Jens Hjerling-Leffler

Jens Hjerling-Leffler

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Jens Hjerling-Leffler

Jens Hjerling-Leffler

Publications by authors named "Jens Hjerling-Leffler"

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Probabilistic cell typing enables fine mapping of closely related cell types in situ.

Nat Methods 2019 Nov 18. Epub 2019 Nov 18.

Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41592-019-0631-4DOI Listing
November 2019

Specialized cutaneous Schwann cells initiate pain sensation.

Science 2019 08;365(6454):695-699

Department of Medical Biochemistry and Biophysics, Division of Molecular Neurobiology, Karolinska Institutet, Stockholm 17177, Sweden.

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http://dx.doi.org/10.1126/science.aax6452DOI Listing
August 2019

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals.

Mol Psychiatry 2019 02 8;24(2):182-197. Epub 2018 Mar 8.

MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, SE5 8AF, UK.

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http://dx.doi.org/10.1038/s41380-018-0040-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330082PMC
February 2019

Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development.

Dev Cell 2018 08 2;46(4):504-517.e7. Epub 2018 Aug 2.

Laboratory of Molecular Neurobiology, Department Medical Biochemistry and Biophysics, Biomedicum, Karolinska Institutet, Stockholm 17177, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2018.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104814PMC
August 2018

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Authors:
Jeanne E Savage Philip R Jansen Sven Stringer Kyoko Watanabe Julien Bryois Christiaan A de Leeuw Mats Nagel Swapnil Awasthi Peter B Barr Jonathan R I Coleman Katrina L Grasby Anke R Hammerschlag Jakob A Kaminski Robert Karlsson Eva Krapohl Max Lam Marianne Nygaard Chandra A Reynolds Joey W Trampush Hannah Young Delilah Zabaneh Sara Hägg Narelle K Hansell Ida K Karlsson Sten Linnarsson Grant W Montgomery Ana B Muñoz-Manchado Erin B Quinlan Gunter Schumann Nathan G Skene Bradley T Webb Tonya White Dan E Arking Dimitrios Avramopoulos Robert M Bilder Panos Bitsios Katherine E Burdick Tyrone D Cannon Ornit Chiba-Falek Andrea Christoforou Elizabeth T Cirulli Eliza Congdon Aiden Corvin Gail Davies Ian J Deary Pamela DeRosse Dwight Dickinson Srdjan Djurovic Gary Donohoe Emily Drabant Conley Johan G Eriksson Thomas Espeseth Nelson A Freimer Stella Giakoumaki Ina Giegling Michael Gill David C Glahn Ahmad R Hariri Alex Hatzimanolis Matthew C Keller Emma Knowles Deborah Koltai Bettina Konte Jari Lahti Stephanie Le Hellard Todd Lencz David C Liewald Edythe London Astri J Lundervold Anil K Malhotra Ingrid Melle Derek Morris Anna C Need William Ollier Aarno Palotie Antony Payton Neil Pendleton Russell A Poldrack Katri Räikkönen Ivar Reinvang Panos Roussos Dan Rujescu Fred W Sabb Matthew A Scult Olav B Smeland Nikolaos Smyrnis John M Starr Vidar M Steen Nikos C Stefanis Richard E Straub Kjetil Sundet Henning Tiemeier Aristotle N Voineskos Daniel R Weinberger Elisabeth Widen Jin Yu Goncalo Abecasis Ole A Andreassen Gerome Breen Lene Christiansen Birgit Debrabant Danielle M Dick Andreas Heinz Jens Hjerling-Leffler M Arfan Ikram Kenneth S Kendler Nicholas G Martin Sarah E Medland Nancy L Pedersen Robert Plomin Tinca J C Polderman Stephan Ripke Sophie van der Sluis Patrick F Sullivan Scott I Vrieze Margaret J Wright Danielle Posthuma

Nat Genet 2018 07 25;50(7):912-919. Epub 2018 Jun 25.

Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41588-018-0152-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411041PMC
July 2018

Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics.

PLoS Biol 2018 06 18;16(6):e2006387. Epub 2018 Jun 18.

Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1371/journal.pbio.2006387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029811PMC
June 2018

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

Gastroenterology 2018 02 12;154(3):624-636. Epub 2017 Oct 12.

Division of Molecular Neurobiology, Department for Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381388PMC
February 2018

miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes.

Science 2017 06 1;356(6343):1168-1171. Epub 2017 Jun 1.

Department of Medical Biochemistry and Biophysics, Division of Molecular Neurobiology, Karolinska Institutet, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1126/science.aam7671DOI Listing
June 2017

Disentangling neural cell diversity using single-cell transcriptomics.

Nat Neurosci 2016 08;19(9):1131-41

Department of Neurology, Northwestern University, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/nn.4366DOI Listing
August 2016

BCL11B/CTIP2 is highly expressed in GABAergic interneurons of the mouse somatosensory cortex.

J Chem Neuroanat 2016 Jan 14;71:1-5. Epub 2015 Dec 14.

Division of Molecular Neurobiology, Department of Medical, Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08910618153001
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http://dx.doi.org/10.1016/j.jchemneu.2015.12.004DOI Listing
January 2016

Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq.

Science 2015 Mar 19;347(6226):1138-42. Epub 2015 Feb 19.

Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1126/science.aaa1934DOI Listing
March 2015

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing.

Nat Neurosci 2015 Jan 24;18(1):145-53. Epub 2014 Nov 24.

Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/nn.3881DOI Listing
January 2015

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens.

Neurobiol Dis 2013 Jan 24;49:118-27. Epub 2012 Aug 24.

Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 77 Stockholm, Sweden. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S096999611200293
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http://dx.doi.org/10.1016/j.nbd.2012.08.006DOI Listing
January 2013

The origin of neocortical nitric oxide synthase-expressing inhibitory neurons.

Front Neural Circuits 2012 9;6:44. Epub 2012 Jul 9.

NYU Neuroscience Institute, New York University Langone Medical Center New York, NY, USA.

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http://dx.doi.org/10.3389/fncir.2012.00044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391688PMC
October 2012

Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells.

J Physiol 2012 Feb 4;590(4):703-14. Epub 2012 Jan 4.

Division of Molecular Neurobiology, Department of Medical Biochemistry & Biophysics, Scheeles väg 1:A1, Karolinska Institutet, S-17177 Stockholm, Sweden.

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http://dx.doi.org/10.1113/jphysiol.2011.224386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381304PMC
February 2012

Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons.

Dev Neurobiol 2011 Jan;71(1):45-61

Smilow Neuroscience Program, Smilow Research Center, New York University School of Medicine, 550 First Avenue, New York, NY, 10016, USA.

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http://dx.doi.org/10.1002/dneu.20853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556905PMC
January 2011

The largest group of superficial neocortical GABAergic interneurons expresses ionotropic serotonin receptors.

J Neurosci 2010 Dec;30(50):16796-808

Smilow Neuroscience Program, Department of Physiology and Neuroscience, Smilow Research Center, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1869-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025500PMC
December 2010

En masse in vitro functional profiling of the axonal mechanosensitivity of sensory neurons.

Proc Natl Acad Sci U S A 2010 Sep 24;107(37):16336-41. Epub 2010 Aug 24.

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-17177 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.0914705107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941336PMC
September 2010

The cell-intrinsic requirement of Sox6 for cortical interneuron development.

Neuron 2009 Aug;63(4):466-81

Smilow Neuroscience Program and the Department of Cell Biology, Smilow Research Building, New York University School of Medicine, 522 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.neuron.2009.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773208PMC
August 2009

Characterization of Nkx6-2-derived neocortical interneuron lineages.

Cereb Cortex 2009 Jul 10;19 Suppl 1:i1-10. Epub 2009 Apr 10.

Neuroscience Program, Smilow Research Center, New York University, New York, NY 10016, USA.

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http://dx.doi.org/10.1093/cercor/bhp038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693535PMC
July 2009

Influence of environmental manipulation on exploratory behaviour in male BDNF knockout mice.

Behav Brain Res 2009 Feb 5;197(2):339-46. Epub 2008 Oct 5.

Alzheimer's Disease Research Center, NVS Department, Karolinska Institutet, Stockholm 141 86, Sweden.

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http://dx.doi.org/10.1016/j.bbr.2008.09.032DOI Listing
February 2009

The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes.

Neuron 2008 Sep;59(5):722-32

Smilow Neuroscience Program and the Department of Cell Biology, New York University, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.neuron.2008.07.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562525PMC
September 2008

Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.

Nature 2008 Jan 9;451(7177):460-4. Epub 2008 Jan 9.

Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1038/nature06488DOI Listing
January 2008

Emergence of functional sensory subtypes as defined by transient receptor potential channel expression.

J Neurosci 2007 Mar;27(10):2435-43

Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.5614-06.2
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http://dx.doi.org/10.1523/JNEUROSCI.5614-06.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672507PMC
March 2007

In vitro and in vivo differentiation of boundary cap neural crest stem cells into mature Schwann cells.

Exp Neurol 2006 Apr 25;198(2):438-49. Epub 2006 Jan 25.

Unit of Molecular Neurobiology-MBB, Karolinska Institutet, Scheeles vag 1 A1:2, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.expneurol.2005.12.015DOI Listing
April 2006

Increased progenitor proliferation and apoptotic cell death in the sensory lineage of mice overexpressing N-myc.

Cell Tissue Res 2006 Jan 13;323(1):81-90. Epub 2005 Aug 13.

Unit of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Scheelesv. 1, 171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00441-005-0011-5DOI Listing
January 2006

The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes.

Development 2005 Jun 4;132(11):2623-32. Epub 2005 May 4.

Unit of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://dev.biologists.org/cgi/doi/10.1242/dev.01852
Publisher Site
http://dx.doi.org/10.1242/dev.01852DOI Listing
June 2005