Jenny E Gumperz

Jenny E Gumperz

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Jenny E Gumperz

Jenny E Gumperz

Publications by authors named "Jenny E Gumperz"

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Mucosal-Associated Invariant T Cells in Tumors of Epithelial Origin.

Adv Exp Med Biol 2020 ;1224:63-77

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

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http://dx.doi.org/10.1007/978-3-030-35723-8_5DOI Listing
February 2020

Expansion and Adoptive Transfer of Human Vδ2 T Cells to Assess Antitumor Effects In Vivo.

Methods Mol Biol 2019 ;1884:57-72

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

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http://dx.doi.org/10.1007/978-1-4939-8885-3_4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483093PMC
June 2019

Modeling Human Antitumor Responses Using Umbilical Cord Blood-Engrafted Mice.

Front Immunol 2018 26;9:54. Epub 2018 Jan 26.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790779PMC
February 2019

LFA-1 Ligation by High-Density ICAM-1 Is Sufficient To Activate IFN-γ Release by Innate T Lymphocytes.

J Immunol 2018 10 31;201(8):2452-2461. Epub 2018 Aug 31.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706; and

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http://dx.doi.org/10.4049/jimmunol.1800537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179935PMC
October 2018

Mucosal associated invariant T cells from human breast ducts mediate a Th17-skewed response to bacterially exposed breast carcinoma cells.

Breast Cancer Res 2018 09 12;20(1):111. Epub 2018 Sep 12.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

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http://dx.doi.org/10.1186/s13058-018-1036-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134631PMC
September 2018

Human Invariant NKT Cells Induce IL-1β Secretion by Peripheral Blood Monocytes via a P2X7-Independent Pathway.

J Immunol 2016 09 17;197(6):2455-64. Epub 2016 Aug 17.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706; and

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http://dx.doi.org/10.4049/jimmunol.1600790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011004PMC
September 2016

Human iNKT Cells Promote Protective Inflammation by Inducing Oscillating Purinergic Signaling in Monocyte-Derived DCs.

Cell Rep 2016 09;16(12):3273-3285

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043518PMC
http://dx.doi.org/10.1016/j.celrep.2016.08.061DOI Listing
September 2016

Are human iNKT cells keeping tabs on lipidome perturbations triggered by oxidative stress in the blood?

Immunogenetics 2016 08 8;68(8):611-22. Epub 2016 Jul 8.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA.

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http://dx.doi.org/10.1007/s00251-016-0936-8DOI Listing
August 2016

PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse Model.

PLoS Pathog 2016 05 17;12(5):e1005642. Epub 2016 May 17.

Departments of Oncology and Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871349PMC
May 2016

Analysis of Immune Cells from Human Mammary Ductal Epithelial Organoids Reveals Vδ2+ T Cells That Efficiently Target Breast Carcinoma Cells in the Presence of Bisphosphonate.

Cancer Prev Res (Phila) 2016 Apr 25;9(4):305-16. Epub 2016 Jan 25.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

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http://dx.doi.org/10.1158/1940-6207.CAPR-15-0370-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818696PMC
April 2016

Transcriptional regulation of the human TNFSF11 gene in T cells via a cell type-selective set of distal enhancers.

J Cell Biochem 2015 Feb;116(2):320-30

Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706.

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http://dx.doi.org/10.1002/jcb.24974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303342PMC
February 2015

Expression of CD1c enhances human invariant NKT cell activation by α-GalCer.

Cancer Immun 2013 10;13. Epub 2013 May 10.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721260PMC
May 2014

Mice engrafted with human fetal thymic tissue and hematopoietic stem cells develop pathology resembling chronic graft-versus-host disease.

Biol Blood Marrow Transplant 2013 Sep 24;19(9):1310-22. Epub 2013 Jun 24.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1016/j.bbmt.2013.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755109PMC
September 2013

Human invariant natural killer T cells acquire transient innate responsiveness via histone H4 acetylation induced by weak TCR stimulation.

J Exp Med 2012 May 16;209(5):987-1000. Epub 2012 Apr 16.

Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1084/jem.20111024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348100PMC
May 2012

Analysis of the CD1 antigen presenting system in humanized SCID mice.

PLoS One 2011 30;6(6):e21701. Epub 2011 Jun 30.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021701PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128084PMC
December 2011

A live imaging cell motility screen identifies prostaglandin E2 as a T cell stop signal antagonist.

J Immunol 2011 Oct 7;187(7):3663-70. Epub 2011 Sep 7.

Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.4049/jimmunol.1100103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178752PMC
October 2011

Human NKT cells direct the differentiation of myeloid APCs that regulate T cell responses via expression of programmed cell death ligands.

J Autoimmun 2011 Aug 12;37(1):28-38. Epub 2011 Apr 12.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, 53706, USA.

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http://dx.doi.org/10.1016/j.jaut.2011.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110565PMC
August 2011

Natural killer T cells: innate lymphocytes positioned as a bridge between acute and chronic inflammation?

Microbes Infect 2010 Dec 17;12(14-15):1125-33. Epub 2010 Sep 17.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

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http://dx.doi.org/10.1016/j.micinf.2010.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998565PMC
December 2010

Autoreactive natural killer T cells: promoting immune protection and immune tolerance through varied interactions with myeloid antigen-presenting cells.

Immunology 2010 Aug 11;130(4):471-83. Epub 2010 May 11.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.

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http://dx.doi.org/10.1111/j.1365-2567.2010.03293.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913258PMC
August 2010

Human NKT cells promote monocyte differentiation into suppressive myeloid antigen-presenting cells.

J Leukoc Biol 2009 Oct;86(4):757-68

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1189/jlb.0209059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752012PMC
October 2009

Recognition of lyso-phospholipids by human natural killer T lymphocytes.

PLoS Biol 2009 Oct 27;7(10):e1000228. Epub 2009 Oct 27.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1371/journal.pbio.1000228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760207PMC
October 2009

Serum lipids regulate dendritic cell CD1 expression and function.

Immunology 2008 Nov 28;125(3):289-301. Epub 2008 Apr 28.

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/j.1365-2567.2008.02842.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669133PMC
November 2008

Natural killer T-cell autoreactivity leads to a specialized activation state.

Blood 2008 Nov 8;112(10):4128-38. Epub 2008 Sep 8.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, USA.

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http://dx.doi.org/10.1182/blood-2008-05-157529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581981PMC
November 2008

Modulation of CD1d-restricted NKT cell responses by CD4.

J Leukoc Biol 2007 Dec 28;82(6):1455-65. Epub 2007 Aug 28.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, USA.

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http://dx.doi.org/10.1189/jlb.0307163DOI Listing
December 2007

NKT cells direct monocytes into a DC differentiation pathway.

J Leukoc Biol 2007 May 20;81(5):1224-35. Epub 2007 Feb 20.

Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, 1300 University Ave., Madison, WI 53705, USA.

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http://dx.doi.org/10.1189/jlb.1206718DOI Listing
May 2007

Distinct endosomal trafficking requirements for presentation of autoantigens and exogenous lipids by human CD1d molecules.

J Immunol 2007 May;178(10):6181-90

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.

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http://dx.doi.org/10.4049/jimmunol.178.10.6181DOI Listing
May 2007

Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors.

J Immunol 2006 Mar;176(6):3625-34

Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, 1300 University Avenue, Madison, WI 53706, USA.

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http://dx.doi.org/10.4049/jimmunol.176.6.3625DOI Listing
March 2006

The ins and outs of CD1 molecules: bringing lipids under immunological surveillance.

Authors:
Jenny E Gumperz

Traffic 2006 Jan;7(1):2-13

Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, 53706, USA,

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http://dx.doi.org/10.1111/j.1600-0854.2005.00364.xDOI Listing
January 2006

Regulation of CD1d expression and function by a herpesvirus infection.

J Clin Invest 2005 May;115(5):1369-78

George Williams Hooper Foundation, University of California, San Francisco, 94143, USA.

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http://dx.doi.org/10.1172/JCI24041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087176PMC
May 2005

CD1d-restricted "NKT" cells and myeloid IL-12 production: an immunological crossroads leading to promotion or suppression of effective anti-tumor immune responses?

Authors:
Jenny E Gumperz

J Leukoc Biol 2004 Aug 3;76(2):307-13. Epub 2004 May 3.

Department of Microbiology and Immunology, University of Wisconsin Medical School, Service Memorial Institutes, Room 405, 1300 University Ave., Madison, WI 53706, USA.

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http://dx.doi.org/10.1189/jlb.0104038DOI Listing
August 2004

Antigen specificity of semi-invariant CD1d-restricted T cell receptors: the best of both worlds?

Authors:
Jenny E Gumperz

Immunol Cell Biol 2004 Jun;82(3):285-94

Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, 1300 University Avenue, Madison, WI 53706, USA.

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http://dx.doi.org/10.1111/j.0818-9641.2004.01257.xDOI Listing
June 2004

Mechanism of CD1d-restricted natural killer T cell activation during microbial infection.

Nat Immunol 2003 Dec 26;4(12):1230-7. Epub 2003 Oct 26.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://www.nature.com/articles/ni1002
Publisher Site
http://dx.doi.org/10.1038/ni1002DOI Listing
December 2003

Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development.

J Immunol 2003 Oct;171(8):4149-55

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.4049/jimmunol.171.8.4149DOI Listing
October 2003

CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells.

J Immunol 2003 Sep;171(5):2571-80

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.4049/jimmunol.171.5.2571DOI Listing
September 2003

Understanding the function of CD1-restricted T cells.

Nat Immunol 2003 Jun;4(6):517-23

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, One Jimmy Fund Way, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ni0603-517DOI Listing
June 2003

Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission.

Int Immunol 2003 Feb;15(2):279-88

Department of Immunology, National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8502, Japan.

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http://dx.doi.org/10.1093/intimm/dxg029DOI Listing
February 2003

CD1-dependent dendritic cell instruction.

Nat Immunol 2002 Dec 4;3(12):1163-8. Epub 2002 Nov 4.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, One Jimmy Fund Way, Boston, MA 02115, USA.

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http://dx.doi.org/10.1038/ni851DOI Listing
December 2002

Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining.

J Exp Med 2002 Mar;195(5):625-36

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, One Jimmy Fund Way, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193772PMC
http://dx.doi.org/10.1084/jem.20011786DOI Listing
March 2002