Jenny E Gunton

Jenny E Gunton

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Jenny E Gunton

Publications by authors named "Jenny E Gunton"

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Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis.

PLoS One 2019 4;14(12):e0225332. Epub 2019 Dec 4.

Centre for Diabetes, Obesity and Endocrinology, The Westmead Institute for Medical Research, The University of Sydney, Sydney, NSW, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0225332PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892561PMC
March 2020

Mice with myocyte deletion of vitamin D receptor have sarcopenia and impaired muscle function.

J Cachexia Sarcopenia Muscle 2019 Dec 21;10(6):1228-1240. Epub 2019 Jun 21.

Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1002/jcsm.12460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903451PMC
December 2019

The Changing Landscape of Pharmacotherapy for Diabetes Mellitus: A Review of Cardiovascular Outcomes.

Int J Mol Sci 2019 Nov 21;20(23). Epub 2019 Nov 21.

Centre for Diabetes, Obesity and Endocrinology, The Westmead Institute for Medical Research, The University of Sydney, NSW 2145, Australia.

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http://dx.doi.org/10.3390/ijms20235853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928800PMC
November 2019

Iodine deficiency in women of childbearing age: not bread alone?

Asia Pac J Clin Nutr 2018;27(4):853-859

Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, Australia.

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http://dx.doi.org/10.6133/apjcn.102017.02DOI Listing
September 2019

β Cell Hypoxia-Inducible Factor-1α Is Required for the Prevention of Type 1 Diabetes.

Cell Rep 2019 05;27(8):2370-2384.e6

Center for Diabetes, Obesity, and Endocrinology (CDOE), The Westmead Institute for Medical Research (WIMR), The University of Sydney, Sydney, NSW, Australia; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia; St Vincent's Clinical School, University of New South Wales, Kensington, NSW, Australia; Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, NSW, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193056
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http://dx.doi.org/10.1016/j.celrep.2019.04.086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661122PMC
May 2019

Vitamin D Improves Cardiac Function After Myocardial Infarction Through Modulation of Resident Cardiac Progenitor Cells.

Heart Lung Circ 2018 Aug 3;27(8):967-975. Epub 2018 Feb 3.

Centre for Heart Research, Westmead Institute for Medical Research, The University of Sydney, Sydney, NSW, Australia; Department of Cardiology, Westmead Hospital, Sydney, NSW, Australia; Sydney Medical School, The University of Sydney, Sydney, NSW, Australia; Victor Chang Cardiac Research Institute, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.hlc.2018.01.006DOI Listing
August 2018

Women with type 2 diabetes in pregnancy remain a high-risk group.

Minerva Endocrinol 2018 Jun;43(2):224-225

Department of Diabetes, Endocrinology and Metabolism, the Northern Clinical School, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, Australia.

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http://dx.doi.org/10.23736/S0391-1977.17.02653-0DOI Listing
June 2018

Vitamin D and muscle.

Bone Rep 2018 Jun 18;8:163-167. Epub 2018 Apr 18.

Centre for Diabetes, Obesity and Endocrinology Research, The Westmead Institute of Medical Research, Westmead, Sydney, Australia.

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http://dx.doi.org/10.1016/j.bonr.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021354PMC
June 2018

Vitamin D and the Liver-Correlation or Cause?

Nutrients 2018 Apr 16;10(4). Epub 2018 Apr 16.

Centre for Diabetes, Obesity & Endocrinology, The Westmead Institute for Medical Research (WIMR), Westmead, Sydney, NSW 2145, Australia.

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http://dx.doi.org/10.3390/nu10040496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946281PMC
April 2018

The Geometric Framework for Nutrition as a tool in precision medicine.

Nutr Healthy Aging 2017 Dec 7;4(3):217-226. Epub 2017 Dec 7.

Charles Perkins Centre, The University of Sydney, NSW, Australia.

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http://dx.doi.org/10.3233/NHA-170027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734128PMC
December 2017

Diabetes Medications and Cardiovascular Outcomes in Type 2 Diabetes.

Heart Lung Circ 2017 Nov 10;26(11):1133-1141. Epub 2017 Apr 10.

Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, NSW, Australia; The Westmead Institute for Medical Research, The University of Sydney, Sydney, NSW, Australia; Sydney Medical School, The University of Sydney, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.hlc.2017.02.030DOI Listing
November 2017

Transplantation sites for porcine islets.

Diabetologia 2017 10 21;60(10):1972-1976. Epub 2017 Jul 21.

National Pancreas and Islet Transplant Unit, University of Sydney, Westmead Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1007/s00125-017-4363-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448811PMC
October 2017

Transplantation sites for human and murine islets.

Diabetologia 2017 10 22;60(10):1961-1971. Epub 2017 Jul 22.

Centre for Diabetes, Obesity & Endocrinology, The Westmead Institute for Medical Research (WIMR), Room 2040, Level 2, Darcy Rd, Westmead Hospital, The University of Sydney, Sydney, NSW, 2145, Australia.

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http://dx.doi.org/10.1007/s00125-017-4362-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448863PMC
October 2017

Islet Transplantation Provides Superior Glycemic Control With Less Hypoglycemia Compared With Continuous Subcutaneous Insulin Infusion or Multiple Daily Insulin Injections.

Transplantation 2017 06;101(6):1268-1275

1 Department of Endocrinology, University of Sydney at Westmead Hospital, NSW, Australia. 2 Centre for Diabetes, Obesity and Endocrinology Research, The Westmead Institute, University of Sydney at Westmead Hospital, Sydney, Australia. 3 Department of Diabetes and Endocrinology, Westmead Hospital Westmead, NSW, Australia. 4 National Pancreas Transplant Unit, University of Sydney at Westmead Hospital, Westmead Hospital, Westmead, NSW, Australia. 5 Centre for Renal and Transplant Research, Westmead Millennium Institute, University of Sydney at Westmead, NSW, Australia. 6 Department of Renal Medicine, Westmead Hospital, NSW, Australia. 7 Department of Paediatrics, Murdoch Children's Research Institute and University of Melbourne, Victoria, Australia. 8 St Vincent's Institute, University of Melbourne, Victoria, Australia. 9 Departments of Endocrinology and Clinical Biochemistry, St Vincent's Hospital, Melbourne, Victoria, Australia. 10 Department of Pathology, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1097/TP.0000000000001381DOI Listing
June 2017

Vitamin D in liver disease: Current evidence and potential directions.

Biochim Biophys Acta Mol Basis Dis 2017 04 4;1863(4):907-916. Epub 2017 Jan 4.

The Garvan Institute of Medical Research, The University of New South Wales (UNSW), Sydney, NSW, Australia; The Westmead Institute of Medical Research, The University of Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.01.001DOI Listing
April 2017

Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.

Diabetologia 2016 07 4;59(7):1492-1502. Epub 2016 Apr 4.

Garvan Institute of Medical Research, St Vincent's Hospital, UNSW Australia, 384 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia.

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http://dx.doi.org/10.1007/s00125-016-3947-yDOI Listing
July 2016

Changes in beta cell function occur in prediabetes and early disease in the Lepr (db) mouse model of diabetes.

Diabetologia 2016 06 5;59(6):1222-30. Epub 2016 Apr 5.

School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1007/s00125-016-3942-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869737PMC
June 2016

Bone Mineral Density in Postmenopausal Women Heterozygous for the C282Y HFE Mutation.

J Osteoporos 2016 31;2016:5638273. Epub 2016 Mar 31.

Department of Endocrinology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia; Northern Clinical School, University of Sydney, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.

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http://dx.doi.org/10.1155/2016/5638273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830734PMC
April 2016

Hepatocyte-specific deletion of ARNT (aryl hydrocarbon Receptor Nuclear Translocator) results in altered fibrotic gene expression in the thioacetamide model of liver injury.

PLoS One 2015 26;10(3):e0121650. Epub 2015 Mar 26.

Diabetes, Obesity & Endocrinology Group, Westmead Millennium Institute, Westmead Hospital, Sydney, NSW, Australia; Faculty of Medicine, University of Sydney, Westmead, Sydney, NSW, Australia; Diabetes and Transcription Factors Group, Garvan Institute of Medical Research, Sydney, NSW, Australia; St. Vincent's Clinical School, University of NSW, Sydney, NSW, Australia; Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, NSW Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121650PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374875PMC
March 2016

Fluconazole in the treatment of Cushing's disease.

Endocrinol Diabetes Metab Case Rep 2016 20;2016:150115. Epub 2016 Jan 20.

Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, 2145, Australia; Faculty of Medicine, Westmead Hospital, University of Sydney, Sydney, 2145, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, 2010, Australia; Diabetes and Transcription Factors Group, Garvan Institute of Medical Research (GIMR), Sydney, 2010, Australia; Department of Diabetes, Obesity and Endocrinology, The Westmead Institute for Medical Research, The University of Sydney, Sydney, 2045, Australia.

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http://dx.doi.org/10.1530/EDM-15-0115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744941PMC
February 2016

Vitamin D Receptor Ablation and Vitamin D Deficiency Result in Reduced Grip Strength, Altered Muscle Fibers, and Increased Myostatin in Mice.

Calcif Tissue Int 2015 Dec 4;97(6):602-10. Epub 2015 Sep 4.

Westmead Millennium Institute, 176 Hawkesbury Rd, Westmead, Sydney, NSW, 2145, Australia.

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http://dx.doi.org/10.1007/s00223-015-0054-xDOI Listing
December 2015

Triple therapy in type 2 diabetes; a systematic review and network meta-analysis.

PeerJ 2015 7;3:e1461. Epub 2015 Dec 7.

Centre for Applied Health Economics, Menzies Health Institute Queensland, Griffith University , Queensland , Australia.

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http://dx.doi.org/10.7717/peerj.1461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675096PMC
December 2015

Bone muscle interactions and vitamin D.

Bone 2015 Nov 6;80:89-94. Epub 2015 Mar 6.

Department of Internal Medicine/Endocrinology, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bone.2015.02.029DOI Listing
November 2015

Assessment of cardiovascular risk in diabetes: Risk scores and provocative testing.

World J Diabetes 2015 May;6(4):634-41

Teresa Lam, Kharis Burns, N Wah Cheung, Jenny E Gunton, Department of Diabetes and Endocrinology, Westmead Hospital, Sydney 2145, Australia.

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http://dx.doi.org/10.4239/wjd.v6.i4.634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434084PMC
May 2015

Higher ferritin levels, but not serum iron or transferrin saturation, are associated with Type 2 diabetes mellitus in adult men and women free of genetic haemochromatosis.

Clin Endocrinol (Oxf) 2015 Apr 23;82(4):525-32. Epub 2014 Jul 23.

School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia; Department of Endocrinology and Diabetes, Fremantle Hospital, Fremantle, WA, Australia.

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http://dx.doi.org/10.1111/cen.12529DOI Listing
April 2015

Deletion of ARNT (Aryl hydrocarbon receptor nuclear translocator) in β-cells causes islet transplant failure with impaired β-cell function.

PLoS One 2014 30;9(5):e98435. Epub 2014 May 30.

Diabetes and Transcription Factors Group, Garvan Institute of Medical Research (GIMR), Sydney, Australia; Faculty of Medicine, Westmead Hospital, University of Sydney, Sydney, Australia; St Vincent's Clinical School, University of New South Wales, Sydney, Australia; Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098435PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039512PMC
January 2015

A new blood glucose management algorithm for type 2 diabetes: a position statement of the Australian Diabetes Society.

Med J Aust 2014 Dec;201(11):650-3

Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.5694/mja14.01187DOI Listing
December 2014

The vitamin D receptor (VDR) is expressed in skeletal muscle of male mice and modulates 25-hydroxyvitamin D (25OHD) uptake in myofibers.

Endocrinology 2014 Sep 20;155(9):3227-37. Epub 2014 Jun 20.

Garvan Institute of Medical Research (C.M.G., N.M., K.M.C., J.E.G.), Sydney, New South Wales, Australia 2010; Faculties of Medicine (C.M.G., M.A., R.S.M., R.J.C.-B., J.E.G.) and Veterinary Science (D.R.F.) University of Sydney, Sydney, New South Wales, Australia 2145; Bosch Institute (M.A., R.S.M.), University of Sydney, Sydney, New South Wales, Australia 2006; Murdoch Childrens Research Institute (P.J.H.), Melbourne, Victoria, Australia 3000; The Kolling Institute of Medical Research (R.J.C.-B.), Sydney, New South Wales, Australia 2065; Royal North Shore Hospital (R.J.C.-B.), Sydney, New South Wales, Australia 2065; Department of Endocrinology and Diabetes (J.E.G.), Westmead Hospital, Sydney, New South Wales, Australia 2145; and St Vincent's Clinical School (J.E.G.), University of New South Wales, Sydney, New South Wales, Australia 2010.

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http://dx.doi.org/10.1210/en.2014-1016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207908PMC
September 2014

Beta-cell ARNT is required for normal glucose tolerance in murine pregnancy.

PLoS One 2013 24;8(10):e77419. Epub 2013 Oct 24.

Diabetes and Transcription Factors Group, Garvan Institute of Medical Research, Sydney, Australia ; Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077419PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812008PMC
August 2014

Reduction of ARNT in myeloid cells causes immune suppression and delayed wound healing.

Am J Physiol Cell Physiol 2014 Aug 2;307(4):C349-57. Epub 2014 Jul 2.

Diabetes and Transcription Factors Group, Department of Immunology and Inflammation, Garvan Institute of Medical Research, Sydney, New South Wales, Australia; Faculty of Medicine, University of Sydney, Sydney, New South Wales, Australia; St. Vincent's Clinical School, University of New South Wales, Sydney, New South Wales, Australia; and Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, New South Wales, Australia

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http://www.physiology.org/doi/10.1152/ajpcell.00306.2013
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http://dx.doi.org/10.1152/ajpcell.00306.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137137PMC
August 2014

Vitamin D supplementation and the effects on glucose metabolism during pregnancy: a randomized controlled trial.

Diabetes Care 2014 Jul 23;37(7):1837-44. Epub 2014 Apr 23.

Diabetes and Endocrinology, Westmead Hospital, Sydney, New South Wales, AustraliaSchool of Medicine, University of Western Sydney, Sydney, New South Wales, Australia.

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http://care.diabetesjournals.org/content/early/2014/04/18/dc
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http://care.diabetesjournals.org/lookup/doi/10.2337/dc14-015
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http://dx.doi.org/10.2337/dc14-0155DOI Listing
July 2014

A computational proof of concept of a machine-intelligent artificial pancreas using Lyapunov stability and differential game theory.

J Diabetes Sci Technol 2014 Jul 4;8(4):791-806. Epub 2014 Jul 4.

Westmead Clinical School, University of Sydney, Sydney, Australia Diabetes and Transcription Factors Group, Garvan Institute of Medical Research, Darlinghurst, Australia St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Kensington, Australia Diabetes and Endocrinology, Westmead Hospital, Sydney, Australia.

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http://dx.doi.org/10.1177/1932296814536271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764243PMC
July 2014

Effects of vitamin D in skeletal muscle: falls, strength, athletic performance and insulin sensitivity.

Clin Endocrinol (Oxf) 2014 Feb;80(2):169-81

Diabetes and Transcription Factors Group, Garvan Institute of Medical Research (GIMR), Sydney, NSW, Australia; Faculty of Medicine, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/cen.12368DOI Listing
February 2014

Vitamin D signaling regulates proliferation, differentiation, and myotube size in C2C12 skeletal muscle cells.

Endocrinology 2014 Feb 26;155(2):347-57. Epub 2013 Nov 26.

Garvan Institute of Medical Research (C.M.G., N.M., K.C., J.E.G.), Sydney, New South Wales 2010, Australia; Faculty of Medicine (C.M.G., R.J.C.-B., J.E.G.), University of Sydney, Sydney, New South Wales 2008, Australia; The Kolling Institute of Medical Research (R.J.C.-B.) and Royal North Shore Hospital (R.J.C.-B.), Sydney, New South Wales 2065, Australia; Department of Endocrinology and Diabetes (J.E.G.), Westmead Hospital, Sydney, New South Wales 2145, Australia; and St Vincent's Clinical School (J.E.G.), University of New South Wales, Sydney, New South Wales 2052, Australia.

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http://dx.doi.org/10.1210/en.2013-1205DOI Listing
February 2014

The roles of vitamin D in skeletal muscle: form, function, and metabolism.

Endocr Rev 2013 Feb 20;34(1):33-83. Epub 2012 Nov 20.

Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1210/er.2012-1012DOI Listing
February 2013

The influence of ethnicity on the development of type 2 diabetes mellitus in women with gestational diabetes: a prospective study and review of the literature.

ISRN Endocrinol 2012 17;2012:341638. Epub 2012 Apr 17.

Diabetes and Transcription Factors Group, Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.

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https://www.hindawi.com/archive/2012/341638/
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http://dx.doi.org/10.5402/2012/341638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345225PMC
August 2012

Novel links between HIFs, type 2 diabetes, and metabolic syndrome.

Trends Endocrinol Metab 2012 Aug 4;23(8):372-80. Epub 2012 Jul 4.

Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S10432760120007
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http://dx.doi.org/10.1016/j.tem.2012.05.003DOI Listing
August 2012

Islet transplantation: factors in short-term islet survival.

Arch Immunol Ther Exp (Warsz) 2011 Dec 8;59(6):421-9. Epub 2011 Oct 8.

Diabetes and Transcription Factors, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.

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http://dx.doi.org/10.1007/s00005-011-0143-0DOI Listing
December 2011

Serum 25-hydroxyvitamin D and glycated haemoglobin levels in women with gestational diabetes mellitus.

Med J Aust 2011 Apr;194(7):334-7

Westmead Hospital, Sydney, NSW, Australia.

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April 2011

Clinical islet transplantation in type 1 diabetes mellitus: results of Australia's first trial.

Med J Aust 2006 Mar;184(5):221-5

National Pancreas Transplant Unit, University of Sydney at Westmead Hospital, Darcy Road, Westmead, NSW 2145, Australia.

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March 2006

Metformin use as an adjunct to insulin treatment.

Med J Aust 2003 Jun;178(11):591-2

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June 2003

Metformin rapidly increases insulin receptor activation in human liver and signals preferentially through insulin-receptor substrate-2.

J Clin Endocrinol Metab 2003 Mar;88(3):1323-32

Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St. Leonards, Sydney, New South Wales 2065 Australia.

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http://dx.doi.org/10.1210/jc.2002-021394DOI Listing
March 2003

Outcome of pregnancy complicated by pre-gestational diabetes--improvement in outcomes.

Aust N Z J Obstet Gynaecol 2002 Nov;42(5):478-81

Department of Endocrinology, Royal North Shore Hospital, St Leonards, Sydney, Australia.

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http://dx.doi.org/10.1111/j.0004-8666.2002.00478.xDOI Listing
November 2002

Neonatal thyroid-stimulating hormone concentrations in northern Sydney: further indications of mild iodine deficiency?

Med J Aust 2002 Apr;176(7):317-20

Department of Endocrinology, Royal North Shore Hospital, St Leonards, NSW.

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April 2002