Jennie R Lill

Jennie R Lill

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Jennie R Lill

Jennie R Lill

Publications by authors named "Jennie R Lill"

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62Publications

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Microwave-Assisted Protein Staining, Destaining, and In-Gel/In-Solution Digestion of Proteins.

Methods Mol Biol 2018 ;1853:75-86

Biomolecular Mass Spectrometry Laboratory, EPFL-FSB-ISIC LSMB, Lausanne, Switzerland.

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http://dx.doi.org/10.1007/978-1-4939-8745-0_10DOI Listing
May 2019

Hippo Pathway in Cancer: Aberrant Regulation and Therapeutic Opportunities.

Trends Cancer 2019 05 16;5(5):297-307. Epub 2019 May 16.

Department of Discovery Oncology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2019.04.001DOI Listing
May 2019

MHC class I presented antigens from malignancies: A perspective on analytical characterization & immunogenicity.

J Proteomics 2019 01 24;191:48-57. Epub 2018 Apr 24.

Department of Microchemistry, Proteomics & Lipidomics, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2018.04.021DOI Listing
January 2019

MAPPs for the identification of immunogenic hotspots of biotherapeutics; an overview of the technology and its application to the biopharmaceutical arena.

Expert Rev Proteomics 2018 09 17;15(9):733-748. Epub 2018 Sep 17.

b Department of Microchemistry , Proteomics & Lipidomics, Genentech Inc ., San Francisco , CA , USA.

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http://dx.doi.org/10.1080/14789450.2018.1521279DOI Listing
September 2018

De Novo MS/MS Sequencing of Native Human Antibodies.

J Proteome Res 2017 01 2;16(1):45-54. Epub 2016 Nov 2.

Department of Computer Science and Engineering, University of California, San Diego , 9500 Gilman Drive, Mail Code 0404, La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574256PMC
January 2017

Building proteomic tool boxes to monitor MHC class I and class II peptides.

Proteomics 2017 01;17(1-2)

Department of Proteomics & Biological Resources, Genentech Inc., San Francisco, CA, USA.

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http://dx.doi.org/10.1002/pmic.201600061DOI Listing
January 2017

RIPK1 inhibits ZBP1-driven necroptosis during development.

Nature 2016 12 7;540(7631):129-133. Epub 2016 Nov 7.

Department of Physiological Chemistry, Genentech, 1 DNA Way, South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1038/nature20559DOI Listing
December 2016

Characterization of Chain Pairing Variants of Bispecific IgG Expressed in a Single Host Cell by High-Resolution Native and Denaturing Mass Spectrometry.

Anal Chem 2016 12 8;88(24):12122-12127. Epub 2016 Dec 8.

Departments of Proteomics & Biological Resources, ‡Antibody Engineering, and §Protein Chemistry, Genentech, Inc. , South San Francisco, California 94080, United States.

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http://dx.doi.org/10.1021/acs.analchem.6b02866DOI Listing
December 2016

Rapid, semi-automated protein terminal characterization using ISDetect.

Nat Biotechnol 2016 08;34(8):811-3

Department of Protein Chemistry, Genentech, Inc., South San Francisco, California, USA.

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http://dx.doi.org/10.1038/nbt.3621DOI Listing
August 2016

Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress.

PLoS One 2015 18;10(6):e0130635. Epub 2015 Jun 18.

Cell Death and Survival Networks Program, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America; Pharma Research and Early Development (pRED), Roche, Basel, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130635PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472728PMC
May 2016

Proteomic tools for the characterization of cell death mechanisms in drug discovery.

Proteomics Clin Appl 2015 Aug 3;9(7-8):671-83. Epub 2015 May 3.

Department of Protein Chemistry, Genentech, Inc., South San Francisco, CA, USA.

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http://dx.doi.org/10.1002/prca.201400151DOI Listing
August 2015

SUMO deconjugation is required for arsenic-triggered ubiquitylation of PML.

Sci Signal 2015 Jun 9;8(380):ra56. Epub 2015 Jun 9.

Cell Death and Survival Networks Program, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1126/scisignal.aaa3929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603552PMC
June 2015

HSP105 recruits protein phosphatase 2A to dephosphorylate β-catenin.

Mol Cell Biol 2015 Apr 2;35(8):1390-400. Epub 2015 Feb 2.

Department of Discovery Oncology, Genentech, Inc., South San Francisco, California, USA

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http://dx.doi.org/10.1128/MCB.01307-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372692PMC
April 2015

Complementary methods for the identification of substrates of proteolysis.

Methods Enzymol 2014 ;544:359-80

Department of Protein Chemistry, Genentech Inc., South San Francisco, California, USA. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-417158-9.00014-5DOI Listing
February 2015

Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry.

Mol Cell Proteomics 2014 Sep 7;13(9):2450-66. Epub 2014 Jul 7.

From the ‡Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104;

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http://dx.doi.org/10.1074/mcp.O113.036459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159661PMC
September 2014

Endosomes are specialized platforms for bacterial sensing and NOD2 signalling.

Nature 2014 May 30;509(7499):240-4. Epub 2014 Mar 30.

Genentech, 1 DNA Way, South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1038/nature13133DOI Listing
May 2014

Combinatorial approach for large-scale identification of linked peptides from tandem mass spectrometry spectra.

Mol Cell Proteomics 2014 Apr 3;13(4):1128-36. Epub 2014 Feb 3.

Bioinformatics Program, University of California, San Diego, La Jolla, California;

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http://dx.doi.org/10.1074/mcp.M113.035758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977190PMC
April 2014

Toward understanding ubiquitin-modifying enzymes: from pharmacological targeting to proteomics.

Trends Pharmacol Sci 2014 Apr 6;35(4):187-207. Epub 2014 Apr 6.

Department of Early Discovery Biochemistry, Genentech, Inc., 1 DNA Way, M/S 40, South San Francisco, CA 94080, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2014.01.005DOI Listing
April 2014

A turn-key approach for large-scale identification of complex posttranslational modifications.

J Proteome Res 2014 Mar 29;13(3):1190-9. Epub 2014 Jan 29.

Bioinformatics Program, ∥Skaggs School of Pharmacy and Pharmaceutical Sciences, ⊥Center for Computational Mass Spectrometry, and ¶Department of Computer Science and Engineering, University of California, San Diego , La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/pr400368uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993922PMC
March 2014

A Novel Peptide-Based SILAC Method to Identify the Posttranslational Modifications Provides Evidence for Unconventional Ubiquitination in the ER-Associated Degradation Pathway.

Int J Proteomics 2013 3;2013:857918. Epub 2013 Feb 3.

Division of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3200, USA ; Department of Protein Chemistry, Genentech Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1155/2013/857918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574754PMC
February 2013

The chromosome-centric human proteome project: a call to action.

J Proteome Res 2013 Jan 21;12(1):28-32. Epub 2012 Dec 21.

Thermo Fisher Scientific, Life Science Mass Spectrometry, San Jose, California 95134, United States.

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http://pubs.acs.org/doi/10.1021/pr300933p
Publisher Site
http://dx.doi.org/10.1021/pr300933pDOI Listing
January 2013

Microwave-assisted protein staining, destaining, and in-gel/in-solution digestion of proteins.

Methods Mol Biol 2012 ;869:521-32

Genentech, Inc., South San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-61779-821-4_46DOI Listing
September 2012

Complementary proteomic tools for the dissection of apoptotic proteolysis events.

J Proteome Res 2012 May 29;11(5):2947-54. Epub 2012 Mar 29.

Department of Protein Chemistry, Genentech Inc, 1 DNA Way, South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1021/pr300035kDOI Listing
May 2012

Comparative analysis of techniques to purify plasma membrane proteins.

J Biomol Tech 2010 Sep;21(3):108-15

Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922835PMC
September 2010

Template proteogenomics: sequencing whole proteins using an imperfect database.

Mol Cell Proteomics 2010 Jun 17;9(6):1260-70. Epub 2010 Feb 17.

Department of Computer Science, University of California, San Diego, San Diego, California 92093, USA.

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http://dx.doi.org/10.1074/mcp.M900504-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877985PMC
June 2010

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.

Nature 2010 Jan 20;463(7277):103-7. Epub 2009 Dec 20.

Department of Physiological Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1038/nature08646DOI Listing
January 2010

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling.

Cell 2009 May 7;137(4):721-35. Epub 2009 May 7.

Department of Molecular Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1016/j.cell.2009.03.015DOI Listing
May 2009

The double-histone-acetyltransferase complex ATAC is essential for mammalian development.

Mol Cell Biol 2009 Mar 22;29(5):1176-88. Epub 2008 Dec 22.

Department of Pathology, Genentech Inc., 1 DNA Way MS 72B, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1128/MCB.01599-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643826PMC
March 2009

Recent developments in microwave-assisted protein chemistries - can this be integrated into the drug discovery and validation process?

Drug Discov Today 2008 Dec 7;13(23-24):1075-81. Epub 2008 Nov 7.

Genentech Inc., Department of Protein Chemistry, 1 DNA Way, MS 413A, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1016/j.drudis.2008.08.007DOI Listing
December 2008

Targeted mass spectrometric strategy for global mapping of ubiquitination on proteins.

Rapid Commun Mass Spectrom 2007 ;21(20):3357-64

Applied Biosystems, Foster City, CA 94404, USA.

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http://dx.doi.org/10.1002/rcm.3227DOI Listing
November 2007

Applications of microwave-assisted proteomics in biotechnology.

Comb Chem High Throughput Screen 2007 Nov;10(9):751-65

Protein Chemistry Department, Genentech Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.2174/138620707783018504DOI Listing
November 2007

Microwave-assisted proteomics.

Mass Spectrom Rev 2007 Sep-Oct;26(5):657-71

Protein Chemistry Department, Genentech Inc, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1002/mas.20140DOI Listing
October 2007

De novo proteomic sequencing of a monoclonal antibody raised against OX40 ligand.

Anal Biochem 2006 May 21;352(1):77-86. Epub 2006 Feb 21.

Department of Protein Chemistry, Genentech, South San Francisco, CA 94080, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000326970600088
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http://dx.doi.org/10.1016/j.ab.2006.02.001DOI Listing
May 2006

Rapid on-membrane proteolytic cleavage for Edman sequencing and mass spectrometric identification of proteins.

Electrophoresis 2005 Nov;26(22):4243-51

Department of Protein Chemistry, Genentech Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1002/elps.200500206DOI Listing
November 2005