Jennifer S Yokoyama

Jennifer S Yokoyama

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Jennifer S Yokoyama

Publications by authors named "Jennifer S Yokoyama"

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The Radiogenomics of Late-onset Alzheimer Disease.

Top Magn Reson Imaging 2019 Dec;28(6):325-334

Department of Neurology, University of California, San Francisco, CA.

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http://dx.doi.org/10.1097/RMR.0000000000000222DOI Listing
December 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 Jun 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
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http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145PMC
June 2019

The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease.

Front Immunol 2019 4;10:1170. Epub 2019 Jun 4.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.

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http://dx.doi.org/10.3389/fimmu.2019.01170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557985PMC
June 2019

Immunological signatures in frontotemporal lobar degeneration.

Curr Opin Neurol 2019 04;32(2):272-278

Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1097/WCO.0000000000000665DOI Listing
April 2019

Recent advances in the genetics of frontotemporal dementia.

Curr Genet Med Rep 2019 Mar 30;7(1):41-52. Epub 2019 Jan 30.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1007/s40142-019-0160-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827567PMC
March 2019

C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies.

Acta Neuropathol 2019 01 27;137(1):1-26. Epub 2018 Oct 27.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, USA.

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http://link.springer.com/10.1007/s00401-018-1921-0
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http://dx.doi.org/10.1007/s00401-018-1921-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546170PMC
January 2019

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD.

Neurol Genet 2018 Oct 1;4(5):e266. Epub 2018 Oct 1.

Department of Neurology (L.W.B., N.Z.R.S., E.G.G., Z.A.M., B.L.M., W.W.S., J.S.Y.), Memory and Aging Center, University of California, San Francisco; Department of Psychiatry (C.M.K., N.W., A.O.-K.), Washington University, St. Louis, MO; School of Pharmacy (C.M., P.L.), University of Reading, Reading, UK; Laboratory of Neurogenetics (P.M.), Texas Tech University Health Science Center, Lubbock; Department of Molecular Neuroscience (C.M., J.H., P.L., R.F.), UCL Institute of Neurology, London, UK; Department of Radiology and Biomedical Imaging, Neuroradiology Section (C.P.H., R.S.D.), University of California, San Francisco; and Department of Neurology (S.E.B.), University of California, San Francisco.

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http://ng.neurology.org/lookup/doi/10.1212/NXG.0000000000000
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http://dx.doi.org/10.1212/NXG.0000000000000266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167176PMC
October 2018

Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer's Disease.

Front Neurosci 2018 7;12:529. Epub 2018 Aug 7.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, United States.

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http://dx.doi.org/10.3389/fnins.2018.00529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090298PMC
August 2018

Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes.

Am J Alzheimers Dis Other Demen 2018 05 16;33(3):153-165. Epub 2018 Jan 16.

1 Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1533317517739384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098PMC
May 2018

Genome-wide association study identifies locus influencing human plasma tau levels.

Neurology 2017 Feb 18;88(7):669-676. Epub 2017 Jan 18.

From the Department of Neurology (J.C., K.W., G.C.), David Geffen School of Medicine, and Memory and Aging Center (J.S.Y., J.H.K., H.R., B.L.M., A.L.B.), Department of Neurology, University of California, Los Angeles; Department of Neurology (J.-T.Y., H.-F.W.), Qingdao Municipal Hospital, Nanjing Medical University, China; Clinical Neurochemistry Laboratory (H.Z., K.B.), Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg Mölndal, Sweden; Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology, London, UK; and Center for Imaging of Neurodegenerative Diseases (M.W.W.), VAMC San Francisco, CA.

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http://dx.doi.org/10.1212/WNL.0000000000003615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317386PMC
February 2017

Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture.

Neurol Neuroimmunol Neuroinflamm 2016 Dec 28;3(6):e301. Epub 2016 Oct 28.

Memory and Aging Center (Z.A.M., V.E.S., A.K., J.S.Y., L.T.G., A.L.B., H.J.R., K.P.R., M.L.G.-T., W.W.S., B.L.M.) and Department of Pathology (L.T.G., W.W.S.), University of California, San Francisco; Departments of Neurology (G.B.C., N.R.G.-R.) and Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL; and Department of Neurology (G.C., D.H.G.), David Geffen School of Medicine, University of California, Los Angeles, CA.

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http://dx.doi.org/10.1212/NXI.0000000000000301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087253PMC
December 2016

Association of Alzheimer Disease Susceptibility Variants and Gene Expression in the Human Brain-Reply.

JAMA Neurol 2016 10;73(10):1255

Neuroradiology Section, Department of Radiology and Biomedical Imaging, University of California, San Francisco.

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http://dx.doi.org/10.1001/jamaneurol.2016.2799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140007PMC
October 2016

Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression.

Acta Neuropathol Commun 2016 09 2;4(1):98. Epub 2016 Sep 2.

Memory and Aging Center, UCSF, Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1186/s40478-016-0367-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010724PMC
September 2016

APOE Genotype Affects Cognitive Training Response in Healthy Shanghai Community-Dwelling Elderly Individuals.

J Alzheimers Dis 2015 ;47(4):1035-46

Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China.

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http://dx.doi.org/10.3233/JAD-150039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799000PMC
July 2016

The relationship between complement factor C3, APOE ε4, amyloid and tau in Alzheimer's disease.

Acta Neuropathol Commun 2016 06 29;4(1):65. Epub 2016 Jun 29.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1186/s40478-016-0339-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928261PMC
June 2016

Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.

Age (Dordr) 2016 Apr 22;38(2):41. Epub 2016 Mar 22.

Departments of Psychiatry, Neurology, and Epidemiology and Biostatistics, University of California - San Francisco, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, Box 181, San Francisco, CA, 94121, USA.

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http://dx.doi.org/10.1007/s11357-016-9885-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889PMC
April 2016

The Chinese Verbal Learning Test specifically assesses hippocampal state.

Am J Alzheimers Dis Other Demen 2015 Jun 30;30(4):412-6. Epub 2014 Sep 30.

Department of Neurology, University of California San Francisco, San Francisco, CA, USA UCSF Memory and Aging Center, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1533317514552667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379122PMC
June 2015

Variation in longevity gene KLOTHO is associated with greater cortical volumes.

Ann Clin Transl Neurol 2015 Mar 26;2(3):215-30. Epub 2015 Jan 26.

Department of Neurology, University of California San Francisco San Francisco, California, 94158.

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http://dx.doi.org/10.1002/acn3.161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369272PMC
March 2015

Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer's disease.

BMC Neurol 2015 Mar 28;15:47. Epub 2015 Mar 28.

Semel Institute for Neuroscience and Human Behavior, Departments of Neurology and Psychiatry, The David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1186/s12883-015-0304-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459447PMC
March 2015

Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion.

Brain 2014 Nov 1;137(Pt 11):3047-60. Epub 2014 Oct 1.

1 Memory and Ageing Centre, Department of Neurology, University of California, San Francisco, CA 94158, USA 6 Department of Pathology, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1093/brain/awu248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208465PMC
November 2014

Genetic modifiers of cognitive maintenance among older adults.

Hum Brain Mapp 2014 Sep 10;35(9):4556-65. Epub 2014 Mar 10.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, California.

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http://dx.doi.org/10.1002/hbm.22494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107001PMC
September 2014

Depressive symptoms in Chinese-American subjects with cognitive impairment.

Am J Geriatr Psychiatry 2014 Jul 8;22(7):642-52. Epub 2013 Sep 8.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2012.10.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309267PMC
July 2014

Neuroimaging features of C9ORF72 expansion.

Alzheimers Res Ther 2012 16;4(6):45. Epub 2012 Nov 16.

Memory and Aging Center, Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, Box 1207, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1186/alzrt148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580454PMC
June 2014

C9ORF72 hexanucleotide repeats in behavioral and motor neuron disease: clinical heterogeneity and pathological diversity.

Am J Neurodegener Dis 2014 28;3(1):1-18. Epub 2014 Mar 28.

Department of Neurology, University of California San Francisco, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986607PMC
June 2014

Life extension factor klotho enhances cognition.

Cell Rep 2014 May 10;7(4):1065-76. Epub 2014 May 10.

Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176932PMC
May 2014

Heightened emotional contagion in mild cognitive impairment and Alzheimer's disease is associated with temporal lobe degeneration.

Proc Natl Acad Sci U S A 2013 Jun 28;110(24):9944-9. Epub 2013 May 28.

Memory and Aging Center, Department of Neurology, Sandler Neurosciences Center, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1073/pnas.1301119110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683715PMC
June 2013

Variation in genes related to cochlear biology is strongly associated with adult-onset deafness in border collies.

PLoS Genet 2012 Sep 13;8(9):e1002898. Epub 2012 Sep 13.

Department of Psychiatry and Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1002898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441646PMC
September 2012

Array-based whole-genome survey of dog saliva DNA yields high quality SNP data.

PLoS One 2010 May 25;5(5):e10809. Epub 2010 May 25.

Department of Psychiatry and Institute for Human Genetics, University of California San Francisco, San Francisco, California, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010809PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876042PMC
May 2010

A genomewide association study of citalopram response in major depressive disorder.

Biol Psychiatry 2010 Jan;67(2):133-8

Department of Psychiatry and Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143-0984, USA.

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http://dx.doi.org/10.1016/j.biopsych.2009.08.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794921PMC
January 2010