Jens Pietzsch, PhD, MD - Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research - Professor, Head of Department

Jens Pietzsch

PhD, MD

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research

Professor, Head of Department

Dresden, Saxony | Germany

Main Specialties: Chemistry, Nuclear Medicine, Oncology, Pharmacology

Additional Specialties: Small animal imaging

ORCID logohttps://orcid.org/0000-0002-1610-1493

Jens Pietzsch, PhD, MD - Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research - Professor, Head of Department

Jens Pietzsch

PhD, MD

Introduction

Primary Affiliation: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research - Dresden, Saxony , Germany

Specialties:

Additional Specialties:

Research Interests:

Publications

182Publications

2325Reads

6Profile Views

Radiopharmacologist's and Radiochemist's View on Targeting the Eph/Ephrin Receptor Tyrosine Kinase System.

ACS Omega 2020 Jul 17;5(27):16318-16331. Epub 2020 Jun 17.

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Department of Radiopharmaceutical and Chemical Biology, 01328 Dresden, Germany.

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http://dx.doi.org/10.1021/acsomega.0c01058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364440PMC
July 2020

Adjuvant Drug-Assisted Bone Healing: Advances and Challenges in Drug Delivery Approaches.

Pharmaceutics 2020 May 6;12(5). Epub 2020 May 6.

Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.

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http://dx.doi.org/10.3390/pharmaceutics12050428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284517PMC
May 2020

Synthesis, radiolabelling and initial biological characterisation of F-labelled xanthine derivatives for PET imaging of Eph receptors.

Org Biomol Chem 2020 04;18(16):3104-3116

Helmholtz-Zentrum Dresden-Rossendorf, Institut für Radiopharmazeutische Krebsforschung, Bautzner Landstraße 400, D-01328 Dresden, Germany. and Technische Universität Dresden, Fakultät Chemie und Lebensmittelchemie, D-01062 Dresden, Germany.

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http://dx.doi.org/10.1039/d0ob00391cDOI Listing
April 2020
3.562 Impact Factor

Adjuvant drug-assisted bone healing: Part III - Further strategies for local and systemic modulation.

Clin Hemorheol Microcirc 2019 ;73(3):439-488

Department of Radiopharmaceutical and Chemical Biology, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Dresden, Germany.

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http://dx.doi.org/10.3233/CH-199104DOI Listing
March 2020
3 Reads
2.242 Impact Factor

Adjuvant drug-assisted bone healing: Part I - Modulation of inflammation.

Clin Hemorheol Microcirc 2019 ;73(3):381-408

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Department of Radiopharmaceutical and Chemical Biology, Dresden, Germany.

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http://dx.doi.org/10.3233/CH-199102DOI Listing
March 2020
13 Reads
2.242 Impact Factor

Adjuvant drug-assisted bone healing: Part II - Modulation of angiogenesis.

Clin Hemorheol Microcirc 2019 ;73(3):409-438

Department of Radiopharmaceutical and Chemical Biology, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Dresden, Germany.

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http://dx.doi.org/10.3233/CH-199103DOI Listing
March 2020
22 Reads
2.242 Impact Factor

Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging.

Small 2020 Feb 26;16(7):e1905013. Epub 2019 Dec 26.

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden - Rossendorf, Bautzner Landstrasse 400, D-01328, Dresden, Germany.

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http://dx.doi.org/10.1002/smll.201905013DOI Listing
February 2020
8.368 Impact Factor

Synthesis and Cyclooxygenase Inhibition of Sulfonamide-Substituted (Dihydro)Pyrrolo[3,2,1-]indoles and Their Potential Prodrugs.

Molecules 2019 Oct 22;24(20). Epub 2019 Oct 22.

Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstrasse 400, 01328 Dresden, Germany.

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http://dx.doi.org/10.3390/molecules24203807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832141PMC
October 2019
2.416 Impact Factor

Current Management of Pheochromocytoma/Paraganglioma: A Guide for the Practicing Clinician in the Era of Precision Medicine.

Cancers (Basel) 2019 Oct 8;11(10). Epub 2019 Oct 8.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.3390/cancers11101505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827093PMC
October 2019
2 Reads

Nitric Oxide-Releasing Selective Estrogen Receptor Modulators: A Bifunctional Approach to Improve the Therapeutic Index.

J Med Chem 2019 07 4;62(14):6525-6539. Epub 2019 Jun 4.

Institute of Radiopharmaceutical Cancer Research, Department of Radiopharmaceutical and Chemical Biology , Helmholtz-Zentrum Dresden-Rossendorf , 01328 Dresden , Germany.

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http://dx.doi.org/10.1021/acs.jmedchem.9b00171DOI Listing
July 2019
1 Read
5.447 Impact Factor

Fluorine-18 Labeling of S100 Proteins for Small Animal Positron Emission Tomography.

Methods Mol Biol 2019 ;1929:461-485

Department of Radiopharmaceutical and Chemical Biology, Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany.

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http://dx.doi.org/10.1007/978-1-4939-9030-6_29DOI Listing
July 2019

Synthesis and preliminary radiopharmacological characterisation of an C-labelled azadipeptide nitrile as potential PET tracer for imaging of cysteine cathepsins.

J Labelled Comp Radiopharm 2019 06 15;62(8):448-459. Epub 2019 May 15.

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1002/jlcr.3729DOI Listing
June 2019
17 Reads
1.187 Impact Factor

Radiochemical and radiopharmacological characterization of a Cu-labeled α-MSH analog conjugated with different chelators.

J Labelled Comp Radiopharm 2019 06 17;62(8):495-509. Epub 2019 Jun 17.

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1002/jlcr.3728DOI Listing
June 2019
2 Reads
1.187 Impact Factor

Targeting Cyclooxygenase-2 in Pheochromocytoma and Paraganglioma: Focus on Genetic Background.

Cancers (Basel) 2019 May 28;11(6). Epub 2019 May 28.

Department of Radiopharmaceutical and Chemical Biology, Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.

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http://dx.doi.org/10.3390/cancers11060743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627450PMC
May 2019
30 Reads

Impact of Extrinsic and Intrinsic Hypoxia on Catecholamine Biosynthesis in Absence or Presence of Hif2α in Pheochromocytoma Cells.

Cancers (Basel) 2019 Apr 28;11(5). Epub 2019 Apr 28.

Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.3390/cancers11050594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562431PMC
April 2019
6 Reads

Carboranyl Analogues of Celecoxib with Potent Cytostatic Activity against Human Melanoma and Colon Cancer Cell Lines.

ChemMedChem 2019 02 23;14(3):315-321. Epub 2019 Jan 23.

Institut für Anorganische Chemie, Universität Leipzig, Johannisallee 29, 04103, Leipzig, Germany.

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http://dx.doi.org/10.1002/cmdc.201800685DOI Listing
February 2019
29 Reads
2.968 Impact Factor

Synthesis, F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide.

Amino Acids 2019 Feb 27;51(2):219-244. Epub 2018 Sep 27.

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden Rossendorf, Bautzner Landstraße 400, 01328, Dresden, Germany.

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http://dx.doi.org/10.1007/s00726-018-2657-9DOI Listing
February 2019
31 Reads
3.293 Impact Factor

Regulation of bone regeneration.

Clin Hemorheol Microcirc 2019 ;73(3):379-380

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Radiopharmaceutical and Chemical Biology, Dresden, Germany.

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http://dx.doi.org/10.3233/CH-199101DOI Listing
January 2019
1 Read
2.242 Impact Factor

Diverse effects of phospholipase A2 receptor expression on LNCaP and PC-3 prostate cancer cell growth and .

Oncotarget 2018 Nov 13;9(89):35983-35996. Epub 2018 Nov 13.

Technische Universität Dresden, Carl Gustav Carus University Hospital Dresden, Institute of Clinical Chemistry and Laboratory Medicine, 01307 Dresden, Germany.

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http://dx.doi.org/10.18632/oncotarget.26316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267604PMC
November 2018
6.359 Impact Factor

Exploring pitfalls of Cu-labeled EGFR-targeting peptide GE11 as a potential PET tracer.

Amino Acids 2018 Oct 23;50(10):1415-1431. Epub 2018 Jul 23.

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, 01328, Dresden, Germany.

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http://dx.doi.org/10.1007/s00726-018-2616-5DOI Listing
October 2018
30 Reads
3.293 Impact Factor

Strain-specific metastatic phenotypes in pheochromocytoma allograft mice

Endocr Relat Cancer 2018 10 5;25(12):993-1004. Epub 2018 Oct 5.

Department of Radiopharmaceutical and Chemical Biology, Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany.

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https://erc.bioscientifica.com/view/journals/erc/25/12/ERC-1
Publisher Site
http://dx.doi.org/10.1530/ERC-18-0136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176113PMC
October 2018
60 Reads
4.805 Impact Factor

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells.

Blood Cancer J 2018 08 22;8(9):81. Epub 2018 Aug 22.

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Dresden, Germany.

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http://dx.doi.org/10.1038/s41408-018-0113-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127150PMC
August 2018
2.884 Impact Factor

Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology.

J Autoimmun 2018 06 2;90:116-131. Epub 2018 Mar 2.

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Bautzner Landstraße 400, 01328 Dresden, Germany; Tumor Immunology, UniversityCancerCenter (UCC), 'Carl Gustav Carus' Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany; German Cancer Consortium (DKTK), Partner Site Dresden, Fetscherstr. 74, 01307 Dresden, Germany; German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; National Center for Tumor Diseases (NCT), 'Carl Gustav Carus' Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden, Technische Universität Dresden, Fetscherstraße 105, 01307 Dresden, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411173073
Publisher Site
http://dx.doi.org/10.1016/j.jaut.2018.02.006DOI Listing
June 2018
33 Reads
8.410 Impact Factor

Synthesis, Characterization, and Initial Biological Evaluation of [ Tc]Tc-Tricarbonyl-labeled DPA-α-MSH Peptide Derivatives for Potential Melanoma Imaging.

ChemMedChem 2018 06 23;13(11):1146-1158. Epub 2018 Apr 23.

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 01328, Dresden, Germany.

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http://dx.doi.org/10.1002/cmdc.201800110DOI Listing
June 2018
7 Reads
2.968 Impact Factor

Causative treatment of acid aspiration induced acute lung injury - Recent trends from animal experiments and critical perspective.

Clin Hemorheol Microcirc 2018 ;69(1-2):187-195

Department of Anesthesia and Intensive Care, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.3233/CH-189113DOI Listing
June 2018
6 Reads
2.242 Impact Factor

N-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling.

J Med Chem 2018 05 10;61(10):4528-4560. Epub 2018 May 10.

Institut für Radiopharmazeutische Krebsforschung , Helmholtz-Zentrum Dresden-Rossendorf , Bautzner Landstraße 400 , 01328 Dresden , Germany.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00286DOI Listing
May 2018
5 Reads
5.447 Impact Factor

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells and .

Oncotarget 2018 May 22;9(39):25597-25616. Epub 2018 May 22.

UniversityCancerCenter (UCC) Dresden, Tumor Immunology, 'Carl Gustav Carus' Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.18632/oncotarget.25390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986651PMC
May 2018
4 Reads
6.359 Impact Factor

Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity.

Medchemcomm 2018 Mar 13;9(3):534-544. Epub 2018 Feb 13.

Department of Radiopharmaceutical and Chemical Biology , Helmholtz-Zentrum Dresden-Rossendorf , Institute of Radiopharmaceutical Cancer Research , Bautzner Landstraße 400 , 01328 Dresden , Germany . Email:

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http://dx.doi.org/10.1039/c7md00575jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072335PMC
March 2018
2 Reads
2.495 Impact Factor

Bridging from Brain to Tumor Imaging: (S)-(-)- and (R)-(+)-[F]Fluspidine for Investigation of Sigma-1 Receptors in Tumor-Bearing Mice.

Molecules 2018 Mar 20;23(3). Epub 2018 Mar 20.

Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 01328 Dresden, Germany.

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http://dx.doi.org/10.3390/molecules23030702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017399PMC
March 2018
5 Reads
2.416 Impact Factor

Correction: Novel valdecoxib derivatives by ruthenium(ii)-promoted 1,3-dipolar cycloaddition of nitrile oxides with alkynes - synthesis and COX-2 inhibition activity.

Medchemcomm 2018 03 7;9(3):591-592. Epub 2018 Mar 7.

Department of Radiopharmaceutical and Chemical Biology , Helmholtz-Zentrum Dresden-Rossendorf , Institute of Radiopharmaceutical Cancer Research , Bautzner Landstraße 400 , 01328 Dresden , Germany . Email:

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http://dx.doi.org/10.1039/c8md90011fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144543PMC
March 2018
2.495 Impact Factor

Overexpression of Receptor Tyrosine Kinase EphB4 Triggers Tumor Growth and Hypoxia in A375 Melanoma Xenografts: Insights from Multitracer Small Animal Imaging Experiments.

Molecules 2018 02 17;23(2). Epub 2018 Feb 17.

Department Radiopharmaceutical and Chemical Biology, Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01314 Dresden, Germany.

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http://dx.doi.org/10.3390/molecules23020444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017846PMC
February 2018
1 Read
2.416 Impact Factor

Technetium-99m based small molecule radiopharmaceuticals and radiotracers targeting inflammation and infection.

Dalton Trans 2017 Oct;46(42):14435-14451

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.

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http://dx.doi.org/10.1039/c7dt01735aDOI Listing
October 2017
5 Reads
4.197 Impact Factor

Gelatin-based Hydrogel Degradation and Tissue Interaction : Insights from Multimodal Preclinical Imaging in Immunocompetent Nude Mice.

Theranostics 2016 12;6(12):2114-2128. Epub 2016 Sep 12.

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Radiopharmaceutical and Chemical Biology, Dresden, Germany;; Technische Universität Dresden, Department of Chemistry and Food Chemistry, Dresden, Germany.

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http://dx.doi.org/10.7150/thno.16614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039684PMC
October 2017
16 Reads
7.827 Impact Factor

Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor.

J Labelled Comp Radiopharm 2017 08 2;60(10):489-498. Epub 2017 Aug 2.

Institut für Radiopharmazeutische Krebsforschung, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1002/jlcr.3526DOI Listing
August 2017
30 Reads
1.187 Impact Factor

Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.

J Pept Sci 2017 Jul 23;23(7-8):597-609. Epub 2017 Mar 23.

Department für Chemie, Institut für Biochemie, Mathematisch-Naturwissenschaftliche Fakultät, Universität zu Köln, Zülpicher Str. 47a, D-50674, Köln, Germany.

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http://dx.doi.org/10.1002/psc.2995DOI Listing
July 2017
18 Reads
1.546 Impact Factor

Surface charge and particle size determine the metabolic fate of dendritic polyglycerols.

Nanoscale 2017 Jun;9(25):8723-8739

Helmholtz-Zentrum Dresden - Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, D-01328 Dresden, Germany.

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http://dx.doi.org/10.1039/c7nr01702bDOI Listing
June 2017
37 Reads
7.394 Impact Factor

Novel Tumor Pretargeting System Based on Complementary l-Configured Oligonucleotides.

Bioconjug Chem 2017 04 22;28(4):1176-1188. Epub 2017 Mar 22.

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research , Bautzner Landstrasse 400, 01328 Dresden, Germany.

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http://dx.doi.org/10.1021/acs.bioconjchem.7b00045DOI Listing
April 2017
18 Reads
4.513 Impact Factor

Human Endothelial Cell Models in Biomaterial Research.

Trends Biotechnol 2017 03 24;35(3):265-277. Epub 2016 Oct 24.

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department Radiopharmaceutical and Chemical Biology, Dresden, Germany; Technische Universität Dresden, Department of Chemistry and Food Chemistry, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.tibtech.2016.09.007DOI Listing
March 2017
14 Reads
11.958 Impact Factor

Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity.

Amino Acids 2017 01 12;49(1):183-191. Epub 2016 Oct 12.

Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1007/s00726-016-2349-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241339PMC
January 2017
5 Reads
3.293 Impact Factor

Protective effects of 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors on oxidative modification of human low density lipoproteins in vitro.

Clin Hemorheol Microcirc 2016 ;61(4):615-32

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department Radiopharmaceutical and Chemical Biology, Dresden, Germany.

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http://dx.doi.org/10.3233/CH-141923DOI Listing
January 2017
6 Reads
2.242 Impact Factor

The why and how of amino acid analytics in cancer diagnostics and therapy.

J Biotechnol 2017 Jan 5;242:30-54. Epub 2016 Dec 5.

OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany; CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2016.12.001DOI Listing
January 2017
47 Reads
2.871 Impact Factor

Multimodal Somatostatin Receptor Theranostics Using [(64)Cu]Cu-/[(177)Lu]Lu-DOTA-(Tyr(3))octreotate and AN-238 in a Mouse Pheochromocytoma Model.

Theranostics 2016 10;6(5):650-65. Epub 2016 Mar 10.

7. Paul Langerhans Institute Dresden of the Helmholtz Center Munich at the University Hospital and faculty of Medicine, Technische Universität Dresden, Dresden, Germany;; 8. German Center for Diabetes Research e.V., Neuherberg, Germany.

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http://dx.doi.org/10.7150/thno.14479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805660PMC
December 2016
41 Reads
7.827 Impact Factor

Extracellular S100A4 affects endothelial cell integrity and stimulates transmigration of A375 melanoma cells.

Biochem Biophys Res Commun 2016 09 4;477(4):963-969. Epub 2016 Jul 4.

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department Radiopharmaceutical and Chemical Biology, Dresden, Germany; Technische Universität Dresden, Department of Chemistry and Food Chemistry, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.07.009DOI Listing
September 2016
11 Reads
2.297 Impact Factor

Synthesis and Kinetic Characterisation of Water-Soluble Fluorogenic Acyl Donors for Transglutaminase 2.

Chembiochem 2016 07 30;17(13):1263-81. Epub 2016 May 30.

Helmholtz-Zentrum Dresden-Rossendorf, Institut für Radiopharmazeutische Krebsforschung, Bautzner Landstrasse 400, 01328, Dresden, Germany.

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http://doi.wiley.com/10.1002/cbic.201600048
Publisher Site
http://dx.doi.org/10.1002/cbic.201600048DOI Listing
July 2016
8 Reads
3.088 Impact Factor

Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Therapy-A Hypothesis-Driven Review.

Antioxidants (Basel) 2016 Apr 19;5(2). Epub 2016 Apr 19.

Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstrasse 400, Dresden D-01328, Germany.

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http://dx.doi.org/10.3390/antiox5020014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931535PMC
April 2016
5 Reads

Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats.

BMC Anesthesiol 2015 18;15:36. Epub 2015 Mar 18.

Department of Anesthesia and Intensive Care, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1186/s12871-015-0013-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372178PMC
March 2016
12 Reads
1.333 Impact Factor

Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET radiotracers.

Bioorg Med Chem 2015 Sep 2;23(17):6025-35. Epub 2015 Jul 2.

Helmholtz-Zentrum Dresden-Rossendorf, Institut für Radiopharmazeutische Krebsforschung, Bautzner Landstraße 400, D-01328 Dresden, Germany; TU Dresden, Fachbereich Chemie und Lebensmittelchemie, D-01062 Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.06.040DOI Listing
September 2015
12 Reads
2.793 Impact Factor

Novel (pyrazolyl)benzenesulfonamides with a nitric oxide-releasing moiety as selective cyclooxygenase-2 inhibitors.

Bioorg Med Chem Lett 2015 Aug 29;25(16):3295-300. Epub 2015 May 29.

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department Radiopharmaceutical and Chemical Biology, Bautzner Landstrasse 400, 01328 Dresden, Germany; Technische Universität Dresden, Department of Chemistry and Food Chemistry, 01069 Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.05.059DOI Listing
August 2015
6 Reads
2.420 Impact Factor

Organotypical vascular model for characterization of radioprotective compounds: studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors.

Clin Hemorheol Microcirc 2014 ;58(1):281-95

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden- Rossendorf, Dresden, Germany Department of Chemistry and Food Chemistry, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.3233/CH-141902DOI Listing
July 2015
4 Reads
2.242 Impact Factor

Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes.

Front Chem 2015 23;3:37. Epub 2015 Jun 23.

Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf Dresden, Germany ; Department of Chemistry and Food Chemistry, Technische Universität Dresden Dresden, Germany.

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http://dx.doi.org/10.3389/fchem.2015.00037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477214PMC
July 2015
2 Reads

(18)F-Labeled 1,4-Dioxa-8-azaspiro[4.5]decane Derivative: Synthesis and Biological Evaluation of a σ1 Receptor Radioligand with Low Lipophilicity as Potent Tumor Imaging Agent.

J Med Chem 2015 Jul 2;58(14):5395-407. Epub 2015 Jul 2.

‡Key Laboratory of Radiopharmaceuticals (Beijing Normal University), Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.

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http://dx.doi.org/10.1021/acs.jmedchem.5b00593DOI Listing
July 2015
22 Reads
5.447 Impact Factor

Effects of pulmonary acid aspiration on the regional pulmonary blood flow within the first hour after injury: An observational study in rats.

Clin Hemorheol Microcirc 2015 Jul;60(2):253-62

Department of Anesthesia and Intensive Care, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.3233/CH-141867DOI Listing
July 2015
20 Reads
2.242 Impact Factor

Diaryl-Substituted (Dihydro)pyrrolo[3,2,1-hi]indoles, a Class of Potent COX-2 Inhibitors with Tricyclic Core Structure.

J Org Chem 2015 Jun 13;80(11):5611-24. Epub 2015 May 13.

†Helmholtz-Zentrum Dresden-Rossendorf, Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.

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http://dx.doi.org/10.1021/acs.joc.5b00537DOI Listing
June 2015
3 Reads
4.721 Impact Factor

Synthesis and biodistribution studies of (3)H- and (64)Cu-labeled dendritic polyglycerol and dendritic polyglycerol sulfate.

Bioconjug Chem 2015 May 11;26(5):906-18. Epub 2015 May 11.

‡Organische Chemie, Institut für Chemie und Biochemie, Freie Universität Berlin, Takustrasse 3, D-14195, Berlin, Germany.

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http://dx.doi.org/10.1021/acs.bioconjchem.5b00127DOI Listing
May 2015
44 Reads
4.513 Impact Factor

Optical imaging of COX-2: studies on an autofluorescent 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitor.

Biochem Biophys Res Commun 2015 Feb 27;458(1):40-5. Epub 2015 Jan 27.

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Radiopharmaceutical and Chemical Biology, Dresden, Germany; Technische Universität Dresden, Department of Chemistry and Food Chemistry, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.01.057DOI Listing
February 2015
17 Reads
2.297 Impact Factor

Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis.

Org Biomol Chem 2015 Feb;13(6):1878-96

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstraße 400, 01328 Dresden, Germany.

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http://dx.doi.org/10.1039/c4ob02348jDOI Listing
February 2015
32 Reads
3.562 Impact Factor

Biocompatibility and inflammatory response in vitro and in vivo to gelatin-based biomaterials with tailorable elastic properties.

Biomaterials 2014 Dec 5;35(37):9755-9766. Epub 2014 Sep 5.

Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Radiopharmaceutical and Chemical Biology, Dresden, Germany; Technische Universität Dresden, Department of Chemistry and Food Chemistry, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.08.023DOI Listing
December 2014
15 Reads
8.557 Impact Factor

In vivo fluorescence imaging and urinary monoamines as surrogate biomarkers of disease progression in a mouse model of pheochromocytoma.

Endocrinology 2014 Nov 19;155(11):4149-56. Epub 2014 Aug 19.

Department of Radiopharmaceutical and Chemical Biology (M.U., R.B., J.P.), Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany; Department of Medicine III (M.U., N.Q., M.E.-B., G.E., S.R.B., C.G.Z.), University Hospital Carl Gustav Carus, 01307 Dresden, Germany; Institute for Clinical Chemistry and Laboratory Medicine (M.P., N.Q., G.E.), Technische Universität Dresden, Germany; Department of Radioimmunology (M.C.), Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, 01328 Dresden, Germany; Department of Chemistry and Food Chemistry (J.P.), Technische Universität Dresden, Dresden, Germany; and VA Medical Center Miami FL and Department of Pathology and Medicine (N.L.B., A.V.S.), Division of Endocrinology and Hematology-Oncology, University of Miami Miller School of Medicine, Miami, Florida 33136.

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http://dx.doi.org/10.1210/en.2014-1431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256828PMC
November 2014
34 Reads
4.503 Impact Factor

Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2.

J Labelled Comp Radiopharm 2014 Sep 29;57(11):660-5. Epub 2014 Sep 29.

Institut für Radiopharmazeutische Krebsforschung, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstraße 400, D-01328, Dresden, Germany; Fachbereich Chemie und Lebensmittelchemie, Technische Universität Dresden, D-01062, Dresden, Germany.

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http://dx.doi.org/10.1002/jlcr.3237DOI Listing
September 2014
33 Reads
1.187 Impact Factor

Synthesis and radiopharmacological evaluation of ⁶⁴Cu-labeled bombesin analogs featuring a bis(2-pyridylmethyl)-1,4,7-triazacyclononane chelator.

Eur J Med Chem 2013 12;70:434-46. Epub 2013 Oct 12.

Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, P.O. Box 510119, 01314 Dresden, Germany.

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http://dx.doi.org/10.1016/j.ejmech.2013.10.013DOI Listing
September 2014
2 Reads
3.447 Impact Factor

Bispidine dioxotetraaza macrocycles: a new class of bispidines for (64)Cu PET imaging.

Inorg Chem 2014 Jul 6;53(13):6698-707. Epub 2014 Jun 6.

Anorganisch-Chemisches Institut, Universität Heidelberg , INF 270, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1021/ic500476uDOI Listing
July 2014
11 Reads
4.762 Impact Factor

Radiolabeled Cetuximab Conjugates for EGFR Targeted Cancer Diagnostics and Therapy.

Pharmaceuticals (Basel) 2014 Mar 5;7(3):311-38. Epub 2014 Mar 5.

Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, Dresden 01328, Germany.

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http://dx.doi.org/10.3390/ph7030311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978494PMC
March 2014
1 Read

Metastatic potential of B16-F10 melanoma cells is enhanced by extracellular S100A4 derived from RAW264.7 macrophages.

Biochem Biophys Res Commun 2014 Mar 5;446(1):143-8. Epub 2014 Mar 5.

Department Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany; Department of Chemistry and Food Chemistry, Technische Universität Dresden, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.02.126DOI Listing
March 2014
116 Reads
2.297 Impact Factor

Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential.

Radiother Oncol 2014 Feb 16;110(2):362-9. Epub 2014 Jan 16.

Department of Radiation Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany; OncoRay-National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany; Institute of Radiation Oncology, Helmholtz-Zentrum Dresden - Rossendorf, Germany; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2013.12.001DOI Listing
February 2014
23 Reads
4.363 Impact Factor

Tissue transglutaminase: an emerging target for therapy and imaging.

Bioorg Med Chem Lett 2013 Dec;23(24):6528-43

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http://dx.doi.org/10.1016/j.bmcl.2013.09.060DOI Listing
December 2013
11 Reads
2.420 Impact Factor

Pulmonary blood flow increases in damaged regions directly after acid aspiration in rats.

Anesthesiology 2013 Oct;119(4):890-900

* Staff Anesthetist, # Professor and Head of the Intensive Care Unit, ** Professor and Chair of the Department, Department of Anesthesia and Intensive Care, Carl Gustav Carus University Hospital, University of Technology, Dresden, Germany. † Senior Scientist, ‖ Professor, Head of the Division of Radiopharmaceutical Biology, Institute of Radiopharmacy, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany. ‡ Senior Scientist, § Professor, Head of the Institute of Anatomy, University of Technology.

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http://dx.doi.org/10.1097/ALN.0b013e3182a17e5bDOI Listing
October 2013
6 Reads
5.879 Impact Factor

Synthesis and radiopharmacological characterisation of a fluorine-18-labelled azadipeptide nitrile as a potential PET tracer for in vivo imaging of cysteine cathepsins.

ChemMedChem 2013 Aug 19;8(8):1330-44. Epub 2013 Jun 19.

Institut für Radiopharmazeutische Krebsforschung, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstraße 400, 01328 Dresden, Germany.

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http://dx.doi.org/10.1002/cmdc.201300135DOI Listing
August 2013
22 Reads
2.968 Impact Factor

[Not Available].

J Oncol 2009 17;2009:106378. Epub 2009 Jun 17.

Research Center Dresden-Rossendorf, Institute of Radiopharmacy, P.O. Box 510119, 01314 Dresden, Germany.

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http://www.hindawi.com/journals/jo/2009/106378/
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http://dx.doi.org/10.1155/2009/106378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699447PMC
July 2013
15 Reads

Optimization of pentadentate bispidines as bifunctional chelators for 64Cu positron emission tomography (PET).

Inorg Chem 2013 Jul 2;52(14):8131-43. Epub 2013 Jul 2.

Anorganisch-Chemisches Institut, Universität Heidelberg, INF 270, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1021/ic4008685DOI Listing
July 2013
17 Reads
4.762 Impact Factor

An efficient bioorthogonal strategy using CuAAC click chemistry for radiofluorinations of SNEW peptides and the role of copper depletion.

ChemMedChem 2013 Jun 4;8(6):935-45. Epub 2013 Apr 4.

Institut für Radiopharmazeutische Krebsforschung, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1002/cmdc.201300053DOI Listing
June 2013
12 Reads
2.968 Impact Factor

Copper(II) chemistry of the functionalized macrocycle cyclam tetrapropionic acid.

Dalton Trans 2013 May 7;42(17):6142-8. Epub 2012 Dec 7.

Universität Heidelberg, Anorganisch-Chemisches Institut, INF 270, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1039/c2dt32356gDOI Listing
May 2013
21 Reads
4.197 Impact Factor

Radiolabeled COX-2 inhibitors for non-invasive visualization of COX-2 expression and activity--a critical update.

Molecules 2013 May 29;18(6):6311-55. Epub 2013 May 29.

Department Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstrasse 400, 01328 Dresden, Germany.

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http://dx.doi.org/10.3390/molecules18066311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269837PMC
May 2013
24 Reads
2.416 Impact Factor

Anti-tumor effects of peptide analogs targeting neuropeptide hormone receptors on mouse pheochromocytoma cells.

Mol Cell Endocrinol 2013 May 23;371(1-2):189-94. Epub 2012 Dec 23.

University Hospital Carl Gustav Carus, Department of Medicine III, Dresden, Germany.

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http://dx.doi.org/10.1016/j.mce.2012.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690370PMC
May 2013
4.405 Impact Factor

Experimental hypoxia does not influence gene expression and protein synthesis of Eph receptors and ephrin ligands in human melanoma cells in vitro.

Melanoma Res 2013 Apr;23(2):85-95

Department of Radiopharmaceutical and Chemical Biology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1097/CMR.0b013e32835e58f3DOI Listing
April 2013
8 Reads
2.282 Impact Factor

2-Carbaborane-3-phenyl-1H-indoles--synthesis via McMurry reaction and cyclooxygenase (COX) inhibition activity.

ChemMedChem 2013 Feb 9;8(2):329-35. Epub 2013 Jan 9.

Institut für Radiopharmazie, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstrasse 400, 01328 Dresden, Germany.

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http://dx.doi.org/10.1002/cmdc.201200455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849512PMC
February 2013
5 Reads
2.968 Impact Factor

Visualization of cyclooxygenase-2 using a 2,3-diarylsubstituted indole-based inhibitor and confocal laser induced cryofluorescence microscopy at 20K in melanoma cells in vitro.

Biochem Biophys Res Commun 2013 Jan 9;430(1):301-6. Epub 2012 Nov 9.

Institute of Radiopharmacy (From January 2013 Institute of Radiopharmaceutical Cancer Research), Helmholtz-Zentrum Dresden-Rossendorf, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1202141
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http://dx.doi.org/10.1016/j.bbrc.2012.10.133DOI Listing
January 2013
22 Reads
2.297 Impact Factor

Protein and non-protein biomarkers in melanoma: a critical update.

Amino Acids 2012 Dec 6;43(6):2203-30. Epub 2012 Oct 6.

Department of Radiopharmaceutical Biology, Institute of Radiopharmacy, Helmholtz-Zentrum Dresden-Rossendorf, POB 510119, 01314, Dresden, Germany.

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http://link.springer.com/content/pdf/10.1007%2Fs00726-012-14
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http://link.springer.com/10.1007/s00726-012-1409-5
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http://dx.doi.org/10.1007/s00726-012-1409-5DOI Listing
December 2012
15 Reads
3.293 Impact Factor

(18)F-Labeled phosphopeptide-cell-penetrating peptide dimers with enhanced cell uptake properties in human cancer cells.

Nucl Med Biol 2012 Nov 10;39(8):1202-12. Epub 2012 Jul 10.

Institute of Radiopharmacy, Helmholtz Centre Dresden-Rossendorf, 01314 Dresden, Germany.

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http://dx.doi.org/10.1016/j.nucmedbio.2012.06.003DOI Listing
November 2012
21 Reads
2.412 Impact Factor

Irradiation affects cellular properties and Eph receptor expression in human melanoma cells.

Cell Adh Migr 2012 Mar-Apr;6(2):113-25. Epub 2012 Mar 1.

Department of Radiopharmaceutical Biology, Institute of Radiopharmacy, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.4161/cam.20655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499310PMC
November 2012
3 Reads
4.505 Impact Factor

Site-selective radiolabeling of peptides by (18)F-fluorobenzoylation with [(18F)]SFB in solution and on solid phase: a comparative study.

Amino Acids 2012 Oct;43(4):1431-43

Institut für Radiopharmazie, Helmholtz-Zentrum Dresden-Rossendorf, Bautzner Landstrasse 400, 01328 Dresden, Germany.

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http://link.springer.com/10.1007/s00726-012-1216-z
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October 2012
2 Reads
3.293 Impact Factor

Radiosynthesis of a ¹⁸F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo.

Bioorg Med Chem 2012 Jun 17;20(11):3410-21. Epub 2012 Apr 17.

Institute of Radiopharmacy, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1016/j.bmc.2012.04.022DOI Listing
June 2012
66 Reads
2.793 Impact Factor

Design, evaluation, and comparison of ghrelin receptor agonists and inverse agonists as suitable radiotracers for PET imaging.

Bioconjug Chem 2012 Apr 20;23(4):771-84. Epub 2012 Mar 20.

Institute of Biochemistry, Universität Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1021/bc2005889DOI Listing
April 2012
6 Reads
4.513 Impact Factor

S100 proteins in health and disease.

Authors:
Jens Pietzsch

Amino Acids 2011 Oct 1;41(4):755-60. Epub 2010 Dec 1.

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http://dx.doi.org/10.1007/s00726-010-0816-8DOI Listing
October 2011
1 Read
3.293 Impact Factor

Expression, purification and fluorine-18 radiolabeling of recombinant S100A4: a potential probe for molecular imaging of receptor for advanced glycation endproducts in vivo?

Amino Acids 2011 Oct 14;41(4):809-20. Epub 2010 Dec 14.

Department of Radiopharmaceutical Biology, Institute of Radiopharmacy, Research Center Dresden-Rossendorf, POB 51 01 19, 01314, Dresden, Germany.

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http://link.springer.com/10.1007/s00726-010-0822-x
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October 2011
6 Reads
3.293 Impact Factor

Automated radiosynthesis of the thiol-reactive labeling agent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide ([18F]FBAM).

Appl Radiat Isot 2011 Sep 8;69(9):1226-30. Epub 2011 Apr 8.

Institute of Radiopharmacy, Forschungszentrum Dresden-Rossendorf e.V., Germany.

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http://dx.doi.org/10.1016/j.apradiso.2011.03.043DOI Listing
September 2011
2 Reads
1.056 Impact Factor

Phosphopeptides with improved cellular uptake properties as ligands for the polo-box domain of polo-like kinase 1.

Bioorg Med Chem Lett 2011 Aug 30;21(16):4686-9. Epub 2011 Jun 30.

Institute of Radiopharmacy, Helmholtz Center Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1016/j.bmcl.2011.06.103DOI Listing
August 2011
8 Reads
2.420 Impact Factor

Eph receptors and ephrin ligands: important players in angiogenesis and tumor angiogenesis.

J Oncol 2010 10;2010:135285. Epub 2010 Mar 10.

Department of Radiopharmaceutical Biology, Institute of Radiopharmacy, Research Center Dresden-Rossendorf, 01328 Dresden, Germany.

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http://dx.doi.org/10.1155/2010/135285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836134PMC
July 2011
23 Reads

A novel tetrabranched neurotensin(8-13) cyclam derivative: synthesis, 64Cu-labeling and biological evaluation.

J Inorg Biochem 2011 Jun 22;105(6):821-32. Epub 2011 Mar 22.

Institute of Radiopharmacy, Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1016/j.jinorgbio.2011.02.011DOI Listing
June 2011
1 Read
3.444 Impact Factor

Synthesis and evaluation of 1,5-diaryl-substituted tetrazoles as novel selective cyclooxygenase-2 (COX-2) inhibitors.

Bioorg Med Chem Lett 2011 Mar 21;21(6):1823-6. Epub 2011 Jan 21.

Department of Oncology, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1016/j.bmcl.2011.01.057DOI Listing
March 2011
2 Reads
2.420 Impact Factor

Modulation of adrenal aldosterone release by oxidative modification of low-density lipoprotein.

Am J Hypertens 2010 Oct 17;23(10):1061-8. Epub 2010 Jun 17.

Department of Internal Medicine III, University of Technology Dresden, Germany.

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http://dx.doi.org/10.1038/ajh.2010.118DOI Listing
October 2010
3 Reads
2.852 Impact Factor

Synthesis of neurotensin(8-13)-phosphopeptide heterodimers via click chemistry.

Bioorg Med Chem Lett 2010 Jun 14;20(11):3306-9. Epub 2010 Apr 14.

Institute of Radiopharmacy, Forschungszentrum Dresden-Rossendorf e.V., Bautzner Landstrasse 400, 01328 Dresden, Germany.

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http://dx.doi.org/10.1016/j.bmcl.2010.04.038DOI Listing
June 2010
5 Reads
2.420 Impact Factor

Cyclin-dependent kinase 4/6 (cdk4/6) inhibitors: perspectives in cancer therapy and imaging.

Mini Rev Med Chem 2010 Jun;10(6):527-39

Department of Radiopharmaceutical Biology, Institute of Radiopharmacy, Research Center Dresden-Rossendorf, P.O.-Box 510119, 01314 Dresden, Germany.

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http://dx.doi.org/10.2174/138955710791384072DOI Listing
June 2010
7 Reads
2.903 Impact Factor

Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo.

Int J Biochem Cell Biol 2010 May 16;42(5):651-61. Epub 2009 Dec 16.

Institute of Radiopharmacy, Research Center Dresden-Rossendorf, P.O. Box 51 01 19, D-01314 Dresden, Germany.

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http://dx.doi.org/10.1016/j.biocel.2009.12.010DOI Listing
May 2010
3 Reads
4.046 Impact Factor

Improved multimodality imaging using alginate molding in xenograft tumor models.

J Magn Reson Imaging 2010 Mar;31(3):747-52

Institute of Radiopharmacy, Research Center Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1002/jmri.22090DOI Listing
March 2010
2 Reads
3.210 Impact Factor

Effects of posture on regional pulmonary blood flow in rats as measured by PET.

J Appl Physiol (1985) 2010 Feb 19;108(2):422-9. Epub 2009 Nov 19.

Department of Anesthesia and Critical Care, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

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http://www.physiology.org/doi/10.1152/japplphysiol.91257.200
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February 2010
5 Reads

Radiosynthesis and radiopharmacological evaluation of cyclin-dependent kinase 4 (Cdk4) inhibitors.

Eur J Med Chem 2010 Feb 24;45(2):727-37. Epub 2009 Nov 24.

Institute of Radiopharmacy, Research Center Dresden-Rossendorf, Dresden, Germany.

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February 2010
9 Reads
3.447 Impact Factor

Fluorine-18 labeling of phosphopeptides: a potential approach for the evaluation of phosphopeptide metabolism in vivo.

Biopolymers 2009 ;92(6):479-88

Institute of Radiopharmacy, Research Center Dresden-Rossendorf, Dresden, Germany.

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http://doi.wiley.com/10.1002/bip.21263
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February 2010
15 Reads
2.385 Impact Factor

Influence of irradiation on metabolism and metastatic potential of B16-F10 melanoma cells.

Int J Radiat Biol 2009 Nov;85(11):1002-12

Department of Radiopharmaceutical Biology, Forschungszentrum Dresden-Rossendorf, Institute of Radiopharmacy, Dresden, Germany.

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http://dx.doi.org/10.3109/09553000903258871DOI Listing
November 2009
15 Reads
1.837 Impact Factor

Reduction of arteriosclerotic nanoplaque formation and size by n-3 fatty acids in patients after valvular defect operation.

Forsch Komplementmed 2009 Aug 13;16(4):237-45. Epub 2009 Aug 13.

Institute of Physiology, Charité, Campus Benjamin Franklin, Berlin, Germany.

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http://dx.doi.org/10.1159/000229786DOI Listing
August 2009
5 Reads

Human S100A12: a novel key player in inflammation?

Amino Acids 2009 Mar 29;36(3):381-9. Epub 2008 Apr 29.

Department of Radiopharmaceutical Biology, Institute of Radiopharmacy, Research Center Dresden-Rossendorf, POB 51 01 19, 01314 Dresden, Germany.

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http://link.springer.com/10.1007/s00726-008-0097-7
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http://dx.doi.org/10.1007/s00726-008-0097-7DOI Listing
March 2009
6 Reads
3.293 Impact Factor

Systematic comparison of two novel, thiol-reactive prosthetic groups for 18F labeling of peptides and proteins with the acylation agent succinimidyl-4-[18F]fluorobenzoate ([18F]SFB).

Amino Acids 2009 Feb 15;36(2):283-95. Epub 2008 Apr 15.

Research Center Dresden-Rossendorf, Institute for Radiopharmacy, PF 510 119, 01314 Dresden, Germany.

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http://dx.doi.org/10.1007/s00726-008-0065-2DOI Listing
February 2009
19 Reads
3.293 Impact Factor

Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives.

Bioorg Med Chem 2009 Feb 24;17(3):1146-51. Epub 2008 Dec 24.

Department of Oncology, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1016/j.bmc.2008.12.032DOI Listing
February 2009
37 Reads
2.793 Impact Factor

Radiosynthesis and radiopharmacological evaluation of [N-methyl-11C]Org 34850 as a glucocorticoid receptor (GR)-binding radiotracer.

Appl Radiat Isot 2009 Feb 8;67(2):308-12. Epub 2008 Nov 8.

Institut für Radiopharmazie, Forschungszentrum Dresden-Rossendorf e.V., POB 51 01 19, D-01314 Dresden, Germany.

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http://dx.doi.org/10.1016/j.apradiso.2008.10.014DOI Listing
February 2009
13 Reads
1.056 Impact Factor

Prediabetic and diabetic in vivo modification of circulating low-density lipoprotein attenuates its stimulatory effect on adrenal aldosterone and cortisol secretion.

J Endocrinol 2009 Jan 3;200(1):45-52. Epub 2008 Oct 3.

Department of Internal Medicine 3, Pathological Biochemistry, Carl Gustav Carus Medical School, University of Technology Dresden, Dresden, Germany.

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http://dx.doi.org/10.1677/JOE-08-0293DOI Listing
January 2009
7 Reads
3.718 Impact Factor

Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor.

Bioorg Med Chem 2008 Aug 10;16(16):7662-70. Epub 2008 Jul 10.

Institute of Radiopharmacy, Research Center Dresden-Rossendorf, PO Box 510119, 01314 Dresden, Germany.

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http://dx.doi.org/10.1016/j.bmc.2008.07.016DOI Listing
August 2008
2.793 Impact Factor

Radiolabeled glucocorticoids as molecular probes for imaging brain glucocorticoid receptors by means of positron emission tomography (PET).

Mini Rev Med Chem 2008 Jun;8(7):728-39

Institute of Radiopharmacy, Research Center Dresden-Rossendorf, D-01314 Dresden, Germany.

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http://dx.doi.org/10.2174/138955708784567403DOI Listing
June 2008
3 Reads
2.903 Impact Factor

Synthesis and application of [18F]FDG-maleimidehexyloxime ([18F]FDG-MHO): a [18F]FDG-based prosthetic group for the chemoselective 18F-labeling of peptides and proteins.

Bioconjug Chem 2008 Jun 16;19(6):1202-10. Epub 2008 May 16.

Research Center Dresden-Rossendorf, Institute for Radiopharmacy, PF 510 119, D-01314 Dresden, Germany.

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http://dx.doi.org/10.1021/bc8000112DOI Listing
June 2008
76 Reads
4.513 Impact Factor

Yttrium-86-labelled human serum albumin microspheres: relation of surface structure with in vivo stability.

Nucl Med Biol 2008 Feb 20;35(2):227-32. Epub 2007 Dec 20.

ROTOP Pharmaka AG, Bautzner Landstrasse 45, 01454 Radeberg, Germany.

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http://dx.doi.org/10.1016/j.nucmedbio.2007.10.008DOI Listing
February 2008
9 Reads
2.412 Impact Factor

Localized proton magnetic resonance spectroscopy of lipids in adipose tissue at high spatial resolution in mice in vivo.

J Lipid Res 2008 Feb 16;49(2):473-80. Epub 2007 Nov 16.

Institute of Radiopharmacy, Research Center Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1194/jlr.D700024-JLR200DOI Listing
February 2008
12 Reads
4.421 Impact Factor

Expression, purification and fluorine-18 radiolabeling of recombinant S100 proteins--potential probes for molecular imaging of receptor for advanced glycation endproducts (RAGE) in vivo.

Protein Expr Purif 2008 Feb 22;57(2):143-52. Epub 2007 Oct 22.

Department of Radiopharmaceutical Biology, Institute of Radiopharmacy, Research Center Dresden-Rossendorf, 01314 Dresden, Germany.

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http://dx.doi.org/10.1016/j.pep.2007.10.009DOI Listing
February 2008
45 Reads
1.695 Impact Factor

L-type amino acid transporters LAT1 and LAT4 in cancer: uptake of 3-O-methyl-6-18F-fluoro-L-dopa in human adenocarcinoma and squamous cell carcinoma in vitro and in vivo.

J Nucl Med 2007 Dec;48(12):2063-71

Department of Radiopharmaceutical Biology, Institute of Radiopharmacy, Research Center Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.2967/jnumed.107.043620DOI Listing
December 2007
2 Reads
6.160 Impact Factor

Factors influencing the formation of small dense low-density lipoprotein particles in dependence on the presence of the metabolic syndrome and on the degree of glucose intolerance.

Int J Clin Pract 2007 Nov;61(11):1798-804

Medizinische Klinik und Poliklinik III, Universitätsklinikum Dresden, Dresden, Germany.

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http://dx.doi.org/10.1111/j.1742-1241.2007.01507.xDOI Listing
November 2007
2.566 Impact Factor

Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues.

Nucl Med Commun 2007 Aug;28(8):637-45

Department of Anesthesiology, Medical Faculty, Technical University Dresden, Dresden, Germany.

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http://dx.doi.org/10.1097/MNM.0b013e32822a0d9fDOI Listing
August 2007
7 Reads
1.371 Impact Factor

Experimental hypoxia is a potent stimulus for radiotracer uptake in vitro: comparison of different tumor cells and primary endothelial cells.

Cancer Lett 2007 Aug 2;254(1):102-10. Epub 2007 Apr 2.

Institute of Radiopharmacy, Research Center Dresden-Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1016/j.canlet.2007.02.016DOI Listing
August 2007
2 Reads
5.621 Impact Factor

Synthesis and radiopharmacological characterization of [11C]AL-438 as a nonsteroidal ligand for imaging brain glucocorticoid receptors.

Bioorg Med Chem Lett 2007 Jul 29;17(14):4035-9. Epub 2007 Apr 29.

Institut für Radiopharmazie, Forschungszentrum Dresden-Rossendorf e.V., POB 51 01 19, D-01314 Dresden, Germany.

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http://dx.doi.org/10.1016/j.bmcl.2007.04.094DOI Listing
July 2007
2 Reads
2.420 Impact Factor

Glycoxidised LDL isolated from subjects with impaired glucose tolerance increases CD36 and peroxisome proliferator-activator receptor gamma gene expression in macrophages.

Diabetologia 2007 May 23;50(5):1080-8. Epub 2007 Mar 23.

Department of Internal Medicine, Division of Pathological Biochemistry, Carl Gustav Carus Medical School, University of Technology, Fetscherstrasse 74, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1007/s00125-007-0645-9DOI Listing
May 2007
6.671 Impact Factor

Lipid transfer protein activities in subjects with impaired glucose tolerance.

Clin Chem Lab Med 2007 ;45(2):237-43

Medical Clinics and Outpatient Department III, University Hospital, Dresden, Germany.

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https://www.degruyter.com/view/j/cclm.2007.45.issue-2/cclm.2
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http://dx.doi.org/10.1515/CCLM.2007.032DOI Listing
April 2007
2 Reads
2.955 Impact Factor

Synthesis and biological evaluation of a new type of 99mtechnetium-labeled Fatty Acid for myocardial metabolism imaging.

Bioconjug Chem 2007 Jan-Feb;18(1):216-30

Institute of Radiopharmacy, Research Center Dresden-Rossendorf, PF 510119, D-01314 Dresden, Germany.

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http://dx.doi.org/10.1021/bc0601222DOI Listing
February 2007
31 Reads
4.513 Impact Factor

Labeling of low-density lipoproteins using the 18F-labeled thiol-reactive reagent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide.

Nucl Med Biol 2007 Jan 16;34(1):5-15. Epub 2006 Nov 16.

Institute of Radiopharmacy, Research Center Rossendorf, POB 51 01 19, D-01314 Dresden, Germany.

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January 2007
8 Reads
2.412 Impact Factor

Neurotensin receptors in adeno- and squamous cell carcinoma.

Anticancer Res 2006 Sep-Oct;26(5A):3527-33

Department of Radiopharmaceutical Biology, Institute of Radiopharmacy, Research Center Rossendorf, POB 51 01 19, 01314 Dresden, Germany.

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November 2006
1.872 Impact Factor

Biodistribution and catabolism of 18F-labeled N-epsilon-fructoselysine as a model of Amadori products.

Nucl Med Biol 2006 Oct;33(7):865-73

Institute of Radiopharmacy, Research Center Rossendorf, P.O. Box 51 01 19, D-01314 Dresden, Germany.

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http://dx.doi.org/10.1016/j.nucmedbio.2006.07.007DOI Listing
October 2006
110 Reads
2.412 Impact Factor

Glucose-induced enhancement of hemin-catalyzed LDL oxidation in vitro and in vivo.

Authors:
U Julius J Pietzsch

Antioxid Redox Signal 2005 Nov-Dec;7(11-12):1507-12

Medical Clinic and Outpatient Department III, University Hospital Dresden, Dresden, Germany.

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http://dx.doi.org/10.1089/ars.2005.7.1507DOI Listing
March 2006
7.407 Impact Factor

Positron emission tomography in food sciences.

Amino Acids 2005 Dec;29(4):303-5

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http://dx.doi.org/10.1007/s00726-005-0198-5DOI Listing
December 2005
3.293 Impact Factor

Small animal positron emission tomography in food sciences.

Amino Acids 2005 Dec 2;29(4):355-76. Epub 2005 Sep 2.

Positron Emission Tomography Center, Institute of Bioinorganic and Radiopharmaceutical Chemistry, Research Center Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1007/s00726-005-0237-2DOI Listing
December 2005
3 Reads
3.293 Impact Factor

Biodistribution and catabolism of 18F-labelled isopeptide N(epsilon)-(gamma-glutamyl)-L-lysine.

Amino Acids 2005 Dec 31;29(4):405-13. Epub 2005 May 31.

Positron Emission Tomography Center, Institute of Bioinorganic and Radiopharmaceutical Chemistry, Research Center Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1007/s00726-005-0204-yDOI Listing
December 2005
3.293 Impact Factor

Synthesis and biodistribution of an 18F-labelled resveratrol derivative for small animal positron emission tomography.

Amino Acids 2005 Dec 8;29(4):415-28. Epub 2005 Jul 8.

Positron Emission Tomography Center, Institute of Bioinorganic and Radiopharmaceutical Chemistry, Research Center Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1007/s00726-005-0205-xDOI Listing
December 2005
2 Reads
3.293 Impact Factor

Catabolism of native and oxidized low density lipoproteins: in vivo insights from small animal positron emission tomography studies.

Amino Acids 2005 Dec 15;29(4):389-404. Epub 2005 Jul 15.

Positron Emission Tomography Center, Institute of Bioinorganic and Radiopharmaceutical Chemistry, Research Center Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1007/s00726-005-0203-zDOI Listing
December 2005
3.293 Impact Factor

3-O-methyl-6-18F-fluoro-L-dopa, a new tumor imaging agent: investigation of transport mechanism in vitro.

J Nucl Med 2004 Dec;45(12):2116-22

Institut fuer Bioanorganische und Radiopharmazeutische Chemie, PET Zentrum Rossendorf, Forschungszentrum Rossendorf, Dresden, Germany.

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December 2004
10 Reads
6.160 Impact Factor

Fluorine-18 radiolabeling of low-density lipoproteins: a potential approach for characterization and differentiation of metabolism of native and oxidized low-density lipoproteins in vivo.

Nucl Med Biol 2004 Nov;31(8):1043-50

PET-Center, Institute of Bioinorganic and Radiopharmaceutical Chemistry, Research Center Rossendorf Dresden, D-01314 Dresden, Germany.

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http://dx.doi.org/10.1016/j.nucmedbio.2004.08.009DOI Listing
November 2004
66 Reads
2.412 Impact Factor

[Oxidatively modified lipoproteins and their antibodies in patients with antiphospholipid syndromeand systemic lupus erythematosus].

Z Rheumatol 2004 Aug;63(4):331-7

Med. Klinik III, Bereich Rheumatologie, Universitätsklinikum Carl Gustav Carus, Fetscherstr. 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.1007/s00393-004-0601-8DOI Listing
August 2004
0.456 Impact Factor

Validation of different chemilumigenic substrates for detecting extracellular generation of reactive oxygen species by phagocytes and endothelial cells.

Luminescence 2003 Sep-Oct;18(5):268-73

Department of Internal Medicine 3, Carl Gustav Carus Medical School, University of Technology Dresden, Dresden, Germany.

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http://dx.doi.org/10.1002/bio.737DOI Listing
July 2004
5 Reads
1.518 Impact Factor

The protective effects of HDL and its constituents against neutrophil respiratory burst activation by hypochlorite-oxidized LDL.

Mol Cell Biochem 2004 Mar;258(1-2):121-7

Department of Internal Medicine 3, Pathological Biochemistry, Carl Gustav Carus Medical School, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1023/b:mcbi.0000012842.19059.c5DOI Listing
March 2004
3 Reads
2.393 Impact Factor

The pivotal role of scavenger receptor CD36 and phagocyte-derived oxidants in oxidized low density lipoprotein-induced adhesion to endothelial cells.

Int J Biochem Cell Biol 2004 Mar;36(3):460-71

Department of Internal Medicine 3, Carl Gustav Carus Medical School, University of Technology Dresden, Fetscherstrasse 74, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1016/j.biocel.2003.08.001DOI Listing
March 2004
3 Reads
4.046 Impact Factor

Analysis of 6-hydroxy-2-aminocaproic acid (HACA) as a specific marker of protein oxidation: the use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry.

Amino Acids 2004 Feb 21;26(1):45-51. Epub 2003 Aug 21.

Institute of Bioinorganic and Radiopharmaceutical Chemistry, Research Center Rossendorf, Dresden, Germany.

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http://dx.doi.org/10.1007/s00726-003-0036-6DOI Listing
February 2004
3.293 Impact Factor

The effect of garlic on arteriosclerotic nanoplaque formation and size.

Phytomedicine 2004 Jan;11(1):24-35

Institute of Physiology, Charité, Campus Benjamin Franklin, Berlin, Germany.

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http://dx.doi.org/10.1078/0944-7113-00377DOI Listing
January 2004
2 Reads
3.126 Impact Factor

Measurement of 5-hydroxy-2-aminovaleric acid as a specific marker of metal catalysed oxidation of proline and arginine residues of low density lipoprotein apolipoprotein B-100 in human atherosclerotic lesions.

J Clin Pathol 2003 Aug;56(8):622-3

Institute of Bioinorganic and Radiopharmaceutical Chemistry, Research Center Rossendorf, PO Box 510119, D-01314 Dresden, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770034PMC
http://dx.doi.org/10.1136/jcp.56.8.622DOI Listing
August 2003
2.915 Impact Factor

Analysis of 3-chlorotyrosine as a specific marker of protein oxidation: the use of N(O,S)-ethoxycarbonyltrifluoroethyl ester derivatives and gas chromatography/mass spectrometry.

Rapid Commun Mass Spectrom 2003 ;17(8):767-70

Institute of Bioinorganic and Radiopharmaceutical Chemistry, Research Center Rossendorf Dresden, PO Box 51 01 19, 01314 Dresden, Germany.

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http://dx.doi.org/10.1002/rcm.977DOI Listing
May 2003
2 Reads
2.253 Impact Factor

Lack of association between serum paraoxonase 1 activities and increased oxidized low-density lipoprotein levels in impaired glucose tolerance and newly diagnosed diabetes mellitus.

J Clin Endocrinol Metab 2003 Apr;88(4):1711-6

Department of Internal Medicine 3, Carl Gustav Carus Medical School, University of Technology Dresden, Germany.

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http://dx.doi.org/10.1210/jc.2002-021561DOI Listing
April 2003
4 Reads
6.209 Impact Factor

Increased cholesteryl ester transfer protein activity in impaired glucose tolerance: relationship to high density lipoprotein metabolism.

Croat Med J 2003 Apr;44(2):171-7

Pathological Biochemistry Group, Department Positron Emission Tomography, Institute of Bioinorganic and Radiopharmaceutical Chemistry, Rossendorf Research Center, P.O. Box 51 01 19, D-01314 Dresden, Germany.

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April 2003
1.373 Impact Factor

Intraindividual comparison of two extracorporeal LDL apheresis methods: lipidfiltration and HELP.

Int J Artif Organs 2002 Dec;25(12):1180-8

Institute for Clinical Metabolic Research, University Hospital, Dresden, Germany.

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http://dx.doi.org/10.1177/039139880202501210DOI Listing
December 2002
1.448 Impact Factor

In vivo evidence for increased oxidation of circulating LDL in impaired glucose tolerance.

Diabetes 2002 Oct;51(10):3102-6

Department of Internal Medicine 3, Carl Gustav Carus Medical School, University of Technology Dresden, Germany.

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http://dx.doi.org/10.2337/diabetes.51.10.3102DOI Listing
October 2002
39 Reads
8.095 Impact Factor

Impaired glucose tolerance is not associated with lipid intolerance.

Diabetes Nutr Metab 2002 Apr;15(2):84-90

Centre of Clinical Studies-Metabolism and Endocrinology, Science and Technology Transfer GWT, Technial University Dresden, Germany.

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April 2002
2 Reads

UVB-induced conversion of 7-dehydrocholesterol to 1alpha,25-dihydroxyvitamin D3 in an in vitro human skin equivalent model.

J Invest Dermatol 2001 Nov;117(5):1179-85

Department of Dermatology, Carl Gustav Carus Medical School, Dresden University of Technology, Germany.

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http://dx.doi.org/10.1046/j.0022-202x.2001.01538.xDOI Listing
November 2001
7.216 Impact Factor

Homocysteine levels in patients treated with lipid apheresis: effect of a vitamin therapy.

Eur J Clin Invest 2001 Aug;31(8):667-71

Institut und Poliklinik für Klinische Stoffwechselforschung, Universitätsklinikum Dresden, Dresden, Germany.

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http://dx.doi.org/10.1046/j.1365-2362.2001.00867.xDOI Listing
August 2001
2.734 Impact Factor

Different susceptibility to oxidation of proline and arginine residues of apolipoprotein B-100 among subspecies of low density lipoproteins.

Authors:
J Pietzsch U Julius

FEBS Lett 2001 Feb;491(1-2):123-6

Institute and Policlinic of Clinical Metabolic Research, Medical Faculty Carl Gustav Carus, Technical University, Fetscherstrasse 74, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1016/s0014-5793(01)02181-0DOI Listing
February 2001
3.169 Impact Factor

Impaired glucose tolerance (IGT) is not associated with disturbed homocysteine metabolism.

Amino Acids 2000 ;18(3):289-98

Institute and Policlinic of Clinical Metabolic Research, Medical Faculty Carl Gustav Carus, Technical University Dresden, Federal Republic of Germany.

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http://dx.doi.org/10.1007/s007260050025DOI Listing
January 2001
14 Reads
3.293 Impact Factor

Oxidation of apolipoprotein B-100 in circulating LDL is related to LDL residence time. In vivo insights from stable-isotope studies.

Arterioscler Thromb Vasc Biol 2000 Oct;20(10):E63-7

Institute and Polyclinic of Clinical Metabolic Research, Technical University Dresden, Dresden, Germany.

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http://dx.doi.org/10.1161/01.atv.20.10.e63DOI Listing
October 2000
1 Read
6.000 Impact Factor

Measurement of 5-hydroxy-2-aminovaleric acid as a specific marker of iron-mediated oxidation of proline and arginine side-chain residues of low-density lipoprotein apolipoprotein B-100.

Authors:
J Pietzsch

Biochem Biophys Res Commun 2000 Apr;270(3):852-7

Institute & Policlinic of Clinical Metabolic Research, Medical Faculty "Carl Gustav Carus,", Technical University, Fetscherstrasse 74, Dresden, D-01307, Germany.

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http://dx.doi.org/10.1006/bbrc.2000.2533DOI Listing
April 2000
2.297 Impact Factor

Conversion of vitamin D3 to 1alpha,25-dihydroxyvitamin D3 in human skin equivalents.

Exp Dermatol 2000 Apr;9(2):97-103

Department of Dermatology, Carl Gustav Carus Medical School, Dresden University of Technology, Germany.

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http://dx.doi.org/10.1034/j.1600-0625.2000.009002097.xDOI Listing
April 2000
3.762 Impact Factor

Urate attenuates oxidation of native low-density lipoprotein by hypochlorite and the subsequent lipoprotein-induced respiratory burst activities of polymorphonuclear leukocytes.

Mol Cell Biochem 2000 Mar;206(1-2):51-6

Department of Internal Medicine III, Pathological Biochemistry, Carl Gustav Carus Medical School, Technical University of Dresden, Germany.

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http://dx.doi.org/10.1023/a:1007025318306DOI Listing
March 2000
2.393 Impact Factor

18 bp insertion/duplication with internal missense mutation in human hepatic lipase gene exon 3. Mutations in brief no. 181. Online.

Hum Mutat 1998 ;12(3):216

Institute of Clinical Chemistry and Laboratory Medicine, Medical Faculty Carl Gustav Carus, Technical University, Dresden, Germany.

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February 2000
5.144 Impact Factor

Metabolic basis of low high density lipoprotein in subjects with impaired glucose tolerance.

Ann N Y Acad Sci 1999 Nov;892:323-6

Institute of Clinical Metabolic Research, Medical Faculty Carl Gustav Carus, Technical University, Dresden, Germany.

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http://dx.doi.org/10.1111/j.1749-6632.1999.tb07808.xDOI Listing
November 1999
4.313 Impact Factor

Very low density lipoprotein overproduction is maximally expressed in early insulin resistant states.

Ann N Y Acad Sci 1999 Nov;892:319-22

Institute of Clinical Metabolic Research, Medical Faculty Carl Gustav Carus, Technical University, Dresden, Germany.

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http://dx.doi.org/10.1111/j.1749-6632.1999.tb07807.xDOI Listing
November 1999
4.313 Impact Factor

In vivo evidence for increased apolipoprotein A-I catabolism in subjects with impaired glucose tolerance.

Diabetes 1998 Dec;47(12):1928-34

Institute and Policlinic of Clinical Metabolic Research, Medical Faculty Carl Gustav Carus, Technical University, Dresden, Germany.

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http://dx.doi.org/10.2337/diabetes.47.12.1928DOI Listing
December 1998
4 Reads
8.095 Impact Factor

Human keratinocyte line HaCaT metabolizes 1alpha-hydroxyvitamin D3 and vitamin D3 to 1alpha,25-dihydroxyvitamin D3 (calcitriol).

J Dermatol Sci 1998 Nov;18(2):118-27

Department of Dermatology, Carl Gustav Carus Medical School, Dresden University of Technology, Germany.

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http://dx.doi.org/10.1016/s0923-1811(98)00033-4DOI Listing
November 1998
3.419 Impact Factor

Determination of total homocysteine.

Authors:
J Pietzsch A Pixa

Clin Chem 1998 Aug;44(8 Pt 1):1781-2

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August 1998
2 Reads
7.911 Impact Factor

Stable isotope ratio analysis of amino acids: the use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry.

Rapid Commun Mass Spectrom 1997 ;11(17):1835-8

Institute of Clinical Metabolic Research, Medical Faculty Carl Gustav Carus, Technical University Dresden, Germany.

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http://dx.doi.org/10.1002/(SICI)1097-0231(199711)11:17<1835::AID-RCM76>3.0.CO;2-6DOI Listing
February 1998
2.253 Impact Factor

Hypochlorite-modified low-density lipoprotein stimulates human polymorphonuclear leukocytes for enhanced production of reactive oxygen metabolites, enzyme secretion, and adhesion to endothelial cells.

Atherosclerosis 1998 Feb;136(2):315-24

Department of Internal Medicine III, Carl Gustav Carus Medical School, Technical University of Dresden, Germany.

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http://dx.doi.org/10.1016/s0021-9150(97)00233-5DOI Listing
February 1998
3.994 Impact Factor

Rapid determination of total homocysteine in human plasma by using N(O,S)-ethoxycarbonyl ethyl ester derivatives and gas chromatography-mass spectrometry.

Clin Chem 1997 Oct;43(10):2001-4

Inst. and Policlinic of Clin. Metab. Res., Med. Faculty Carl Gustav Carus, Technical Univ. Dresden, Germany.

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October 1997
7.911 Impact Factor

Increased clearance of low density lipoprotein precursors in patients with heterozygous familial defective apolipoprotein B-100: a stable isotope approach.

J Lipid Res 1996 Oct;37(10):2074-87

Institute and Policlinic of Clinical Metabolic Research, Medical Faculty "C.G. Carus', Technical University, Dresden, Germany.

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October 1996
1 Read
4.421 Impact Factor

Very fast ultracentrifugation of serum lipoproteins: influence on lipoprotein separation and composition.

Biochim Biophys Acta 1995 Jan;1254(1):77-88

Department of Clinical Metabolic Research, Medical Faculty C.G. Carus, Technical University Dresden, Germany.

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http://dx.doi.org/10.1016/0005-2760(94)00171-tDOI Listing
January 1995
1 Read

Recovery of cholesterol and triacylglycerol in very-fast ultracentrifugation of human lipoproteins in a large range of concentrations.

Eur J Clin Chem Clin Biochem 1994 Dec;32(12):929-33

Abteilung Klinische Stoffwechselforschung, Medizinische Fakultät Carl Gustav Carus, Technischen Universität Dresden, Germany.

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http://dx.doi.org/10.1515/cclm.1994.32.12.929DOI Listing
December 1994
1 Read

Very-fast ultracentrifugation of human plasma lipoproteins: influence of the centrifugal field on lipoprotein composition.

Clin Chim Acta 1994 Jan;224(1):21-32

Department of Metabolic Diseases, Medical Faculty of the Technical University, Dresden, Germany.

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http://dx.doi.org/10.1016/0009-8981(94)90117-1DOI Listing
January 1994
2.824 Impact Factor

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