Publications by authors named "Jennifer E Towne"

24Publications

A Role for IL-12 in IBD after All?

Immunity 2019 08;51(2):209-211

Immunology Discovery, Janssen Research and Development, 3210 Merryfield Row, San Diego, CA 92121, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.07.008DOI Listing
August 2019

Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model.

Cell Mol Gastroenterol Hepatol 2019 9;8(2):193-195. Epub 2019 May 9.

Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts; Division of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jcmgh.2019.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661391PMC
July 2020

Publisher Correction: Get the IL-17F outta here!

Nat Immunol 2019 Mar;20(3):374

Janssen Immunology Research and Development, Spring House, PA, USA.

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http://dx.doi.org/10.1038/s41590-019-0332-2DOI Listing
March 2019

Get the IL-17F outta here!

Nat Immunol 2018 07;19(7):648-650

Janssen Immunology Research and Development, Spring House, PA, USA.

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http://dx.doi.org/10.1038/s41590-018-0141-zDOI Listing
July 2018

Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease.

Gastroenterology 2018 09 18;155(3):815-828. Epub 2018 May 18.

Department of Pathology and Immunology, Division of Gastroenterology, Inflammatory Bowel Disease Program, St Louis, Missouri. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.05.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378688PMC
September 2018

Regulation and function of interleukin-36 cytokines.

Immunol Rev 2018 01;281(1):169-178

Division of Rheumatology, Department of Internal Medicine Specialties & Department of Pathology-Immunology, University Hospitals of Geneva and University of Geneva, Geneva, Switzerland.

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http://dx.doi.org/10.1111/imr.12610DOI Listing
January 2018

Mutation in IL36RN impairs the processing and regulatory function of the interleukin-36-receptor antagonist and is associated with DITRA syndrome.

Exp Dermatol 2019 10 26;28(10):1114-1117. Epub 2017 Oct 26.

Sorbonne Paris Cité, IMAGINE Institute, Necker Hospital, Enfants-Malades, UMR 1163, Paris-Descartes University, Paris, France.

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http://dx.doi.org/10.1111/exd.13387DOI Listing
October 2019

Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation.

Immunity 2015 Oct 29;43(4):739-50. Epub 2015 Sep 29.

Department of Inflammation, Amgen, Inc., 1201 Amgen Court West, Seattle, WA 98117, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.08.019DOI Listing
October 2015

Regulation and function of interleukin-36 cytokines in homeostasis and pathological conditions.

J Leukoc Biol 2015 Apr 11;97(4):645-52. Epub 2015 Feb 11.

*Division of Rheumatology, Departments of Internal Medicine Specialties and Pathology-Immunology, University Hospitals of Geneva and University of Geneva, Switzerland; and Department of Inflammation Research, Amgen, Seattle, Washington, USA

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http://dx.doi.org/10.1189/jlb.3RI1014-495RDOI Listing
April 2015

Combined anti-CD40 and anti-IL-23 monoclonal antibody therapy effectively suppresses tumor growth and metastases.

Cancer Res 2014 May 20;74(9):2412-21. Epub 2014 Feb 20.

Authors' Affiliations: Cancer Immunology Program, Trescowthick Laboratories, Peter MacCallum Cancer Centre, St. Andrews Place, East Melbourne; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria; Immunology in Cancer and Infection Laboratory; Cancer Immunoregulation and Immunotherapy Laboratory, Queensland Institute of Medical Research; School of Medicine, University of Queensland, Herston, Queensland, Australia; and AMGEN Incorporated, Seattle, Washington.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1646DOI Listing
May 2014

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.

Trends Immunol 2013 Apr 3;34(4):174-81. Epub 2013 Jan 3.

Laboratory for Investigative Dermatology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.it.2012.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721313PMC
April 2013

Opposing roles for IL-23 and IL-12 in maintaining occult cancer in an equilibrium state.

Cancer Res 2012 Aug 6;72(16):3987-96. Epub 2012 Aug 6.

Cancer Immunology Program, Trescowthick Laboratories, Peter MacCallum Cancer Centre, St. Andrews Place, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384890PMC
August 2012

Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity.

J Biol Chem 2011 Dec 29;286(49):42594-602. Epub 2011 Sep 29.

Department of Inflammation Research, Amgen Incorporated, Seattle, Washington 98119, USA.

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http://dx.doi.org/10.1074/jbc.M111.267922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234937PMC
December 2011

Anti-IL-23 monoclonal antibody synergizes in combination with targeted therapies or IL-2 to suppress tumor growth and metastases.

Cancer Res 2011 Mar 31;71(6):2077-86. Epub 2011 Jan 31.

Cancer Immunology Program, Trescowthick Laboratories, Peter MacCallum Cancer Centre, St. Andrews Place, East Melbourne, Melbourne, Australia.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-10-3994DOI Listing
March 2011

Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation.

J Exp Med 2007 Oct 1;204(11):2603-14. Epub 2007 Oct 1.

Department of Inflammation, 2Department of Pathology, 3Department of Biostatistics, Amgen, Seattle, WA 98119, USA.

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http://dx.doi.org/10.1084/jem.20070157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118475PMC
October 2007