Jeffrey W Dalley

Jeffrey W Dalley

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Jeffrey W Dalley

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Network failures: When incentives trigger impulsive responses.

Hum Brain Mapp 2020 Mar 9. Epub 2020 Mar 9.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/hbm.24941DOI Listing
March 2020

Shining the spotlight on the dark side of impulsivity.

Authors:
Jeffrey W Dalley

Neurosci Biobehav Rev 2019 11 17;106:7-8. Epub 2019 Jun 17.

Department of Psychology, University of Cambridge, Downing St, Cambridge CB2 3EB, UK; Department of Psychiatry, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2019.06.022DOI Listing
November 2019

Modelling Differential Vulnerability to Substance Use Disorder in Rodents: Neurobiological Mechanisms.

Handb Exp Pharmacol 2019 Nov 10. Epub 2019 Nov 10.

Department of Psychology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/164_2019_300DOI Listing
November 2019

Promoting and supporting credibility in neuroscience.

Brain Neurosci Adv 2019 Jan-Dec;3:2398212819844167. Epub 2019 Apr 10.

Department of Psychology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1177/2398212819844167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058234PMC
April 2019

Neural circuitry and mechanisms of waiting impulsivity: relevance to addiction.

Philos Trans R Soc Lond B Biol Sci 2019 02;374(1766):20180145

1 Department of Psychology, University of Cambridge , Cambridge CB2 3EB , UK.

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http://www.royalsocietypublishing.org/doi/10.1098/rstb.2018.
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http://dx.doi.org/10.1098/rstb.2018.0145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335458PMC
February 2019

Dissecting Impulsivity: Brain Mechanisms and Neuropsychiatric Implications.

Nebr Symp Motiv 2017;64:201-226

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November 2018

Bidirectional variation in glutamate efflux in the medial prefrontal cortex induced by selective positive and negative allosteric mGluR5 modulators.

J Neurochem 2018 04 12;145(2):111-124. Epub 2018 Feb 12.

Boehringer Ingelheim Pharma GmbH & Co. KG, Div. Research Germany, Biberach an der Riss, Germany.

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http://dx.doi.org/10.1111/jnc.14290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972455PMC
April 2018

Differences in trait impulsivity do not bias the response to pharmacological drug challenge in the rat five-choice serial reaction time task.

Psychopharmacology (Berl) 2018 04 26;235(4):1199-1209. Epub 2018 Jan 26.

Boehringer Ingelheim Pharma GmbH & Co. KG, Division Research Germany, Birkendorfer Strasse 65, 88397, Biberach an der Riss, Germany.

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http://dx.doi.org/10.1007/s00213-018-4836-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869891PMC
April 2018

Selective and interactive effects of D receptor antagonism and positive allosteric mGluR4 modulation on waiting impulsivity.

Neuropharmacology 2017 Sep 6;123:249-260. Epub 2017 May 6.

Boehringer Ingelheim Pharma GmbH & Co. KG, Div. Research Germany, Birkendorfer Strasse 65, 88397 Biberach an der Riss, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2017.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522528PMC
September 2017

Fractionating impulsivity: neuropsychiatric implications.

Nat Rev Neurosci 2017 02;18(3):158-171

Department of Psychology, University of Cambridge, Cambridge CB2 3EB, UK.

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http://dx.doi.org/10.1038/nrn.2017.8DOI Listing
February 2017

A welcome to from the President of the BNA and the journal's Editor-in-Chief.

Brain Neurosci Adv 2017 Jan-Dec;1:2398212816664309. Epub 2017 Jan 20.

Cambridge University, Cambridge, UK.

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http://dx.doi.org/10.1177/2398212816664309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058204PMC
January 2017

Translatable and Back-Translatable Measurement of Impulsivity and Compulsivity: Convergent and Divergent Processes.

Curr Top Behav Neurosci 2016;28:53-91

Behavioral and Clinical Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1007/7854_2015_5013DOI Listing
December 2016

Enduring, Sexually Dimorphic Impact of In Utero Exposure to Elevated Levels of Glucocorticoids on Midbrain Dopaminergic Populations.

Brain Sci 2016 Dec 30;7(1). Epub 2016 Dec 30.

Department of Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK.

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http://dx.doi.org/10.3390/brainsci7010005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297294PMC
December 2016

Counteractive effects of antenatal glucocorticoid treatment on D1 receptor modulation of spatial working memory.

Psychopharmacology (Berl) 2016 Oct 23;233(21-22):3751-3761. Epub 2016 Aug 23.

Department of Psychology, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1007/s00213-016-4405-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063912PMC
October 2016

In vivo γ-aminobutyric acid measurement in rats with spectral editing at 4.7T.

J Magn Reson Imaging 2016 06 3;43(6):1308-12. Epub 2015 Dec 3.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, UK.

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http://dx.doi.org/10.1002/jmri.25093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869682PMC
June 2016

Trait Impulsivity and Anhedonia: Two Gateways for the Development of Impulse Control Disorders in Parkinson's Disease?

Front Psychiatry 2016 30;7:91. Epub 2016 May 30.

INSERM U1216, Grenoble Institut des Neurosciences (GIN), University Grenoble Alpes , Grenoble , France.

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http://dx.doi.org/10.3389/fpsyt.2016.00091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884740PMC
June 2016

Alcohol-Preferring Rats Show Goal Oriented Behaviour to Food Incentives but Are Neither Sign-Trackers Nor Impulsive.

PLoS One 2015 22;10(6):e0131016. Epub 2015 Jun 22.

Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing St, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131016PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476783PMC
April 2016

Social dominance in rats: effects on cocaine self-administration, novelty reactivity and dopamine receptor binding and content in the striatum.

Psychopharmacology (Berl) 2016 Feb 10;233(4):579-89. Epub 2015 Nov 10.

Department of Psychology, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1007/s00213-015-4122-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726718PMC
February 2016

Oscillatory activity in the medial prefrontal cortex and nucleus accumbens correlates with impulsivity and reward outcome.

PLoS One 2014 21;9(10):e111300. Epub 2014 Oct 21.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, United Kingdom; Department of Psychology, University of Cambridge, Cambridge, United Kingdom; Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111300PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205097PMC
December 2015

Formyl peptide receptor as a novel therapeutic target for anxiety-related disorders.

PLoS One 2014 17;9(12):e114626. Epub 2014 Dec 17.

William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114626PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269406PMC
September 2015

Dissociable effects of mGluR5 allosteric modulation on distinct forms of impulsivity in rats: interaction with NMDA receptor antagonism.

Psychopharmacology (Berl) 2015 Sep 12;232(18):3327-44. Epub 2015 Jun 12.

Boehringer Ingelheim Pharma GmbH & Co. KG, Div. Research Germany, Birkendorfer Strasse 65, 88397, Biberach an der Riss, Germany.

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http://link.springer.com/content/pdf/10.1007/s00213-015-3984
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http://link.springer.com/10.1007/s00213-015-3984-0
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http://dx.doi.org/10.1007/s00213-015-3984-0DOI Listing
September 2015

Markers of serotonergic function in the orbitofrontal cortex and dorsal raphé nucleus predict individual variation in spatial-discrimination serial reversal learning.

Neuropsychopharmacology 2015 Jun 8;40(7):1619-30. Epub 2015 Jan 8.

1] Behavioural and Clinical Neuroscience Institute and Department of Psychology, University of Cambridge, Cambridge, UK [2] Department of Psychiatry, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/npp.2014.335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915245PMC
June 2015

Ramping single unit activity in the medial prefrontal cortex and ventral striatum reflects the onset of waiting but not imminent impulsive actions.

Eur J Neurosci 2015 Jun 20;41(12):1524-37. Epub 2015 Apr 20.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/ejn.12895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529742PMC
June 2015

Dopamine receptor partial agonists and addiction.

Eur J Pharmacol 2015 Apr 25;752:112-5. Epub 2015 Feb 25.

Department of Psychology, University of Cambridge, Cambridge CB2 3EB, UK; Department of Psychiatry, Addenbrooke׳s Hospital University of Cambridge, Cambridge CB2 2QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.02.025DOI Listing
April 2015

Dissociable rate-dependent effects of oral methylphenidate on impulsivity and D2/3 receptor availability in the striatum.

J Neurosci 2015 Mar;35(9):3747-55

Behavioural and Clinical Neuroscience Institute, and Department of Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom, Department of Psychiatry, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 2QQ, United Kingdom

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http://dx.doi.org/10.1523/JNEUROSCI.3890-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348181PMC
March 2015

Endocannabinoids and striatal function: implications for addiction-related behaviours.

Behav Pharmacol 2015 Feb;26(1-2):59-72

aDepartment of Pharmacology, Institute of Biological Science, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil Departments of bPsychology cPharmacology, University of Cambridge dDepartment of Psychiatry, Addenbrookes's Hospital University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1097/FBP.0000000000000109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398317PMC
February 2015

Linking ADHD, impulsivity, and drug abuse: a neuropsychological perspective.

Curr Top Behav Neurosci 2012 ;9:173-97

Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Downing St., Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1007/7854_2011_119DOI Listing
January 2015

Preface.

Curr Top Behav Neurosci 2012 ;11:v-vii

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January 2015

Impaired limbic cortico-striatal structure and sustained visual attention in a rodent model of schizophrenia.

Int J Neuropsychopharmacol 2014 Oct 31;18(2). Epub 2014 Oct 31.

Department of Psychiatry, School of Medicine, University of California San Diego, La Jolla, CA (Dr Barnes); Behavioural and Clinical Neuroscience Institute and Department of Psychology, University of Cambridge, Downing St, Cambridge UK (Drs Sawiak, Caprioli, Jupp, Mar, Fletcher, Robbins, and Dalley); Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK (Drs Sawiak and Buonincontri); Department of Psychiatry, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK (Drs Fletcher and Dalley); Manchester Pharmacy School, University of Manchester, UK (Drs Harte and Neill).

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http://dx.doi.org/10.1093/ijnp/pyu010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368881PMC
October 2014

Increased impulsivity retards the transition to dorsolateral striatal dopamine control of cocaine seeking.

Biol Psychiatry 2014 Jul 21;76(1):15-22. Epub 2013 Oct 21.

Department of Psychology, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom; Behavioural and Clinical Neuroscience Institute, Cambridge, United Kingdom; INSERM European Associated Laboratory, Poitiers.

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http://dx.doi.org/10.1016/j.biopsych.2013.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064115PMC
July 2014

Brain γ-aminobutyric acid: a neglected role in impulsivity.

Eur J Neurosci 2014 Jun 27;39(11):1921-32. Epub 2014 Jan 27.

Toronto Western Research Institute, Toronto Western Hospital and Division of Neurosurgery, University of Toronto, Toronto, ON, Canada; Mind, Brain Imaging and Neuroethics, Institute of Mental Health Research, University of Ottawa, Ottawa, ON, Canada; Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK; Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1111/ejn.12485DOI Listing
June 2014

Behavioral endophenotypes of drug addiction: Etiological insights from neuroimaging studies.

Neuropharmacology 2014 Jan 10;76 Pt B:487-97. Epub 2013 Jun 10.

Behavioral and Clinical Neuroscience Institute, Department of Psychology, University of Cambridge Downing St, Cambridge CB2 3EB, UK; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.neuropharm.2013.05.041DOI Listing
January 2014

Measuring "waiting" impulsivity in substance addictions and binge eating disorder in a novel analogue of rodent serial reaction time task.

Biol Psychiatry 2014 Jan 19;75(2):148-55. Epub 2013 Jun 19.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, United Kingdom; Department of Psychology, University of Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2013.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988873PMC
January 2014

Gamma aminobutyric acidergic and neuronal structural markers in the nucleus accumbens core underlie trait-like impulsive behavior.

Biol Psychiatry 2014 Jan 21;75(2):115-23. Epub 2013 Aug 21.

Behavioural and Clinical Neuroscience Institute and Department of Psychology, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom; Department of Psychiatry, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2013.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898085PMC
January 2014

Translating positron emission tomography studies in animals to stimulant addiction: promises and pitfalls.

Curr Opin Neurobiol 2013 Aug 9;23(4):597-606. Epub 2013 May 9.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, UK.

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http://dx.doi.org/10.1016/j.conb.2013.04.003DOI Listing
August 2013

An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'.

Bioorg Med Chem Lett 2013 Jun 28;23(11):3411-5. Epub 2013 Mar 28.

Department of Pharmaceutical and Biological Chemistry, UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, UK.

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http://dx.doi.org/10.1016/j.bmcl.2013.03.066DOI Listing
June 2013

Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex.

Eur J Neurosci 2013 May 1;37(9):1519-28. Epub 2013 Feb 1.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/ejn.12146DOI Listing
May 2013

Highly impulsive rats: modelling an endophenotype to determine the neurobiological, genetic and environmental mechanisms of addiction.

Dis Model Mech 2013 Mar 25;6(2):302-11. Epub 2013 Jan 25.

Behavioural and Cognitive Neurosciences Institute and The Department of Psychology, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1242/dmm.010934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597013PMC
March 2013

Synthesis and evaluation of 18F-FE-PEO in rodents: an 18F-labeled full agonist for opioid receptor imaging.

J Nucl Med 2013 Feb 7;54(2):299-305. Epub 2013 Jan 7.

Molecular Imaging Chemistry Laboratory, Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.

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http://jnm.snmjournals.org/cgi/doi/10.2967/jnumed.112.108688
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http://dx.doi.org/10.2967/jnumed.112.108688DOI Listing
February 2013

Single chemical entity legal highs: assessing the risk for long term harm.

Curr Drug Abuse Rev 2012 Dec;5(4):304-19

University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.2174/1874473711205040005DOI Listing
December 2012

An intra-cerebral drug delivery system for freely moving animals.

Biomed Microdevices 2012 Oct;14(5):799-809

Institut für Mikro-und Informationstechnik der Hahn-Schickard-Gesellschaft e.V.-HSG-IMIT, Wilhelm-Schickard-Str. 10, 78052 Villingen-Schwenningen, Germany.

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https://www.imtek.de/data/lehrstuehle/app/dokumente/publikat
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http://link.springer.com/10.1007/s10544-012-9659-2
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http://dx.doi.org/10.1007/s10544-012-9659-2DOI Listing
October 2012

Norepinephrine and dopamine modulate impulsivity on the five-choice serial reaction time task through opponent actions in the shell and core sub-regions of the nucleus accumbens.

Neuropsychopharmacology 2012 Aug 18;37(9):2057-66. Epub 2012 Apr 18.

Behavioral and Clinical Neuroscience Institute and Department of Experimental Psychology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/npp.2012.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398724PMC
August 2012

High anxiety is a predisposing endophenotype for loss of control over cocaine, but not heroin, self-administration in rats.

Psychopharmacology (Berl) 2012 Jul 14;222(1):89-97. Epub 2012 Jan 14.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK.

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http://dx.doi.org/10.1007/s00213-011-2626-4DOI Listing
July 2012

Compact wireless neural recording system for small animals using silicon-based probe arrays.

Conf Proc IEEE Eng Med Biol Soc 2011 ;2011:2284-7

Department of Microsystems Engineering, University of Freiburg, Germany.

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http://dx.doi.org/10.1109/IEMBS.2011.6090575DOI Listing
June 2012

Applications of positron emission tomography in animal models of neurological and neuropsychiatric disorders.

Neurosci Biobehav Rev 2012 Apr 8;36(4):1188-216. Epub 2012 Feb 8.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, CB2 3EB, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S014976341200018
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http://dx.doi.org/10.1016/j.neubiorev.2012.01.009DOI Listing
April 2012

Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex.

Psychopharmacology (Berl) 2012 Jan 19;219(2):401-10. Epub 2011 Nov 19.

Behavioural and Clinical Neuroscience Institute and Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1007/s00213-011-2572-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249210PMC
January 2012

Validation and quantification of [18F]altanserin binding in the rat brain using blood input and reference tissue modeling.

J Cereb Blood Flow Metab 2011 Dec 13;31(12):2334-42. Epub 2011 Jul 13.

Molecular Imaging Chemistry Laboratory, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/jcbfm.2011.94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323196PMC
December 2011

A wireless multi-channel recording system for freely behaving mice and rats.

PLoS One 2011 12;6(7):e22033. Epub 2011 Jul 12.

Department of Psychology and Neuroscience, Department of Neurobiology, Center for Cognitive Neuroscience, Duke University, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022033PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134473PMC
November 2011

Parkinson disease: impulsive choice-Parkinson disease and dopaminergic therapy.

Nat Rev Neurol 2011 Sep 13;7(10):541-2. Epub 2011 Sep 13.

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http://dx.doi.org/10.1038/nrneurol.2011.139DOI Listing
September 2011

What have positron emission tomography and 'Zippy' told us about the neuropharmacology of drug addiction?

Br J Pharmacol 2011 Aug;163(8):1586-604

Department of Nuclear Medicine, Ludwig-Maximilian's University, Munich, Germany.

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http://dx.doi.org/10.1111/j.1476-5381.2010.01036.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166689PMC
August 2011

Multiple extra-synaptic spillover mechanisms regulate prolonged activity in cerebellar Golgi cell-granule cell loops.

J Physiol 2011 Aug 13;589(Pt 15):3837-54. Epub 2011 Jun 13.

Department of Physiology, Development and Neuroscience, Downing Street, University of Cambridge CB2 3DY,

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http://dx.doi.org/10.1113/jphysiol.2011.207167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171889PMC
August 2011

High impulsivity predicting vulnerability to cocaine addiction in rats: some relationship with novelty preference but not novelty reactivity, anxiety or stress.

Psychopharmacology (Berl) 2011 Jun 28;215(4):721-31. Epub 2011 Jan 28.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1007/s00213-011-2167-xDOI Listing
June 2011

Selective norepinephrine reuptake inhibition by atomoxetine prevents cue-induced heroin and cocaine seeking.

Biol Psychiatry 2011 Feb 15;69(3):266-74. Epub 2010 Dec 15.

Behavioral and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Addenbrooke’s Hospital, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2010.09.040DOI Listing
February 2011

Impulsivity, compulsivity, and top-down cognitive control.

Neuron 2011 Feb;69(4):680-94

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge CB23EB, UK.

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http://dx.doi.org/10.1016/j.neuron.2011.01.020DOI Listing
February 2011

Trait-like impulsivity does not predict escalation of heroin self-administration in the rat.

Psychopharmacology (Berl) 2010 Dec 6;212(4):453-64. Epub 2010 Aug 6.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1007/s00213-010-1974-9DOI Listing
December 2010

Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour.

Hum Mol Genet 2009 Jun 20;18(12):2140-8. Epub 2009 Mar 20.

Behavioural Genetics Group, Department of Psychological Medicine and Neurology (School of Medicine) and School of Psychology, Cardiff University, Cardiff, UK.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddp137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685753PMC
June 2009

Dopamine receptors in the learning, memory and drug reward circuitry.

Semin Cell Dev Biol 2009 Jun 20;20(4):403-10. Epub 2009 Jan 20.

Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1016/j.semcdb.2009.01.002DOI Listing
June 2009

High impulsivity predicts relapse to cocaine-seeking after punishment-induced abstinence.

Biol Psychiatry 2009 May 1;65(10):851-6. Epub 2009 Feb 1.

Behavioral and Clinical Neuroscience Institute, University of Cambridge, Downing St, Cambridge CB2 3EB, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2008.12.008DOI Listing
May 2009

Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF.

Proc Natl Acad Sci U S A 2009 May 11;106(21):8754-9. Epub 2009 May 11.

Department of Clinical Neurosciences, Cambridge Centre for Brain Repair, University of Cambridge, Forvie Site, Robinson Way, Cambridge CB2 0PY, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0803955106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689002PMC
May 2009

Modelling human drug abuse and addiction with dedicated small animal positron emission tomography.

Neuropharmacology 2009 3;56 Suppl 1:9-17. Epub 2008 Jun 3.

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1016/j.neuropharm.2008.05.029DOI Listing
April 2009

Serotonin depletion impairs waiting but not stop-signal reaction time in rats: implications for theories of the role of 5-HT in behavioral inhibition.

Neuropsychopharmacology 2009 Apr 12;34(5):1311-21. Epub 2008 Nov 12.

Department of Experimental Psychology and the Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/npp.2008.202DOI Listing
April 2009

Remediation of attentional dysfunction in rats with lesions of the medial prefrontal cortex by intra-accumbens administration of the dopamine D(2/3) receptor antagonist sulpiride.

Psychopharmacology (Berl) 2009 Jan 5;202(1-3):307-13. Epub 2008 Nov 5.

Department of Experimental Psychology, University of Cambridge, Downing St, Cambridge CB23EB, UK.

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http://dx.doi.org/10.1007/s00213-008-1384-4DOI Listing
January 2009

Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction.

Philos Trans R Soc Lond B Biol Sci 2008 Oct;363(1507):3125-35

Department of Experimental Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge, UK.

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http://dx.doi.org/10.1098/rstb.2008.0089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607322PMC
October 2008

Opposing roles for 5-HT2A and 5-HT2C receptors in the nucleus accumbens on inhibitory response control in the 5-choice serial reaction time task.

Neuropsychopharmacology 2008 Sep 28;33(10):2398-406. Epub 2007 Nov 28.

Department of Experimental Psychology, Behavioral and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/sj.npp.1301636DOI Listing
September 2008

Neurobehavioral mechanisms of impulsivity: fronto-striatal systems and functional neurochemistry.

Pharmacol Biochem Behav 2008 Aug 27;90(2):250-60. Epub 2007 Dec 27.

Behavioral and Clinical Neuroscience Institute, University of Cambridge, Downing St, Cambridge, CB2 3EB, UK.

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http://dx.doi.org/10.1016/j.pbb.2007.12.021DOI Listing
August 2008

The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats.

Nat Protoc 2008 ;3(5):759-67

Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, UK.

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http://www.nature.com/articles/nprot.2008.41
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http://dx.doi.org/10.1038/nprot.2008.41DOI Listing
August 2008

High impulsivity predicts the switch to compulsive cocaine-taking.

Science 2008 Jun;320(5881):1352-5

Behavioural and Clinical Neuroscience Institute and Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK.

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http://dx.doi.org/10.1126/science.1158136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478705PMC
June 2008

Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease.

Brain 2008 Mar 17;131(Pt 3):630-41. Epub 2008 Jan 17.

Cambridge Center for Brain Repair and Department of Clinical Neurosciences, Forvie Site, Robinsons Way, Cambridge CB2 2PY, UK.

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http://dx.doi.org/10.1093/brain/awm340DOI Listing
March 2008

The orbital prefrontal cortex and drug addiction in laboratory animals and humans.

Ann N Y Acad Sci 2007 Dec 10;1121:576-97. Epub 2007 Sep 10.

Behavioural and Clinical Neuroscience and Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, UK.

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http://dx.doi.org/10.1196/annals.1401.022DOI Listing
December 2007