic contrast enhanced MRI in tumor assessment.

Med Image Comput Comput Assist Interv 2008 ;11(Pt 1):594-601

Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587281PMC
http://dx.doi.org/10.1007/978-3-540-85988-8_71DOI Listing
December 2008

T-DNA activation tagging as a tool to isolate Salvia miltiorrhiza transgenic lines for higher yields of tanshinones.

Planta Med 2008 Jun 26;74(7):780-6. Epub 2008 May 26.

Department of Agronomy, National Chung-Hsing University Taichung, Taiwan.

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http://dx.doi.org/10.1055/s-2008-1074527DOI Listing
June 2008

Intra-abdominal adhesion formation induces anti-oxidative injury, enhances cell proliferation, and prevents complement-mediated lysis.

Wound Repair Regen 2008 May-Jun;16(3):388-98

Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, Taiwan.

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http://doi.wiley.com/10.1111/j.1524-475X.2008.00378.x
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July 2008

Pathophysiology of tumor-associated macrophages.

Adv Clin Chem 2008 ;45:199-223

Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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June 2008

Expression of a Bacillus thuringiensis toxin (cry1Ab) gene in cabbage (Brassica oleracea L. var. capitata L.) chloroplasts confers high insecticidal efficacy against Plutella xylostella.

Theor Appl Genet 2008 Jun 16;117(1):75-88. Epub 2008 Apr 16.

Department of Post-Modern Agriculture, Ming Dao University, Chang Hua, 523, Taiwan ROC.

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http://dx.doi.org/10.1007/s00122-008-0754-yDOI Listing
June 2008

Combined differential gene expression profile and pathway enrichment analyses to elucidate the molecular mechanisms of uterine leiomyoma after gonadotropin-releasing hormone treatment.

Fertil Steril 2008 Oct 7;90(4):1219-25. Epub 2008 Feb 7.

Department of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.fertnstert.2007.11.015DOI Listing
October 2008

MicroRNA signature predicts survival and relapse in lung cancer.

Cancer Cell 2008 Jan;13(1):48-57

Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University College of Medicine, Taipei, Taiwan 100, Republic of China.

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http://dx.doi.org/10.1016/j.ccr.2007.12.008DOI Listing
January 2008

Stable chloroplast transformation in cabbage (Brassica oleracea L. var. capitata L.) by particle bombardment.

Plant Cell Rep 2007 Oct 14;26(10):1733-44. Epub 2007 Jun 14.

Department of Post-Modern Agriculture, Ming Dao University, Chang Hua 523, Taiwan, ROC.

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http://dx.doi.org/10.1007/s00299-007-0374-zDOI Listing
October 2007

Synergistic activation of the tumor suppressor, HLJ1, by the transcription factors YY1 and activator protein 1.

Cancer Res 2007 May;67(10):4816-26

NTU Center for Genomic Medicine, National Taiwan University, Taipei, Taiwan, Republic of China.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-0504DOI Listing
May 2007

Unique MicroRNA signature and clinical outcome of cancers.

DNA Cell Biol 2007 May;26(5):283-92

Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1089/dna.2006.0555DOI Listing
May 2007