Publications by authors named "Jenny C Chang"

91Publications

A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations.

Breast Cancer Res 2020 11 4;22(1):121. Epub 2020 Nov 4.

Houston Methodist Research Institute, 6670 Bertner Ave, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s13058-020-01353-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640663PMC
November 2020

Metastatic triple-negative breast cancer: Established and emerging treatments.

Breast J 2020 Jun 23. Epub 2020 Jun 23.

Houston Methodist Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1111/tbj.13946DOI Listing
June 2020

Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression.

Nat Commun 2019 08 14;10(1):3668. Epub 2019 Aug 14.

Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, 44106, USA.

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http://dx.doi.org/10.1038/s41467-019-11640-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694140PMC
August 2019

The impact of molecular status on survival outcomes for invasive micropapillary carcinoma of the breast.

Breast J 2019 11 18;25(6):1171-1176. Epub 2019 Jul 18.

Department of Radiation Oncology, Houston Methodist Hospital, Houston, Texas.

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http://dx.doi.org/10.1111/tbj.13432DOI Listing
November 2019

NO and COX2: Dual targeting for aggressive cancers.

Proc Natl Acad Sci U S A 2017 12 13;114(52):13591-13593. Epub 2017 Dec 13.

Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261

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http://dx.doi.org/10.1073/pnas.1717440114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748226PMC
December 2017

The lncRNA BORG Drives Breast Cancer Metastasis and Disease Recurrence.

Sci Rep 2017 10 5;7(1):12698. Epub 2017 Oct 5.

Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, 44106, USA.

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http://dx.doi.org/10.1038/s41598-017-12716-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629202PMC
October 2017

Treatment Outcomes and Prognostic Factors in Male Patients With Stage IV Breast Cancer: A Population-based Study.

Clin Breast Cancer 2018 02 10;18(1):e97-e105. Epub 2017 Aug 10.

Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2017.07.005DOI Listing
February 2018

Mutant p53 dictates the oncogenic activity of c-Abl in triple-negative breast cancers.

Cell Death Dis 2017 06 29;8(6):e2899. Epub 2017 Jun 29.

Case Comprehensive Cancer Center, Division of General Medical Sciences-Oncology, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1038/cddis.2017.294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520943PMC
June 2017

Role of RPL39 in Metaplastic Breast Cancer.

J Natl Cancer Inst 2017 06 31;109(6). Epub 2016 Dec 31.

Affiliations of authors: Houston Methodist Cancer Center, Houston, TX (BD, DDG, ZBL, HW, SG, DHS, JEE, JCC); Division of Basic Science Research, Department of Systems Biology (NEE, AKE, GBM), and Division of Pathology/Lab Medicine, Department of Pathology (MZG), The University of Texas MD Anderson Cancer Center, Houston, TX; Department of Breast Surgery, Shanghai Cancer Center and Cancer Institute of Fudan University, Shanghai, China (ZBL); Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA (XL); Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY (OE); Joan and Sanford I. Weill Medical School of Cornell University, New York, NY (SSG); Department of Medicine, Indiana University Medical School, Indianapolis, IN (KDM); Departments of Surgery and Medical and Molecular Genetics, IU Center for Computational Biology and Bioinformatics, Indianapolis, IN (MR).

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djw292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245334PMC
June 2017

Cancer stem cells: A nuanced perspective.

Medicine (Baltimore) 2016 Sep;95(1 Suppl 1):S26-8

aDepartment of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH bThe Sidney Kimmel Comprehensive Center, The Johns Hopkins University School of Medicine, Baltimore, MD cCancer Center, Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX.

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http://dx.doi.org/10.1097/MD.0000000000004559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599213PMC
September 2016

Cancer stem cells: Role in tumor growth, recurrence, metastasis, and treatment resistance.

Authors:
Jenny C Chang

Medicine (Baltimore) 2016 Sep;95(1 Suppl 1):S20-5

aCancer Center bInstitute for Academic Medicine, Houston Methodist Hospital, Houston, TX.

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http://dx.doi.org/10.1097/MD.0000000000004766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599212PMC
September 2016

Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence.

Sci Transl Med 2016 Apr;8(334):334ra53

Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA. Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA. Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad3001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256931PMC
April 2016

The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair.

Cancer Lett 2016 07 6;376(2):249-58. Epub 2016 Apr 6.

Houston Methodist Research Institute, 6670 Bertner Ave., Houston, TX 77030, United States; Houston Methodist Cancer Center, Houston Methodist Hospital, 6445 Main St., OPC 24, Houston, TX 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864217PMC
July 2016

Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival.

Cancer Res 2016 04 26;76(7):1942-53. Epub 2016 Feb 26.

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873402PMC
April 2016

Antitumor activity of Cetuximab in combination with Ixabepilone on triple negative breast cancer stem cells.

Breast Cancer Res 2016 Jan 12;18(1). Epub 2016 Jan 12.

Methodist Cancer Center, Houston Methodist Hospital, 6445 Main Street, P21-34, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s13058-015-0662-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711100PMC
January 2016

Dual HER2 blockade: preclinical and clinical data.

Breast Cancer Res 2014 Aug 1;16(4):419. Epub 2014 Aug 1.

Division of Hemotology and Oncology, College of Medicine, Mayo Clinic, 4500 San Pablo Rd S., Jacksonville, FL, 32224, USA.

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http://dx.doi.org/10.1186/s13058-014-0419-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429364PMC
August 2014

Erratum: Dual HER2 blockade: preclinical and clinical data.

Breast Cancer Res 2014 Nov 6;16(6):468. Epub 2014 Nov 6.

Division of Hemotology and Oncology, College of Medicine, Mayo Clinic, 4500 San Pablo Road South, Jacksonville, FL, 32224, USA.

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http://dx.doi.org/10.1186/s13058-014-0468-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303199PMC
November 2014

Eniluracil plus 5-fluorouracil and leucovorin: treatment for metastatic breast cancer patients in whom capecitabine treatment rapidly failed.

Clin Breast Cancer 2014 Feb 1;14(1):26-30. Epub 2013 Nov 1.

Spector Consulting Services, Durham, NC. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2013.08.018DOI Listing
February 2014

Modeling of nanotherapeutics delivery based on tumor perfusion.

New J Phys 2013 May;15:55004

Department of Nanomedicine, The Methodist Hospital Research Institute, 6670 Bertner Avenue, Houston, TX 77030.

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http://dx.doi.org/10.1088/1367-2630/15/5/055004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770306PMC
May 2013

Development of acneiform rash does not predict response to lapatinib treatment in patients with breast cancer.

Pharmacotherapy 2013 Oct 6;33(10):1126-9. Epub 2013 Jun 6.

University of Houston College of Pharmacy, Houston, Texas.

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http://dx.doi.org/10.1002/phar.1308DOI Listing
October 2013

Prognostic markers for invasive micropapillary carcinoma of the breast: a population-based analysis.

Clin Breast Cancer 2013 Apr;13(2):133-9

Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.clbc.2012.10.001DOI Listing
April 2013

Trastuzumab-resistant cells rely on a HER2-PI3K-FoxO-survivin axis and are sensitive to PI3K inhibitors.

Cancer Res 2013 Feb 29;73(3):1190-200. Epub 2012 Nov 29.

Departments of Cancer Biology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-2440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563941PMC
February 2013

Microenvironmental regulation of epithelial-mesenchymal transitions in cancer.

Cancer Res 2012 Oct 20;72(19):4883-9. Epub 2012 Sep 20.

Department of Cardiothoracic Surgery, Neuberger Berman Lung Cancer Research Center, Weill Cornell Medical College of Cornell University, New York, New York10065, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649848PMC
October 2012

Epithelial-mesenchymal transition, cancer stem cells and treatment resistance.

Breast Cancer Res 2012 Jan 19;14(1):202. Epub 2012 Jan 19.

Methodist Hospital Cancer Center, 6550 Fannin Street SM383, Houston, TX 77030, USA.

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http://dx.doi.org/10.1186/bcr2938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496111PMC
January 2012

A gene transcription signature of obesity in breast cancer.

Breast Cancer Res Treat 2012 Apr 13;132(3):993-1000. Epub 2011 Jul 13.

Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.

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http://link.springer.com/10.1007/s10549-011-1595-y
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http://dx.doi.org/10.1007/s10549-011-1595-yDOI Listing
April 2012

Stat5: from breast development to cancer prognosis, prediction, and progression.

J Clin Oncol 2011 Jun 16;29(18):2443-4. Epub 2011 May 16.

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http://dx.doi.org/10.1200/JCO.2010.34.2014DOI Listing
June 2011

Enhanced mammary progesterone receptor-A isoform activity in the promotion of mammary tumor progression by dietary soy in rats.

Nutr Cancer 2010 ;62(6):774-82

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, and Arkansas Children's Nutrition Center, Little Rock, AR 72202, USA.

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http://dx.doi.org/10.1080/01635581.2010.494334DOI Listing
November 2010

Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer.

J Mammary Gland Biol Neoplasia 2010 Jun 31;15(2):253-60. Epub 2010 Mar 31.

Dan L. Duncan Cancer Center Division of Biostatistics, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10911-010-9173-1DOI Listing
June 2010

Pharmacogenetics of breast cancer: toward the individualization of therapy.

Cancer Invest 2009 Aug;27(7):699-703

Breast Center, Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1080/07357900903152473DOI Listing
August 2009

HER2 inhibition: from discovery to clinical practice.

Authors:
Jenny C Chang

Clin Cancer Res 2007 Jan;13(1):1-3

Breast Center, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2405DOI Listing
January 2007

Molecular heterogeneity of inflammatory breast cancer: a hyperproliferative phenotype.

Clin Cancer Res 2006 Sep;12(17):5047-54

Breast Center, Baylor College of Medicine and the Methodist Hospital, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-2248DOI Listing
September 2006

Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (cytoxan) (AC) response and resistance.

Breast Cancer Res Treat 2006 Feb;95(3):229-33

Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1007/s10549-005-9009-7DOI Listing
February 2006

Clinical response to neoadjuvant docetaxel predicts improved outcome in patients with large locally advanced breast cancers.

Breast Cancer Res Treat 2005 Dec;94(3):279-84

Breast Center and the Department of Medicine, Baylor College of Medicine and the Methodist Hospital, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10549-005-9020-zDOI Listing
December 2005

Apoptosis induction by the core biopsy procedure.

J Clin Oncol 2005 Oct;23(28):7240

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http://dx.doi.org/10.1200/JCO.2005.02.5197DOI Listing
October 2005

The promise of microarrays in the management and treatment of breast cancer.

Breast Cancer Res 2005 1;7(3):100-4. Epub 2005 Apr 1.

Breast Center, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1186/bcr1018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143565PMC
January 2006

Neoadjuvant trastuzumab induces apoptosis in primary breast cancers.

J Clin Oncol 2005 Apr 14;23(11):2460-8. Epub 2005 Feb 14.

Breast Center at Baylor College of Medicine/The Methodist Hospital, 1 Baylor Plaza, MS 600, Houston, TX 77030, USA.

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http://dx.doi.org/10.1200/JCO.2005.00.661DOI Listing
April 2005

Genomic approaches to understanding and treating breast cancer.

Breast Dis 2004 ;19:35-46

Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.3233/bd-2004-19106DOI Listing
March 2005

Neoadjuvant trastuzumab and docetaxel in breast cancer: preliminary results.

Clin Breast Cancer 2003 Dec;4(5):348-53

Department of Surgery, Methodist Hospital, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.3816/cbc.2003.n.040DOI Listing
December 2003

Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer.

Lancet 2003 Aug;362(9381):362-9

Breast Center and the Departments of Medicine, Pathology, and Molecular and Cellular Biology, Baylor College of Medicine, and the Methodist Hospital, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/S0140-6736(03)14023-8DOI Listing
August 2003