Jennifer Keiser

Jennifer Keiser

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Jennifer Keiser

Publications by authors named "Jennifer Keiser"

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Naturally Occurring Cardenolides Affecting .

ACS Infect Dis 2020 Jul 15;6(7):1922-1927. Epub 2020 May 15.

Institute of Organic Chemistry, Karlsruhe Institute of Technology, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany.

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http://dx.doi.org/10.1021/acsinfecdis.0c00175DOI Listing
July 2020

Parallelized Impedance-Based Platform for Continuous Dose-Response Characterization of Antischistosomal Drugs.

Adv Biosyst 2020 Jul 8;4(7):e1900304. Epub 2020 Jun 8.

Bioengineering Laboratory, Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, Basel, 4058, Switzerland.

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http://dx.doi.org/10.1002/adbi.201900304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354102PMC
July 2020

Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone.

J Antimicrob Chemother 2020 Jul 2. Epub 2020 Jul 2.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, PO Box, CH-4002, Basel, Switzerland.

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http://dx.doi.org/10.1093/jac/dkaa247DOI Listing
July 2020

Preparation, Physicochemical Characterization and In Vitro and In Vivo Activity Against Heligmosomoides polygyrus of Novel Oral Formulations of Albendazole and Mebendazole.

J Pharm Sci 2020 May 15;109(5):1819-1826. Epub 2020 Feb 15.

Swiss Tropical and Public Health Institute, Socinstrasse 57, P.O. Box CH-4002, Basel, Switzerland; University of Basel, Petersplatz 1, P.O. Box CH-4001, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.xphs.2020.02.002DOI Listing
May 2020

Synthesis, characterization and antiparasitic activity of organometallic derivatives of the anthelmintic drug albendazole.

Dalton Trans 2020 May;49(20):6616-6626

Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, 75005 Paris, France.

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http://dx.doi.org/10.1039/d0dt01107jDOI Listing
May 2020

Whipworm and roundworm infections.

Nat Rev Dis Primers 2020 May 28;6(1):44. Epub 2020 May 28.

Institute of Infection and Immunity, St George's University of London, London, UK.

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http://dx.doi.org/10.1038/s41572-020-0171-3DOI Listing
May 2020

Study of drug particle distributions within mini-tablets using synchrotron X-ray microtomography and superpixel image clustering.

Int J Pharm 2020 Jan 19;573:118827. Epub 2019 Nov 19.

Division of Pharmaceutical Technology, Department of Pharmaceutical Sciences, University of Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2019.118827DOI Listing
January 2020

A single dose of ivermectin is sufficient for strongyloidiasis.

Lancet Infect Dis 2019 11 23;19(11):1150-1151. Epub 2019 Sep 23.

Swiss Tropical and Public Health Institute, CH-4002 Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(19)30519-5DOI Listing
November 2019

Drug Combinations Against Soil-Transmitted Helminth Infections.

Adv Parasitol 2019 7;103:91-115. Epub 2018 Sep 7.

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/bs.apar.2018.08.002DOI Listing
October 2019

Exogenous Iron Increases Fasciocidal Activity and Hepatocellular Toxicity of the Synthetic Endoperoxides OZ78 and MT04.

Int J Mol Sci 2019 Oct 1;20(19). Epub 2019 Oct 1.

Division of Clinical Pharmacology & Toxicology, Department of Medicine, University of Basel, CH-4031 Basel, Switzerland.

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http://dx.doi.org/10.3390/ijms20194880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801819PMC
October 2019

Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery.

Parasit Vectors 2019 Oct 22;12(1):493. Epub 2019 Oct 22.

Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1186/s13071-019-3747-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805474PMC
October 2019

Ivermectin Dosing Strategy to Achieve Equivalent Exposure Coverage in Children and Adults.

Clin Pharmacol Ther 2019 09 25;106(3):661-667. Epub 2019 May 25.

University of Basel, Basel, Switzerland.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cpt.1456
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http://dx.doi.org/10.1002/cpt.1456DOI Listing
September 2019

Activity and pharmacokinetics of a praziquantel crystalline polymorph in the Schistosoma mansoni mouse model.

Eur J Pharm Biopharm 2019 Sep 29;142:240-246. Epub 2019 Jun 29.

Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4002 Basel, Switzerland; Universität Basel, Petersplatz 1, CH-4001 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2019.06.029DOI Listing
September 2019

Efficacy and Safety of Ascending Dosages of Tribendimidine Against Hookworm Infections in Children: A Randomized Controlled Trial.

Clin Infect Dis 2019 08;69(5):845-852

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.1093/cid/ciy999DOI Listing
August 2019

Reply to Nalin.

Clin Infect Dis 2019 07;69(2):376-377

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.1093/cid/ciy1015DOI Listing
July 2019

Pharmacokinetics of ascending doses of ivermectin in Trichuris trichiura-infected children aged 2-12 years.

J Antimicrob Chemother 2019 06;74(6):1642-1647

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.1093/jac/dkz083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524481PMC
June 2019

Community-wide soil-transmitted helminth treatment is equity-effective.

Lancet 2019 05 18;393(10185):2011-2012. Epub 2019 Apr 18.

Swiss Tropical and Public Health Institute, Basel CH-4002, Switzerland; University of Basel, Basel, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183298
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http://dx.doi.org/10.1016/S0140-6736(18)32981-7DOI Listing
May 2019

Evaluation of emodepside in laboratory models of human intestinal nematode and schistosome infections.

Parasit Vectors 2019 May 14;12(1):226. Epub 2019 May 14.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.1186/s13071-019-3476-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515646PMC
May 2019

Pharmacokinetics of Albendazole, Albendazole Sulfoxide, and Albendazole Sulfone Determined from Plasma, Blood, Dried-Blood Spots, and Mitra Samples of Hookworm-Infected Adolescents.

Antimicrob Agents Chemother 2019 04 27;63(4). Epub 2019 Mar 27.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland

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http://dx.doi.org/10.1128/AAC.02489-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437472PMC
April 2019

Novel 1-Methyl-1 H-pyrazole-5-carboxamide Derivatives with Potent Anthelmintic Activity.

J Med Chem 2019 04 28;62(7):3367-3380. Epub 2019 Mar 28.

School of Pharmaceutical Sciences , Nanjing Tech University , No. 30 South Puzhu Road , Nanjing 211816 , P. R. China.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01790DOI Listing
April 2019

Life cycle maintenance and drug-sensitivity assays for early drug discovery in Schistosoma mansoni.

Nat Protoc 2019 02;14(2):461-481

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://www.nature.com/articles/s41596-018-0101-y
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http://dx.doi.org/10.1038/s41596-018-0101-yDOI Listing
February 2019

and Drug-Drug Interaction Study of the Effects of Ivermectin and Oxantel Pamoate on Tribendimidine.

Antimicrob Agents Chemother 2019 01 21;63(1). Epub 2018 Dec 21.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland

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http://dx.doi.org/10.1128/AAC.00762-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325189PMC
January 2019

Early Antischistosomal Leads Identified from in Vitro and in Vivo Screening of the Medicines for Malaria Venture Pathogen Box.

ACS Infect Dis 2019 01 16;5(1):102-110. Epub 2018 Nov 16.

Department of Medical Parasitology and Infection Biology , Swiss Tropical and Public Health Institute , Basel , Switzerland.

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http://pubs.acs.org/doi/10.1021/acsinfecdis.8b00220
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http://dx.doi.org/10.1021/acsinfecdis.8b00220DOI Listing
January 2019

Off-target effects of tribendimidine, tribendimidine plus ivermectin, tribendimidine plus oxantel-pamoate, and albendazole plus oxantel-pamoate on the human gut microbiota.

Int J Parasitol Drugs Drug Resist 2018 12 2;8(3):372-378. Epub 2018 Jul 2.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/j.ijpddr.2018.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068340PMC
December 2018

SAR of a new antischistosomal urea carboxylic acid.

Bioorg Med Chem Lett 2018 12 25;28(23-24):3648-3651. Epub 2018 Oct 25.

College of Pharmacy, University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, NE, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.10.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301076PMC
December 2018

Impedance-Based Microfluidic Assay for Automated Antischistosomal Drug Screening.

ACS Sens 2018 12 28;3(12):2613-2620. Epub 2018 Nov 28.

Bio Engineering Laboratory, Dept. of Biosystems Science and Engineering , ETH Zurich , Basel , Switzerland.

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http://dx.doi.org/10.1021/acssensors.8b01027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396876PMC
December 2018

Assessment of tegumental damage to Schistosoma mansoni and S. haematobium after in vitro exposure to ferrocenyl, ruthenocenyl and benzyl derivatives of oxamniquine using scanning electron microscopy.

Parasit Vectors 2018 Nov 6;11(1):580. Epub 2018 Nov 6.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health institute, Socinstrasse 57, 4051, Basel, CH, Switzerland.

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3132-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219169PMC
November 2018

Synthesis, characterization and biological activity of organometallic derivatives of the antimalarial drug mefloquine as new antischistosomal drug candidates.

Medchemcomm 2018 Nov 10;9(11):1905-1909. Epub 2018 Oct 10.

Laboratory for Inorganic Chemical Biology , Chimie ParisTech , PSL University , F-75005 Paris , France . Email:

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http://dx.doi.org/10.1039/c8md00396cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256353PMC
November 2018

Acting beyond 2020: better characterization of praziquantel and promising antischistosomal leads.

Curr Opin Pharmacol 2018 10 1;42:27-33. Epub 2018 Aug 1.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, CH-4002 Basel, Switzerland; University of Basel, CH-4003 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2018.06.004DOI Listing
October 2018

Effects of Vancomycin and Ciprofloxacin on the NMRI Mouse Metabolism.

J Proteome Res 2018 10 20;17(10):3565-3573. Epub 2018 Sep 20.

Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine , Imperial College London , South Kensington Campus , London SW7 2AZ , United Kingdom.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00583
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http://dx.doi.org/10.1021/acs.jproteome.8b00583DOI Listing
October 2018

Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale.

J Pharmacokinet Pharmacodyn 2018 10 14;45(5):747-762. Epub 2018 Sep 14.

Swiss Tropical and Public Health Institute, Socinstr. 57, CH-4002, Basel, Switzerland.

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http://dx.doi.org/10.1007/s10928-018-9601-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182730PMC
October 2018

Efficacy and Safety of Ivermectin Against Trichuris trichiura in Preschool-aged and School-aged Children: A Randomized Controlled Dose-finding Trial.

Clin Infect Dis 2018 09;67(8):1247-1255

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute.

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http://dx.doi.org/10.1093/cid/ciy246DOI Listing
September 2018

Pharmacokinetics of a Pediatric Tribendimidine Dose-Finding Study To Treat Hookworm Infection in African Children.

Antimicrob Agents Chemother 2018 09 27;62(9). Epub 2018 Aug 27.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland

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http://dx.doi.org/10.1128/AAC.00959-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125550PMC
September 2018

Efficacy and tolerability of moxidectin alone and in co-administration with albendazole and tribendimidine versus albendazole plus oxantel pamoate against Trichuris trichiura infections: a randomised, non-inferiority, single-blind trial.

Lancet Infect Dis 2018 08 29;18(8):864-873. Epub 2018 May 29.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(18)30233-0DOI Listing
August 2018

Pharmacokinetics of Praziquantel in Schistosoma mansoni- and Schistosoma haematobium-Infected School- and Preschool-Aged Children.

Antimicrob Agents Chemother 2018 08 27;62(8). Epub 2018 Jul 27.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland

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http://dx.doi.org/10.1128/AAC.02253-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105791PMC
August 2018

Preventive Chemotherapy in the Fight against Soil-Transmitted Helminthiasis: Achievements and Limitations.

Trends Parasitol 2018 07 29;34(7):590-602. Epub 2018 May 29.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2018.04.008DOI Listing
July 2018

Efficacy and Safety of a Single Dose a Multiple Dose Regimen of Mebendazole against Hookworm Infections in Children: A Randomised, Double-blind Trial.

EClinicalMedicine 2018 Jul 11;1:7-13. Epub 2018 Jul 11.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/j.eclinm.2018.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537524PMC
July 2018

A new soluble and bioactive polymorph of praziquantel.

Eur J Pharm Biopharm 2018 Jun 31;127:19-28. Epub 2018 Jan 31.

Department of Pharmacy and BioTechnology, University of Bologna, Via S. Donato 19/2, 40127 Bologna, Italy.

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http://dx.doi.org/10.1016/j.ejpb.2018.01.018DOI Listing
June 2018

Characterizing the Biochemical Response to Schistosoma mansoni Infection and Treatment with Praziquantel in Preschool and School Aged Children.

J Proteome Res 2018 06 21;17(6):2028-2033. Epub 2018 May 21.

Division of Integrative Systems Medicine and Digestive Diseases , Department of Surgery and Cancer, Imperial College London , London SW7 2AZ , United Kingdom.

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http://dx.doi.org/10.1021/acs.jproteome.7b00910DOI Listing
June 2018

Diagnostic comparison between FECPAKG2 and the Kato-Katz method for analyzing soil-transmitted helminth eggs in stool.

PLoS Negl Trop Dis 2018 06 4;12(6):e0006562. Epub 2018 Jun 4.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel Switzerland.

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http://dx.doi.org/10.1371/journal.pntd.0006562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002127PMC
June 2018

Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni.

Parasit Vectors 2018 05 15;11(1):298. Epub 2018 May 15.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, P.O. Box, CH-4002, Basel, Switzerland.

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-2855-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952519PMC
May 2018

Retrospective assessment of resource use and costs in two investigator-initiated randomized trials exemplified a comprehensive cost item list.

J Clin Epidemiol 2018 04 30;96:73-83. Epub 2017 Dec 30.

Basel Institute for Clinical Epidemiology and Biostatistics, Department of Clinical Research, University of Basel and University Hospital Basel, Basel, Switzerland; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jclinepi.2017.12.022DOI Listing
April 2018

The optimal timing of post-treatment sampling for the assessment of anthelminthic drug efficacy against Ascaris infections in humans.

Int J Parasitol Drugs Drug Resist 2018 04 13;8(1):67-69. Epub 2018 Jan 13.

Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

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http://dx.doi.org/10.1016/j.ijpddr.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114078PMC
April 2018

Egg Excretion does not Increase after Exercise: Implications for Diagnostic Testing.

Am J Trop Med Hyg 2018 03 14;98(3):772-775. Epub 2017 Dec 14.

Divisions of General Internal Medicine and Infectious Diseases, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.17-0728
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http://dx.doi.org/10.4269/ajtmh.17-0728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930907PMC
March 2018

Evaluation of a novel micro-sampling device, Mitra™, in comparison to dried blood spots, for analysis of praziquantel in Schistosoma haematobium-infected children in rural Côte d'Ivoire.

J Pharm Biomed Anal 2018 Mar 31;151:339-346. Epub 2018 Jan 31.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.01.030DOI Listing
March 2018

Investigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome.

Parasit Vectors 2018 03 12;11(1):168. Epub 2018 Mar 12.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.1186/s13071-018-2739-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848565PMC
March 2018

Efficacy and safety of tribendimidine versus praziquantel against Opisthorchis viverrini in Laos: an open-label, randomised, non-inferiority, phase 2 trial.

Lancet Infect Dis 2018 02 16;18(2):155-161. Epub 2017 Nov 16.

Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/S1473-3099(17)30624-2DOI Listing
February 2018

Progress in antischistosomal N,N'-diaryl urea SAR.

Bioorg Med Chem Lett 2018 02 29;28(3):244-248. Epub 2017 Dec 29.

College of Pharmacy, University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, NE, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.12.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026081PMC
February 2018

Immunohistochemical Investigations of Treatment with Ro 13-3978, Praziquantel, Oxamniquine, and Mefloquine in Schistosoma mansoni-Infected Mice.

Antimicrob Agents Chemother 2017 12 22;61(12). Epub 2017 Nov 22.

Swiss Tropical and Public Health Institute, Basel, Switzerland, and University of Basel, Basel Switzerland

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http://dx.doi.org/10.1128/AAC.01142-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700362PMC
December 2017

An explorative analysis of process and formulation variables affecting comilling in a vibrational mill: The case of praziquantel.

Int J Pharm 2017 Nov 24;533(2):402-412. Epub 2017 May 24.

Department of Pharmacy and BioTechnology, University of Bologna, Via S. Donato 19/2, 40127 Bologna, Italy.

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http://dx.doi.org/10.1016/j.ijpharm.2017.05.053DOI Listing
November 2017

Ferrocenyl, Ruthenocenyl, and Benzyl Oxamniquine Derivatives with Cross-Species Activity against Schistosoma mansoni and Schistosoma haematobium.

ACS Infect Dis 2017 09 18;3(9):645-652. Epub 2017 Jul 18.

Chimie ParisTech, PSL Research University, Laboratory for Inorganic Chemical Biology , F-75005 Paris, France.

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http://dx.doi.org/10.1021/acsinfecdis.7b00054DOI Listing
September 2017

Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model.

PLoS Negl Trop Dis 2017 Sep 21;11(9):e0005942. Epub 2017 Sep 21.

Merck Global Health Institute, Ares Trading S.A., a subsidiary of Merck KGaA (Darmstadt, Germany), Coinsins, Switzerland.

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http://dx.doi.org/10.1371/journal.pntd.0005942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626502PMC
September 2017

Efficacy of recommended drugs against soil transmitted helminths: systematic review and network meta-analysis.

BMJ 2017 Sep 25;358:j4307. Epub 2017 Sep 25.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, PO Box, CH-4002 Basel, Switzerland

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611648PMC
http://dx.doi.org/10.1136/bmj.j4307DOI Listing
September 2017

Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes.

Int J Parasitol Drugs Drug Resist 2017 08 24;7(2):159-173. Epub 2017 Mar 24.

Department of Medical Parasitology and Infection Biology Swiss Tropical and Public Health Institute, P.O. Box, CH-4002 Basel, Switzerland; University of Basel, P.O. Box, CH-4003 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ijpddr.2017.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377441PMC
August 2017

In vitro and in vivo activity of R- and S- praziquantel enantiomers and the main human metabolite trans-4-hydroxy-praziquantel against Schistosoma haematobium.

Parasit Vectors 2017 Aug 1;10(1):365. Epub 2017 Aug 1.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.1186/s13071-017-2293-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540299PMC
August 2017

Excretory/secretory products from the gastrointestinal nematode Trichuris muris.

Exp Parasitol 2017 Jul 19;178:30-36. Epub 2017 May 19.

Institute of Parasitology, McGill University, 21,111 Lakeshore Road, Sainte-Anne-de-Bellevue, Quebec H9X 3V9, Canada; Centre for Host-Parasite Interactions, Canada.

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http://dx.doi.org/10.1016/j.exppara.2017.05.003DOI Listing
July 2017

Efficacy and safety of praziquantel in preschool-aged and school-aged children infected with Schistosoma mansoni: a randomised controlled, parallel-group, dose-ranging, phase 2 trial.

Lancet Glob Health 2017 07;5(7):e688-e698

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(17)30187-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471607PMC
July 2017

Mobile-phone and handheld microscopy for neglected tropical diseases.

PLoS Negl Trop Dis 2017 07 6;11(7):e0005550. Epub 2017 Jul 6.

Department of Medicine, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1371/journal.pntd.0005550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499985PMC
July 2017

Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?

Infect Dis Poverty 2017 Mar 28;6(1):74. Epub 2017 Mar 28.

Swiss Tropical and Public Health Institute, P.O. Box, CH-4002, Basel, Switzerland.

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http://dx.doi.org/10.1186/s40249-017-0286-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371198PMC
March 2017

Unexpected low soil-transmitted helminth prevalence in the Butha-Buthe district in Lesotho, results from a cross-sectional survey.

Parasit Vectors 2017 02 8;10(1):72. Epub 2017 Feb 8.

Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.

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http://dx.doi.org/10.1186/s13071-017-1995-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299746PMC
February 2017

Revisiting the SAR of the Antischistosomal Aryl Hydantoin (Ro 13-3978).

J Med Chem 2016 12 28;59(23):10705-10718. Epub 2016 Nov 28.

College of Pharmacy, University of Nebraska Medical Center , 986125 Nebraska Medical Center, Omaha, Nebraska 68198, United States.

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http://dx.doi.org/10.1021/acs.jmedchem.6b01410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150661PMC
December 2016

Re-infection with Fasciola gigantica 6-month post-treatment with triclabendazole in cattle from mobile pastoralist husbandry systems at Lake Chad.

Vet Parasitol 2016 Oct 23;230:43-48. Epub 2016 Oct 23.

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.vetpar.2016.10.019DOI Listing
October 2016