Publications by authors named "Jeffrey Trent"

100Publications

Stool Microbiome Profiling of Patients with Metastatic Renal Cell Carcinoma Receiving Anti-PD-1 Immune Checkpoint Inhibitors.

Eur Urol 2020 Oct 19;78(4):498-502. Epub 2020 Aug 19.

Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eururo.2020.07.011DOI Listing
October 2020

Strategies for Testing Intervention Matching Schemes in Cancer.

Clin Pharmacol Ther 2020 Jun 14. Epub 2020 Jun 14.

The Translational Genomics Research Institute (TGen), Phoenix, Arizona, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpt.1947DOI Listing
June 2020

Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility.

Int J Cancer 2019 11 18;145(9):2372-2382. Epub 2019 Mar 18.

State Key Laboratory of Genetic Engineering, Zhongshan Hospital, Fudan University, and School of Life Sciences, Fudan University, Shanghai, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.32179DOI Listing
November 2019

Molecular Guided Therapy Provides Sustained Clinical Response in Refractory Choroid Plexus Carcinoma.

Front Pharmacol 2017 25;8:652. Epub 2017 Sep 25.

Pediatric Oncology Translational Research Program, Helen DeVos Children's Hospital at Spectrum HealthGrand Rapids, MI, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphar.2017.00652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622196PMC
September 2017

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

J Pathol 2017 07 2;242(3):371-383. Epub 2017 Jun 2.

Department of Pathology and Laboratory Medicine, University of British Columbia and Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC, Canada.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/path.4912
Publisher Site
http://dx.doi.org/10.1002/path.4912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857704PMC
July 2017

Promoter Mutations Ablate GABP Transcription Factor Binding in Melanoma.

Cancer Res 2017 04 20;77(7):1649-1661. Epub 2017 Jan 20.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-16-0919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711603PMC
April 2017

A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters.

J Am Chem Soc 2016 Oct 5;138(41):13673-13692. Epub 2016 Oct 5.

University of Arizona , College of Pharmacy, 1703 East Mabel Street, Tucson, Arizona 85721, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jacs.6b07598DOI Listing
October 2016

The influence of clinical and genetic factors on patient outcome in small cell carcinoma of the ovary, hypercalcemic type.

Gynecol Oncol 2016 06 19;141(3):454-460. Epub 2016 Mar 19.

Department of Human Genetics, McGill University, Montreal, QC, Canada; Lady Davis Institute and Segal Cancer Center, Jewish General Hospital, Montreal, QC, Canada; Department of Medical Genetics and Cancer Research Program, Research Institute, McGill University Health Centre, Montreal, QC, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ygyno.2016.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876126PMC
June 2016

Toward precision medicine in glioblastoma: the promise and the challenges.

Neuro Oncol 2015 Aug 1;17(8):1051-63. Epub 2015 May 1.

University of California San Francisco, San Francisco, California (M.D.P, J.J.P., A.M.M., S.M.C.); Translational Genomics Research Institute, Phoenix, Arizona (S.A.B., N.L.T., W.D.T., J.A.K., M.E.B., D.W.C., J.D.C., J.M.T.); Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (K.L.L., P.Y.W.); University of Texas Health Science Center, San Antonio, Texas (J.G.K.); Memorial Sloan-Kettering Cancer Center, New York, New York (I.K.M.); The University of Texas M.D. Anderson Cancer Center, Houston, Texas (J.F.d.G.); University of Utah Huntsman Cancer Institute, Salt Lake City, Utah (H.C.); University of California Los Angeles, Los Angeles, California (T.F.C.); Iowa Spine and Brain Institute, Waterloo, Iowa (T.C.R.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/nov031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490873PMC
August 2015

Assessing Combinational Drug Efficacy in Cancer Cells by Using Image-based Dynamic Response Analysis.

Cancer Inform 2015 9;14(Suppl 5):33-43. Epub 2016 Mar 9.

Center for Bioinformatics and Genomic Systems Engineering, Texas A&M Engineering Experiment Station, Texas A&M University, College Station, TX, USA.; Translational Genomics Research Institute, Phoenix, AZ, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4137/CIN.S30799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786100PMC
March 2016

Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma.

J Natl Cancer Inst 2015 Feb 13;107(2). Epub 2014 Dec 13.

Affiliations of authors: QIMR Berghofer Medical Research Institute, Brisbane, Australia (LGA, ALP, MG, PJ, JMP, JS, VB, SW, KDR, MSS, GWM, NGM, NKH); Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK (CDRE, TMK, DJA); Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark (KW, AMG); Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK (MH, HSn, DTB, JANB); Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD (JC, KMB); Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología del Principado de Asturias (IUOPA) Universidad de Oviedo, Oviedo, Spain (VQ, AJR, CLO); Cancer Genomics Research Laboratory, NCI Frederick, SAIC-Frederick Inc., Frederick MD (XZ, KJ); Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands (RvD, NAG); Department of Clinical Sciences Lund, Division of Oncology and Pathology, Lund University, Lund, Sweden (HO, CI, ÅB, GJ); Translational Genomics Institute, Phoenix, AZ (JMT); University of Sydney at Westmead Millennium Institute, Westmead, Sydney, NSW, Australia (EAH, HSc, GJM); Melanoma Institute Australia, North Sydney, NSW, Australia (EAH, HSc, GJM).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/dju408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334787PMC
February 2015

8q24 risk alleles and prostate cancer in African-Barbadian men.

Prostate 2014 Dec 22;74(16):1579-88. Epub 2014 Sep 22.

Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.22871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322001PMC
December 2014

A BAP1 mutation in a Danish family predisposes to uveal melanoma and other cancers.

PLoS One 2013 19;8(8):e72144. Epub 2013 Aug 19.

Oncogenomics Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia ; University of Queensland, Brisbane, Queensland, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072144PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747051PMC
April 2014

The BioIntelligence Framework: a new computational platform for biomedical knowledge computing.

J Am Med Inform Assoc 2013 Jan 2;20(1):128-33. Epub 2012 Aug 2.

The Translational Genomics Research Institute (TGen), Center for BioIntelligence, Phoenix, AZ 85004, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/amiajnl-2011-000646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555311PMC
January 2013

Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.

Hum Mol Genet 2012 Jun 24;21(11):2610-7. Epub 2012 Feb 24.

Fudan Institute of Urology, Huashan Hospital, School of Life Sciences, Fudan University, Shanghai, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/dds062DOI Listing
June 2012

High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells.

Mol Cancer Res 2011 Jun 2;9(6):724-32. Epub 2011 May 2.

Clinical Translational Research Division, Translational Genomics Research Institute, Scottsdale, AZ 85259, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-10-0436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137903PMC
June 2011

Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis.

Cancer Res 2011 Apr 2;71(8):3162-72. Epub 2011 Feb 2.

State Key Laboratory of Oncology in South China, Departments of Pathology and Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-10-3557DOI Listing
April 2011

Contribution of HPC1 (RNASEL) and HPCX variants to prostate cancer in a founder population.

Prostate 2010 Nov;70(15):1716-27

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.21207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404133PMC
November 2010

Conditioning-based modeling of contextual genomic regulation.

IEEE/ACM Trans Comput Biol Bioinform 2009 Apr-Jun;6(2):310-20

Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843-3128, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TCBB.2007.70247DOI Listing
August 2009

Functional evidence implicating S100P in prostate cancer progression.

Int J Cancer 2008 Jul;123(2):330-339

Pharmaceutical Genomics Division, The Translational Genomics Research Institute, Scottsdale, AZ.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.23447DOI Listing
July 2008

Adrenocortical carcinoma survival rates correlated to genomic copy number variants.

Mol Cancer Ther 2008 Feb;7(2):425-31

Genetic Basis of Human Disease Division, Translational Genomics Research Institute, 445 North 5th Street, Phoenix, AZ 85004, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-07-0267DOI Listing
February 2008

Cancer. The gene topography of cancer.

Science 2007 Nov;318(5853):1079-80

Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1151428DOI Listing
November 2007

Optimization of oligonucleotide microarray fabricated by spotting 65-mer.

Anal Biochem 2007 Sep 8;368(1):61-9. Epub 2007 Jun 8.

Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ab.2007.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697255PMC
September 2007

Performance characteristics of 65-mer oligonucleotide microarrays.

Anal Biochem 2007 Sep 13;368(1):70-8. Epub 2007 May 13.

Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ab.2007.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697254PMC
September 2007

Genome-wide linkage scan for prostate cancer susceptibility genes in men with aggressive disease: significant evidence for linkage at chromosome 15q12.

Hum Genet 2006 May 1;119(4):400-7. Epub 2006 Mar 1.

Department of Genetics, University of North Carolina, 4300D MBRB, CB# 7264, 103 Mason Farm Road, Chapel Hill, NC 27599-7264, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00439-006-0149-6DOI Listing
May 2006

Notch and NOXA-related pathways in melanoma cells.

J Investig Dermatol Symp Proc 2005 Nov;10(2):95-104

Department of Pathology, Oncology Institute, Cardinal Bernardin Cancer Center, Loyola University, Chicago, Illinois 60153-5385, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1087-0024.2005.200404.xDOI Listing
November 2005

Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment.

Cancer Res 2005 Nov;65(22):10164-9

Children's Memorial Research Center and Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, IL 60614, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-05-2497DOI Listing
November 2005

The interaction of four genes in the inflammation pathway significantly predicts prostate cancer risk.

Cancer Epidemiol Biomarkers Prev 2005 Nov;14(11 Pt 1):2563-8

Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1055-9965.EPI-05-0356DOI Listing
November 2005

Oncogenomics 2005 meeting report: dissecting cancer through genome research.

Cancer Res 2005 Oct;65(19):8587-90

Translational Genomics Research Institute, Phoenix, Arizona 85004, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-05-2659DOI Listing
October 2005

Stress-specific signatures: expression profiling of p53 wild-type and -null human cells.

Oncogene 2005 Jun;24(28):4572-9

Gene Response Section, Center for Cancer Research, NCI, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.onc.1208653DOI Listing
June 2005

Genome-wide screen for prostate cancer susceptibility genes in men with clinically significant disease.

Prostate 2005 Sep;64(4):356-61

Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.20249DOI Listing
September 2005

Evidence for a general cancer susceptibility locus at 3p24 in families with hereditary prostate cancer.

Cancer Lett 2005 Mar;219(2):177-82

Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2004.10.005DOI Listing
March 2005

GeneLink: a database to facilitate genetic studies of complex traits.

BMC Genomics 2004 Oct 18;5:81. Epub 2004 Oct 18.

Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892-8000, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-5-81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC526767PMC
October 2004

Which is better for cDNA-microarray-based classification: ratios or direct intensities.

Bioinformatics 2004 Nov 28;20(16):2513-20. Epub 2004 Sep 28.

Department of Electrical Engineering, Texas A&M University, College Station, TX 78041, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/bth272DOI Listing
November 2004