Publications by authors named "Jens P Dreier"

100Publications

Perfusion-dependent cerebral autoregulation impairment in hemispheric stroke.

Ann Neurol 2020 Nov 20. Epub 2020 Nov 20.

Department of Neurosurgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1002/ana.25963DOI Listing
November 2020

A case of neonatal onset multisystem inflammatory disease supporting a role of interleukin-1β in moyamoya syndrome.

Neurol Neuroimmunol Neuroinflamm 2021 Jan 27;8(1):e1-3. Epub 2020 Oct 27.

From the Department of Neurology (F.W., J.P.D.), Department of Neuroradiology (C.B.), Institute of Medical Immunology (C.M.), Department of Experimental Neurology (J.P.D.), Center for Stroke Research Berlin (J.P.D.), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Bernstein Center for Computational Neuroscience Berlin (J.P.D.); and Einstein Center for Neurosciences Berlin (J.P.D.), Berlin, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000910DOI Listing
January 2021

Flavin Adenine Dinucleotide Fluorescence as an Early Marker of Mitochondrial Impairment During Brain Hypoxia.

Int J Mol Sci 2020 Jun 1;21(11). Epub 2020 Jun 1.

Institute for Neurophysiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany.

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http://dx.doi.org/10.3390/ijms21113977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312830PMC
June 2020

The role of spreading depolarizations and electrographic seizures in early injury progression of the rat photothrombosis stroke model.

J Cereb Blood Flow Metab 2020 Apr 2:271678X20915801. Epub 2020 Apr 2.

Center for Stroke Research Berlin (CSB), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1177/0271678X20915801DOI Listing
April 2020

Migraine aura, a predictor of near-death experiences in a crowdsourced study.

PeerJ 2019 4;7:e8202. Epub 2019 Dec 4.

Department of Neurology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.7717/peerj.8202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898989PMC
December 2019

Prevalence of near-death experiences in people with and without REM sleep intrusion.

PeerJ 2019 27;7:e7585. Epub 2019 Aug 27.

Department of Neuroanesthesiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.7717/peerj.7585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716500PMC
August 2019

Semiology and Mechanisms of Near-Death Experiences.

Curr Neurol Neurosci Rep 2019 07 27;19(9):62. Epub 2019 Jul 27.

Department of Neurology, Rigshospitalet, Copenhagen University Hospital, 2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s11910-019-0983-2DOI Listing
July 2019

Spreading depolarizations in the rat endothelin-1 model of focal cerebellar ischemia.

J Cereb Blood Flow Metab 2020 Jun 7;40(6):1274-1289. Epub 2019 Jul 7.

Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://journals.sagepub.com/doi/10.1177/0271678X19861604
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http://dx.doi.org/10.1177/0271678X19861604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232780PMC
June 2020

Early blood-brain barrier dysfunction predicts neurological outcome following aneurysmal subarachnoid hemorrhage.

EBioMedicine 2019 May;43:460-472

Departments of Brain & Cognitive Sciences, Physiology & Cell Biology, Faculty of Health Science, Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel; Department of Medical Neuroscience and Brain Repair Center, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.04.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558266PMC
May 2019

Correlates of Spreading Depolarization, Spreading Depression, and Negative Ultraslow Potential in Epidural Versus Subdural Electrocorticography.

Front Neurosci 2019 24;13:373. Epub 2019 Apr 24.

Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.3389/fnins.2019.00373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491820PMC
April 2019

Neurostereologic Lesion Volumes and Spreading Depolarizations in Severe Traumatic Brain Injury Patients: A Pilot Study.

Neurocrit Care 2019 06;30(3):557-568

Department of Neurosurgery, University of Cincinnati (UC) College of Medicine, and UC Gardner Neuroscience Institute, Cincinnati, OH, USA.

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http://dx.doi.org/10.1007/s12028-019-00692-wDOI Listing
June 2019

Na/K-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.

J Cereb Blood Flow Metab 2020 03 28;40(3):622-638. Epub 2019 Feb 28.

Department of Experimental Neurology, Charité-University Medicine Berlin, Berlin, Germany.

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http://dx.doi.org/10.1177/0271678X19833757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025397PMC
March 2020

Early focal brain injury after subarachnoid hemorrhage correlates with spreading depolarizations.

Neurology 2019 01 28;92(4):e326-e341. Epub 2018 Dec 28.

From the Research Laboratory for Stereology and Neuroscience, Bispebjerg-Frederiksberg Hospital (N.E., B.P.), University of Copenhagen; Departments of Clinical Physiology and Nuclear Medicine (E.R.) and Clinical Neurophysiology (M.F., M.L.), Rigshospitalet, University of Copenhagen, Denmark; Department of Neuroradiology (M.S., G.B.), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany; Center for Stroke Research Berlin (S.M., M.K.L.W., V.K., C.R., P.V., J.W., J.P.D.) and Departments of Experimental Neurology (S.M., C.R., J.P.D.), Neurology (S.M., J.P.D.), and Neurosurgery (P.V., J.W.), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health; Department of Neurosurgery (E.S., O.W.S.), University Hospital Heidelberg, Ruprecht Karls University Heidelberg; Neurosurgery Center Ludwigsburg-Heilbronn (O.W.S.), RKH Klinikum Ludwigsburg, Germany; UC Gardner Neuroscience Institute (J.A.H.) and Department of Neurosurgery (J.A.H.), University of Cincinnati (UC) College of Medicine, OH; Institute for Clinical Epidemiology and Applied Biostatistics (P.M.), University of Tübingen, Germany; Department of Neuroscience and Center for Healthy Aging, Panum Institute (M.L.), and Faculty of Health and Medical Sciences (B.P.), University of Copenhagen, Denmark; Bernstein Center for Computational Neuroscience Berlin (J.P.D.), Berlin; and Einstein Center for Neurosciences Berlin (J.P.D.), Germany.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006814DOI Listing
January 2019

A case report of delayed cortical infarction adjacent to sulcal clots after traumatic subarachnoid hemorrhage in the absence of proximal vasospasm.

BMC Neurol 2018 Dec 18;18(1):210. Epub 2018 Dec 18.

Department of Neurology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1186/s12883-018-1217-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297952PMC
December 2018

Large-conductance Ca-activated potassium channels are potently involved in the inverse neurovascular response to spreading depolarization.

Neurobiol Dis 2018 11 24;119:41-52. Epub 2018 Jul 24.

Department of Medical Physics and Informatics, Faculty of Medicine and Faculty of Science and Informatics, University of Szeged, Szeged, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.07.026DOI Listing
November 2018

The negative ultraslow potential, electrophysiological correlate of infarction in the human cortex.

Brain 2018 06;141(6):1734-1752

Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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https://academic.oup.com/brain/article/141/6/1734/4971515
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http://dx.doi.org/10.1093/brain/awy102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972557PMC
June 2018

Sleep, Preconditioning and Stroke.

Stroke 2017 12 7;48(12):3400-3407. Epub 2017 Nov 7.

From the Department of Clinical Neurosciences, Acute Neurorehabilitation Unit, University Hospital CHUV, Lausanne, Switzerland (A.P.); ZEN Department of Neurology, Bern University Hospital, Switzerland (M.P., L.F., C.L.B.); Department of Genetics and Epigenetics of Behavior, Istituto Italiano di Tecnologia, Genoa, Italy (M.P.); L. Sacco Department of Biomedical and Clinical Sciences, University of Milan, Italy (S.S.); and Department of Neurology (J.P.D.) and Department of Experimental Neurology (J.P.D.), Stroke Center, Charité University Medicine Berlin, Germany.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.117.018796
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http://dx.doi.org/10.1161/STROKEAHA.117.018796DOI Listing
December 2017

Simulation of spreading depolarization trajectories in cerebral cortex: Correlation of velocity and susceptibility in patients with aneurysmal subarachnoid hemorrhage.

Neuroimage Clin 2017 6;16:524-538. Epub 2017 Sep 6.

Center for Stroke Research, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1016/j.nicl.2017.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602748PMC
June 2018

Spreading depolarization is not an epiphenomenon but the principal mechanism of the cytotoxic edema in various gray matter structures of the brain during stroke.

Neuropharmacology 2018 05 21;134(Pt B):189-207. Epub 2017 Sep 21.

Center for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany; Experimental Neurology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1016/j.neuropharm.2017.09.027DOI Listing
May 2018

Event-Associated Oxygen Consumption Rate Increases ca. Five-Fold When Interictal Activity Transforms into Seizure-Like Events In Vitro.

Int J Mol Sci 2017 Sep 7;18(9). Epub 2017 Sep 7.

Neuroscience Research Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.

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http://dx.doi.org/10.3390/ijms18091925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618574PMC
September 2017

Real-time detection of lesion development in acute brain injury.

J Cereb Blood Flow Metab 2017 05;37(5):1550-1552

2 Department of Neurology, Department of Experimental Neurology, and Center for Stroke Research Berlin, Charité University Medicine Berlin, Berlin, Germany.

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http://dx.doi.org/10.1177/0271678X16677764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435298PMC
May 2017

Exploitation of the spreading depolarization-induced cytotoxic edema for high-resolution, 3D mapping of its heterogeneous propagation paths.

Proc Natl Acad Sci U S A 2017 02 21;114(9):2112-2114. Epub 2017 Feb 21.

Center for Stroke Research Berlin, Charité University Medicine Berlin, 10117 Berlin, Germany.

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http://dx.doi.org/10.1073/pnas.1700760114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338536PMC
February 2017

Heterogeneous propagation of spreading depolarizations in the lissencephalic and gyrencephalic brain.

J Cereb Blood Flow Metab 2017 Jul 1;37(7):2639-2643. Epub 2017 Jan 1.

4 Department of Physics, Humboldt University of Berlin, Berlin, Germany.

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http://dx.doi.org/10.1177/0271678X16689801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531357PMC
July 2017

Monitoring microvascular perfusion variations with laser speckle contrast imaging using a view-based temporal template method.

Microvasc Res 2017 05 5;111:49-59. Epub 2017 Jan 5.

Univ Angers, LARIS - Laboratoire Angevin de Recherche en Ingénierie des Systèmes, Angers, France.

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http://dx.doi.org/10.1016/j.mvr.2016.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353663PMC
May 2017

A new direction for spreading depolarization: Investigation in the fly brain.

Channels (Austin) 2017 03 22;11(2):97-98. Epub 2016 Sep 22.

a Department of Biology , Queen's University , Kingston , Canada.

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http://dx.doi.org/10.1080/19336950.2016.1239898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398573PMC
March 2017

Altered hypermetabolic response to cortical spreading depolarizations after traumatic brain injury in rats.

J Cereb Blood Flow Metab 2017 May 1;37(5):1670-1686. Epub 2016 Jan 1.

1 Inserm U1028, CNRS UMR 5292, Lyon Neuroscience Research Center, Team TIGER, Lyon, France.

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http://dx.doi.org/10.1177/0271678X16657571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435292PMC
May 2017

Is the blood-brain barrier differentially affected by different variants of migraine?

Authors:
Jens P Dreier

Brain 2016 07;139(Pt 7):1872-4

Department of Neurology, Charité Campus Mitte, University Medicine Berlin, Germany

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http://dx.doi.org/10.1093/brain/aww112DOI Listing
July 2016

Visualization of perfusion changes with laser speckle contrast imaging using the method of motion history image.

Microvasc Res 2016 09 16;107:106-9. Epub 2016 Jun 16.

Biomedical Optics Laboratory, Department of Applied Physics, Indian School of Mines, Dhanbad, 826004, Jharkhand, India.

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http://dx.doi.org/10.1016/j.mvr.2016.06.003DOI Listing
September 2016

Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.

J Cereb Blood Flow Metab 2017 05 1;37(5):1595-1625. Epub 2016 Jan 1.

23 Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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http://dx.doi.org/10.1177/0271678X16654496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435289PMC
May 2017

Complications in Aneurysmal Subarachnoid Hemorrhage Patients With and Without Subdural Electrode Strip for Electrocorticography.

J Clin Neurophysiol 2016 Jun;33(3):250-9

*Center for Stroke Research Berlin, Charité University Medicine Berlin, Berlin, Germany; Departments of †Neurology, ‡Experimental Neurology, §Neuroradiology, and ‖Neurosurgery, Charité University Medicine Berlin, Berlin, Germany; ¶Department of Neurosurgery, University of Cincinnati, College of Medicine, Cincinnati, Ohio, U.S.A.; and #Mayfield Clinic, Cincinnati, Ohio, U.S.A.

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http://dx.doi.org/10.1097/WNP.0000000000000274DOI Listing
June 2016

The Hijdra scale has significant prognostic value for the functional outcome of Fisher grade 3 patients with subarachnoid hemorrhage.

Clin Neuroradiol 2017 Sep 25;27(3):361-369. Epub 2016 Apr 25.

Department of Neuroradiology, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1007/s00062-016-0509-0DOI Listing
September 2017

A role of the sodium pump in spreading ischemia in rats.

J Cereb Blood Flow Metab 2017 May 1;37(5):1687-1705. Epub 2016 Jan 1.

1 Department of Experimental Neurology, Charité University Medicine Berlin, Berlin, Germany.

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http://dx.doi.org/10.1177/0271678X16639059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435275PMC
May 2017

The stroke-migraine depolarization continuum.

Neuron 2015 May;86(4):902-922

Department of Experimental Neurology, Charité University Medicine Berlin, 10117 Berlin, Germany; Center for Stroke Research, Charité University Medicine Berlin, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/j.neuron.2015.04.004DOI Listing
May 2015

A validation study of the use of near-infrared spectroscopy imaging in primary and secondary motor areas of the human brain.

Epilepsy Behav 2015 Aug 11;49:118-25. Epub 2015 May 11.

Center for Stroke Research Berlin, Charité University Medicine Berlin, Berlin, Germany; Department of Neurology, Charité University Medicine Berlin, Berlin, Germany; Department of Experimental Neurology, Charité University Medicine Berlin, Berlin, Germany; Berlin Neuroimaging Center, Charité University Medicine Berlin, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yebeh.2015.04.006DOI Listing
August 2015

Supply-demand mismatch transients in susceptible peri-infarct hot zones explain the origins of spreading injury depolarizations.

Neuron 2015 Mar;85(5):1117-31

Neurovascular Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13(th) Street, 6408, Charlestown, MA 02129, USA; Stroke Service and Neuroscience Intensive Care Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2015.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351476PMC
March 2015

How spreading depolarization can be the pathophysiological correlate of both migraine aura and stroke.

Acta Neurochir Suppl 2015 ;120:137-40

Center for Stroke Research Berlin, Charité University Medicine Berlin, Campus Charité Mitte, Charitéplatz 1, 10117, Berlin, Germany,

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http://dx.doi.org/10.1007/978-3-319-04981-6_23DOI Listing
March 2015

Continuous EEG monitoring in aneurysmal subarachnoid hemorrhage: a systematic review.

Neurocrit Care 2015 Jun;22(3):450-61

Department of Neurology, Rigshospitalet, Copenhagen University Hospital, 2100, Copenhagen, Denmark,

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http://dx.doi.org/10.1007/s12028-014-0068-7DOI Listing
June 2015

Spreading depression in continuous electroencephalography of brain trauma.

Ann Neurol 2014 Nov 17;76(5):681-94. Epub 2014 Sep 17.

Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH; Neurotrauma Center at University of Cincinnati Neuroscience Institute, Cincinnati, OH; Mayfield Clinic, Cincinnati, OH.

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http://dx.doi.org/10.1002/ana.24256DOI Listing
November 2014

Inverse neurovascular coupling to cortical spreading depolarizations in severe brain trauma.

Brain 2014 Nov 24;137(Pt 11):2960-72. Epub 2014 Aug 24.

1 Department of Neurosurgery, University of Cincinnati (UC), Neurotrauma Centre at UC Neuroscience Institute, UC College of Medicine, and Mayfield Clinic, Cincinnati, OH, USA.

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http://dx.doi.org/10.1093/brain/awu241DOI Listing
November 2014

Excitotoxicity and metabolic changes in association with infarct progression.

Stroke 2014 Apr 18;45(4):1183-5. Epub 2014 Mar 18.

From the Department of Neurosurgery (J.W., A.P., N.H., N.S., P.V.), Center for Stroke Research Berlin (J.W., A.P., N.H., N.S., M.S., C.D., J.P.D., P.V.), Departments of Neuroradiology (M.S.) and Neurology (C.D., J.P.D.), Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.113.004475DOI Listing
April 2014

Spreading depression triggers ictaform activity in partially disinhibited neuronal tissues.

Exp Neurol 2014 Mar 22;253:1-15. Epub 2013 Dec 22.

Institute of Physiology I, University of Münster, Münster, Germany; Department of Neurology, University of Münster, Münster, Germany; Shefa Neuroscience Research Center, Tehran, Iran; Klinik und Poliklinik für Neurochirurgie, University of Münster, Münster, Germany; Epilepsy Research Center, University of Münster, Münster, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144886130037
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http://dx.doi.org/10.1016/j.expneurol.2013.12.008DOI Listing
March 2014

Laminar infarcts in clinical routine: a prospective analysis in standard stroke unit patients.

J Neurol 2013 Aug 17;260(8):2118-23. Epub 2013 May 17.

Department of Neurology, Charite-University Medicine Berlin, Hindenburgdamm 30, 12203 Berlin, Germany.

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http://link.springer.com/10.1007/s00415-013-6948-5
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http://dx.doi.org/10.1007/s00415-013-6948-5DOI Listing
August 2013

Electrochemical failure of the brain cortex is more deleterious when it is accompanied by low perfusion.

Stroke 2013 Feb 3;44(2):490-6. Epub 2013 Jan 3.

Center for Stroke Research Berlin, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.112.660589DOI Listing
February 2013

Clusters of spreading depolarizations are associated with disturbed cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage.

Stroke 2013 Jan 6;44(1):220-3. Epub 2012 Dec 6.

University of Heidelberg, Department of Neurosurgery, Im Neuenheimer Feld 400, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.112.672352DOI Listing
January 2013

Evaluation of intracranial electrocorticography recording strips and tissue partial pressure of oxygen and temperature probes for radio-frequency-induced heating.

Acta Neurochir Suppl 2013 ;115:149-52

Department of Neuroradiology, Charite - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1007/978-3-7091-1192-5_29DOI Listing
December 2012

Is spreading depolarization characterized by an abrupt, massive release of gibbs free energy from the human brain cortex?

Neuroscientist 2013 Feb 24;19(1):25-42. Epub 2012 Jul 24.

Center for Stroke Research Berlin, Charité University Medicine Berlin, Berlin, Germany.

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http://dx.doi.org/10.1177/1073858412453340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526686PMC
February 2013

Chronically epileptic human and rat neocortex display a similar resistance against spreading depolarization in vitro.

Stroke 2011 Oct 11;42(10):2917-22. Epub 2011 Aug 11.

Institute of Neurophysiology, Center for Stroke Research Berlin, Department of Experimental Neurology, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.111.621581DOI Listing
October 2011

Spreading depolarizations have prolonged direct current shifts and are associated with poor outcome in brain trauma.

Brain 2011 May 7;134(Pt 5):1529-40. Epub 2011 Apr 7.

Department of Neurosurgery, University of Cincinnati, 260 Stetson St. Suite 2200, Cincinnati, OH 45219, USA.

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http://dx.doi.org/10.1093/brain/awr048DOI Listing
May 2011

The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease.

Authors:
Jens P Dreier

Nat Med 2011 Apr 7;17(4):439-47. Epub 2011 Apr 7.

Center for Stroke Research, Department of Experimental Neurology and Neurology, Charité University Medicine Berlin, Berlin, Germany.

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http://www.nature.com/articles/nm.2333
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http://dx.doi.org/10.1038/nm.2333DOI Listing
April 2011

Recurrent stroke due to a novel voltage sensor mutation in Cav2.1 responds to verapamil.

Stroke 2011 Feb 23;42(2):e14-7. Epub 2010 Dec 23.

Department of Neuropediatrics, Charité Universitätsmedizin Berlin, D-13353 Berlin, Germany.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.110.600023
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http://dx.doi.org/10.1161/STROKEAHA.110.600023DOI Listing
February 2011

Report of selective cortical infarcts in the primate clot model of vasospasm after subarachnoid hemorrhage.

Neurosurgery 2010 Sep;67(3):721-8; discussion 728-9

Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892-1414, USA.

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http://dx.doi.org/10.1227/01.NEU.0000378024.70848.8FDOI Listing
September 2010

Intraoperative monitoring of cerebral blood flow by laser speckle contrast analysis.

Neurosurg Focus 2009 Oct;27(4):E11

Department of Neurosurgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.3171/2009.8.FOCUS09148DOI Listing
October 2009

Preliminary evidence that ketamine inhibits spreading depolarizations in acute human brain injury.

Stroke 2009 Aug 11;40(8):e519-22. Epub 2009 Jun 11.

Department of Neurosurgery, University of Heidelberg, Im Neuenheimer Feld 400, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.109.549303DOI Listing
August 2009

Spreading depolarizations and late secondary insults after traumatic brain injury.

J Neurotrauma 2009 Nov;26(11):1857-66

UC Neuroscience Institute, Department of Neurosurgery, University of Cincinnati, Cincinnati, Ohio 45219, USA.

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http://dx.doi.org/10.1089/neu.2009.0961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865988PMC
November 2009

Recovery of slow potentials in AC-coupled electrocorticography: application to spreading depolarizations in rat and human cerebral cortex.

J Neurophysiol 2009 Oct 3;102(4):2563-75. Epub 2009 Jun 3.

Division of Psychiatry and Neuroscience, Department of Neurosurgery, Walter Reed Army Institute of Research, USA.

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http://dx.doi.org/10.1152/jn.00345.2009DOI Listing
October 2009

A fresh twist on carotid artery dissections.

Neurology 2009 May 25;72(21):1800-1. Epub 2009 Mar 25.

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http://dx.doi.org/10.1212/WNL.0b013e3181a4e476DOI Listing
May 2009

Nitric oxide modulates spreading depolarization threshold in the human and rodent cortex.

Stroke 2008 Apr 28;39(4):1292-9. Epub 2008 Feb 28.

Department of Experimental Neurology, Charité University Medicine Berlin, Berlin, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.107.500710DOI Listing
April 2008

Cortical spreading depression: an adverse but treatable factor in intensive care?

Curr Opin Crit Care 2007 Apr;13(2):126-33

King's College London, Department of Clinical Neurosciences, London, UK.

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http://dx.doi.org/10.1097/MCC.0b013e32807faffbDOI Listing
April 2007

Endothelin-1-induced spreading depression in rats is associated with a microarea of selective neuronal necrosis.

Exp Biol Med (Maywood) 2007 Feb;232(2):204-13

Department of Experimental Neurology, Charité Universitätsmedizin, Berlin, Berlin, Germany.

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February 2007

Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP.

Exp Neurol 2006 Dec 21;202(2):449-55. Epub 2006 Aug 21.

Department of Experimental Neurology, Charité-Universitätsmedizin Berlin, 10098 Berlin, Germany.

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http://dx.doi.org/10.1016/j.expneurol.2006.07.007DOI Listing
December 2006

Nitric oxide modulates calcium entry through P/Q-type calcium channels and N-methyl-d-aspartate receptors in rat cortical neurons.

Brain Res 2005 Nov 7;1063(1):9-14. Epub 2005 Nov 7.

Department of Experimental Neurology, Charité-University Medicine Berlin, Schumannstr. 20-21, 10117 Berlin, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S000689930501371
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http://dx.doi.org/10.1016/j.brainres.2005.09.048DOI Listing
November 2005

Partial antagonistic effect of adenosine on inverse coupling between spreading neuronal activation and cerebral blood flow in rats.

Neurocrit Care 2004 ;1(1):85-94

Department of Experimental Neurology, Charité, University Medicine Berlin, and Psychiatry, Wenckebach Hospital, Berlin, Germany.

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http://dx.doi.org/10.1385/NCC:1:1:85DOI Listing
January 2006