Jeffrey Weber

Jeffrey Weber

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Jeffrey Weber

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Melanoma Prognosis - Accuracy of the American Joint Committee on Cancer Staging Manual Eighth Edition.

J Natl Cancer Inst 2020 Jan 24. Epub 2020 Jan 24.

Ronald O. Perelman Department of Dermatology, NYU Langone School of Medicine.

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http://dx.doi.org/10.1093/jnci/djaa008DOI Listing
January 2020

Autoimmune genetic risk variants as germline biomarkers of response to melanoma immune-checkpoint inhibition.

Cancer Immunol Immunother 2019 Jun 12;68(6):897-905. Epub 2019 Mar 12.

Laura and Issac Perlmutter Cancer Center, New York University School of Medicine, 522 First Avenue, New York, NY, 10016, USA.

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http://dx.doi.org/10.1007/s00262-019-02318-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531317PMC
June 2019

Surgical Treatment of Subtalar Joint Instability: Safety and Accuracy of a New Technique in a Cadaver Model.

J Foot Ankle Surg 2020 Jan - Feb;59(1):38-43

Attending, Orthopedic Foot and Ankle Center, Worthington, OH. Electronic address:

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http://dx.doi.org/10.1053/j.jfas.2019.07.003DOI Listing
June 2019

Osteochondral Defect of the Calcaneocuboid Joint: A Case Study.

J Foot Ankle Surg 2019 May 23;58(3):567-572. Epub 2019 Feb 23.

Fellowship-Trained Foot and Ankle Surgeon, Orthopedic Foot and Ankle Center, Westerville, OH.

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http://dx.doi.org/10.1053/j.jfas.2018.09.013DOI Listing
May 2019

Predictive Biomarkers for Checkpoint Immunotherapy: Current Status and Challenges for Clinical Application.

Cancer Immunol Res 2018 10;6(10):1122-1128

Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, New York.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0214DOI Listing
October 2018

Immunotherapy in the adjuvant setting for high-risk melanoma.

Authors:
Jeffrey S Weber

Clin Adv Hematol Oncol 2018 Aug;16(8):546-548

NYU School of Medicine, New York, New York.

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August 2018

Durable Complete Response After Discontinuation of Pembrolizumab in Patients With Metastatic Melanoma.

J Clin Oncol 2018 06 28;36(17):1668-1674. Epub 2017 Dec 28.

Caroline Robert, Gustave Roussy Cancer Campus and Paris Sud University, Villejuif Paris-Sud, France; Antoni Ribas, University of California, Los Angeles; Omid Hamid, The Angeles Clinic and Research Institute, Los Angeles; Adil Daud, University of California, San Francisco, San Francisco, CA; Jedd D. Wolchok, Ludwig Center, Memorial Sloan Kettering Cancer Center, New York, NY; Anthony M. Joshua, The Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Wen-Jen Hwu, The University of Texas MD Anderson Cancer Center, Houston; Amita Patnaik, South Texas Accelerated Research Therapeutics, San Antonio, TX; Jeffrey S. Weber, H Lee Moffitt Cancer Center, Tampa; Richard W. Joseph, Mayo Clinic Cancer Center-Florida, Jacksonville, FL; Tara C. Gangadhar, Abramson Cancer Center at the University of Pennsylvania, Philadelphia; Hassane Zarour, UPMC Hillman Cancer Center, Pittsburgh, PA; Roxana Dronca, Mayo Clinic, Rochester, MN; Richard Kefford, Crown Princess Mary Cancer Centre, Westmead Hospital, Westmead; Melanoma Institute Australia, Wollstonecraft; and Macquarie University, MQ Health, Health Sciences Centre; Peter Hersey, University of Sydney, Sydney, New South Wales, Australia; Jin Zhang, James Anderson, Scott J. Diede, and Scot Ebbinghaus, Merck & Co., Inc., Kenilworth, NJ; F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA.

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http://ascopubs.org/doi/10.1200/JCO.2017.75.6270
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http://dx.doi.org/10.1200/JCO.2017.75.6270DOI Listing
June 2018

Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline.

J Clin Oncol 2018 06 14;36(17):1714-1768. Epub 2018 Feb 14.

Julie R. Brahmer, Johns Hopkins Kimmel Cancer Center; Jennifer S. Mammen, Johns Hopkins University, Baltimore, MD; Christina Lacchetti, American Society of Clinical Oncology, Alexandria; Alexander Spira, Virginia Cancer Specialists and US Oncology Research, Fairfax, VA; Bryan J. Schneider, University of Michigan Health System, Ann Arbor, MI; Michael B. Atkins, Georgetown Lombardi Comprehensive Cancer Center; Cristina A. Reichner, Georgetown University; Laura D. Porter, Colon Cancer Alliance; Washington, DC; Kelly J. Brassil, Aung Naing, Loretta J. Nastoupil, Maria E. Suarez-Almazor, and Yinghong Wang, MD Anderson Cancer Center, Houston, TX; Jeffrey M. Caterino, The Ohio State University Wexner Medical Center, Columbus, OH; Ian Chau, The Royal Marsden Hospital and Institute of Cancer Research, London and Surrey, United Kingdom; Marc S. Ernstoff and Igor Puzanov, Roswell Park Cancer Institute, Buffalo; Bianca D. Santomasso and Jedd D. Wolchok, Memorial Sloan Kettering Cancer Center; Jeffrey S. Weber, New York University Langone Medical Center, New York, NY; Pamela Ginex, Oncology Nursing Society, Pittsburgh, PA; Jennifer M. Gardner, Seattle Cancer Care Alliance and University of Washington, Seattle, WA; Sigrun Hallmeyer, Oncology Specialists SC, Park Ridge, IL; Jennifer Holter Chakrabarty, University of Oklahoma, Stephenson Cancer Center, Oklahoma City, OK; Natasha B. Leighl, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; David F. McDermott, Beth Israel Deaconess Medical Center; Carole Seigel, Massachusetts General Hospital Cancer Center, Boston, MA; John A. Thompson, Seattle Cancer Care Alliance, University of Washington, and the Fred Hutchinson Cancer Research Center, Seattle, WA; and Tanyanika Phillips, CHRISTUS St Frances Cabrini Cancer Center, Alexandria, LA.

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http://dx.doi.org/10.1200/JCO.2017.77.6385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481621PMC
June 2018

Reply to Improving the survival of patients with American Joint Committee on Cancer stage III and IV melanoma.

Cancer 2018 05 15;124(10):2254-2255. Epub 2018 Mar 15.

Georgetown Lombardi Comprehensive Cancer Center, Medstar Georgetown University Hospital, Washington, DC.

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http://dx.doi.org/10.1002/cncr.31261DOI Listing
May 2018

Challenging Cases: Management of Immune-Related Toxicity.

Authors:
Jeffrey S Weber

Am Soc Clin Oncol Educ Book 2018 May;38:179-183

From the Laura and Isaac Perlmutter Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/EDBK_209557DOI Listing
May 2018

Long-Term Outcomes in Patients With BRAF V600-Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib.

J Clin Oncol 2018 03 9;36(7):667-673. Epub 2017 Oct 9.

Georgina V. Long, University of Sydney, and Royal North Shore Hospital; Richard Kefford, Macquarie University, Sydney, and Westmead Hospital, Westmead, New South Wales; Jonathan Cebon, Ludwig Institute for Cancer Research, Melbourne, Victoria, Australia; Zeynep Eroglu, Moffitt Cancer Center, Tampa, FL; Jeffrey Infante, Tennessee Oncology; Douglas B. Johnson, Vanderbilt-Ingram Cancer Center, Nashville, TN; Sapna Patel, The University of Texas MD Anderson Cancer Center, Houston, TX; Adil Daud, University of California, San Francisco, San Francisco; Omid Hamid, The Angeles Clinic and Research Institute, Los Angeles, CA; Rene Gonzalez, University of Colorado, Denver, CO; Lynn Schuchter, University of Pennsylvania, Philadelphia, PA; William Sharfman, Sidney Kimmel Cancer Center, Baltimore, MD; Robert McWilliams, Mayo Clinic, Rochester, MN; Mario Sznol, Yale University, New Haven, CT; Suman Redhu, Eduard Gasal, and Bijoyesh Mookerjee, Novartis, East Hanover, NJ; Jeffrey Weber, New York University Langone Medical Center, New York, NY; and Keith T. Flaherty, Dana-Farber/Harvard Cancer Center, Boston, MA.

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http://ascopubs.org/doi/10.1200/JCO.2017.74.1025
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http://dx.doi.org/10.1200/JCO.2017.74.1025DOI Listing
March 2018

Recent advances in adjuvant therapy for patients with melanoma.

Authors:
Jeffrey Weber

ESMO Open 2018 23;3(3):e000337. Epub 2018 Mar 23.

NYU Langone Medical Center, Laura and Isaac Perlmutter Cancer Center, New York, USA.

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http://dx.doi.org/10.1136/esmoopen-2018-000337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890053PMC
March 2018

Overall Survival in Patients With Advanced Melanoma Who Received Nivolumab Versus Investigator's Choice Chemotherapy in CheckMate 037: A Randomized, Controlled, Open-Label Phase III Trial.

J Clin Oncol 2018 02 3;36(4):383-390. Epub 2017 Jul 3.

James Larkin, Royal Marsden NHS Foundation Trust, London; Paul Lorigan, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; David Minor, California Pacific Medical Center Research Institute; Adil Daud, University of California San Francisco, San Francisco; Bartosz Chmielowski, University of California, Santa Monica, CA; Sandra D'Angelo, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College; Jeffrey Weber, Perlmutter Cancer Center at New York University-Langone Medical Center, New York; Nikhil Khushalani, Roswell Park Cancer Institute, Buffalo, NY; Gerald Linette, Washington University, St. Louis, MO; Christopher D. Lao, University of Michigan, Ann Arbor, MI; Kenneth Grossmann, Huntsman Cancer Institute, Salt Lake City, UT; Mario Sznol, Yale Comprehensive Cancer Center, New Haven, CT; Jeffrey Sosman, Northwestern University, Chicago, IL; Dana Walker, George Kong, and Christine Horak, Bristol-Myers Squibb, Princeton, NJ; Bart Neyns, University Hospital, Vrije Universiteit Brussel, Brussels, Belgium; Michael Smylie, Cross Cancer Institute, Edmonton, Alberta; Wilson H. Miller Jr, Jewish General Hospital and Segal Cancer Centre, McGill University, Montreal, Quebc, Canada; Ralf Gutzmer, Medizinische Hochschule Hannover, Hannover; Jessica C. Hassel, Nationale Centrum für Tumorerkrankungen Heidelberg, Heidelberg; Dirk Schadendorf, University Hospital Essen, Essen, Germany; and Christoph Hoeller, Medical University of Vienna, Wien, Austria.

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http://dx.doi.org/10.1200/JCO.2016.71.8023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804912PMC
February 2018

Adjuvant Therapy in Resected Melanoma.

N Engl J Med 2018 02;378(7):680

Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy

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http://dx.doi.org/10.1056/NEJMc1716071DOI Listing
February 2018

Rare Dissipative Transitions Punctuate the Initiation of Chemical Denaturation in Proteins.

Biophys J 2018 02;114(4):812-821

IBM Thomas J. Watson Research Center, Yorktown Heights, New York; Department of Chemistry, Columbia University, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.12.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985007PMC
February 2018

Improved survival of patients with melanoma brain metastases in the era of targeted BRAF and immune checkpoint therapies.

Cancer 2018 01 12;124(2):297-305. Epub 2017 Oct 12.

Georgetown Lombardi Comprehensive Cancer Center, Medstar Georgetown University Hospital, Washington, DC.

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http://dx.doi.org/10.1002/cncr.30946DOI Listing
January 2018

Molecular mechanism of Gd@C(OH) increasing collagen expression: Implication for encaging tumor.

Biomaterials 2018 Jan 16;152:24-36. Epub 2017 Oct 16.

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.10.027DOI Listing
January 2018

New Fixation Methods for the Treatment of the Diabetic Foot: Beaming, External Fixation, and Beyond.

Clin Podiatr Med Surg 2018 Jan 3;35(1):63-76. Epub 2017 Oct 3.

Orthopedic Foot and Ankle Center, 300 Polaris Parkway, Westerville, OH 43082, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cpm.2017.08.001DOI Listing
January 2018

Biomarkers for Checkpoint Inhibition.

Authors:
Jeffrey S Weber

Am Soc Clin Oncol Educ Book 2017 ;37:205-209

From the Laura and Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY.

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http://dx.doi.org/10.1200/EDBK_175463DOI Listing
December 2017

Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma.

N Engl J Med 2017 11 10;377(19):1824-1835. Epub 2017 Sep 10.

From New York University Perlmutter Cancer Center, New York (J.W.); Papa Giovanni XXIII Cancer Center Hospital, Bergamo (M. Mandala), Medical Oncology, National Cancer Institute, Milan (M.D.V.), Oncology Institute of Veneto Istituti di Ricovero e Cura a Carattere Scientifico, Padua (V.C.-S.), Center for Immuno-Oncology, University Hospital of Siena, Istituto Toscano Tumori, Siena (M. Maio), Ospedale Policlinico San Martino, Genoa (P.Q.), and Istituto Nazionale Tumori Fondazione Pascale, Naples (P.A.A.) - all in Italy; National and Kapodistrian University of Athens, Athens (H.J.G.); Hospital Clinic de Barcelona, Barcelona (A.M.A.), and General University Hospital Gregorio Marañón, Madrid (I.M.-R.) - both in Spain; Texas Oncology-Baylor Cancer Center, Dallas (C.L.C.); Hospices Civils de Lyon, Pierre Bénite (S.D.), Aix-Marseille University, Hospital de la Timone, Marseille (J.-J.G.), Institut Universitaire du Cancer de Toulouse and Centre Hospitalier Universitaire (CHU), Toulouse (N.M.), Université Lille, INSERM Unité 1189, CHU Lille, Lille (L.M.), and Assistance Publique-Hôpitaux de Paris, Dermatology and Centres d'Investigation Clinique, INSERM Unité 976, Hôpital Saint Louis, Université Paris Diderot, Paris (C.L.) - all in France; Oncology Center Sf. Nectarie, Craiova, Romania (M. Schenker); Princess Margaret Cancer Centre, University of Toronto, Toronto (M.O.B.), and Cross Cancer Institute, Edmonton, AB (M. Smylie) - both in Canada; the Department of Oncology, University of Oxford, Oxford (M.R.M.), and Royal Marsden NHS Foundation Trust, London (J.L.) - both in the United Kingdom; Gallipoli Medical Research Foundation and University of Queensland, Queensland, VIC (V.A.), and Melanoma Institute Australia, University of Sydney, and Royal North Shore and Mater Hospitals, Sydney (G.V.L.) - all in Australia; University of Colorado, Denver (R.G.); Winship Cancer Institute, Emory University School of Medicine, Atlanta (R.R.K.); Georgetown-Lombardi Comprehensive Cancer Center, Washington DC (M.B.A.); University of Washington, Seattle (S.B.); Maria Sklodowska-Curie Institute-Oncology Center, Warsaw, Poland (P.R.); Nagoya University Graduate School of Medicine, Nagoya (K.Y.), and the National Cancer Center Hospital, Tokyo (N.Y.) - both in Japan; Seoul National University Hospital, Seoul, South Korea (T.M.K.); and Bristol-Myers Squibb, Princeton, NJ (V.P, J.S., A.Q.).

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http://dx.doi.org/10.1056/NEJMoa1709030DOI Listing
November 2017

Phosphatidylserine-Induced Conformational Modulation of Immune Cell Exhaustion-Associated Receptor TIM3.

Sci Rep 2017 10 19;7(1):13579. Epub 2017 Oct 19.

Computational Biology Center, IBM Thomas J. Watson Research Center, 1101 Kitchawan Rd, Yorktown Heights, New York, 10598, USA.

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http://dx.doi.org/10.1038/s41598-017-14064-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648779PMC
October 2017

Novel Checkpoints and Cosignaling Molecules in Cancer Immunotherapy.

Cancer J 2017 Jan/Feb;23(1):23-31

From the Laura and Isaac Perlmutter Cancer Center, NYU-Langone Medical Center, New York, NY.

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http://dx.doi.org/10.1097/PPO.0000000000000241DOI Listing
August 2017

Reply to F. Liang et al.

J Clin Oncol 2017 06 6;35(17):1968. Epub 2017 Mar 6.

Jeffrey S. Weber, NYU Langone Medical Center, New York, NY; and Joel Jiang, Bristol-Myers Squibb, Princeton, NJ.

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http://dx.doi.org/10.1200/JCO.2017.72.2645DOI Listing
June 2017

PD-1 and PD-L1 antibodies in cancer: current status and future directions.

Cancer Immunol Immunother 2017 May 17;66(5):551-564. Epub 2017 Feb 17.

Laura and Isaac Perlmutter Cancer Center, NYU Langone Medical Center, 522 First Avenue, 1310 Smilow Research Building, New York, NY, 10016, USA.

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http://dx.doi.org/10.1007/s00262-017-1954-6DOI Listing
May 2017

Directional mechanical stability of Bacteriophage φ29 motor's 3WJ-pRNA: Extraordinary robustness along portal axis.

Sci Adv 2017 May 26;3(5):e1601684. Epub 2017 May 26.

Institute of Quantitative Biology and Department of Physics, Zhejiang University, Hangzhou, Zhejiang 310027, China.

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http://dx.doi.org/10.1126/sciadv.1601684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446216PMC
May 2017

Safety Profile of Nivolumab Monotherapy: A Pooled Analysis of Patients With Advanced Melanoma.

J Clin Oncol 2017 Mar 14;35(7):785-792. Epub 2016 Nov 14.

Jeffrey S. Weber, H. Lee Moffitt Cancer Center, Tampa, FL; F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Jedd D. Wolchok, Memorial Sloan Kettering Cancer Center, New York, NY; Suzanne L. Topalian, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Mario Sznol, Yale University School of Medicine and Smilow Cancer Center, Yale-New Haven Hospital, New Haven, CT; Hewei Li, Ian M. Waxman, and Joel Jiang, Bristol-Myers Squibb, Princeton, NJ; Dirk Schadendorf, University of Essen, Essen, Germany; James Larkin, Royal Marsden National Health Service Foundation Trust, London, United Kingdom; Georgina V. Long, Melanoma Institute Australia and University of Sydney, Sydney, New South Wales, Australia; and Caroline Robert, Gustave Roussy and Paris-Sud University, Villejuif-Paris Sud, France.

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http://dx.doi.org/10.1200/JCO.2015.66.1389DOI Listing
March 2017

Graphene-Induced Pore Formation on Cell Membranes.

Sci Rep 2017 02 20;7:42767. Epub 2017 Feb 20.

Institute of Quantitative Biology and Medicine, SRMP and RAD-X, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China.

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http://dx.doi.org/10.1038/srep42767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5317030PMC
February 2017

PEGylated graphene oxide elicits strong immunological responses despite surface passivation.

Nat Commun 2017 02 24;8:14537. Epub 2017 Feb 24.

State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, PR China.

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http://dx.doi.org/10.1038/ncomms14537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333105PMC
February 2017

Reaffirming and Clarifying the American Society of Clinical Oncology's Policy Statement on the Critical Role of Phase I Trials in Cancer Research and Treatment.

J Clin Oncol 2017 01 28;35(2):139-140. Epub 2016 Nov 28.

Jeffrey S. Weber, New York University Langone Medical Center, New York, NY; Laura A. Levit, American Society of Clinical Oncology, Alexandria, VA; Peter C. Adamson, The Children's Hospital of Philadelphia, Philadelphia, PA; Suanna S. Bruinooge, American Society of Clinical Oncology, Alexandria, VA; Howard A. Burris III, Sarah Cannon Research Institute, Nashville, TN; Michael A. Carducci, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD; Adam P. Dicker, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA; Mithat Gönen, Memorial Sloan Kettering Cancer Center, New York, NY; Stephen M. Keefe, University of Pennsylvania, Philadelphia, PA; Michael A. Postow, Memorial Sloan Kettering Cancer Center, New York, NY; Michael A. Thompson, Aurora Health Care, Milwaukee, WI; David M. Waterhouse, Oncology Hematology Care, Cincinnati, OH; Susan L. Weiner, Children's Cause for Cancer Advocacy, Washington, DC; and Lynn M. Schuchter, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2016.70.4692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559890PMC
January 2017

Efficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma: A Pooled Analysis.

J Clin Oncol 2017 Jan 7;35(2):226-235. Epub 2016 Nov 7.

Sandra P. D'Angelo, Alexander N. Shoushtari, and Jedd D. Wolchok, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY; James Larkin, Royal Marsden Hospital, London; Paul Lorigan, University of Manchester, Manchester, United Kingdom; Jeffrey A. Sosman, Vanderbilt University Medical Center, Nashville, TN; Celeste Lebbé, Saint-Louis Hospital, Institut National de la Santé et de la Recherche Médicale U976, Université Paris Diderot, Paris; Julie Charles, Grenoble University Hospital, Grenoble Alps University, Grenoble, France; Benjamin Brady, Cabrini Health, Melbourne, Australia; Bart Neyns, Universitair Ziekenhuis Brussel, Brussels, Belgium; Henrik Schmidt, Århus University, Åarhus, Denmark; Jessica C. Hassel, University Hospital Heidelberg, Heidelberg; Peter Mohr, Elbe Kliniken Buxtehude, Buxtehude; Martin Kaatz, SRH Waldklinikum Gera, University Hospital Jena, Jena, Germany; F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Kerry J. Savage, BC Cancer Agency, University of British Columbia, Vancouver; Wilson H. Miller Jr, Lady Davis Institute and Jewish General Hospital, McGill University, Montreal, Canada; Ivan Marquez-Rodas, Hospital General Universitario Gregorio Marañón, Madrid, Spain; Mario Sznol, Yale University School of Medicine and Smilow Cancer Center, Yale-New Haven Hospital, New Haven, CT; Jeffrey S. Weber, Moffitt Cancer Center, Tampa, FL; and Mary Ruisi and Joel Jiang, Bristol-Myers Squibb, Princeton, NJ.

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http://ascopubs.org/doi/10.1200/JCO.2016.67.9258
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http://dx.doi.org/10.1200/JCO.2016.67.9258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559888PMC
January 2017

Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in Melanoma.

J Clin Oncol 2016 12 31;34(34):4102-4109. Epub 2016 Oct 31.

Adil I. Daud, University of California, San Francisco, San Francisco; Antoni Ribas, University of California, Los Angeles; Omid Hamid, The Angeles Clinic and Research Institute, Los Angeles; Charlotte Roach and Grant Toland, Dako North America, Carpinteria, CA; Jedd D. Wolchok, Memorial Sloan Kettering Cancer Center, New York, NY; Wen-Jen Hwu, The University of Texas MD Anderson Cancer Center, Houston; Amita Patnaik, South Texas Accelerated Research Therapeutics, San Antonio, TX; Jeffrey S. Weber, H. Lee Moffitt Cancer Center, Tampa; Richard Joseph, Mayo Clinic, Jacksonville, FL; F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Tara C. Gangadhar, Abramson Cancer Center at the University of Pennsylvania, Philadelphia; Hassane Zarour, University of Pittsburgh, Pittsburgh, PA; Roxana Dronca, Mayo Clinic, Rochester, MN; Jared K. Lunceford, Xiaoyun Nicole Li, Kenneth Emancipator, Marisa Dolled-Filhart, S. Peter Kang, and Scot Ebbinghaus, Merck & Co, Kenilworth, NJ; Caroline Robert, Gustave Roussy and Paris-Sud University, Villejuif, France; Anthony M. Joshua, Princess Margaret Cancer Centre, Toronto, ON, Canada; Richard Kefford, Crown Princess Mary Cancer Centre, Westmead Hospital and Melanoma Institute Australia; Richard Kefford, Macquarie University; and Richard Kefford and Peter Hersey, University of Sydney, Sydney, NSW, Australia.

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http://ascopubs.org/doi/10.1200/JCO.2016.67.2477
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http://dx.doi.org/10.1200/JCO.2016.67.2477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562434PMC
December 2016

A phase IB study of ipilimumab with peginterferon alfa-2b in patients with unresectable melanoma.

J Immunother Cancer 2016 20;4:85. Epub 2016 Dec 20.

Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612-9416 USA ; New York University Langone Medical Center, New York, NY USA.

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http://dx.doi.org/10.1186/s40425-016-0194-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5170897PMC
December 2016

Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy.

N Engl J Med 2016 11 7;375(19):1845-1855. Epub 2016 Oct 7.

From Gustave Roussy Cancer Campus Grand Paris, Villejuif (A.M.M.E., C.R.), Aix-Marseille University, Hôpital de La Timone, Marseille (J.-J.G.), Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Paris (C.L.), University Lille, INSERM Unité-1189, Centre Hospitalier Universitaire (CHU) Lille, Service de Dermatologie, Lille (L.M.), and CHU Lyon, Lyon (L.T.) - all in France; the Oncology Institute of Veneto-Istituto di Ricovero e Cura a Carattere Scientifico, Padua (V.C.-S.), Istituto Nazionale Tumori Fondazione G. Pascale, Naples (P.A.A.), Istituti Fisioterapici Ospitalieri, Rome (V.F.), University Hospital of Siena, Istituto Toscano Tumori, Siena (M.M.), and the European Institute of Oncology, Milan (A.T.) - all in Italy; University of Zurich Hospital, Zurich, Switzerland (R.D.); Memorial Sloan Kettering Cancer Center, New York (J.D.W.); Aarhus University Hospital, Aarhus (H.S.), and Odense University Hospital, Odense (L.B.) - both in Denmark; the Angeles Clinic and Research Institute, Los Angeles (O.H.); Oncology Specialists, Park Ridge, IL (J.M.R.); Cross Cancer Institute, Edmonton, AB, Canada (M.S.); H. Lee Moffitt Cancer Center, Tampa, FL (J.S.W.); Broomfield Hospital, Chelmsford, United Kingdom (S.T.); Universitätsklinikum Schleswig-Holstein, Kiel (A.H.), and University Hospital Heidelberg, Heidelberg (J.C.H.) - both in Germany; Dana-Farber Cancer Institute, Boston (F.S.H.); Bristol-Myers Squibb, Princeton, NJ (C.T., V.P.); and the European Organization for Research and Treatment of Cancer, Brussels (G.S., S.S.).

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http://dx.doi.org/10.1056/NEJMoa1611299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648545PMC
November 2016

Resection of Gastrointestinal Metastases in Stage IV Melanoma: Correlation with Outcomes.

Am Surg 2016 Nov;82(11):1109-1116

Department of Cutaneous Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.

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November 2016

From the Guest Editor: Adoptive Cell Therapy: Fulfilling Its Promise.

Authors:
Jeffrey S Weber

Cancer J 2015 Nov-Dec;21(6):448-9

From Donald A. Adam Comprehensive Melanoma Center, Moffitt Cancer Center, Tampa, FL.

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http://dx.doi.org/10.1097/PPO.0000000000000163DOI Listing
September 2016

Endoscopic management of a gastrocolonic fistula.

Gastrointest Endosc 2016 Sep 26;84(3):525-6. Epub 2016 Mar 26.

Western Regional Medical Center at Cancer Treatment Center of America, Goodyear, Arizona, USA; Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1016/j.gie.2016.03.1477DOI Listing
September 2016

Successful endoscopic management of a malignant ileovesicular fistula.

Gastrointest Endosc 2016 Sep 26;84(3):536-7. Epub 2016 Mar 26.

Western Regional Medical Center at Cancer Treatment Center of America, Goodyear, Arizona, USA.

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http://dx.doi.org/10.1016/j.gie.2016.03.1478DOI Listing
September 2016

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016.

Authors:
Christian Dittrich Michael Kosty Svetlana Jezdic Doug Pyle Rossana Berardi Jonas Bergh Nagi El-Saghir Jean-Pierre Lotz Pia Österlund Nicholas Pavlidis Gunta Purkalne Ahmad Awada Susana Banerjee Smita Bhatia Jan Bogaerts Jan Buckner Fatima Cardoso Paolo Casali Edward Chu Julia Lee Close Bertrand Coiffier Roisin Connolly Sarah Coupland Luigi De Petris Maria De Santis Elisabeth G E de Vries Don S Dizon Jennifer Duff Linda R Duska Alexandru Eniu Marc Ernstoff Enriqueta Felip Martin F Fey Jill Gilbert Nicolas Girard Andor W J M Glaudemans Priya K Gopalan Axel Grothey Stephen M Hahn Diana Hanna Christian Herold Jørn Herrstedt Krisztian Homicsko Dennie V Jones Lorenz Jost Ulrich Keilholz Saad Khan Alexander Kiss Claus-Henning Köhne Rainer Kunstfeld Heinz-Josef Lenz Stuart Lichtman Lisa Licitra Thomas Lion Saskia Litière Lifang Liu Patrick J Loehrer Merry Jennifer Markham Ben Markman Marius Mayerhoefer Johannes G Meran Olivier Michielin Elizabeth Charlotte Moser Giannis Mountzios Timothy Moynihan Torsten Nielsen Yuichiro Ohe Kjell Öberg Antonio Palumbo Fedro Alessandro Peccatori Michael Pfeilstöcker Chandrajit Raut Scot C Remick Mark Robson Piotr Rutkowski Roberto Salgado Lidia Schapira Eva Schernhammer Martin Schlumberger Hans-Joachim Schmoll Lowell Schnipper Cristiana Sessa Charles L Shapiro Julie Steele Cora N Sternberg Friedrich Stiefel Florian Strasser Roger Stupp Richard Sullivan Josep Tabernero Luzia Travado Marcel Verheij Emile Voest Everett Vokes Jamie Von Roenn Jeffrey S Weber Hans Wildiers Yosef Yarden

ESMO Open 2016 29;1(5):e000097. Epub 2016 Sep 29.

Department of General Medical Oncology , University Hospitals Leuven , Leuven , Belgium.

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http://dx.doi.org/10.1136/esmoopen-2016-000097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070299PMC
September 2016

Comment on the American Society of Clinical Oncology Value Statement.

J Clin Oncol 2016 08 13;34(24):2937-8. Epub 2016 Jun 13.

University of Cambridge, Cambridge; Advent Life Sciences, London, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2015.64.3692DOI Listing
August 2016

Sequential protein unfolding through a carbon nanotube pore.

Nanoscale 2016 Jun;8(24):12143-51

Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China.

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http://dx.doi.org/10.1039/c6nr00410eDOI Listing
June 2016

Evaluation of Immune-Related Response Criteria and RECIST v1.1 in Patients With Advanced Melanoma Treated With Pembrolizumab.

J Clin Oncol 2016 05 7;34(13):1510-7. Epub 2016 Mar 7.

F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Wen-Jen Hwu, The University of Texas MD Anderson Cancer Center, Houston; Amita Patnaik, South Texas Accelerated Research Therapeutics, San Antonio, TX; Richard Kefford, Westmead Hospital, Melanoma Institute Australia, and Macquarie University; Peter Hersey, University of Sydney, Sydney, Australia; Jeffrey S. Weber, H. Lee Moffitt Cancer Center, Tampa; Richard Joseph, Mayo Clinic, Jacksonville, FL; Adil Daud, University of California San Francisco, San Francisco; Omid Hamid, The Angeles Clinic and Research Institute; Antoni Ribas, University of California Los Angeles, Los Angeles, CA; Caroline Robert, Gustave-Roussy and Paris-Sud University, Villejuif-Paris-Sud, France; Tara C. Gangadhar, Abramson Cancer Center, Philadelphia, PA; Anthony M. Joshua, Princess Margaret Hospital, Toronto, Ontario, Canada; Roxana Dronca, Mayo Clinic, Rochester, MN; Darcy Hille, Dahai Xue, Xiaoyun Nicole Li, S. Peter Kang, Scot Ebbinghaus, and Andrea Perrone, Merck, Kenilworth, NJ; and Jedd D. Wolchok, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2015.64.0391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070547PMC
May 2016

Folding and Stabilization of Native-Sequence-Reversed Proteins.

Sci Rep 2016 04 26;6:25138. Epub 2016 Apr 26.

Institute of Quantitative Biology, Department of Physics, Zhejiang University, Hangzhou 310027, China.

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http://dx.doi.org/10.1038/srep25138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844985PMC
April 2016

Overall Survival and Durable Responses in Patients With BRAF V600-Mutant Metastatic Melanoma Receiving Dabrafenib Combined With Trametinib.

J Clin Oncol 2016 Mar 25;34(8):871-8. Epub 2016 Jan 25.

Georgina V. Long, Melanoma Institute Australia; The University of Sydney; Richard F. Kefford, Melanoma Institute Australia; The University of Sydney; Macquarie University, Sydney; Westmead Hospital, Westmead; Jonathan Cebon, Austin Health, Melbourne, Victoria, Australia; Jeffrey S. Weber and Ragini Kudchadkar, Moffitt Cancer Center, Tampa, FL; Jeffrey R. Infante and Howard A. Burris III, Sarah Cannon Research Institute/Tennessee Oncology; Kevin B. Kim, California Pacific Medical Center; Adil Daud, Alain Algazi, University of California, San Francisco, San Francisco; Omid Hamid, The Angeles Clinic and Research Institute, Los Angeles, CA; Rene Gonzalez, Karl Lewis, University of Colorado; Gerald S. Falchook, Sarah Cannon Research Institute at HealthONE, Denver, CO; Jeffrey A. Sosman, Igor Puzanov, Vanderbilt University Medical Center, Nashville, TN; Lynn Schuchter, University of Pennsylvania Abramson Cancer Center; Nageatte Ibrahim, Elizabeth Cunningham, Merck; Peng Sun, Amy S. Kline, Heather Del Buono, Diane Opatt McDowell, GlaxoSmithKline, Philadelphia, PA; Donald Lawrence and Kiran Patel, Incyte Corporation, Wilmington, DE; and Keith T. Flaherty, Massachusetts General Hospital Cancer Center, Boston, MA.

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http://ascopubs.org/doi/10.1200/JCO.2015.62.9345
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http://dx.doi.org/10.1200/JCO.2015.62.9345DOI Listing
March 2016

BRAF inhibition for advanced locoregional BRAF V600E mutant melanoma: a potential neoadjuvant strategy.

Melanoma Res 2016 Feb;26(1):83-7

Departments of aCutaneous Oncology bAnatomic Pathology, Moffitt Cancer Center Departments of cOncologic Sciences dSurgery, University of South Florida Morsani College of Medicine eDepartment of Pathology, Veterans Administration, Tampa, Florida fDepartment of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia gGeorgetown-Lombardi Comprehensive Cancer Center and Department of Medicine, Medstar-Georgetown University Hospital, Washington, DC, USA hUniversity of Groningen, Department of Surgical Oncology, University Medical Center Groningen, The Netherlands.

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http://dx.doi.org/10.1097/CMR.0000000000000214DOI Listing
February 2016

Tunable, Strain-Controlled Nanoporous MoS₂ Filter for Water Desalination.

ACS Nano 2016 Feb 27;10(2):1829-35. Epub 2016 Jan 27.

School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University , Suzhou 215123, China.

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http://dx.doi.org/10.1021/acsnano.5b05250DOI Listing
February 2016

Single-Walled Carbon Nanotubes Inhibit the Cytochrome P450 Enzyme, CYP3A4.

Sci Rep 2016 Feb 22;6:21316. Epub 2016 Feb 22.

Nanosafety &Nanomedicine Laboratory, Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1038/srep21316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761960PMC
February 2016

HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade.

Cancer Immunol Res 2015 Dec 21;3(12):1375-85. Epub 2015 Aug 21.

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0077-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674300PMC
December 2015

XL888 Limits Vemurafenib-Induced Proliferative Skin Events by Suppressing Paradoxical MAPK Activation.

J Invest Dermatol 2015 Oct 3;135(10):2542-2544. Epub 2015 Jun 3.

Department of Tumor Biology, The Moffitt Cancer Center, Tampa, Florida, USA; Department of Cutaneous Oncology, The Moffitt Cancer Center, Tampa, Florida, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567904PMC
October 2015

A novel form of β-strand assembly observed in Aβ(33-42) adsorbed onto graphene.

Nanoscale 2015 Oct;7(37):15341-8

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences (CAS), Beijing 100049, China.

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http://dx.doi.org/10.1039/c5nr00555hDOI Listing
October 2015

Heat dissipation guides activation in signaling proteins.

Proc Natl Acad Sci U S A 2015 Aug 3;112(33):10377-82. Epub 2015 Aug 3.

Department of Chemistry, Stanford University, Stanford, CA 94305; Simbios NIH Center for Biomedical Computation, Stanford University, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1501804112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547217PMC
August 2015

A Peptide-Coated Gold Nanocluster Exhibits Unique Behavior in Protein Activity Inhibition.

J Am Chem Soc 2015 Jul 29;137(26):8412-8. Epub 2015 Jun 29.

†CAS Key Lab for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Science, Beijing 100049, PR China.

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http://dx.doi.org/10.1021/jacs.5b00888DOI Listing
July 2015

Toxicities of Immunotherapy for the Practitioner.

J Clin Oncol 2015 Jun 27;33(18):2092-9. Epub 2015 Apr 27.

Jeffrey S. Weber, Moffitt Cancer Center, Tampa, FL; James C. Yang, National Cancer Institute, Bethesda, MD; Michael B. Atkins, Lombardi Cancer Center, Georgetown University, Washington, DC; and Mary L. Disis, The Fred Hutchinson Cancer Center, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1200/JCO.2014.60.0379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881375PMC
June 2015

Immune checkpoint protein inhibition for cancer: preclinical justification for CTLA-4 and PD-1 blockade and new combinations.

Semin Oncol 2015 Jun 16;42(3):363-77. Epub 2015 Feb 16.

Donald A. Adam Comprehensive Melanoma Research Center and Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa, FL.

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https://linkinghub.elsevier.com/retrieve/pii/S00937754150003
Publisher Site
http://dx.doi.org/10.1053/j.seminoncol.2015.02.015DOI Listing
June 2015

Reduced Cytotoxicity of Graphene Nanosheets Mediated by Blood-Protein Coating.

ACS Nano 2015 Jun 9;9(6):5713-24. Epub 2015 Jun 9.

†Institute of Quantitative Biology and Medicine, SRMP and RAD-X, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China.

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http://dx.doi.org/10.1021/nn5066606DOI Listing
June 2015

Surface Curvature Relation to Protein Adsorption for Carbon-based Nanomaterials.

Sci Rep 2015 Jun 4;5:10886. Epub 2015 Jun 4.

1] Institute of Quantitative Biology and Medicine, SRMP and RAD-X, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China [2] IBM Thomas J. Watson Research Center, Yorktown Heights, NY 10598, USA [3] Department of Chemistry, Columbia University, New York, NY 10027, USA.

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http://dx.doi.org/10.1038/srep10886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455116PMC
June 2015

Percolation-like phase transitions in network models of protein dynamics.

J Chem Phys 2015 Jun;142(21):215105

Department of Chemistry, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1063/1.4921989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457657PMC
June 2015

Potential-based dynamical reweighting for Markov state models of protein dynamics.

J Chem Theory Comput 2015 Jun;11(6):2412-20

Department of Chemistry, Stanford University , Stanford, California 94305, United States.

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http://dx.doi.org/10.1021/acs.jctc.5b00031DOI Listing
June 2015

Entropy-production-driven oscillators in simple nonequilibrium networks.

Phys Rev E Stat Nonlin Soft Matter Phys 2015 Mar 24;91(3):032136. Epub 2015 Mar 24.

Department of Chemistry, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1103/PhysRevE.91.032136DOI Listing
March 2015