Jennifer L Cannons

Jennifer L Cannons

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Jennifer L Cannons

Jennifer L Cannons

Publications by authors named "Jennifer L Cannons"

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Genetic Defects in Phosphoinositide 3-Kinase δ Influence CD8 T Cell Survival, Differentiation, and Function.

Front Immunol 2018 2;9:1758. Epub 2018 Aug 2.

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01758
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http://dx.doi.org/10.3389/fimmu.2018.01758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082933PMC
October 2019

T and B-cell signaling in activated PI3K delta syndrome: From immunodeficiency to autoimmunity.

Immunol Rev 2019 Sep;291(1):154-173

Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1111/imr.12790DOI Listing
September 2019

Mg regulation of kinase signaling and immune function.

J Exp Med 2019 Aug 13;216(8):1828-1842. Epub 2019 Jun 13.

Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

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http://dx.doi.org/10.1084/jem.20181970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683994PMC
August 2019

X-Linked Lymphoproliferative Disease Type 1: A Clinical and Molecular Perspective.

Front Immunol 2018 4;9:666. Epub 2018 Apr 4.

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, United States.

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http://journal.frontiersin.org/article/10.3389/fimmu.2018.00
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http://dx.doi.org/10.3389/fimmu.2018.00666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893764PMC
June 2019

PI3K Orchestrates T Follicular Helper Cell Differentiation in a Context Dependent Manner: Implications for Autoimmunity.

Front Immunol 2018 7;9:3079. Epub 2019 Jan 7.

National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, United States.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.03079
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http://dx.doi.org/10.3389/fimmu.2018.03079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330320PMC
January 2019

SAP and Lessons Learned from a Primary Immunodeficiency.

J Immunol 2017 09;199(5):1531-1533

Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892

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http://dx.doi.org/10.4049/jimmunol.1701007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582946PMC
September 2017

Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program.

J Immunol 2014 Mar 31;192(5):2156-66. Epub 2014 Jan 31.

Lymphocyte Biology Section, Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892;

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1300675
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http://dx.doi.org/10.4049/jimmunol.1300675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967131PMC
March 2014

Ncking BCR-mediated PI3K activation.

EMBO Rep 2013 Oct 23;14(10):852-3. Epub 2013 Aug 23.

National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/embor.2013.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807230PMC
October 2013

T follicular helper cell diversity and plasticity.

Trends Immunol 2013 May 8;34(5):200-7. Epub 2013 Feb 8.

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.cell.com/trends/immunology/pdf/S1471-4906(13)0000
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http://linkinghub.elsevier.com/retrieve/pii/S147149061300002
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http://dx.doi.org/10.1016/j.it.2013.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646926PMC
May 2013

Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis.

Immunity 2012 Jun 7;36(6):1003-16. Epub 2012 Jun 7.

Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10747613120023
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http://dx.doi.org/10.1016/j.immuni.2012.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389133PMC
June 2012

Lymph node choreography: B cells take the lead.

Nat Immunol 2012 Jun 19;13(7):630-2. Epub 2012 Jun 19.

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http://dx.doi.org/10.1038/ni.2349DOI Listing
June 2012

SLAM family receptors and SAP adaptors in immunity.

Annu Rev Immunol 2011 ;29:665-705

National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1146/annurev-immunol-030409-101302DOI Listing
June 2011

Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation.

J Immunol 2010 Sep 28;185(5):2819-27. Epub 2010 Jul 28.

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.0902182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422635PMC
September 2010

The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1).

J Exp Med 2009 Aug 27;206(8):1681-90. Epub 2009 Jul 27.

Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20082462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722182PMC
August 2009

Follicular helper T cells are required for systemic autoimmunity.

J Exp Med 2009 Mar 16;206(3):561-76. Epub 2009 Feb 16.

Division of Immunology and Genetics, The John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia.

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http://dx.doi.org/10.1084/jem.20081886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699132PMC
March 2009

SLAM receptors and SAP influence lymphocyte interactions, development and function.

Nat Rev Immunol 2009 Jan;9(1):39-46

National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nri2456DOI Listing
January 2009

The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death.

Nat Immunol 2008 Nov 21;9(11):1279-87. Epub 2008 Sep 21.

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ni.1653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580721PMC
November 2008

Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses.

J Immunol 2008 Nov;181(9):6125-31

Center for Molecular Immunology and Infectious Disease and Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849304PMC
http://dx.doi.org/10.4049/jimmunol.181.9.6125DOI Listing
November 2008

SAP-controlled T-B cell interactions underlie germinal centre formation.

Nature 2008 Oct;455(7214):764-9

Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nature07345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652134PMC
October 2008

Requirements for selection of conventional and innate T lymphocyte lineages.

Immunity 2007 Nov;27(5):775-85

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.immuni.2007.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377064PMC
November 2007

CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus.

Blood 2007 Apr 21;109(8):3432-40. Epub 2006 Dec 21.

Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, 49 Convent Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2006-10-051508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852246PMC
April 2007

Acinar cell apoptosis in Serpini2-deficient mice models pancreatic insufficiency.

PLoS Genet 2005 Sep;1(3):e38

Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1371/journal.pgen.0010038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1231717PMC
September 2005

Genetic and functional association of the immune signaling molecule 4-1BB (CD137/TNFRSF9) with type 1 diabetes.

J Autoimmun 2005 Aug;25(1):13-20

Department of Immunology, 1 King's College Circle, University of Toronto, Toronto, ON M5S 1A8, Canada.

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http://dx.doi.org/10.1016/j.jaut.2005.04.007DOI Listing
August 2005

Regulation of NKT cell development by SAP, the protein defective in XLP.

Nat Med 2005 Mar 13;11(3):340-5. Epub 2005 Feb 13.

Pediatric Oncology, Wood, 4th floor, 3615 Civic Center Boulevard, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/nm1189DOI Listing
March 2005

Molecular and cellular pathogenesis of X-linked lymphoproliferative disease.

Immunol Rev 2005 Feb;203:180-99

Pediatric Oncology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.0105-2896.2005.00230.xDOI Listing
February 2005

SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1.

Immunity 2004 Nov;21(5):693-706

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.immuni.2004.09.012DOI Listing
November 2004

Fine-tuning lymphocyte regulation: what's new with tyrosine kinases and phosphatases?

Curr Opin Immunol 2004 Jun;16(3):296-303

National Human Genome Research Institute, 49/4A38, 49 Convent Drive, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.coi.2004.03.011DOI Listing
June 2004

Cutting edge: profound defect in T cell responses in TNF receptor-associated factor 2 dominant negative mice.

J Immunol 2002 Sep;169(6):2828-31

Department of Immunology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.4049/jimmunol.169.6.2828DOI Listing
September 2002