Publications by authors named "Jennifer J Knox"

100Publications

Severe optic neuropathy as the presenting sign of leptomeningeal carcinomatosis from pancreatic cancer.

Can J Ophthalmol 2020 Dec 7;55(6):e207-e209. Epub 2020 Jun 7.

University of Toronto, Toronto, Ont.. Electronic address:

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December 2020

A phase 2 trial of sunitinib in patients with progressive paraganglioma or pheochromocytoma: the SNIPP trial.

Br J Cancer 2019 06 20;120(12):1113-1119. Epub 2019 May 20.

Department of Medical Oncology and Haematology Princess Margaret Cancer Centre, University Health Network, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada.

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June 2019

Adjuvant Therapy for Biliary Tract Cancers.

J Oncol Pract 2018 12;14(12):701-708

South East Cancer Center, University Hospital Waterford, Waterford, Ireland; and Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.

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December 2018

Sorafenib as first-line therapy in patients with advanced Child-Pugh B hepatocellular carcinoma-a meta-analysis.

Eur J Cancer 2018 12 29;105:1-9. Epub 2018 Oct 29.

Department of Medical Oncology, Princess Margaret Cancer Centre/University of Toronto, 610 University Avenue, Toronto, Ontario, M5G 2M9, Canada.

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December 2018

Baseline Albumin-Bilirubin (ALBI) Score in Western Patients With Hepatocellular Carcinoma Treated With Stereotactic Body Radiation Therapy (SBRT).

Int J Radiat Oncol Biol Phys 2018 07 12;101(4):900-909. Epub 2018 Apr 12.

Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. Electronic address:

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July 2018

Locally advanced pancreatic cancer: An emerging entity.

Curr Probl Cancer 2018 Jan - Feb;42(1):12-25. Epub 2017 Nov 16.

Princess Margaret Cancer Centre, Toronto, Canada.

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April 2019

Molecular Profiling of Patients With Advanced Colorectal Cancer: Princess Margaret Cancer Centre Experience.

Clin Colorectal Cancer 2018 03 23;17(1):73-79. Epub 2017 Oct 23.

Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address:

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March 2018

Phase I trial of radiation therapy and sorafenib in unresectable liver metastases.

Radiother Oncol 2017 05 13;123(2):234-239. Epub 2017 Feb 13.

Department of Radiation Oncology, Princess Margaret Cancer Centre, University of Toronto, Canada. Electronic address:

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May 2017

Validation of microRNA pathway polymorphisms in esophageal adenocarcinoma survival.

Cancer Med 2017 02 11;6(2):361-373. Epub 2017 Jan 11.

Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario, Canada.

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February 2017

Adjuvant therapy for resected biliary tract cancer: a review.

Chin Clin Oncol 2016 Oct 5;5(5):64. Epub 2016 Sep 5.

Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Canada.

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October 2016

Pretreatment quality-of-life score is a better discriminator of oesophageal cancer survival than performance status.

Eur J Cardiothorac Surg 2017 Jan 8;51(1):148-154. Epub 2016 Aug 8.

Division of Thoracic Surgery, University of Toronto, Toronto, ON, Canada

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January 2017

FOLFIRINOX for advanced pancreatic cancer: the Princess Margaret Cancer Centre experience.

Br J Cancer 2016 09 28;115(6):649-54. Epub 2016 Jul 28.

Department of Medical Oncology and Haematology, Princess Margaret Cancer Centre, University Health Network, Toronto M5G 2M9, Canada.

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September 2016

Baseline measure of health-related quality of life (Functional Assessment of Cancer Therapy-Esophagus) is associated with overall survival in patients with esophageal cancer.

J Thorac Cardiovasc Surg 2016 Jun 24;151(6):1571-80. Epub 2016 Feb 24.

Division of Thoracic Surgery, University of Toronto, Toronto, Ontario, Canada; Divison of Thoracic Surgery, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada. Electronic address:

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June 2016

Changes in Liver Volume Observed Following Sorafenib and Liver Radiation Therapy.

Int J Radiat Oncol Biol Phys 2016 Mar 17;94(4):729-37. Epub 2015 Dec 17.

Department of Radiation Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada. Electronic address:

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March 2016

Predictive and prognostic values of ERCC1 and XRCC1 in biliary tract cancers.

J Clin Pathol 2016 Aug 13;69(8):695-701. Epub 2016 Jan 13.

Department of Pathology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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August 2016

Can Stereotactic Body Radiotherapy Effectively Treat Hepatocellular Carcinoma?

J Clin Oncol 2016 Feb 23;34(5):404-8. Epub 2015 Dec 23.

University of Toronto, Toronto, Canada

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February 2016

Discovery and validation of vascular endothelial growth factor (VEGF) pathway polymorphisms in esophageal adenocarcinoma outcome.

Carcinogenesis 2015 Sep 25;36(9):956-62. Epub 2015 May 25.

Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and University of Toronto, 610 University Ave, Toronto, Ontario M5G 2M9, Canada.

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September 2015

Localized and systemic approaches to treating hepatocellular carcinoma.

J Clin Oncol 2015 Jun 27;33(16):1835-44. Epub 2015 Apr 27.

All authors: University of Toronto, Princess Margaret Cancer Centre, Toronto, ON, Canada.

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June 2015

Neutrophil-Lymphocyte Ratio and Pathological Response to Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer.

Clin Genitourin Cancer 2015 Aug 7;13(4):e229-e233. Epub 2015 Feb 7.

Department of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Electronic address:

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August 2015

A phase II trial of second-line axitinib following prior antiangiogenic therapy in advanced hepatocellular carcinoma.

Cancer 2015 May 6;121(10):1620-7. Epub 2015 Jan 6.

Department of Medical Oncology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; The Christie NHS Foundation Trust/University of Manchester, Withington, Manchester, United Kingdom.

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May 2015

Addressing the interplay of liver disease and hepatocellular carcinoma on patient survival: the ALBI scoring model.

Authors:
Jennifer J Knox

J Clin Oncol 2015 Feb 15;33(6):529-31. Epub 2014 Dec 15.

University of Toronto, Princess Margaret Cancer Centre, Toronto, Ontario, Canada

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February 2015

A phase II trial of bevacizumab plus temsirolimus in patients with advanced hepatocellular carcinoma.

Invest New Drugs 2015 Feb 16;33(1):241-6. Epub 2014 Oct 16.

Staff Medical Oncologist, Gastrointestinal Oncology Lead, Princess Margaret Cancer Centre, University of Toronto, 5-210, 610 University Ave, Toronto, ON, M5G 2 M9, USA,

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February 2015

Efficacy and toxicity of abiraterone and docetaxel in octogenarians with metastatic castration-resistant prostate cancer.

J Geriatr Oncol 2015 Jan 7;6(1):23-8. Epub 2014 Oct 7.

Department of Medical Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada. Electronic address:

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January 2015

Retreatment of men with metastatic castrate-resistant prostate cancer with abiraterone.

Prostate 2014 Oct 11;74(14):1462-4. Epub 2014 Aug 11.

Department of Medical Oncology and Hematology, Princess Margaret Cancer Center, University Health Network, Toronto, Canada.

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October 2014

Phase II randomized trial comparing sequential first-line everolimus and second-line sunitinib versus first-line sunitinib and second-line everolimus in patients with metastatic renal cell carcinoma.

J Clin Oncol 2014 Sep 21;32(25):2765-72. Epub 2014 Jul 21.

Robert J. Motzer, Memorial Sloan-Kettering Cancer Center, New York, NY; Carlos H. Barrios, PUCRS School of Medicine, Porto Alegre, Brazil; Tae Min Kim, Seoul National University Hospital; and Sun Young Rha, Severance Hospital, Yonsei Cancer Center, Seoul, Korea; Silvia Falcon, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru; Thomas Cosgriff, Hematology and Oncology Specialists, Metairie, LA; Graydon Harker, Utah Cancer Specialists, Salt Lake City, UT; Vichien Srimuninnimit, Siriraj Hospital, Mahidol, Thailand; Ken Pittman, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia; Roberto Sabbatini, Azienda Ospedaliero Universitaria Policlinico di Modena, Italy; Thomas W. Flaig, University of Colorado Cancer Center, Aurora, CO; Ray Page, Center for Cancer and Blood Disorders, Fort Worth, TX; Sevil E. Bavbek, American Hospital, Istanbul, Turkey; J. Thaddeus Beck, Highlands Oncology Group, Fayetteville, AR; Poulam Patel, University of Nottingham, United Kingdom; Foon-yiu Cheung, Queen Elizabeth Hospital, Kowloon, Hong Kong; Sunil Yadav, Saskatoon Cancer Centre, Saskatoon, Saskatchewan; and Jennifer J. Knox, Princess Margaret Cancer Center, University of Toronto, Toronto, Ontario, Canada; Edward M. Schiff, Dalila Sellami, and Xufang Wang, Novartis Oncology, East Hanover, NJ; Julie Niolat, Novartis Pharma SAS, Rueil-Malmaison, France; and Oezlem Anak, Novartis Pharma AG, Basel, Switzerland.

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September 2014

Systemic therapy for non-clear cell renal cell carcinomas: a systematic review and meta-analysis.

Eur Urol 2015 Apr 2;67(4):740-9. Epub 2014 Jun 2.

Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Department of Medicine, University of Toronto, Toronto, Canada. Electronic address:

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April 2015

Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis.

J Natl Cancer Inst 2014 Jun 29;106(6):dju124. Epub 2014 May 29.

Affiliations of authors: Divisions of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Department of Medicine, University of Toronto, Toronto, Canada (AJT, MGM, FEV-B, PA, RL-A, JJK, IFT, EA); Department of Medical Oncology, Institute of Oncology Ljubljana, Slovenia (BS); Medical Oncology University Hospital, Albacete, Spain (AO); University of Alabama, Birmingham Comprehensive Cancer Center, Birmingham, AL (GS); Department of Medical Oncology, Royal Melbourne Hospital, Melbourne, Australia (BT).

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June 2014

Outcome of adjuvant therapy in biliary tract cancers.

Am J Clin Oncol 2015 Aug;38(4):382-7

Departments of *Medical Oncology ∥Palliative Care Medicine #Radiation Oncology, Princess Margaret Hospital Departments of §Surgery ¶Pathology, Toronto General Hospital, Toronto, ON, Canada †Department of Gastroenterology, Edouard Herriot Hospital, Lyon, France ‡Department of Medical Oncology, Waterford Regional Hospital, Waterford, Ireland.

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August 2015

Systemic therapy for hepatocellular carcinoma.

Hepat Oncol 2014 Jan 20;1(1):23-38. Epub 2013 Dec 20.

Department of Medical Oncology, Princess Margaret Cancer Centre, 610 University Avenue, Toronto, Ontario, M5G 2M9, Canada.

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January 2014

State-of-the-art in the management of locally advanced and metastatic gallbladder cancer.

Curr Opin Oncol 2013 Jul;25(4):425-31

Department of Medical Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada.

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July 2013

Adjuvant therapy for intrahepatic cholangiocarcinoma: the debate continues.

Oncologist 2012 7;17(12):1504-7. Epub 2012 Dec 7.

Massachusetts General Hospital, 55 Fruit Street, Cancer Center POB Room 232, Boston, Massachusetts 02114, USA.

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June 2013

Endoscopic or percutaneous biliary drainage for Klatskin tumors?

J Vasc Interv Radiol 2013 Jan 22;24(1):113-21. Epub 2012 Nov 22.

Division of Medical Oncology, University of Toronto, Princess Margaret Hospital, Toronto, Ontario, Canada.

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January 2013

Adjuvant therapy in the treatment of biliary tract cancer: a systematic review and meta-analysis.

J Clin Oncol 2012 Jun 23;30(16):1934-40. Epub 2012 Apr 23.

Princess Margaret Hospital, Toronto, Ontario, Canada.

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June 2012