Publications by authors named "Jennifer Mathieu"

27 Publications

  • Page 1 of 1

Rapid Treatment with Intramuscular Magnesium Sulfate During Cardiopulmonary Resuscitation Does Not Provide Neuroprotection Following Cardiac Arrest.

Mol Neurobiol 2022 Jan 14. Epub 2022 Jan 14.

Department of Emergency Medicine, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.

Brain injury is the most common cause of death for patients resuscitated from cardiac arrest. Magnesium is an attractive neuroprotective compound which protects neurons from ischemic injury by reducing neuronal calcium overload via NMDA receptor modulation and preventing calcium-induced mitochondrial permeability transition. Intramuscular (IM) delivery of MgSO during CPR has the potential to target these mechanisms within an early therapeutic window. We hypothesize that IM MgSO administrated during CPR could achieve therapeutic serum magnesium levels within 15 min after ROSC and improve neurologic outcomes in a rat model of asphyxial cardiac arrest. Male Long Evans rats were subjected to 8-min asphyxial cardiac arrest and block randomized to receive placebo, 107 mg/kg, 215 mg/kg, or 430 mg/kg MgSO IM at the onset of CPR. Serum magnesium concentrations increased rapidly with IM delivery during CPR, achieving twofold to fourfold increase by 15 min after ROSC in all magnesium dose groups. Rats subjected to cardiac arrest or sham surgery were block randomized to treatment groups for assessment of neurological outcomes. We found that IM MgSO during CPR had no effect on ROSC rate (p > 0.05). IM MgSO treatment had no statistically significant effect on 10-day survival with good neurologic function or hippocampal CA1 pyramidal neuron survival compared to placebo treatment. In conclusion, a single dose IM MgSO during CPR achieves up to fourfold baseline serum magnesium levels within 15 min after ROSC; however, this treatment strategy did not improve survival, recovery of neurologic function, or neuron survival. Future studies with repeated dosing or in combination with hypothermic targeted temperature management may be indicated.
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http://dx.doi.org/10.1007/s12035-021-02645-xDOI Listing
January 2022

COVID-19 Vaccine Discourse on Twitter: A Content Analysis of Persuasion Techniques, Sentiment and Mis/Disinformation.

J Health Commun 2021 07 4;26(7):443-459. Epub 2021 Aug 4.

Health Innovation Center, The MITRE Corporation, McLean, Virginia, USA.

This research aims to understand the persuasion techniques used in Twitter posts about COVID-19 vaccines by the different vaccine sentiments (i.e., Pro-Vaccine, Anti-Vaccine, and Neutral) using the Elaboration Likelihood Model, Social judgment Theory, and the Extended Parallel Process Model as theoretical frameworks. A content analysis was conducted on a data set of 1,000 Twitter posts. The corpus of Tweets was examined using the persuasion frameworks; tweets that were identified as emanating from bots were further examined. Results found Anti-Vaccine messages predominantly used Anecdotal stories, Humor/Sarcasm, and Celebrity figures as persuasion techniques, while Pro-Vaccine messages primarily used Information, Celebrity figures, and Participation. Results also showed the Anti-Vaccine messages primarily focused on values related to the categories of Safety, Political/Conspiracy Theories, and Choice. Finally, results revealed Anti-Vaccine messages primarily used Perceived Severity and Perceived Susceptibility, which are fear appeal elements. The findings for messages by bots were comparable to the messages in the larger corpus of tweets. Based on the findings, a response framework-Health Information Persuasion Exploration (HIPE)-is proposed to address mis/disinformation and Anti-Vaccine messaging. The results of this study and the HIPE framework can inform a national COVID-19 vaccine health campaign to increase vaccine adoption.
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http://dx.doi.org/10.1080/10810730.2021.1955050DOI Listing
July 2021

COVID-19 Vaccine Discourse on Twitter: A Content Analysis of Persuasion Techniques, Sentiment and Mis/Disinformation.

J Health Commun 2021 07 4;26(7):443-459. Epub 2021 Aug 4.

Health Innovation Center, The MITRE Corporation, McLean, Virginia, USA.

This research aims to understand the persuasion techniques used in Twitter posts about COVID-19 vaccines by the different vaccine sentiments (i.e., Pro-Vaccine, Anti-Vaccine, and Neutral) using the Elaboration Likelihood Model, Social judgment Theory, and the Extended Parallel Process Model as theoretical frameworks. A content analysis was conducted on a data set of 1,000 Twitter posts. The corpus of Tweets was examined using the persuasion frameworks; tweets that were identified as emanating from bots were further examined. Results found Anti-Vaccine messages predominantly used Anecdotal stories, Humor/Sarcasm, and Celebrity figures as persuasion techniques, while Pro-Vaccine messages primarily used Information, Celebrity figures, and Participation. Results also showed the Anti-Vaccine messages primarily focused on values related to the categories of Safety, Political/Conspiracy Theories, and Choice. Finally, results revealed Anti-Vaccine messages primarily used Perceived Severity and Perceived Susceptibility, which are fear appeal elements. The findings for messages by bots were comparable to the messages in the larger corpus of tweets. Based on the findings, a response framework-Health Information Persuasion Exploration (HIPE)-is proposed to address mis/disinformation and Anti-Vaccine messaging. The results of this study and the HIPE framework can inform a national COVID-19 vaccine health campaign to increase vaccine adoption.
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http://dx.doi.org/10.1080/10810730.2021.1955050DOI Listing
July 2021

Moving into management.

Authors:
Jennifer Mathieu

J Acad Nutr Diet 2012 May 20;112(5 Suppl):S16-7. Epub 2012 Apr 20.

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http://dx.doi.org/10.1016/j.jand.2012.03.017DOI Listing
May 2012

A model-based tool to predict the propagation of infectious disease via airports.

Travel Med Infect Dis 2012 Jan 14;10(1):32-42. Epub 2012 Jan 14.

The MITRE Corporation, 2275 Rolling Run Drive, Woodlawn, MD 21244, USA.

Epidemics of novel or re-emerging infectious diseases have quickly spread globally via air travel, as highlighted by pandemic H1N1 influenza in 2009 (pH1N1). Federal, state, and local public health responders must be able to plan for and respond to these events at aviation points of entry. The emergence of a novel influenza virus and its spread to the United States were simulated for February 2009 from 55 international metropolitan areas using three basic reproduction numbers (R(0)): 1.53, 1.70, and 1.90. Empirical data from the pH1N1 virus were used to validate our SEIR model. Time to entry to the U.S. during the early stages of a prototypical novel communicable disease was predicted based on the aviation network patterns and the epidemiology of the disease. For example, approximately 96% of origins (R(0) of 1.53) propagated a disease into the U.S. in under 75 days, 90% of these origins propagated a disease in under 50 days. An R(0) of 1.53 reproduced the pH1NI observations. The ability to anticipate the rate and location of disease introduction into the U.S. provides greater opportunity to plan responses based on the scenario as it is unfolding. This simulation tool can aid public health officials to assess risk and leverage resources efficiently.
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http://dx.doi.org/10.1016/j.tmaid.2011.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185572PMC
January 2012

Revamping your resume for your specialty.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2010 Mar;110(3):353-60

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http://dx.doi.org/10.1016/j.jada.2010.01.004DOI Listing
March 2010

What should you know about mindful and intuitive eating?

Authors:
Jennifer Mathieu

J Am Diet Assoc 2009 Dec;109(12):1982-7

Northwestern University, USA.

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http://dx.doi.org/10.1016/j.jada.2009.10.023DOI Listing
December 2009

What is pregorexia?

Authors:
Jennifer Mathieu

J Am Diet Assoc 2009 Jun;109(6):976-9

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http://dx.doi.org/10.1016/j.jada.2009.04.021DOI Listing
June 2009

Marketing yourself and taking risks.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2009 Jan;109(1):28-9

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http://dx.doi.org/10.1016/j.jada.2008.11.011DOI Listing
January 2009

RDs in the Military.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2008 Dec;108(12):1984, 1986-7

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http://dx.doi.org/10.1016/j.jada.2008.10.038DOI Listing
December 2008

Consulting do's and don'ts.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2008 Nov;108(11):1827-8

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http://dx.doi.org/10.1016/j.jada.2008.09.024DOI Listing
November 2008

Moving into management.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2008 Sep;108(9):1423, 1425

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http://dx.doi.org/10.1016/j.jada.2008.07.023DOI Listing
September 2008

Safe play and its effect on childhood obesity.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2008 May;108(5):774-5

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http://dx.doi.org/10.1016/j.jada.2008.03.028DOI Listing
May 2008

Research resources at your fingertips.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2008 Mar;108(3):428-9

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http://dx.doi.org/10.1016/j.jada.2008.01.033DOI Listing
March 2008

Sifting through the research on supplements.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2007 Jun;107(6):912-4

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http://dx.doi.org/10.1016/j.jada.2007.04.019DOI Listing
June 2007

Tips for publishing a top-notch newsletter.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2007 Mar;107(3):384-5

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http://dx.doi.org/10.1016/j.jada.2007.01.017DOI Listing
March 2007

Hey everyone, dinner's ready...two weeks ago!

Authors:
Jennifer Mathieu

J Am Diet Assoc 2007 Jan;107(1):26-7

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http://dx.doi.org/10.1016/j.jada.2006.10.008DOI Listing
January 2007

Getting that First Job: Tips for the Interview.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2006 Oct;106(10):1546-8

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http://dx.doi.org/10.1016/j.jada.2006.07.019DOI Listing
October 2006

Getting that first job: search and resume tips.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2006 Sep;106(9):1338, 1340, 1342-5

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http://dx.doi.org/10.1016/j.jada.2006.07.025DOI Listing
September 2006

What is orthorexia?

Authors:
Jennifer Mathieu

J Am Diet Assoc 2005 Oct;105(10):1510-2

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http://dx.doi.org/10.1016/j.jada.2005.08.021DOI Listing
October 2005

Herbs and cancer treatment.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2005 Jan;105(1):22-3

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http://dx.doi.org/10.1016/j.jada.2004.11.012DOI Listing
January 2005

Disordered eating across the life span.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2004 Aug;104(8):1208-10

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http://dx.doi.org/10.1016/j.jada.2004.06.009DOI Listing
August 2004

Community-based dietetics professionals.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2003 Sep;103(9):1127-8

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http://dx.doi.org/10.1016/s0002-8223(03)01081-2DOI Listing
September 2003

Food safety and home delivery.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2002 Dec;102(12):1744, 1746

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http://dx.doi.org/10.1016/s0002-8223(02)90370-6DOI Listing
December 2002

NSI: providing simple tools for our nation's health.

Authors:
Jennifer Mathieu

J Am Diet Assoc 2002 Oct;102(10):1394

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http://dx.doi.org/10.1016/s0002-8223(02)90304-4DOI Listing
October 2002
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