Jens Peter von Kries

Jens Peter von Kries

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Jens Peter von Kries

Jens Peter von Kries

Publications by authors named "Jens Peter von Kries"

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32Publications

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Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels.

Elife 2019 Jul 18;8. Epub 2019 Jul 18.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.

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http://dx.doi.org/10.7554/eLife.49187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663466PMC
July 2019

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling.

PLoS One 2018 11;13(6):e0198492. Epub 2018 Jun 11.

Neuromuscular and Cardiovascular Cell Biology, Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198492PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995442PMC
December 2018

A Chemical Disruptor of the ClpX Chaperone Complex Attenuates the Virulence of Multidrug-Resistant Staphylococcus aureus.

Angew Chem Int Ed Engl 2017 12 12;56(49):15746-15750. Epub 2017 Oct 12.

Center for Integrated Protein Science at the Department of Chemistry, Technische Universität München, Lichtenbergstrasse 4, 85747, Garching, Germany.

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http://dx.doi.org/10.1002/anie.201708454DOI Listing
December 2017

Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach.

J Med Chem 2017 12 8;60(24):10013-10025. Epub 2017 Dec 8.

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) , Campus Berlin-Buch, 13125 Berlin, Germany.

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http://dx.doi.org/10.1021/acs.jmedchem.7b00883DOI Listing
December 2017

Identification of a Novel Benzimidazole Pyrazolone Scaffold That Inhibits KDM4 Lysine Demethylases and Reduces Proliferation of Prostate Cancer Cells.

SLAS Discov 2017 08 27;22(7):801-812. Epub 2017 Mar 27.

1 Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.

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http://dx.doi.org/10.1177/2472555217699157DOI Listing
August 2017

Substrate Hunting for the Myxobacterial CYP260A1 Revealed New 1α-Hydroxylated Products from C-19 Steroids.

Chembiochem 2016 Jan 20;17(1):90-101. Epub 2015 Nov 20.

Universität des Saarlandes, Biochemie, Campus B2.2, 66123, Saarbrücken, Germany.

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http://dx.doi.org/10.1002/cbic.201500420DOI Listing
January 2016

visualization of osteoarthritic hypertrophic lesions.

Chem Sci 2015 Nov 12;6(11):6256-6261. Epub 2015 Aug 12.

European Molecular Biology Laboratory (EMBL) , Interdisciplinary Chemistry Group , Cell Biology and Biophysics Unit , Meyerhofstr. 1 , 69117 Heidelberg , Germany . Email:

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http://dx.doi.org/10.1039/c5sc01301aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054140PMC
November 2015

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.

ChemMedChem 2015 May 15;10(5):815-26. Epub 2015 Apr 15.

Institut für Pharmazie/Institut für Chemie, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195 Berlin (Germany) http://www.bcp.fu-berlin.de/ag-rademann; Leibniz-Institut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, 13125 Berlin (Germany); Max Delbrück Center for Molecular Medicine (MDC), Robert-Rössle-Str. 10, 13125 Berlin (Germany).

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http://dx.doi.org/10.1002/cmdc.201500015DOI Listing
May 2015

Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.

Cancer Cell 2012 Dec;22(6):825-37

Research Unit Cellular Signal Integration, Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Molecular Toxicology and Pharmacology, Ingolstädter Landstrasse. 1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.ccr.2012.11.002DOI Listing
December 2012

Translocation Biosensors - Cellular System Integrators to Dissect CRM1-Dependent Nuclear Export by Chemicogenomics.

Sensors (Basel) 2009 9;9(7):5423-45. Epub 2009 Jul 9.

Department of Molecular and Cellular Oncology, University of Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany; E-Mail: (V.F.); (C.B.).

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http://dx.doi.org/10.3390/s90705423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274152PMC
September 2012

Identification of CYP106A2 as a regioselective allylic bacterial diterpene hydroxylase.

Chembiochem 2011 Mar 26;12(4):576-82. Epub 2011 Jan 26.

Universität des Saarlandes, Biochemie, Campus B2.2, 66123 Saarbrücken, Germany.

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http://dx.doi.org/10.1002/cbic.201000404DOI Listing
March 2011

Bisubstrate specificity in histidine/tryptophan biosynthesis isomerase from Mycobacterium tuberculosis by active site metamorphosis.

Proc Natl Acad Sci U S A 2011 Mar 14;108(9):3554-9. Epub 2011 Feb 14.

European Molecular Biology Laboratory, Hamburg Unit, Notkestrasse 85, D-22603 Hamburg, Germany.

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http://dx.doi.org/10.1073/pnas.1015996108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048130PMC
March 2011

Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth.

Cancer Res 2011 Jan;71(1):197-205

Section for Cellular and Genetic Therapy, Institute of Microbiology, Oslo University Hospital, and Norwegian Center for Stem Cell Research, Forskningsparken, Oslo, Norway.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1282DOI Listing
January 2011

Design of chemical libraries with potentially bioactive molecules applying a maximum common substructure concept.

Mol Divers 2010 May 15;14(2):401-8. Epub 2009 Aug 15.

FMP Leibniz Institut für Molekulare Pharmakologie, Robert-Roessle Strasse 10, 13125, Berlin, Germany.

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http://dx.doi.org/10.1007/s11030-009-9187-zDOI Listing
May 2010

Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.

Proc Natl Acad Sci U S A 2008 May 14;105(20):7275-80. Epub 2008 May 14.

Max Delbrück Center for Molecular Medicine, Robert Rössle Strasse 10, D-13125 Berlin, Germany.

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http://dx.doi.org/10.1073/pnas.0710468105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438240PMC
May 2008

The structure of human ADP-ribosylhydrolase 3 (ARH3) provides insights into the reversibility of protein ADP-ribosylation.

Proc Natl Acad Sci U S A 2006 Oct 2;103(41):15026-31. Epub 2006 Oct 2.

European Molecular Biology Laboratory Hamburg Outstation, c/o Deutsches Elektronen-Synchrotron, Institute of Immunology, University Hospital, Hamburg, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0606762103
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http://dx.doi.org/10.1073/pnas.0606762103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1622773PMC
October 2006

Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach.

Chembiochem 2005 Oct;6(10):1749-53

Max-Planck-Institut für Molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.

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http://dx.doi.org/10.1002/cbic.200500171DOI Listing
October 2005

The high-resolution Structure of LeuB (Rv2995c) from Mycobacterium tuberculosis.

J Mol Biol 2005 Feb 23;346(1):1-11. Epub 2004 Dec 23.

EMBL Hamburg Outstation, c/o DESY, Notkestr. 85, D-22603 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.jmb.2004.11.059DOI Listing
February 2005