Jennifer A Foden

Jennifer A Foden

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Jennifer A Foden

Jennifer A Foden

Publications by authors named "Jennifer A Foden"

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing.

Nat Biotechnol 2014 Jun 25;32(6):569-76. Epub 2014 Apr 25.

1] Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [2] Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [3] Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [4] Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nbt.2908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090141PMC
June 2014

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.

Nucleic Acids Res 2013 Oct 14;41(19):e181. Epub 2013 Aug 14.

Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129, USA, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA 02129, USA, Department of Pathology, Harvard Medical School, Boston, MA 02115, USA, Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 01238, USA, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA and Howard Hughes Medical Institute, Chevy Chase, MD 02815, USA.

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http://dx.doi.org/10.1093/nar/gkt716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799455PMC
October 2013

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.

Nat Biotechnol 2013 Sep 23;31(9):822-6. Epub 2013 Jun 23.

1] Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [2] Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [3] Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [4] Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nbt.2623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773023PMC
September 2013

FLASH assembly of TALENs for high-throughput genome editing.

Nat Biotechnol 2012 May;30(5):460-5

Molecular Pathology Unit, Center for Computational and Integrative Biology, and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://www.nature.com/articles/nbt.2170
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http://dx.doi.org/10.1038/nbt.2170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558947PMC
May 2012