Publications by authors named "Jens M Hohlfeld"

100Publications

Repeatability of Phase-Resolved Functional Lung (PREFUL)-MRI Ventilation and Perfusion Parameters in Healthy Subjects and COPD Patients.

J Magn Reson Imaging 2020 Oct 14. Epub 2020 Oct 14.

Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/jmri.27385DOI Listing
October 2020

The Effect of a Thixotropic Nasal Gel on Nasal Symptoms and Inflammatory Biomarkers in Seasonal Allergic Rhinitis.

Int Arch Allergy Immunol 2020 7;181(5):385-394. Epub 2020 Apr 7.

Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover, Germany,

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http://dx.doi.org/10.1159/000506129DOI Listing
April 2020

Investigating short-time diffusion of hyperpolarized Xe in lung air spaces and tissue: A feasibility study in chronic obstructive pulmonary disease patients.

Magn Reson Med 2020 Oct 30;84(4):2133-2146. Epub 2020 Mar 30.

Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/mrm.28264DOI Listing
October 2020

Smokers with COPD Show a Shift in Energy and Nitrogen Metabolism at Rest and During Exercise.

Int J Chron Obstruct Pulmon Dis 2020 6;15:1-13. Epub 2020 Jan 6.

Fraunhofer ITEM, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research, Hannover, Germany.

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http://dx.doi.org/10.2147/COPD.S217474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956026PMC
January 2020

Noninvasive Monitoring of the Response of Human Lungs to Low-Dose Lipopolysaccharide Inhalation Challenge Using MRI: A Feasibility Study.

J Magn Reson Imaging 2020 06 15;51(6):1669-1676. Epub 2019 Nov 15.

Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/jmri.27000DOI Listing
June 2020

Randomized immunotherapy trial in dual-allergic patients using "active allergen placebo" as control.

Allergy 2019 08 28;74(8):1480-1489. Epub 2019 May 28.

Fraunhofer Institute for Toxicology and Experimental Medicine, Department of Respiratory Medicine, Hannover Medical School, German Center for Lung Research, Hannover, Germany.

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http://dx.doi.org/10.1111/all.13842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773203PMC
August 2019

Rating sputum cell quality in clinical trials for asthma and COPD treatment.

Int J Chron Obstruct Pulmon Dis 2019;14:195-198. Epub 2019 Jan 8.

Fraunhofer ITEM, Clinical Airway Research - Biomedical Research in End-stage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.

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http://dx.doi.org/10.2147/COPD.S188033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329344PMC
July 2019

Repeatability of Regional Lung Ventilation Quantification Using Fluorinated (F) Gas Magnetic Resonance Imaging.

Acad Radiol 2019 03 22;26(3):395-403. Epub 2018 Nov 22.

Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2018.10.021DOI Listing
March 2019

Isolated aggregates of lymphoid cells in the inner bronchial wall in asthma patients.

Cell Tissue Res 2018 Nov 5;374(2):423-425. Epub 2018 Oct 5.

Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.

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http://dx.doi.org/10.1007/s00441-018-2936-5DOI Listing
November 2018

Assessment of the Power Required for Optimal Use of Current Inhalation Devices.

J Aerosol Med Pulm Drug Deliv 2018 12 23;31(6):339-346. Epub 2018 May 23.

Mundipharma GmbH, Limburg, Germany.

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http://www.liebertpub.com/doi/10.1089/jamp.2017.1376
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http://dx.doi.org/10.1089/jamp.2017.1376DOI Listing
December 2018

Airway and systemic inflammatory responses to ultrafine carbon black particles and ozone in older healthy subjects.

J Toxicol Environ Health A 2018 25;81(13):576-588. Epub 2018 Apr 25.

c Hannover Medical School , Institute of Clinical Pharmacology , Hannover , Germany.

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https://www.tandfonline.com/doi/full/10.1080/15287394.2018.1
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http://dx.doi.org/10.1080/15287394.2018.1463331DOI Listing
August 2019

A GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: a feasibility randomized clinical trial.

Respir Res 2018 04 4;19(1):55. Epub 2018 Apr 4.

Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Centre for Lung Research (DZL), Grosshansdorf, Germany.

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http://dx.doi.org/10.1186/s12931-018-0751-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883532PMC
April 2018

Phase 1 pharmacokinetics and phase 3 efficacy of testosterone nasal gel in subjects with seasonal allergies.

Can Urol Assoc J 2018 Jul 19;12(7):E349-E356. Epub 2018 Mar 19.

Acerus Pharmaceuticals Corp, Mississauga, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.4898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118055PMC
July 2018

Comparison of quantitative regional ventilation-weighted fourier decomposition MRI with dynamic fluorinated gas washout MRI and lung function testing in COPD patients.

J Magn Reson Imaging 2018 06 21;47(6):1534-1541. Epub 2017 Nov 21.

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/jmri.25902DOI Listing
June 2018

Free-breathing Dynamic F Gas MR Imaging for Mapping of Regional Lung Ventilation in Patients with COPD.

Radiology 2018 03 3;286(3):1040-1051. Epub 2017 Oct 3.

From the Institute for Diagnostic and Interventional Radiology (M.G., T.F.K., A.V., F.W., J.V.C.), Institute of Biometry (F.L.), and Clinic of Pneumology (J.F., T.W., J.M.H.), Hannover Medical School, Carl-Neuberg Str 1, 30625 Hannover, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover, the German Center for Lung Research, Hannover, Germany (M.G., T.F.K., A.V., J.F., T.W., F.W., J.M.H., J.V.C.); and Fraunhofer Institute for Toxicology and Experimental Medicine, Clinical Airway Research, Hannover, Germany (J.M.H.).

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http://pubs.rsna.org/doi/10.1148/radiol.2017170591
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http://dx.doi.org/10.1148/radiol.2017170591DOI Listing
March 2018

Blood eosinophils predict therapeutic effects of a GATA3-specific DNAzyme in asthma patients.

J Allergy Clin Immunol 2017 08 22;140(2):625-628.e5. Epub 2017 Mar 22.

Institute of Laboratory Medicine, Philipps University Marburg, Marburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749173042
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http://dx.doi.org/10.1016/j.jaci.2017.02.024DOI Listing
August 2017

Specificity and reproducibility of nasal biomarkers in patients with allergic rhinitis after allergen challenge chamber exposure.

Ann Allergy Asthma Immunol 2017 03;118(3):290-297

Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany; German Center for Lung Research, Biomedical Research in Endstage and Obstructive Lung Research, Hannover, Germany.

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http://dx.doi.org/10.1016/j.anai.2017.01.018DOI Listing
March 2017

Tiotropium Respimat(®) Versus HandiHaler(®): Comparison of Bronchodilator Efficacy of Various Doses in Clinical Trials.

Adv Ther 2016 05 28;33(5):786-93. Epub 2016 Mar 28.

Clinical Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany.

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http://dx.doi.org/10.1007/s12325-016-0322-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882367PMC
May 2016

Efficacy and safety of a novel nasal steroid, S0597, in patients with seasonal allergic rhinitis.

Ann Allergy Asthma Immunol 2015 Oct 11;115(4):325-329.e1. Epub 2015 Aug 11.

Clinical Research Department, Sun Pharma Advanced Research Company Ltd, Mumbai, India.

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http://dx.doi.org/10.1016/j.anai.2015.07.016DOI Listing
October 2015

Constant-load exercise decreases the serum concentration of myeloperoxidase in healthy smokers and smokers with COPD.

Int J Chron Obstruct Pulmon Dis 2015 21;10:1393-402. Epub 2015 Jul 21.

Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), German Center for Lung Research (DZL, BREATH), Hannover, Germany.

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http://www.dovepress.com/constant-load-exercise-decreases-th
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http://dx.doi.org/10.2147/COPD.S83269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516189PMC
April 2016

Exacerbation of atopic dermatitis on grass pollen exposure in an environmental challenge chamber.

J Allergy Clin Immunol 2015 Jul 1;136(1):96-103.e9. Epub 2015 Jun 1.

Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany; Biomedical Research in Endstage and Obstructive Lung Research (BREATH), Member of the German Center for Lung Research, Hannover, Germany.

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http://dx.doi.org/10.1016/j.jaci.2015.04.015DOI Listing
July 2015

Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme.

N Engl J Med 2015 May 17;372(21):1987-95. Epub 2015 May 17.

From the Fraunhofer Institute for Toxicology and Experimental Medicine (N.K., J.M.H.) and the Department of Dermatology and Allergy, Hannover Medical School (J.Z., T.W.), Hannover, Pulmonary Research Institute at Lung Clinic Grosshansdorf, Grosshansdorf (A.-M.K.), Institut für klinische Forschung Pneumologie, Clinical Research Center Respiratory Medicine, Frankfurt (O.K.), Insaf Respiratory Research Institute, Wiesbaden (K.M.B.), Inamed, Gauting (D.K., W.T.), Pulmonary Department, Medical Clinic, University Hospital Mainz, Mainz (S.K., R.B.), Charité Research Organization, Berlin (S.I.), FGK Clinical Research, Munich (C.R.), Sterna Biologicals (J.B., U.H., A.T., J.R.) and Institute of Laboratory Medicine, Philipps University Marburg, a member of Universities Giessen and Marburg Lung Center (H.G., H.R.), Marburg - all in Germany; Upper Airways Research Laboratory, University Hospital Ghent, Ghent, Belgium (N.Z., C.B.); and the Division of Ear, Nose, and Throat Diseases, Clintec, Karolinska Institute, Stockholm (N.Z., C.B.).

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http://ssom.luc.edu/media/stritchschoolofmedicine/publicheal
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http://www.nejm.org/doi/abs/10.1056/NEJMoa1411776
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http://dx.doi.org/10.1056/NEJMoa1411776DOI Listing
May 2015

Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma.

J Allergy Clin Immunol 2015 Sep 2;136(3):797-800. Epub 2015 Apr 2.

Institute of Laboratory Medicine and Pathobiochemistry-Molecular Diagnostics, Medical Faculty, Philipps University Marburg, Universities of Giessen and Marburg Lung Center (UGMLC), Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.02.018DOI Listing
September 2015

Noninvasive quantification of airway inflammation following segmental allergen challenge with functional MR imaging: a proof of concept study.

Radiology 2015 Jan 8;274(1):267-75. Epub 2014 Sep 8.

From the Department of Diagnostic and Interventional Radiology (J.R., J.H., C.S., M.G., F.W., J.V.), Fraunhofer Institute for Toxicology and Experimental Medicine (C.W., C.F., F.S., N.K., J.M.H.), and Department of Pneumology (C.W., J.M.H.), Hannover Medical School, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research, OE 8220, Carl-Neuberg-Str 1, 30625 Hannover, Germany; and Department of Experimental Physics (Biophysics), University of Würzburg, Würzburg, Germany (P.J.).

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http://dx.doi.org/10.1148/radiol.14132607DOI Listing
January 2015

Phase-contrast MRI for detection of mild systemic hemodynamic response after segmental allergen challenge in asthmatic patients.

Acad Radiol 2014 Aug;21(8):994-1001

Institute of Interventional Radiology, Hannover Medical School, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research, OE 8220, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1016/j.acra.2014.03.003DOI Listing
August 2014

Characterization of exhaled particles from the human lungs in airway obstruction.

J Aerosol Med Pulm Drug Deliv 2015 Feb 10;28(1):52-8. Epub 2014 Jun 10.

1 Fraunhofer Institute for Toxicology and Experimental Medicine , Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research, 30625 Hannover, Germany .

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http://dx.doi.org/10.1089/jamp.2013.1104DOI Listing
February 2015

Identification and quantification of basophils in the airways of asthmatics following segmental allergen challenge.

Cytometry A 2014 Jul 14;85(7):580-7. Epub 2014 Apr 14.

Department of Clinical Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, D-30625, Hannover, Germany; Department of Pediatric Pneumology, Allergology, and Neonatology, Hannover Medical School, D-30625, Hannover, Germany.

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http://dx.doi.org/10.1002/cyto.a.22472DOI Listing
July 2014

Cell counting in human endobronchial biopsies--disagreement of 2D versus 3D morphometry.

PLoS One 2014 24;9(3):e92510. Epub 2014 Mar 24.

Department of Pneumology, Philipps-University Marburg, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Marburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092510PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963904PMC
January 2015

Impact of endobronchial allergen provocation on macrophage phenotype in asthmatics.

BMC Immunol 2014 Mar 10;15:12. Epub 2014 Mar 10.

Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1186/1471-2172-15-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007705PMC
March 2014

Potential prognostic value of biomarkers in lavage, sputum and serum in a five year clinical follow-up of smokers with and without COPD.

BMC Pulm Med 2014 Mar 1;14:30. Epub 2014 Mar 1.

Department of Clinical Airway Research, Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover 30625, Germany.

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http://dx.doi.org/10.1186/1471-2466-14-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021348PMC
March 2014

Surfactant and allergic airway inflammation.

Swiss Med Wkly 2013 29;143:w13818. Epub 2013 Jul 29.

Fraunhofer Institute for Experimental Medicine and Toxicology, Hannover, Germany.

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http://dx.doi.org/10.4414/smw.2013.13818DOI Listing
December 2013

Pollen starch granules in bronchial inflammation.

Ann Allergy Asthma Immunol 2012 Sep 18;109(3):208-214.e6. Epub 2012 Jul 18.

Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.

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http://dx.doi.org/10.1016/j.anai.2012.06.019DOI Listing
September 2012

Detection of air trapping in chronic obstructive pulmonary disease by low frequency ultrasound.

BMC Pulm Med 2012 Mar 16;12. Epub 2012 Mar 16.

Institute for Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany.

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http://dx.doi.org/10.1186/1471-2466-12-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359201PMC
March 2012

Anti-allergic drug testing in an environmental challenge chamber is suitable both in and out of the relevant pollen season.

Ann Allergy Asthma Immunol 2011 Apr 5;106(4):336-41. Epub 2011 Feb 5.

Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S108112061001254
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http://dx.doi.org/10.1016/j.anai.2010.12.018DOI Listing
April 2011

Breath profiles by electronic nose correlate with systemic markers but not ozone response.

Respir Med 2011 Sep 24;105(9):1352-63. Epub 2011 Mar 24.

Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1016/j.rmed.2011.03.002DOI Listing
September 2011

Surfactant protein D modulates pulmonary clearance of pollen starch granules.

Exp Lung Res 2010 Nov;36(9):522-30

Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany.

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http://dx.doi.org/10.3109/01902141003790148DOI Listing
November 2010

Independent information of nonspecific biomarkers in exhaled breath condensate.

Respiration 2010 12;80(5):401-9. Epub 2010 Aug 12.

Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-University, Ziemssenstrasse 1, Munich, Germany.

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http://dx.doi.org/10.1159/000319945DOI Listing
February 2011

Characterization of exhaled particles from the healthy human lung--a systematic analysis in relation to pulmonary function variables.

J Aerosol Med Pulm Drug Deliv 2010 Dec 25;23(6):371-9. Epub 2010 May 25.

Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany.

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http://dx.doi.org/10.1089/jamp.2009.0809DOI Listing
December 2010

Human eosinophil granulocytes do not express the enzyme arginase.

J Leukoc Biol 2010 Jun 3;87(6):1125-32. Epub 2010 Mar 3.

Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1189/jlb.1109741DOI Listing
June 2010

Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2010 Mar 10;181(5):438-45. Epub 2009 Dec 10.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.200909-1415O
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http://dx.doi.org/10.1164/rccm.200909-1415OCDOI Listing
March 2010

The effect of titanium dioxide nanoparticles on pulmonary surfactant function and ultrastructure.

Respir Res 2009 Sep 30;10:90. Epub 2009 Sep 30.

Fraunhofer Institute of Toxicology and Experimental Medicine, Division of Immunology, Allergology and Airway Research, Nikolai-Fuchs-Str, 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1186/1465-9921-10-90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765946PMC
September 2009

Interaction of nanoparticles with the pulmonary surfactant system.

Inhal Toxicol 2009 Jul;21 Suppl 1:97-103

Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany.

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http://dx.doi.org/10.1080/08958370903005744DOI Listing
July 2009

Therapeutic surfactants modulate the viability of eosinophils and induce inflammatory mediator release.

Int Arch Allergy Immunol 2009 17;149(4):333-42. Epub 2009 Mar 17.

Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany.

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https://www.karger.com/Article/FullText/205579
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http://dx.doi.org/10.1159/000205579DOI Listing
August 2009

Therapeutic use of surfactant components in allergic asthma.

Naunyn Schmiedebergs Arch Pharmacol 2009 Mar 15;379(3):217-24. Epub 2008 Oct 15.

Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany.

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http://dx.doi.org/10.1007/s00210-008-0354-zDOI Listing
March 2009

Elastase-induced lung emphysema in rats is not reduced by hematopoietic growth factors when applied preventionally.

Virchows Arch 2008 Jun 25;452(6):675-88. Epub 2008 Apr 25.

Department of Functional and Applied Anatomy, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.

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http://link.springer.com/10.1007/s00428-008-0591-z
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http://dx.doi.org/10.1007/s00428-008-0591-zDOI Listing
June 2008

Endotoxin augments myeloid dendritic cell influx into the airways in patients with allergic asthma.

Am J Respir Crit Care Med 2008 Jun 3;177(12):1307-13. Epub 2008 Apr 3.

Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs-Str. 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1164/rccm.200706-870OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427055PMC
June 2008

Roflumilast attenuates pulmonary inflammation upon segmental endotoxin challenge in healthy subjects: a randomized placebo-controlled trial.

Pulm Pharmacol Ther 2008 Aug 21;21(4):616-23. Epub 2008 Feb 21.

Department of Clinical Airway Research, Fraunhofer Institute of Toxicology and Experimental Medicine (ITEM), Nikolai-Fuchs-Street 1A, D-30625 Hannover, Germany.

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http://dx.doi.org/10.1016/j.pupt.2008.02.002DOI Listing
August 2008

Effects of exogenous surfactant instillation in clinical lung transplantation: a prospective, randomized trial.

J Thorac Cardiovasc Surg 2007 Jun;133(6):1620-5

Hannover Thoracic Transplant Program, Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.jtcvs.2006.12.057DOI Listing
June 2007

Effects of keratinocyte growth factor on intra-alveolar surfactant fixed in situ: Quantitative ultrastructural and immunoelectron microscopic analysis.

Anat Rec (Hoboken) 2007 Aug;290(8):974-80

Clinical Research Group "Chronic Airway Diseases", Clinic of Internal Medicine (Respiratory Medicine), Philipps-University Marburg, Baldingerstrasse, Marburg Germany.

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http://doi.wiley.com/10.1002/ar.20549
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http://dx.doi.org/10.1002/ar.20549DOI Listing
August 2007

[Pathomechanisms in chronic obstructive pulmonary disease (COPD)].

Med Klin (Munich) 2006 Dec;101(12):951-6

Abteilung Pneumologie, Medizinische Hochschule Hannover, Hannover, Deutschland.

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http://dx.doi.org/10.1007/s00063-006-1126-5DOI Listing
December 2006

Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers.

Environ Health Perspect 2006 Nov;114(11):1655-61

Drug Research and Medical Biotechnology, Fraunhofer Instituteof technology and Experimental Medicien, Hannover, Germany.

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https://ehp.niehs.nih.gov/doi/10.1289/ehp.8861
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665420PMC
http://dx.doi.org/10.1289/ehp.8861DOI Listing
November 2006

Regulation of GATA-3, c-maf and T-bet mRNA expression in bronchoalveolar lavage cells and bronchial biopsies after segmental allergen challenge.

Int Arch Allergy Immunol 2006 22;139(4):306-16. Epub 2006 Feb 22.

Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany.

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http://dx.doi.org/10.1159/000091602DOI Listing
June 2006

Invasive versus noninvasive measurement of allergic and cholinergic airway responsiveness in mice.

Respir Res 2005 Nov 25;6:139. Epub 2005 Nov 25.

Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs Str. 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1186/1465-9921-6-139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316879PMC
November 2005

Glutathione improves the function of porcine pulmonary grafts stored for twenty-four hours in low-potassium dextran solution.

J Thorac Cardiovasc Surg 2005 Sep;130(3):864-9

Hannover Thoracic Transplant Program, Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S002252230500806
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http://dx.doi.org/10.1016/j.jtcvs.2005.05.021DOI Listing
September 2005

Surfactant protein D decreases pollen-induced IgE-dependent mast cell degranulation.

Am J Physiol Lung Cell Mol Physiol 2005 Nov 24;289(5):L856-66. Epub 2005 Jun 24.

Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1152/ajplung.00009.2005DOI Listing
November 2005

Iloprost to improve surfactant function in porcine pulmonary grafts stored for twenty-four hours in low-potassium dextran solution.

J Thorac Cardiovasc Surg 2005 Jan;129(1):80-6

Hannover Thoracic Transplant Program, Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany.

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http://dx.doi.org/10.1016/j.jtcvs.2004.04.040DOI Listing
January 2005

Surfactant protein D increases phagocytosis and aggregation of pollen-allergen starch granules.

Am J Physiol Lung Cell Mol Physiol 2005 Apr 10;288(4):L692-8. Epub 2004 Dec 10.

Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs-Str. 1a, 30625 Hannover, Germany.

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http://dx.doi.org/10.1152/ajplung.00362.2004DOI Listing
April 2005

Influence of plasma and inflammatory proteins on the ultrastructure of exogenous surfactant.

J Electron Microsc (Tokyo) 2004 ;53(4):407-16

Centre of Anatomy, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1093/jmicro/dfh056DOI Listing
January 2005

Metal-rich ambient particles (particulate matter 2.5) cause airway inflammation in healthy subjects.

Am J Respir Crit Care Med 2004 Oct 30;170(8):898-903. Epub 2004 Jun 30.

Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, Hannover 30625, Germany.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.200403-423OC
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http://dx.doi.org/10.1164/rccm.200403-423OCDOI Listing
October 2004

Repetitive measurements of pulmonary mechanics to inhaled cholinergic challenge in spontaneously breathing mice.

J Appl Physiol (1985) 2004 Sep 30;97(3):1104-11. Epub 2004 Apr 30.

Fraunhofer Institute of Technology and Experimental Medicine, D-30625 Hannover, Germany.

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http://dx.doi.org/10.1152/japplphysiol.01182.2003DOI Listing
September 2004

Mass spectrometric analysis of surfactant metabolism in human volunteers using deuteriated choline.

Am J Respir Crit Care Med 2004 Jul 24;170(1):54-8. Epub 2004 Mar 24.

Department of Neonatology, Faculty of Medicine, Eberhard-Karls-University, Calwer Strasse 7, D-72076 Tübingen, Germany.

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July 2004

Eosinophil cationic protein alters pulmonary surfactant structure and function in asthma.

J Allergy Clin Immunol 2004 Mar;113(3):496-502

Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.jaci.2003.12.008DOI Listing
March 2004

Keratinocyte growth factor transiently alters pulmonary function in rats.

J Appl Physiol (1985) 2004 Feb 17;96(2):704-10. Epub 2003 Oct 17.

Department of Respiratory Medicine, Hannover Medical School, D-30625 Hannover, Germany.

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http://dx.doi.org/10.1152/japplphysiol.00783.2003DOI Listing
February 2004

In-situ topical cooling of lung grafts: early graft function and surfactant analysis in a porcine single lung transplant model.

Eur J Cardiothorac Surg 2003 Sep;24(3):411-9

Department of Thoracic and Cardiovascular Surgery, Klinikum Braunschweig, Braunschweig, Germany.

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September 2003