Jennifer E Van Eyk

Jennifer E Van Eyk

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Jennifer E Van Eyk

Publications by authors named "Jennifer E Van Eyk"

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Mining the Proteome Associated with Rheumatic and Autoimmune Diseases.

J Proteome Res 2019 Oct 23. Epub 2019 Oct 23.

Grupo de Investigación de Reumatología, INIBIC-Complejo Hospitalario Universitario de A Coruña, SERGAS , Departamento de Medicina Universidad de A Coruña , A Coruña 15006 , Spain.

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http://dx.doi.org/10.1021/acs.jproteome.9b00360DOI Listing
October 2019

Multipotent fetal-derived Cdx2 cells from placenta regenerate the heart.

Proc Natl Acad Sci U S A 2019 Jun 20;116(24):11786-11795. Epub 2019 May 20.

Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029;

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http://dx.doi.org/10.1073/pnas.1811827116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576083PMC
June 2019

Mapping Citrullinated Sites in Multiple Organs of Mice Using Hypercitrullinated Library.

J Proteome Res 2019 May 23;18(5):2270-2278. Epub 2019 Apr 23.

The Smidt Heart Institute, Department of Medicine , Cedars-Sinai Medical Center , Los Angeles , California 90048 , United States.

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http://dx.doi.org/10.1021/acs.jproteome.9b00118DOI Listing
May 2019

In Vitro and In Vivo Proteomic Comparison of Human Neural Progenitor Cell-Induced Photoreceptor Survival.

Proteomics 2019 02 2;19(3):e1800213. Epub 2019 Jan 2.

Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA90048, California.

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http://dx.doi.org/10.1002/pmic.201800213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422354PMC
February 2019

A Proteomics Workflow for Dual Labeling Biotin Switch Assay to Detect and Quantify Protein S-Nitroylation.

Methods Mol Biol 2018 ;1747:89-101

Medicine and Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-7695-9_8DOI Listing
January 2019

Precision Medicine: Role of Proteomics in Changing Clinical Management and Care.

J Proteome Res 2019 01 22;18(1):1-6. Epub 2018 Oct 22.

Department of Genetics , Stanford University School of Medicine , Stanford , California 94305 , United States.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00504
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http://dx.doi.org/10.1021/acs.jproteome.8b00504DOI Listing
January 2019

Contractility kits promote assembly of the mechanoresponsive cytoskeletal network.

J Cell Sci 2019 01 16;132(2). Epub 2019 Jan 16.

Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

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http://dx.doi.org/10.1242/jcs.226704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362397PMC
January 2019

Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity.

J Proteome Res 2018 12 9;17(12):4267-4278. Epub 2018 Oct 9.

Department of Medicine, Division of Cardiology, Consortium for Fibrosis Research and Translation, Anschutz Medical Campus , University of Colorado Denver , Aurora , Colorado 80045 , United States.

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http://dx.doi.org/10.1021/acs.jproteome.8b00393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606054PMC
December 2018

Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice.

Am J Physiol Heart Circ Physiol 2018 11 13;315(5):H1112-H1126. Epub 2018 Jul 13.

Advanced Clinical Biosystems Research Institute, The Smidt Heart Institute, Cedars-Sinai Medical Center , Los Angeles, California.

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http://dx.doi.org/10.1152/ajpheart.00089.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335018PMC
November 2018

Precision Medicine.

Circulation 2018 11;138(20):2172-2174

Department of Pathology (K.S.), Cedars-Sinai Medical Center, Los Angeles, CA.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036781DOI Listing
November 2018

Evaluating utility and compliance in a patient-based eHealth study using continuous-time heart rate and activity trackers.

J Am Med Inform Assoc 2018 10;25(10):1386-1391

Medical Imaging and Informatics Group, Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1093/jamia/ocy067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188512PMC
October 2018

Phospho-Proteomic Analysis of Cardiac Dyssynchrony and Resynchronization Therapy.

Proteomics 2018 10 30;18(19):e1800079. Epub 2018 Aug 30.

Department of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.

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http://dx.doi.org/10.1002/pmic.201800079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417799PMC
October 2018

Sex differences in ischemic heart disease and heart failure biomarkers.

Biol Sex Differ 2018 09 17;9(1):43. Epub 2018 Sep 17.

Barbra Streisand Women's Heart Center, Cedars-Sinai Smidt Heart Institute, 127 S. San Vicente Blvd, Suite A3206, Los Angeles, CA, 90048, USA.

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http://dx.doi.org/10.1186/s13293-018-0201-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142320PMC
September 2018

Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome: Where There Is a Will, There Is a Way.

Circ Res 2018 04;122(9):1221-1237

From the Advanced Clinical BioSystems Research Institute, Smidt Heart Institute, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.310966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963703PMC
April 2018

Molecular Profile of Priapism Associated with Low Nitric Oxide Bioavailability.

J Proteome Res 2018 03 12;17(3):1031-1040. Epub 2018 Feb 12.

Advanced Clinical Biosystems Research Institute, Department of Medicine and The Heart Institute, Cedars-Sinai Medical Center , Los Angeles, California 90048, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419954PMC
March 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Mapping Biological Networks from Quantitative Data-Independent Acquisition Mass Spectrometry: Data to Knowledge Pipelines.

Methods Mol Biol 2017 ;1558:395-413

Advanced Clinical BioSystems Research Institute, Cedars Sinai Medical Center, Heart Institute, Los Angeles, CA, 90048, USA.

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http://dx.doi.org/10.1007/978-1-4939-6783-4_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844627PMC
February 2018

Highly Reproducible Automated Proteomics Sample Preparation Workflow for Quantitative Mass Spectrometry.

J Proteome Res 2018 01 10;17(1):420-428. Epub 2017 Nov 10.

Advanced Clinical Biosystems Institute, Heart Institute, Cedars Sinai Medical Center , Los Angeles, California 90048, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845026PMC
January 2018

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.

Authors:
Alexandra B Keenan Sherry L Jenkins Kathleen M Jagodnik Simon Koplev Edward He Denis Torre Zichen Wang Anders B Dohlman Moshe C Silverstein Alexander Lachmann Maxim V Kuleshov Avi Ma'ayan Vasileios Stathias Raymond Terryn Daniel Cooper Michele Forlin Amar Koleti Dusica Vidovic Caty Chung Stephan C Schürer Jouzas Vasiliauskas Marcin Pilarczyk Behrouz Shamsaei Mehdi Fazel Yan Ren Wen Niu Nicholas A Clark Shana White Naim Mahi Lixia Zhang Michal Kouril John F Reichard Siva Sivaganesan Mario Medvedovic Jaroslaw Meller Rick J Koch Marc R Birtwistle Ravi Iyengar Eric A Sobie Evren U Azeloglu Julia Kaye Jeannette Osterloh Kelly Haston Jaslin Kalra Steve Finkbiener Jonathan Li Pamela Milani Miriam Adam Renan Escalante-Chong Karen Sachs Alex Lenail Divya Ramamoorthy Ernest Fraenkel Gavin Daigle Uzma Hussain Alyssa Coye Jeffrey Rothstein Dhruv Sareen Loren Ornelas Maria Banuelos Berhan Mandefro Ritchie Ho Clive N Svendsen Ryan G Lim Jennifer Stocksdale Malcolm S Casale Terri G Thompson Jie Wu Leslie M Thompson Victoria Dardov Vidya Venkatraman Andrea Matlock Jennifer E Van Eyk Jacob D Jaffe Malvina Papanastasiou Aravind Subramanian Todd R Golub Sean D Erickson Mohammad Fallahi-Sichani Marc Hafner Nathanael S Gray Jia-Ren Lin Caitlin E Mills Jeremy L Muhlich Mario Niepel Caroline E Shamu Elizabeth H Williams David Wrobel Peter K Sorger Laura M Heiser Joe W Gray James E Korkola Gordon B Mills Mark LaBarge Heidi S Feiler Mark A Dane Elmar Bucher Michel Nederlof Damir Sudar Sean Gross David F Kilburn Rebecca Smith Kaylyn Devlin Ron Margolis Leslie Derr Albert Lee Ajay Pillai

Cell Syst 2018 01 29;6(1):13-24. Epub 2017 Nov 29.

NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.cels.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799026PMC
January 2018

Profiling B-Type Natriuretic Peptide Cleavage Peptidoforms in Human Plasma by Capillary Electrophoresis with Electrospray Ionization Mass Spectrometry.

J Proteome Res 2017 12 2;16(12):4515-4522. Epub 2017 Oct 2.

Heart Institute, Cedars-Sinai Medical Center , 127 South San Vicente Boulevard, Los Angeles, California 90048, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00482DOI Listing
December 2017

Transient receptor potential channel 6 regulates abnormal cardiac S-nitrosylation in Duchenne muscular dystrophy.

Proc Natl Acad Sci U S A 2017 12 29;114(50):E10763-E10771. Epub 2017 Nov 29.

Advanced Clinical BioSystems Research Institute, Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048;

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http://dx.doi.org/10.1073/pnas.1712623114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740634PMC
December 2017

Extracellular matrix downregulation in the Drosophila heart preserves contractile function and improves lifespan.

Matrix Biol 2017 10 25;62:15-27. Epub 2016 Oct 25.

Biomedical Sciences Program, UC, San Diego; La Jolla, CA 92093, USA; Department of Bioengineering, UC, San Diego; La Jolla, CA 92093, USA; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2016.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405015PMC
October 2017

Advances in quantifying apolipoproteins using LC-MS/MS technology: implications for the clinic.

Expert Rev Proteomics 2017 10 8;14(10):869-880. Epub 2017 Sep 8.

a Cedars-Sinai Medical Center, The Advanced Clinical Biosystems Research Institute , The Heart Institute , Los Angeles , CA , USA.

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http://dx.doi.org/10.1080/14789450.2017.1374859DOI Listing
October 2017

Exploring ribosome composition and newly synthesized proteins through proteomics and potential biomedical applications.

Expert Rev Proteomics 2017 06 26;14(6):529-543. Epub 2017 May 26.

a Heart Institute , Cedars-Sinai Medical Center , Los Angeles , CA , USA.

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http://dx.doi.org/10.1080/14789450.2017.1333424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242274PMC
June 2017

A Roadmap to Successful Clinical Proteomics.

Clin Chem 2017 01 18;63(1):245-247. Epub 2016 Nov 18.

Advanced Clinical Biosystems Research Institute, Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA;

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http://dx.doi.org/10.1373/clinchem.2016.254664DOI Listing
January 2017

Multiple and Selective Reaction Monitoring Using Triple Quadrupole Mass Spectrometer: Preclinical Large Cohort Analysis.

Methods Mol Biol 2016 ;1410:249-64

Advanced Clinical Biosystems Research Institute, The Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-3524-6_15DOI Listing
December 2016

Methods for SWATH™: Data Independent Acquisition on TripleTOF Mass Spectrometers.

Methods Mol Biol 2016 ;1410:265-79

Advanced Clinical Biosystems Research Institute, The Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-3524-6_16DOI Listing
December 2016

Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems.

J Proteome Res 2016 11 19;15(11):4126-4134. Epub 2016 Jul 19.

Advanced Clinical Biosystems Research Institute, Department of Medicine and The Heart Institute, Cedars-Sinai Medical Center , Los Angeles, California 90048, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120959PMC
November 2016

Highlights of the Biology and Disease-driven Human Proteome Project, 2015-2016.

J Proteome Res 2016 11 20;15(11):3979-3987. Epub 2016 Sep 20.

Center for Computational Medicine and Bioinformatics, University of Michigan , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129618PMC
November 2016

The proteome of normal human retrobulbar optic nerve and sclera.

Proteomics 2016 10;16(19):2592-2596

Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/pmic.201600229DOI Listing
October 2016

Effect of peptide assay library size and composition in targeted data-independent acquisition-MS analyses.

Proteomics 2016 08;16(15-16):2221-37

Advanced Clinical BioSystems Research Institute, Heart Institute, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1002/pmic.201600007DOI Listing
August 2016

Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance.

Am J Physiol Heart Circ Physiol 2016 07 6;311(1):H219-28. Epub 2016 May 6.

Cedars-Sinai Heart Institute and Department of Medicine, Los Angeles, California; Barbra Streisand Women's Heart Center of Cedars-Sinai Medical Center, Los Angeles, California; and.

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http://dx.doi.org/10.1152/ajpheart.00041.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967197PMC
July 2016

Defining the proteome of human iris, ciliary body, retinal pigment epithelium, and choroid.

Proteomics 2016 Apr 11;16(7):1146-53. Epub 2016 Mar 11.

Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/pmic.201500188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833206PMC
April 2016

Protein kinase G signaling in cardiac pathophysiology: Impact of proteomics on clinical trials.

Proteomics 2016 Mar 16;16(5):894-905. Epub 2016 Feb 16.

Advanced Clinical Biosystems Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1002/pmic.201500401DOI Listing
March 2016

An Empirical Approach to Signature Peptide Choice for Selected Reaction Monitoring: Quantification of Uromodulin in Urine.

Clin Chem 2016 Jan 20;62(1):198-207. Epub 2015 Nov 20.

Advanced Clinical Biosystems Research Institute, The Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD;

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http://www.clinchem.org/content/early/2015/11/19/clinchem.20
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http://www.clinchem.org/cgi/doi/10.1373/clinchem.2015.242495
Publisher Site
http://dx.doi.org/10.1373/clinchem.2015.242495DOI Listing
January 2016

Identification of glycoproteins containing specific glycans using a lectin-chemical method.

Anal Chem 2015 20;87(9):4683-7. Epub 2015 Apr 20.

§Institute of Biophysics, Chinese Academy of Sciences, Beijing, China 100101.

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http://dx.doi.org/10.1021/ac504304vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496425PMC
December 2015

Priorities and trends in the study of proteins in eye research, 1924-2014.

Proteomics Clin Appl 2015 Dec 16;9(11-12):1105-22. Epub 2015 Sep 16.

Advanced Clinical BioSystems Research Institute, The Heart Institute and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1002/prca.201500006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695326PMC
December 2015

Citrullination of myofilament proteins in heart failure.

Cardiovasc Res 2015 Nov 25;108(2):232-42. Epub 2015 Jun 25.

The Heart Institute and Department of Medicine, Cedars-Sinai Medical Center, Advanced Clinical BioSystems Research Institute, Advanced Health Science Building, 9229, Los Angeles, CA, USA Bayview Proteomics Center, Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1093/cvr/cvv185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614685PMC
November 2015

Identification of a Set of Conserved Eukaryotic Internal Retention Time Standards for Data-independent Acquisition Mass Spectrometry.

Mol Cell Proteomics 2015 Oct 21;14(10):2800-13. Epub 2015 Jul 21.

§Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland; §§Faculty of Science, University of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.1074/mcp.O114.042267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597153PMC
October 2015

Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection.

Circ Res 2015 Oct 3;117(10):846-57. Epub 2015 Sep 3.

From the Department of Biological Chemistry (H.S.C., C.I.M., R.N.C., J.E.V.E.), Division of Cardiology, Department of Medicine (V.V., P.P.R., D.A.K., J.E.V.E.), The Johns Hopkins NHLBI Proteomics Innovation Center on Heart Failure (H.S.C., V.V., D.A.K., J.E.V.E.), Department of Medicine, Mass Spectrometry and Proteomic Core Facility (R.N.C.), Johns Hopkins University School of Medicine, Baltimore, MD; Thermo Fisher Scientific, Rockford, IL (R.D.B., J.C.R.); Advanced Clinical Biosystems Research Institute, Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA (V.V., E.L.C., J.E.V.E.); Department of Medicine, Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL (W.B., J.M.H.); Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada (C.I.M.); and Division of Cardiology, Medical University of Graz, Austria (P.P.R.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979977PMC
October 2015

Biomarkers of pulmonary hypertension in patients with scleroderma: a case-control study.

Arthritis Res Ther 2015 Aug 6;17:201. Epub 2015 Aug 6.

Division of Rheumatology, Department of Medicine, Johns Hopkins University, 5200 Eastern Avenue, Mason F. Lord Building, Center Tower, Suite 4000, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1186/s13075-015-0712-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527208PMC
August 2015

Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart.

Sci Transl Med 2015 Jun;7(292):292ra99

Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA. Biomedical Sciences Program, University of California, San Diego, La Jolla, CA 92093, USA. Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa5843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507505PMC
June 2015

Emerging proteomic technologies for elucidating context-dependent cellular signaling events: A big challenge of tiny proportions.

Proteomics 2015 May 10;15(9):1486-502. Epub 2015 Feb 10.

Department of Medicine, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA; Advanced Clinical Biosystems Research Institute, Los Angeles, CA, USA; Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

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http://dx.doi.org/10.1002/pmic.201400448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743877PMC
May 2015

A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis.

J Mol Cell Cardiol 2015 May 11;82:93-103. Epub 2015 Mar 11.

Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands; ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.yjmcc.2015.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405491PMC
May 2015

Universal therapeutic targeting of age-related protein quality control system dysfunction in chronic diseases?

Trends Cardiovasc Med 2015 Apr 7;25(3):248-9. Epub 2015 Feb 7.

Advanced Clinical Biosystems Research Institute, Cedar Sinai Medical Center, Los Angeles, CA; Heart Institute, Cedar Sinai Medical Center, Los Angeles, CA; Department of Medicine, Cedar Sinai Medical Center, Los Angeles, CA. Electronic address:

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http://dx.doi.org/10.1016/j.tcm.2015.01.012DOI Listing
April 2015

Posttranslational modifications of lysine and evolving role in heart pathologies-recent developments.

Proteomics 2015 Mar 19;15(5-6):1164-80. Epub 2015 Jan 19.

Institute of Analytical Chemistry of the Academy of Sciences of the Czech Republic, v. v. i, Brno, Czech Republic.

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http://dx.doi.org/10.1002/pmic.201400312DOI Listing
March 2015

Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity.

J Lipid Res 2015 Mar 21;56(3):546-61. Epub 2014 Dec 21.

Division of Endocrinology, Metabolism, and Diabetes and Program in Molecular Medicine, University of Utah School of Medicine, Salt Lake City, UT 84112 Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112 Fraternal Order of Eagles Diabetes Research Center and Division of Endocrinology and Metabolism, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242.

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http://dx.doi.org/10.1194/jlr.M055152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340303PMC
March 2015

The proteome of human retina.

Proteomics 2015 Feb 14;15(4):836-40. Epub 2015 Jan 14.

Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/pmic.201400397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329094PMC
February 2015

Glycoproteins identified from heart failure and treatment models.

Proteomics 2015 Jan 9;15(2-3):567-79. Epub 2014 Oct 9.

Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/pmic.201400151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492696PMC
January 2015

Sizing up models of heart failure: Proteomics from flies to humans.

Proteomics Clin Appl 2014 Oct 25;8(9-10):653-64. Epub 2014 Jun 25.

Department of Medicine, Division of Cardiology, The Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/prca.201300123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282793PMC
October 2014

PKCα-specific phosphorylation of the troponin complex in human myocardium: a functional and proteomics analysis.

PLoS One 2013 7;8(10):e74847. Epub 2013 Oct 7.

Laboratory for Physiology, Institute for Cardiovascular Research, VU Medical Center, Amsterdam, The Netherlands ; Johns Hopkins Bayview Proteomics Center, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074847PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792062PMC
June 2014

The role of O-GlcNAc signaling in the pathogenesis of diabetic retinopathy.

Proteomics Clin Appl 2014 Apr 19;8(3-4):218-31. Epub 2014 Feb 19.

Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/prca.201300076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037871PMC
April 2014

Pulseless electric activity: definition, causes, mechanisms, management, and research priorities for the next decade: report from a National Heart, Lung, and Blood Institute workshop.

Circulation 2013 Dec;128(23):2532-41

University of Miami Miller School of Medicine, Miami, FL (R.J.M.); Johns Hopkins Medical Institutions (H.H., J.E.V.E., M.L.W.); National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (D.A.E., R.B., D.A.L., G.S., J.D.W.); Cedars-Sinai Heart Institute, Los Angeles, CA (S.S.C., J.I.G.); University of Calgary, Calgary, AB, Canada (A.M.G.); University of Toronto, Toronto, ON, Canada (P.L.); UCLA Harbor Medical Center, Torrance, CA (J.T.N.); Virginia Commonwealth University Medical Center, Richmond (J.P.O.); University of Alabama at Birmingham, Birmingham (G.P.W.); and the Krannert Institute of Cardiology, Indianapolis, IN (D.P.Z.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.004490DOI Listing
December 2013

Using pure protein to build a multiple reaction monitoring mass spectrometry assay for targeted detection and quantitation.

Methods Mol Biol 2013 ;1005:199-213

Division of Cardiology, Department of Medicine, Johns Hopkins Bayview Proteomics Center, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/978-1-62703-386-2_16DOI Listing
October 2013

Optimized method for identification of the proteomes secreted by cardiac cells.

Methods Mol Biol 2013 ;1005:225-35

Division of Cardiology, Department of Medicine, School of Medicine, Johns Hopkins Bayview Proteomics Center, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/978-1-62703-386-2_18DOI Listing
October 2013

Identification and characterization of citrulline-modified brain proteins by combining HCD and CID fragmentation.

Proteomics 2013 Sep 7;13(17):2682-91. Epub 2013 Aug 7.

Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/pmic.201300064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864592PMC
September 2013

The Human Eye Proteome Project: perspectives on an emerging proteome.

Proteomics 2013 Aug;13(16):2500-11

Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/pmic.201300075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978387PMC
August 2013

Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts.

J Mol Cell Cardiol 2013 Jul 22;60:116-20. Epub 2013 Apr 22.

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2013.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710717PMC
July 2013