Jens Hillengass

Jens Hillengass

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Jens Hillengass

Publications by authors named "Jens Hillengass"

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Elotuzumab in Combination with Lenalidomide and Dexamethasone for Treatment-resistant Immunoglobulin Light Chain Amyloidosis With Multiple Myeloma.

Clin Lymphoma Myeloma Leuk 2019 Jan 5;19(1):e33-e36. Epub 2018 Sep 5.

Department of Blood and Marrow Transplant Program, Roswell Park Comprehensive Cancer Centre, Buffalo, NY.

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http://dx.doi.org/10.1016/j.clml.2018.08.021DOI Listing
January 2019

Automatic bone segmentation in whole-body CT images.

Int J Comput Assist Radiol Surg 2019 Jan 13;14(1):21-29. Epub 2018 Nov 13.

Division of Medical Image Computing, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 581, Heidelberg, Germany.

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http://link.springer.com/10.1007/s11548-018-1883-7
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http://dx.doi.org/10.1007/s11548-018-1883-7DOI Listing
January 2019

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2019 01 10;10(1):213. Epub 2019 Jan 10.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-08107-8
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http://dx.doi.org/10.1038/s41467-018-08107-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328616PMC
January 2019

Determination of Minimal Residual Disease in Multiple Myeloma: Does It Matter?

Curr Hematol Malig Rep 2019 Jan 22. Epub 2019 Jan 22.

Department of Internal Medicine, University of Nebraska Medical Center, 986840 Nebraska Medical Center, Omaha, NE, 68198, USA.

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http://dx.doi.org/10.1007/s11899-019-0497-7DOI Listing
January 2019

Cytogenetic abnormalities in monoclonal gammopathy of undetermined significance.

Leukemia 2018 Dec 6;32(12):2717-2719. Epub 2018 Jul 6.

Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41375-018-0202-1DOI Listing
December 2018

Oncogene-induced senescence: a potential breakpoint mechanism against malignant transformation in plasma cell disorders.

Leuk Lymphoma 2018 Nov 4;59(11):2660-2669. Epub 2018 Apr 4.

a Department of Internal Medicine V , University Hospital Heidelberg , Heidelberg , Germany.

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http://dx.doi.org/10.1080/10428194.2018.1443450DOI Listing
November 2018

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2018 09 13;9(1):3707. Epub 2018 Sep 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-04989-w
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http://dx.doi.org/10.1038/s41467-018-04989-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137048PMC
September 2018

Next-Generation Drugs Targeting the Cereblon Ubiquitin Ligase.

J Clin Oncol 2018 Jul 1;36(20):2101-2104. Epub 2018 May 1.

Sarah A. Holstein, University of Nebraska Medical Center, Omaha, NE; and Jens Hillengass and Philip L. McCarthy, Roswell Park Comprehensive Cancer Center, Buffalo, NY.

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http://dx.doi.org/10.1200/JCO.2018.77.9637DOI Listing
July 2018

Efficacy and tolerability of the histone deacetylase inhibitor panobinostat in clinical practice.

Hematol Oncol 2018 Feb 7;36(1):210-216. Epub 2017 Jul 7.

Department of Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/hon.2462DOI Listing
February 2018

Therapeutic monoclonal antibodies in combination with pomalidomide can overcome refractoriness to both agents in multiple myeloma: A case-based approach.

Hematol Oncol 2018 Feb 25;36(1):258-261. Epub 2017 Aug 25.

Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/hon.2473DOI Listing
February 2018

Minimal residual disease in multiple myeloma: use of magnetic resonance imaging.

Semin Hematol 2018 01 12;55(1):19-21. Epub 2018 Feb 12.

Department of Radiology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1053/j.seminhematol.2018.02.001DOI Listing
January 2018

Meeting report of the 6th Heidelberg Myeloma Workshop: current status and developments in diagnosis and therapy of multiple myeloma.

J Cancer Res Clin Oncol 2017 Dec 26;143(12):2521-2526. Epub 2017 Jun 26.

Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00432-017-2463-xDOI Listing
December 2017

Comparison of biosimilar filgrastim, originator filgrastim, and lenograstim for autologous stem cell mobilization in patients with multiple myeloma.

Transfusion 2017 10 26;57(10):2359-2365. Epub 2017 Jun 26.

Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service Baden-Württemberg-Hessen, Mannheim, Germany.

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http://dx.doi.org/10.1111/trf.14211DOI Listing
October 2017

Quantitative analysis of F-NaF dynamic PET/CT cannot differentiate malignant from benign lesions in multiple myeloma.

Am J Nucl Med Mol Imaging 2017 1;7(4):148-156. Epub 2017 Sep 1.

Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ)Heidelberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596317PMC
September 2017

Storage Duration of Autologous Stem Cell Preparations Has No Impact on Hematopoietic Recovery after Transplantation.

Biol Blood Marrow Transplant 2017 Apr 21;23(4):684-690. Epub 2016 Dec 21.

Department of Medicine V, Heidelberg University, Heidelberg, Germany; Institute of Transfusion Medicine and Immunology, German Red Cross Blood Service Baden-Württemberg-Hessen, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.12.631DOI Listing
April 2017

Potential therapeutic targets in plasma cell disorders: A flow cytometry study.

Cytometry B Clin Cytom 2017 03 3;92(2):145-152. Epub 2016 Feb 3.

Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/cyto.b.21351DOI Listing
March 2017

Dose-intensified bendamustine followed by autologous peripheral blood stem cell support in relapsed and refractory multiple myeloma with impaired bone marrow function.

Hematol Oncol 2016 Dec 18;34(4):200-207. Epub 2015 Mar 18.

Max-Eder-Group 'Experimental Therapies for Hematologic Malignancies', Department of Medicine V, Heidelberg University Hospital and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/hon.2199DOI Listing
December 2016

Baseline characteristics, chromosomal alterations, and treatment affecting prognosis of deletion 17p in newly diagnosed myeloma.

Am J Hematol 2016 Nov 3;91(11):E473-E477. Epub 2016 Sep 3.

Medizinische Klinik V, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ajh.24533DOI Listing
November 2016

Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes.

Blood 2016 09 25;128(9):1226-33. Epub 2016 Jul 25.

Max-Eder Group "Experimental Therapies for Hematologic Malignancies," Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany; Department of Internal Medicine V, and.

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http://dx.doi.org/10.1182/blood-2016-02-698092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524534PMC
September 2016

Meeting report of the 5th Heidelberg Myeloma Workshop: current status and developments in diagnosis and therapy of multiple myeloma.

J Cancer Res Clin Oncol 2016 Jan 12;142(1):247-51. Epub 2015 Jun 12.

Department of Hematology, Oncology and Rheumatology, University Hospital of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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http://link.springer.com/10.1007/s00432-015-1993-3
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http://dx.doi.org/10.1007/s00432-015-1993-3DOI Listing
January 2016

American Society of Blood and Marrow Transplantation, European Society of Blood and Marrow Transplantation, Blood and Marrow Transplant Clinical Trials Network, and International Myeloma Working Group Consensus Conference on Salvage Hematopoietic Cell Transplantation in Patients with Relapsed Multiple Myeloma.

Biol Blood Marrow Transplant 2015 Dec 30;21(12):2039-2051. Epub 2015 Sep 30.

University of Pennsylvania Abramson Cancer Center, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.bbmt.2015.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757494PMC
December 2015

Comparison of (18)F-FDG PET/CT and PET/MRI in patients with multiple myeloma.

Am J Nucl Med Mol Imaging 2015 12;5(5):469-78. Epub 2015 Oct 12.

Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center (DKFZ) Heidelberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620174PMC
November 2015

(18)F-FDG dynamic PET/CT in patients with multiple myeloma: patterns of tracer uptake and correlation with bone marrow plasma cell infiltration rate.

Clin Nucl Med 2015 Jun;40(6):e300-7

From the *Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center; †Medical Clinic V, University Hospital Heidelberg; ‡National Center for Tumor Diseases Heidelberg; §Department of Radiology, German Cancer Research Center; and ║Division of Nuclear Medicine, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/RLU.0000000000000773DOI Listing
June 2015

Extramedullary relapse after accidental head injury in a patient with multiple myeloma.

Ann Hematol 2015 Feb 29;94(2):351-3. Epub 2014 Jun 29.

Department of Hematology, University Hospital of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s00277-014-2147-4DOI Listing
February 2015

Plerixafor is effective given either preemptively or as a rescue strategy in poor stem cell mobilizing patients with multiple myeloma.

Transfusion 2015 Feb 13;55(2):275-83. Epub 2014 Aug 13.

Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany; Department of Hematology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.

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http://dx.doi.org/10.1111/trf.12813DOI Listing
February 2015

Role of magnetic resonance imaging in the management of patients with multiple myeloma: a consensus statement.

J Clin Oncol 2015 Feb 20;33(6):657-64. Epub 2015 Jan 20.

Meletios A. Dimopoulos and Evangelos Terpos, National and Kapodistrian University of Athens School of Medicine, Athens, Greece; Jens Hillengass and Hartmut Goldschmidt, University Hospital Heidelberg, Heidelberg, Germany; Saad Usmani, Carolinas Healthcare System, Charlotte, NC; Elena Zamagni and Michele Cavo, Bologna University School of Medicine, Bologna; Antonio Palumbo, S. Giovanni Battista Hospital, University of Turin, Turin, Italy; Suzanne Lentzsch, Columbia University College of Physicians and Surgeons, New York, NY; Faith E. Davies, Institute of Cancer Research, Sutton, United Kingdom; Noopur Raje, Massachusetts General Hospital Cancer Center; Kenneth Anderson, Dana-Farber Brigham and Women's Cancer Center, Harvard Medical School, Boston, MA; Orhan Sezer, Memorial Sisli Hospital, Istanbul, Turkey; Sonja Zweegman, VU University Medical Center, Amsterdam; Pieter Sonneveld, Erasmus University Medical Center, Rotterdam, the Netherlands; Jatin Shah, MD Anderson Cancer Center, Houston, TX; Ashraf Badros, University of Maryland Medical Center, Baltimore, MD; Kazuyuki Shimizu, Tokai Central Hospital, Kakamigahara, Japan; Philippe Moreau, University Hospital Hôtel-Dieu, Nantes, France; Chor-Sang Chim, Queen Mary Hospital, University of Hong Kong, Hong Kong, Special Administrative Region; Jian Hou, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China; Juan José Lahuerta, Hospital Universitario 12 de Octubre, Madrid, Spain; Artur Jurczyszyn, University Hospital, Krakow, Poland; Heinz Ludwig, Wilhelminenspital, Vienna, Austria; Bart Barlogie, University of Arkansas for Medical Sciences, Little Rock, AR; G. David Roodman, Indiana University School of Medicine, Indianapolis, IN; S. Vincent Rajkumar, Mayo Clinic, Rochester, MN; and Brian G.M. Durie, Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA.

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http://dx.doi.org/10.1200/JCO.2014.57.9961DOI Listing
February 2015

Dynamic contrast-enhanced magnetic resonance imaging for assessment of antiangiogenic treatment effects in multiple myeloma.

Clin Cancer Res 2015 Jan 28;21(1):106-12. Epub 2014 Oct 28.

Department of Hematology and Oncology, University Hospital of Heidelberg, Heidelberg, Germany. Department of Radiology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1029DOI Listing
January 2015

Whole-body low-dose computed tomography and advanced imaging techniques for multiple myeloma bone disease.

Clin Cancer Res 2014 Dec 7;20(23):5888-97. Epub 2014 Oct 7.

Department of Medicine, College of Physicians and Surgeons of Columbia University, New York-Presbyterian Hospital, New York, New York. Division of Hematology/Oncology, College of Physicians and Surgeons of Columbia University, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1692DOI Listing
December 2014

Appearance of monoclonal plasma cell diseases in whole-body magnetic resonance imaging and correlation with parameters of disease activity.

Int J Cancer 2014 Nov 17;135(10):2380-6. Epub 2014 Apr 17.

Department of Diagnostic and Interventional Radiology, University of Heidelberg, Heidelberg, Germany; Department of Radiology, German Cancer Research Center (dkfz), Heidelberg, Germany.

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http://doi.wiley.com/10.1002/ijc.28877
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http://dx.doi.org/10.1002/ijc.28877DOI Listing
November 2014

Assessing treatment response of osteolytic lesions by manual volumetry, automatic segmentation, and RECIST in experimental bone metastases.

Acad Radiol 2014 Sep 4;21(9):1177-84. Epub 2014 Jul 4.

Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany; Institute of Radiology, University Hospital Erlangen, Maximiliansplatz 1, 90154 Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2014.04.011DOI Listing
September 2014

Sensitivity of whole-body CT and MRI versus projection radiography in the detection of osteolyses in patients with monoclonal plasma cell disease.

Eur J Radiol 2014 Jul 22;83(7):1222-1230. Epub 2014 Feb 22.

Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2014.02.008DOI Listing
July 2014

Infiltration patterns in monoclonal plasma cell disorders: correlation of magnetic resonance imaging with matched bone marrow histology.

Eur J Radiol 2014 Jun 22;83(6):970-974. Epub 2014 Mar 22.

Department of Hematology and Oncology, University of Heidelberg, Heidelberg, Germany; Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X140014
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http://dx.doi.org/10.1016/j.ejrad.2014.03.005DOI Listing
June 2014

Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load.

J Clin Oncol 2013 Dec 21;31(34):4325-32. Epub 2013 Oct 21.

Kai Neben, Anna Jauch, Jens Hillengass, Nicola Lehners, Martin Granzow, Marc S. Raab, and Anthony D. Ho, University of Heidelberg; Thomas Hielscher, German Cancer Research Center; and Anja Seckinger, Hartmut Goldschmidt, and Dirk Hose,University of Heidelberg and National Center for Tumor Diseases, Heidelberg, Germany.

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http://dx.doi.org/10.1200/JCO.2012.48.4923DOI Listing
December 2013

A quantification strategy for missing bone mass in case of osteolytic bone lesions.

Med Phys 2013 Dec;40(12):123501

Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1118/1.4828843DOI Listing
December 2013

Meeting report of the 4th Heidelberg Myeloma Workshop: current status and developments in diagnosis and therapy of multiple myeloma.

J Cancer Res Clin Oncol 2013 Nov 18;139(11):1807-11. Epub 2013 Jul 18.

Department of Hematology and Oncology, University of Heidelberg, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s00432-013-1468-3DOI Listing
November 2013

Psychosocial support in patients with multiple myeloma at time of diagnosis: who wants what?

Psychooncology 2013 Oct 11;22(10):2313-20. Epub 2013 Apr 11.

Department of General Internal Medicine and Psychosomatics, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/pon.3284DOI Listing
October 2013

Challenges and opportunities of novel imaging techniques in monoclonal plasma cell disorders: imaging "early myeloma".

Leuk Lymphoma 2013 Jul 28;54(7):1355-63. Epub 2013 Jan 28.

Department of Hematology, Oncology and Rheumatology, University of Heidelberg, Heidelberg, Germany.

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https://www.tandfonline.com/doi/full/10.3109/10428194.2012.7
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http://dx.doi.org/10.3109/10428194.2012.740559DOI Listing
July 2013

Osteoporosis influences osteogenic but not angiogenic response during bone defect healing in a rat model.

Injury 2013 Jul 20;44(7):923-9. Epub 2013 Mar 20.

Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.injury.2013.02.029DOI Listing
July 2013

Meeting report of the third Heidelberg myeloma workshop: current status and developments in diagnosis and therapy of multiple myeloma.

J Cancer Res Clin Oncol 2012 Jan 30;138(1):173-8. Epub 2011 Sep 30.

Department of Hematology and Oncology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00432-011-1071-4DOI Listing
January 2012

Radiotherapy of solitary plasmacytoma.

Ann Hematol 2011 Sep 19;90(9):1093-7. Epub 2011 Feb 19.

Department of Radiation Oncology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00277-011-1190-7DOI Listing
September 2011

Monoclonal gammopathy and smoldering multiple myeloma: diagnosis, staging, prognosis, management.

Recent Results Cancer Res 2011 ;183:113-31

Department of Medicine V, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-3-540-85772-3_6DOI Listing
June 2011

Staging monoclonal plasma cell disease: comparison of the Durie-Salmon and the Durie-Salmon PLUS staging systems.

Radiology 2010 Oct;257(1):195-204

Department of Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany.

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http://dx.doi.org/10.1148/radiol.10091809DOI Listing
October 2010