Publications by authors named "Jennifer L Brogdon"

17Publications

Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas.

N Engl J Med 2017 12 10;377(26):2545-2554. Epub 2017 Dec 10.

From the Lymphoma Program at the Abramson Cancer Center and the Division of Hematology-Oncology (S.J.S., J.S., E.A.C., S.D.N., A.R.M., D.L., D.L.P.), and the Department of Pathology and Laboratory Medicine (V.B., M.W., B.L.L., S.F.L., J.J.M., C.H.J.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Novartis Pharmaceuticals, Basel, Switzerland (Ö.A.); and Novartis Institutes for BioMedical Research, Cambridge, MA (J.L.B., I.P-M.).

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http://www.nejm.org/doi/10.1056/NEJMoa1708566
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http://dx.doi.org/10.1056/NEJMoa1708566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788566PMC
December 2017

Rationale for anti-GITR cancer immunotherapy.

Eur J Cancer 2016 11 31;67:1-10. Epub 2016 Aug 31.

Department of Exploratory Immuno-Oncology, Novartis Institute for Biomedical Research, 250 Massachusetts Ave, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.06.028DOI Listing
November 2016

OX40 engagement depletes intratumoral Tregs via activating FcγRs, leading to antitumor efficacy.

Immunol Cell Biol 2014 Jul 15;92(6):475-80. Epub 2014 Apr 15.

Department of Oncology, Novartis Institute for Biomedical Research, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/icb.2014.26DOI Listing
July 2014

Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies.

J Exp Med 2013 Aug 29;210(9):1685-93. Epub 2013 Jul 29.

Department of Oncology and 2 Laboratory Animal Services, Novartis Institute for Biomedical Research, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1084/jem.20130573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754864PMC
August 2013

Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function.

Blood 2007 Feb 28;109(3):1123-30. Epub 2006 Sep 28.

Department of Developmental & Molecular Pathways, Novartis Institute for BioMedical Research, Cambridge, MA 02138, USA.

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http://dx.doi.org/10.1182/blood-2006-04-019711DOI Listing
February 2007

CD4-dependent signaling is required for a late checkpoint during Th2 development associated with resistance to activation-induced cell death.

J Immunol 2005 Nov;175(9):5629-36

Department of Immunology, The George Washington University, Washington, DC 20037, USA.

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http://dx.doi.org/10.4049/jimmunol.175.9.5629DOI Listing
November 2005

CD4 raft association and signaling regulate molecular clustering at the immunological synapse site.

J Immunol 2004 May;172(10):5887-92

Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.

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http://dx.doi.org/10.4049/jimmunol.172.10.5887DOI Listing
May 2004

Activation of CD4 T cells by Raf-independent effectors of Ras.

Proc Natl Acad Sci U S A 2003 May 29;100(10):6003-8. Epub 2003 Apr 29.

Section of Immunobiology, Department of Pathology, and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1073/pnas.1031494100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC156316PMC
May 2003

Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells.

J Immunol 2003 Mar;170(5):2427-34

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.4049/jimmunol.170.5.2427DOI Listing
March 2003

The potency of TCR signaling differentially regulates NFATc/p activity and early IL-4 transcription in naive CD4+ T cells.

J Immunol 2002 Apr;168(8):3825-32

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.4049/jimmunol.168.8.3825DOI Listing
April 2002