Publications by authors named "Jennifer J D Morrissette"

69Publications

Mutational Analysis Reinforces the Diagnosis of Nodal Marginal Zone Lymphoma With Robust PD1-positive T-Cell Hyperplasia.

Am J Surg Pathol 2020 Jun 5. Epub 2020 Jun 5.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania Philadelphia, PA.

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http://dx.doi.org/10.1097/PAS.0000000000001515DOI Listing
June 2020

Negative prognostic impact of epidermal growth factor receptor copy number gain in young adults with isocitrate dehydrogenase wild-type glioblastoma.

J Neurooncol 2019 Nov 21;145(2):321-328. Epub 2019 Sep 21.

Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania, 10th Floor, South Pavilion, 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA.

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http://link.springer.com/10.1007/s11060-019-03298-6
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http://dx.doi.org/10.1007/s11060-019-03298-6DOI Listing
November 2019

Validation of a Next-Generation Sequencing Assay Targeting RNA for the Multiplexed Detection of Fusion Transcripts and Oncogenic Isoforms.

Arch Pathol Lab Med 2020 01 18;144(1):90-98. Epub 2019 Jun 18.

From the Center for Personalized Diagnostics, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia.

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http://www.archivesofpathology.org/doi/10.5858/arpa.2018-044
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http://dx.doi.org/10.5858/arpa.2018-0441-OADOI Listing
January 2020

Longitudinal targeted next-generation sequencing in a patient with acute myeloid leukaemia.

Br J Haematol 2019 09 17;186(6):801. Epub 2019 Jun 17.

Division of Precision and Computational Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.16048DOI Listing
September 2019

mutations in acute myeloid leukemia.

Leuk Lymphoma 2019 06 11;60(6):1601-1602. Epub 2019 Jan 11.

a Department of Pathology and Laboratory Medicine , Hospital of University of Pennsylvania , Philadelphia , PA , USA.

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http://dx.doi.org/10.1080/10428194.2018.1537488DOI Listing
June 2019

Validation of a next-generation sequencing oncology panel optimized for low input DNA.

Cancer Genet 2018 12 19;228-229:55-63. Epub 2018 Sep 19.

Hospital of the University of Pennsylvania, Division of Precision and Computational Diagnostics, Department of Pathology & Laboratory Medicine, 3020 Market Street, Suite 220, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2018.08.004DOI Listing
December 2018

Classes of ITD Predict Outcomes in AML Patients Treated with FLT3 Inhibitors.

Clin Cancer Res 2019 01 4;25(2):573-583. Epub 2018 Sep 4.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-18-0655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335170PMC
January 2019

Interim PET/CT Result Is Not Predictive of Survival in Patients With MYC-rearranged Non-Burkitt Aggressive B-cell Lymphoma.

Clin Lymphoma Myeloma Leuk 2018 10 15;18(10):673-678. Epub 2018 Jun 15.

Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.clml.2018.06.012DOI Listing
October 2018

Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development.

Cancer Cell 2018 07;34(1):163-177.e7

Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424337PMC
July 2018

A wild type mutational status confers a survival advantage in pancreatic ductal adenocarcinoma.

J Gastrointest Oncol 2018 Feb;9(1):1-10

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.21037/jgo.2017.10.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848049PMC
February 2018

ROS1 Rearrangement in a Case of Classic Biphasic Pulmonary Blastoma.

Int J Surg Pathol 2018 Jun 2;26(4):360-363. Epub 2018 Jan 2.

1 Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1177/1066896917749928DOI Listing
June 2018

Marginal zone lymphoma-derived interfollicular diffuse large B-cell lymphoma harboring 20q12 chromosomal deletion and missense mutation of BIRC3 gene: a case report.

Diagn Pathol 2016 Dec 19;11(1):137. Epub 2016 Dec 19.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 7 E Gates Pavilion, 3400 Spruce Street, Philadelphia, 19104-4283, PA, USA.

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http://dx.doi.org/10.1186/s13000-016-0588-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168845PMC
December 2016

BRAF kinase domain mutations in de novo acute myeloid leukemia with monocytic differentiation.

Leuk Lymphoma 2017 03 22;58(3):743-745. Epub 2016 Aug 22.

a Department of Pathology and Laboratory Medicine , Hospital of University of Pennsylvania , PA , USA.

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http://dx.doi.org/10.1080/10428194.2016.1213830DOI Listing
March 2017

Clinical Utility of Next-Generation Sequencing for Oncogenic Mutations in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2016 11 28;22(11):1961-1967. Epub 2016 Jul 28.

Blood and Marrow Transplantation Program and Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, New York. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067228PMC
http://dx.doi.org/10.1016/j.bbmt.2016.07.018DOI Listing
November 2016

A novel approach for next-generation sequencing of circulating tumor cells.

Mol Genet Genomic Med 2016 Jul 28;4(4):395-406. Epub 2016 Feb 28.

Department of MedicineUniversity of Pennsylvania Perelman School of MedicinePhiladelphiaPennsylvania; Abramson Cancer CenterUniversity of Pennsylvania Perelman School of MedicinePhiladelphiaPennsylvania.

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http://dx.doi.org/10.1002/mgg3.210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947859PMC
July 2016

Detection of Molecular Alterations in Medullary Thyroid Carcinoma Using Next-Generation Sequencing: an Institutional Experience.

Endocr Pathol 2016 Dec;27(4):359-362

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s12022-016-9446-3DOI Listing
December 2016

A Modified Integrated Genetic Model for Risk Prediction in Younger Patients with Acute Myeloid Leukemia.

PLoS One 2016 6;11(4):e0153016. Epub 2016 Apr 6.

Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153016PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822876PMC
August 2016

Building a Robust Tumor Profiling Program: Synergy between Next-Generation Sequencing and Targeted Single-Gene Testing.

PLoS One 2016 4;11(4):e0152851. Epub 2016 Apr 4.

Center for Personalized Diagnostics, Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152851PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820127PMC
August 2016

Using "residual" FNA rinse and body fluid specimens for next-generation sequencing: An institutional experience.

Cancer Cytopathol 2016 May 18;124(5):324-9. Epub 2015 Dec 18.

Department of Pathology and Laboratory Medicine, Center for Personalized Diagnostics, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/cncy.21666DOI Listing
May 2016

STK11 Mutation Identified in Thyroid Carcinoma.

Endocr Pathol 2016 Mar;27(1):65-9

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA.

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http://link.springer.com/content/pdf/10.1007%2Fs12022-015-94
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http://link.springer.com/10.1007/s12022-015-9411-6
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http://dx.doi.org/10.1007/s12022-015-9411-6DOI Listing
March 2016

Transmission of an expanding donor-derived del(20q) clone through allogeneic hematopoietic stem cell transplantation without the development of a hematologic neoplasm.

Cancer Genet 2015 Dec 3;208(12):625-9. Epub 2015 Nov 3.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.cancergen.2015.10.003DOI Listing
December 2015

PTEN and TP53 Mutations in Oncocytic Follicular Carcinoma.

Endocr Pathol 2015 Dec;26(4):365-9

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s12022-015-9403-6DOI Listing
December 2015

NPM1 mutation is associated with leukemia cutis in acute myeloid leukemia with monocytic features.

Haematologica 2015 Oct 25;100(10):e412-4. Epub 2015 Jun 25.

Division of Hematology & Oncology, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

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http://dx.doi.org/10.3324/haematol.2015.129346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591778PMC
October 2015

Development and implementation of a custom integrated database with dashboards to assist with hematopathology specimen triage and traffic.

J Pathol Inform 2014 28;5(1):29. Epub 2014 Aug 28.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania and Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.4103/2153-3539.139709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168549PMC
September 2014

What you are missing could matter: a rare, complex BRAF mutation affecting codons 599, 600, and 601 uncovered by next generation sequencing.

Cancer Genet 2014 Jun 18;207(6):272-5. Epub 2014 Jun 18.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2014.06.022DOI Listing
June 2014

'Double-Hit' cytogenetic status may not be predicted by baseline clinicopathological characteristics and is highly associated with overall survival in B cell lymphoma patients.

Br J Haematol 2014 Aug 25;166(3):369-74. Epub 2014 Apr 25.

Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.12901DOI Listing
August 2014

Understanding the limitations of next generation sequencing informatics, an approach to clinical pipeline validation using artificial data sets.

Cancer Genet 2013 Dec 28;206(12):441-8. Epub 2013 Nov 28.

Center for Personalized Diagnostics, University of Pennsylvania School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.cancergen.2013.11.005DOI Listing
December 2013

Reply: To PMID 23529082.

Am J Obstet Gynecol 2014 Jul 10;211(1):81. Epub 2014 Jan 10.

Stanford University School of Medicine, Palo Alto, CA.

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http://dx.doi.org/10.1016/j.ajog.2014.01.015DOI Listing
July 2014

BRAF V600E is also seen in unclassifiable splenic B-cell lymphoma/leukemia, a potential mimic of hairy cell leukemia.

Blood 2013 Oct;122(17):3084-5

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1182/blood-2013-07-513523DOI Listing
October 2013

Is it time to sound an alarm about false-positive cell-free DNA testing for fetal aneuploidy?

Am J Obstet Gynecol 2013 Nov 22;209(5):415-9. Epub 2013 Mar 22.

Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA; Prenatal Cytogenetic Laboratory, Perelman School of Medicine, University of Pennsylvania, Philadelphia PA.

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http://dx.doi.org/10.1016/j.ajog.2013.03.027DOI Listing
November 2013

Acute myeloid leukemia: conventional cytogenetics, FISH, and moleculocentric methodologies.

Clin Lab Med 2011 Dec;31(4):659-86, x

Department of Pathology and Laboratory Medicine, University of Pennsylvania, 201 John Morgan Building, 3620 Hamilton Walk, Philadelphia, PA 19104-4283, USA.

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http://dx.doi.org/10.1016/j.cll.2011.08.006DOI Listing
December 2011

Hyperdiploidy with trisomy 9 and deletion of the CDKN2A locus in T-cell acute lymphoblastic leukemia.

Cancer Genet Cytogenet 2009 Apr;190(2):121-4

Department of Pathology and Laboratory Medicine, Section of Cytogenetics, Drexel University College of Medicine, St. Christopher's Hospital for Children, 3601 A Street, Philadelphia, PA 19134, USA.

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http://dx.doi.org/10.1016/j.cancergencyto.2008.12.012DOI Listing
April 2009

Improvement of pancytopenia and thrombocytopenia with decreasing mosaicism for isochromosome Xp.

Pediatr Blood Cancer 2009 May;52(5):650-2

Department of Pathology and Laboratory Medicine, St. Christopher's Hospital for Children and Drexel University College of Medicine, Philadelphia, Pennsylvania 19134, USA.

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http://dx.doi.org/10.1002/pbc.21890DOI Listing
May 2009

Down syndrome with low hypodiploidy in precursor B-cell acute lymphoblastic leukemia.

Cancer Genet Cytogenet 2006 Aug;169(1):58-61

Department of Pathology and Laboratory Medicine, Section of Cytogenetics, Drexel University College of Medicine, St. Christopher's Hospital for Children, Philadelphia, PA 19134, USA.

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http://dx.doi.org/10.1016/j.cancergencyto.2006.02.007DOI Listing
August 2006

A patient with mosaic partial trisomy 18 resulting from dicentric chromosome breakage.

Am J Med Genet A 2005 Aug;137(2):208-12

Division of Human Genetics and Molecular Biology, 1007A Abramson Research Center, Children's Hospital of Philadelphia, 34th Street & Civic Center Boulevard, Philadelphia, PA 19104, USA.

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http://doi.wiley.com/10.1002/ajmg.a.30845
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http://dx.doi.org/10.1002/ajmg.a.30845DOI Listing
August 2005

Patient with trisomy 9p and a hypoplastic left heart with a tricentric chromosome 9.

Am J Med Genet A 2003 Dec;123A(3):279-84

Division of Human Genetics and Molecular Biology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

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http://doi.wiley.com/10.1002/ajmg.a.20293
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http://dx.doi.org/10.1002/ajmg.a.20293DOI Listing
December 2003

Conditional JAG1 mutation shows the developing heart is more sensitive than developing liver to JAG1 dosage.

Am J Hum Genet 2003 Apr 14;72(4):1065-70. Epub 2003 Mar 14.

Division of Human Genetics and Molecular Biology, Department of Pediatrics and Clinical Laboratories, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180339PMC
http://dx.doi.org/10.1086/374386DOI Listing
April 2003