Publications by authors named "Jeffrey W Clark"

100Publications

Impact of Postoperative Complication and Completion of Multimodality Therapy on Survival in Patients Undergoing Gastrectomy for Advanced Gastric Cancer.

J Am Coll Surg 2020 Jun 6;230(6):912-924. Epub 2020 Feb 6.

Department of Surgery, Boston, MA; Massachusetts General Hospital, and Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.jamcollsurg.2019.12.038DOI Listing
June 2020

Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer.

Future Oncol 2020 Jan 28;16(1):4289-4301. Epub 2019 Nov 28.

Department of Medical Oncology & Therapeutics Research, The City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.2217/fon-2019-0653DOI Listing
January 2020

Clinical impact of PET/MR in treated colorectal cancer patients.

Eur J Nucl Med Mol Imaging 2019 Oct 29;46(11):2260-2269. Epub 2019 Jul 29.

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, White 270, Boston, MA, 02114, USA.

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http://link.springer.com/10.1007/s00259-019-04449-7
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http://dx.doi.org/10.1007/s00259-019-04449-7DOI Listing
October 2019

Case 32-2018: A 36-Year-Old Pregnant Woman with Newly Diagnosed Adenocarcinoma.

N Engl J Med 2018 Oct;379(16):1562-1570

From the Departments of Medicine (J.E.M., J.W.C.), Radiology (K.S.), Obstetrics and Gynecology (L.E.R.), and Pathology (K.M.B.), Massachusetts General Hospital, and the Departments of Medicine (J.E.M., J.W.C.), Radiology (K.S.), Obstetrics and Gynecology (L.E.R.), and Pathology (K.M.B.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1712230DOI Listing
October 2018

Recent progress in systemic treatment for lung cancer.

Curr Opin Pulm Med 2018 07;24(4):355-366

Harvard Medical School, Brigham and Women's Hospital, Dana Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MCP.0000000000000493DOI Listing
July 2018

Tivantinib for advanced hepatocellular carcinoma: is MET still a viable target?

Lancet Oncol 2018 05 3;19(5):591-592. Epub 2018 Apr 3.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(18)30249-3DOI Listing
May 2018

Phase II Study of Proton-Based Stereotactic Body Radiation Therapy for Liver Metastases: Importance of Tumor Genotype.

J Natl Cancer Inst 2017 09;109(9)

Department of Radiation Oncology, Department of Pathology, Division of Biostatistics, Department of Medicine, Division of Medical Oncology, Department of Medicine, Department of Radiology, and Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Harvard Radiation Oncology Program, Harvard Medical School, Boston, MA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1093/jnci/djx031DOI Listing
September 2017

Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.

J Clin Invest 2017 Aug 10;127(8):3039-3051. Epub 2017 Jul 10.

Edwin L. Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI93182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531423PMC
August 2017

Irradiation of anatomically defined pelvic subsites and acute hematologic toxicity in anal cancer patients undergoing chemoradiation.

Pract Radiat Oncol 2017 Sep - Oct;7(5):e291-e297. Epub 2017 Mar 23.

Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.prro.2017.03.008DOI Listing
May 2018

Limits to Precision Cancer Medicine.

N Engl J Med 2017 01;376(1):96

Massachusetts General Hospital, Boston, MA

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http://dx.doi.org/10.1056/NEJMc1613563DOI Listing
January 2017

Predictors of Early Mortality After Surgical Resection of Pancreatic Adenocarcinoma in the Era of Neoadjuvant Treatment.

Pancreas 2017 02;46(2):183-189

From the Departments of *Medical Oncology, †Surgery, ‡Biostatistics Center, and §Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/MPA.0000000000000731DOI Listing
February 2017

Acquired Resistance to Crizotinib in NSCLC with MET Exon 14 Skipping.

J Thorac Oncol 2016 08 22;11(8):1242-1245. Epub 2016 Jun 22.

Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jtho.2016.06.013DOI Listing
August 2016

A tunable delivery platform to provide local chemotherapy for pancreatic ductal adenocarcinoma.

Biomaterials 2016 07 31;93:71-82. Epub 2016 Mar 31.

Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2016.03.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849535PMC
July 2016

The impact of neoadjuvant therapy for gastroesophageal adenocarcinoma on postoperative morbidity and mortality.

J Surg Oncol 2016 Apr 21;113(5):560-4. Epub 2016 Jan 21.

Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/jso.24179DOI Listing
April 2016

Multi-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.

J Clin Oncol 2016 Feb 14;34(5):460-8. Epub 2015 Dec 14.

Theodore S. Hong, Jennifer Y. Wo, Beow Y. Yeap, Erin I. McDonnell, Lawrence S. Blaszkowsky, Eunice L. Kwak, Jill N. Allen, Jeffrey W. Clark, Lipika Goyal, Janet E. Murphy, John A. Wolfgang, Lorraine C. Drapek, Ronald S. Arellano, John T. Mullen, Sam S. Yoon, Kenneth K. Tanabe, Cristina R. Ferrone, David P. Ryan, Thomas F. DeLaney, and Andrew X. Zhu, Massachusetts General Hospital, Harvard Medical School; Harvey J. Mamon, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; Edgar Ben-Josef, University of Pennsylvania Hospital, Philadelphia, PA; and Milind M. Javle and Christopher H. Crane, University of Texas MD Anderson Cancer Center, Houston, TX.

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http://jco.ascopubs.org/content/early/2015/12/11/JCO.2015.64
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http://jco.ascopubs.org/content/suppl/2015/12/14/JCO.2015.64
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.64.2710
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http://dx.doi.org/10.1200/JCO.2015.64.2710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872014PMC
February 2016

NCCN Oncology Research Program's Investigator Steering Committee and NCCN Best Practices Committee Molecular Profiling Surveys.

J Natl Compr Canc Netw 2015 Nov;13(11):1337-46

From UC San Diego Moores Cancer Center, San Diego, California; Stanford Cancer Institute, Stanford, California; Fox Chase Cancer Center, Philadelphia, Pennsylvania; Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute, Columbus, Ohio; Massachusetts General Hospital Cancer Center, Boston, Massachusetts; Washington University, St. Louis, Missouri; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland; City of Hope Comprehensive Cancer Center, Los Angeles, California; The West Clinic, Memphis, Tennessee; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California; Johns Hopkins University School of Medicine, Baltimore, Maryland; and Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance.

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http://dx.doi.org/10.6004/jnccn.2015.0163DOI Listing
November 2015

Familial Gastric Cancers.

Oncologist 2015 Dec 30;20(12):1365-77. Epub 2015 Sep 30.

Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA

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http://dx.doi.org/10.1634/theoncologist.2015-0205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679084PMC
December 2015

Adjuvant Therapy Completion Rates in Patients with Gastric Cancer Undergoing Perioperative Chemotherapy Versus a Surgery-First Approach.

J Gastrointest Surg 2016 Jan 22;20(1):172-9; discussion 179. Epub 2015 Sep 22.

Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Yawkey 7B, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s11605-015-2954-5DOI Listing
January 2016

Crizotinib in ROS1-rearranged non-small-cell lung cancer.

N Engl J Med 2014 Nov 27;371(21):1963-71. Epub 2014 Sep 27.

From the Massachusetts General Hospital Cancer Center (A.T.S., L.P.L., Z.Z., J.W.C., A.J.I.), Dana-Farber Cancer Institute (G.I.S.), and Beth Israel Deaconess Medical Center (D.B.C.) - all in Boston; University of California at Irvine, Irvine (S.-H.I.O.), and Pfizer Oncology, La Jolla (W.T., S.M.S., L.M.T., J.G.C., K.D.W.) - both in California; Seoul National University Hospital, Seoul, South Korea (Y.-J.B.); University of Colorado, Aurora (D.R.C., M.V.-G., R.C.D.); Peter MacCallum Cancer Centre, Melbourne, VIC, Australia (B.J.S.); University of Chicago, Chicago (R.S.); Memorial Sloan Kettering Cancer Center, New York (G.J.R.); Karolinska Institutet, Stockholm (Z.Z.); and Rho, Chapel Hill, NC (P.S.).

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http://dx.doi.org/10.1056/NEJMoa1406766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264527PMC
November 2014

Evaluation of statistical designs in phase I expansion cohorts: the Dana-Farber/Harvard Cancer Center experience.

J Natl Cancer Inst 2014 Jul 24;106(7). Epub 2014 Jun 24.

Affiliations of authors: Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA (SED); Department of Medical Oncology and Department of Medicine, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA (GIS, BEJ); Department of Hematology and Oncology (JWC) and Department of Medicine (JWC), Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1093/jnci/dju163DOI Listing
July 2014

Crizotinib as salvage and maintenance with allogeneic stem cell transplantation for refractory anaplastic large cell lymphoma.

J Natl Compr Canc Netw 2014 Mar;12(3):323-6; quiz 326

From aDana-Farber Cancer Institute, Harvard Medical School and bBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; cUniversity of Rochester Medical Center, University of Rochester, Rochester, New York; and dMassachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.6004/jnccn.2014.0034DOI Listing
March 2014

Extended cycle combined oral contraceptives and prophylactic frovatriptan during the hormone-free interval in women with menstrual-related migraines.

J Womens Health (Larchmt) 2014 Apr 22;23(4):310-7. Epub 2014 Jan 22.

1 Department of Obstetrics and Gynecology, Texas A&M Health Science Center College of Medicine , Temple, Texas.

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http://dx.doi.org/10.1089/jwh.2013.4485DOI Listing
April 2014

Targeted inhibition in tumors with ALK dependency.

Lung Cancer (Auckl) 2013 9;4:1-8. Epub 2013 Jan 9.

Massachusetts General Hospital Cancer Center, Boston, MA, USA.

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http://dx.doi.org/10.2147/LCTT.S16313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217435PMC
January 2013

Drug interactions: the importance of looking inside cancer cells.

Authors:
Jeffrey W Clark

Cancer Discov 2012 Mar;2(3):208-10

Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0040DOI Listing
March 2012

Cancers of the colon and rectum: identical or fraternal twins?

Cancer Discov 2012 Feb;2(2):117-21

Department of Radiation Oncology, Department of Medicine, and Molecular Pathology Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0315DOI Listing
February 2012

Field evaluation of a wicking assay for the rapid detection of Rift Valley fever viral antigens in mosquitoes.

J Am Mosq Control Assoc 2011 Dec;27(4):370-5

Division of Entomology, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.

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http://dx.doi.org/10.2987/11-6176.1DOI Listing
December 2011

Evaluation of ULV applications against Old World sand fly (Diptera: Psychodidae) species in equatorial Kenya.

J Med Entomol 2011 Nov;48(6):1145-59

United States Department of Agriculture, Agricultural Research Service, Center for Medical, Agricultural, and Veterinary Entomology, 1600 SW 23rd Dr., Gainesville, FL 32608, USA.

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http://www.afpmb.org/sites/default/files/pubs/dwfp/publicati
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http://dx.doi.org/10.1603/me11025DOI Listing
November 2011

Case records of the Massachusetts General Hospital: Case 3-2011: a 58-year-old woman with a mass in the liver.

N Engl J Med 2011 Jan;364(4):362-70

Division of Surgical Oncology,the Department of Surgery, Massachusetts GeneralHospital, Boston, USA.

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http://dx.doi.org/10.1056/NEJMcpc1000965DOI Listing
January 2011

Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer.

J Thorac Oncol 2010 Dec;5(12):2044-6

Division of Hematology-Oncology, Department of Medicine, Chao Family Comprehensive Cancer Center, University of Irvine Medical Center, Orange, California 92868-3298, USA.

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http://dx.doi.org/10.1097/JTO.0b013e318200f9ffDOI Listing
December 2010