Jennifer Wargo

Jennifer Wargo

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Jennifer Wargo

Jennifer Wargo

Publications by authors named "Jennifer Wargo"

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Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes.

Cell 2019 Aug;178(4):795-806.e12

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Clinical Cancer Genetics Program, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.008DOI Listing
August 2019

Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy.

Front Immunol 2018 4;9:946. Epub 2018 May 4.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945998PMC
July 2019

The Current Landscape of Immune Checkpoint Inhibition for Solid Malignancies.

Surg Oncol Clin N Am 2019 Jul;28(3):369-386

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1484, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.soc.2019.02.008DOI Listing
July 2019

Neoadjuvant therapy for melanoma: is it ready for prime time?

Lancet Oncol 2019 Jul 3;20(7):892-894. Epub 2019 Jun 3.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 77030; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 77030. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30377-8DOI Listing
July 2019

The cancer microbiome.

Nat Rev Cancer 2019 07 11;19(7):371-376. Epub 2019 Jun 11.

Department of Surgical Oncology and Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41568-019-0155-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700740PMC
July 2019

Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3 Regulatory T Cells (Tregs) in Human Cancers-Response.

Clin Cancer Res 2019 Jun;25(11):3469-3470

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662573PMC
June 2019

Role of Immune Response, Inflammation, and Tumor Immune Response-Related Cytokines/Chemokines in Melanoma Progression.

J Invest Dermatol 2019 Jun 7. Epub 2019 Jun 7.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.03.1158DOI Listing
June 2019

Immunotherapy resistance: the answers lie ahead - not in front - of us.

J Immunother Cancer 2017 21;5:10. Epub 2017 Feb 21.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit Number 1484, Houston, TX 77030 USA.

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http://dx.doi.org/10.1186/s40425-017-0212-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319188PMC
March 2019

A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITF /AXL melanoma.

Pigment Cell Melanoma Res 2019 03 19;32(2):280-291. Epub 2018 Oct 19.

Manchester Cancer Research Centre, Faculty of Biology, Medicine & Health, Division of Cancer Sciences, The University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1111/pcmr.12741
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http://dx.doi.org/10.1111/pcmr.12741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392120PMC
March 2019

The microbiome, cancer, and cancer therapy.

Nat Med 2019 03 6;25(3):377-388. Epub 2019 Mar 6.

Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41591-019-0377-7DOI Listing
March 2019

Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3 Regulatory T Cells (Tregs) in Human Cancers.

Clin Cancer Res 2019 Feb 27;25(4):1233-1238. Epub 2018 Jul 27.

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-18-0762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348141PMC
February 2019

Modulating the microbiome to improve therapeutic response in cancer.

Lancet Oncol 2019 Feb;20(2):e77-e91

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(18)30952-5DOI Listing
February 2019

The Impact of Intratumoral and Gastrointestinal Microbiota on Systemic Cancer Therapy.

Trends Immunol 2018 11;39(11):900-920

Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA; These authors contributed equally to this work. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714906183017
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http://dx.doi.org/10.1016/j.it.2018.09.007DOI Listing
November 2018

The Rationale and Emerging Use of Neoadjuvant Immune Checkpoint Blockade for Solid Malignancies.

Ann Surg Oncol 2018 Jul 2;25(7):1814-1827. Epub 2018 Mar 2.

Department of Surgical Oncology and Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://link.springer.com/10.1245/s10434-018-6379-8
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http://dx.doi.org/10.1245/s10434-018-6379-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105272PMC
July 2018

High expression of PD-1 and PD-L1 in ocular adnexal sebaceous carcinoma.

Oncoimmunology 2018 26;7(9):e1475874. Epub 2018 Jul 26.

Department of Pathology, Section of Dermatopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1080/2162402X.2018.1475874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140585PMC
July 2018

Immune Checkpoint Blockade across the Cancer Care Continuum.

Immunity 2018 06;48(6):1077-1080

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.06.003DOI Listing
June 2018

Combination Immunotherapy Development in Melanoma.

Am Soc Clin Oncol Educ Book 2018 May;38:197-207

From the Gustave Roussy Cancer Institute and University Paris-Saclay, Villejuif, France; Earle A. Chiles Research Institute, Portland, OR; The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/EDBK_201131DOI Listing
May 2018

The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy.

Cancer Cell 2018 04;33(4):570-580

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit Number 1484, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Unit 1954, 1881 East Road, Houston, Texas 77054, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529202PMC
April 2018

Linking Associations of Rare Low-Abundance Species to Their Environments by Association Networks.

Front Microbiol 2018 7;9:297. Epub 2018 Mar 7.

Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.3389/fmicb.2018.00297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850922PMC
March 2018

Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade.

Cell 2017 Sep 10;170(6):1120-1133.e17. Epub 2017 Aug 10.

Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Parker Institute for Cancer Immunotherapy, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591072PMC
September 2017

Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes.

J Invest Dermatol 2017 08 23;137(8):1792-1795. Epub 2017 Apr 23.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2017.04.007DOI Listing
August 2017

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.

J Exp Med 2017 06 27;214(6):1691-1710. Epub 2017 Apr 27.

Manchester Cancer Research Centre, Faculty of Biology, Medicine, and Health, School of Medical Sciences, Division of Molecular and Clinical Cancer Studies, The University of Manchester, Manchester M13 9PT, England, UK

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http://dx.doi.org/10.1084/jem.20160855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460994PMC
June 2017

Hallmarks of response to immune checkpoint blockade.

Br J Cancer 2017 Jun 18;117(1):1-7. Epub 2017 May 18.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/bjc.2017.136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520201PMC
June 2017

Interaction of molecular alterations with immune response in melanoma.

Cancer 2017 06;123(S11):2130-2142

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cncr.30681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105277PMC
June 2017

Diverse types of dermatologic toxicities from immune checkpoint blockade therapy.

J Cutan Pathol 2017 Feb 21;44(2):158-176. Epub 2016 Dec 21.

Department of Pathology, Section of Dermatopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1111/cup.12858DOI Listing
February 2017

Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy.

Cell 2017 02;168(4):707-723

Department of Medicine, Division of Hematology-Oncology, University of California, Los Angeles and the Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391692PMC
February 2017

Targeted Therapies Combined With Immune Checkpoint Therapy.

Cancer J 2016 Mar-Apr;22(2):138-46

From the Departments of *Surgical Oncology and †Genomic Medicine, University of Texas M. D. Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1097/PPO.0000000000000182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478395PMC
January 2017

Gene Targeting Meets Cell-Based Therapy: Raising the Tail, or Merely a Whimper?

Clin Cancer Res 2017 Jan 11;23(2):327-329. Epub 2016 Nov 11.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241203PMC
January 2017

Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma.

Mol Cancer Ther 2016 10 25;15(10):2442-2454. Epub 2016 Jul 25.

Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079683PMC
http://dx.doi.org/10.1158/1535-7163.MCT-15-0963DOI Listing
October 2016

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.

Cell 2016 Oct 22;167(2):397-404.e9. Epub 2016 Sep 22.

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088716PMC
http://dx.doi.org/10.1016/j.cell.2016.08.069DOI Listing
October 2016

Uveal melanoma: From diagnosis to treatment and the science in between.

Cancer 2016 08 15;122(15):2299-312. Epub 2016 Mar 15.

Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cncr.29727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567680PMC
August 2016

Monitoring immune responses in the tumor microenvironment.

Curr Opin Immunol 2016 08 27;41:23-31. Epub 2016 May 27.

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Unit 1374, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2016.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257261PMC
August 2016

Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy.

Curr Oncol Rep 2016 07;18(7):42

Department of Surgical Oncology, Genomic Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s11912-016-0531-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330383PMC
July 2016

Association of Vitamin D Levels With Outcome in Patients With Melanoma After Adjustment For C-Reactive Protein.

J Clin Oncol 2016 05 21;34(15):1741-7. Epub 2016 Mar 21.

Shenying Fang, Dawen Sui, Yuling Wang, Huey Liu, Yi-Ju Chiang, Merrick I. Ross, Jeffrey E. Gershenwald, Janice N. Cormier, Richard E. Royal, Anthony Lucci, Jennifer Wargo, Mimi I. Hu, Julie M. Gardner, Roland L. Bassett, and Jeffrey E. Lee, The University of Texas MD Anderson Cancer Center; John D. Reveille, The University of Texas Health Science Center at Houston, Houston, TX; Qingyi Wei, Duke University School of Medicine, Durham, NC; and Christopher I. Amos, Dartmouth College, Lebanon, NH

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http://dx.doi.org/10.1200/JCO.2015.64.1357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966337PMC
May 2016

Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy.

Cancer Cell 2016 Mar;29(3):270-284

Manchester Cancer Research Centre, Wellcome Trust Centre for Cell-Matrix Research, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796027PMC
March 2016

Human melanoma immunotherapy using tumor antigen-specific T cells generated in humanized mice.

Oncotarget 2016 Feb;7(6):6448-59

The First Bethune Hospital and Institute of Immunology, Jilin University, Changchun, China.

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http://dx.doi.org/10.18632/oncotarget.7044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872726PMC
February 2016

Novel Treatments in Development for Melanoma.

Cancer Treat Res 2016 ;167:371-416

University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-3-319-22539-5_16DOI Listing
January 2016

Working with Human Tissues for Translational Cancer Research.

J Vis Exp 2015 Nov 26(105). Epub 2015 Nov 26.

Department of Surgical Oncology, University of Texas MD Anderson Cancer Center;

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http://dx.doi.org/10.3791/53189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692755PMC
November 2015

Raising the bar: optimizing combinations of targeted therapy and immunotherapy.

Ann Transl Med 2015 Oct;3(18):272

1 Department of Surgical Oncology; 2 Department of Genomic Medicine, the University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.3978/j.issn.2305-5839.2015.10.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630548PMC
October 2015