Jeffrey S Smith

Jeffrey S Smith

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Jeffrey S Smith

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Early postoperative results of Descemet's stripping endothelial keratoplasty in six dogs with corneal endothelial dystrophy.

Vet Ophthalmol 2019 Nov 21;22(6):879-890. Epub 2019 Mar 21.

Eye Clinic for Animals, Crows Nest, New South Wales, Australia.

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http://dx.doi.org/10.1111/vop.12666DOI Listing
November 2019

Tandem Mass Tag Labeling Facilitates Reversed-Phase Liquid Chromatography-Mass Spectrometry Analysis of Hydrophilic Phosphopeptides.

Anal Chem 2019 09 28;91(18):11606-11613. Epub 2019 Aug 28.

Biological Sciences Division , Pacific Northwest National Laboratory , Richland , Washington 99354 , United States.

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http://dx.doi.org/10.1021/acs.analchem.9b01814DOI Listing
September 2019

Pathogen Evasion of Chemokine Response Through Suppression of CXCL10.

Front Cell Infect Microbiol 2019 7;9:280. Epub 2019 Aug 7.

Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, United States.

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http://dx.doi.org/10.3389/fcimb.2019.00280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693555PMC
August 2019

A Sir2-regulated locus control region in the recombination enhancer of Saccharomyces cerevisiae specifies chromosome III structure.

PLoS Genet 2019 08 28;15(8):e1008339. Epub 2019 Aug 28.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736312PMC
August 2019

T Cells Expressing the Chemokine Receptor CXCR3 Localize to Positive Patch Test Reaction Sites.

Dermatitis 2018 Jul/Aug;29(4):228-229

Department of Biochemistry, Duke University, Durham, NC Department of Dermatology, Duke University, Durham, NC Department of Dermatology, Duke University, Durham, NC Department of Dermatology, Duke University, Durham, NC

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http://dx.doi.org/10.1097/DER.0000000000000367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053320PMC
June 2019

Antibody responses to crucial functional epitopes as a novel approach to assess immunogenicity of vaccine adjuvants.

Vaccine 2019 06 29;37(29):3770-3778. Epub 2019 May 29.

Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2019.05.068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579625PMC
June 2019

Depletion of Limiting rDNA Structural Complexes Triggers Chromosomal Instability and Replicative Aging of .

Genetics 2019 05 6;212(1):75-91. Epub 2019 Mar 6.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia 22908

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http://dx.doi.org/10.1534/genetics.119.302047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499517PMC
May 2019

Biased signalling: from simple switches to allosteric microprocessors.

Nat Rev Drug Discov 2018 04 5;17(4):243-260. Epub 2018 Jan 5.

Department of Biochemistry, Duke University Medical Center.

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http://www.nature.com/doifinder/10.1038/nrd.2017.229
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http://dx.doi.org/10.1038/nrd.2017.229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936084PMC
April 2018

Spontaneous mutations in and suppress the short chronological lifespan of budding yeast lacking SNF1/AMPK.

Microb Cell 2018 Feb 19;5(5):233-248. Epub 2018 Feb 19.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908.

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http://microbialcell.com/researcharticles/spontaneous-mutati
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http://dx.doi.org/10.15698/mic2018.05.630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961917PMC
February 2018

C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways.

Mol Pharmacol 2017 08 30;92(2):136-150. Epub 2017 May 30.

Department of Biochemistry (J.S.S., P.A., N.K.D., S.R.), Department of Pharmacology and Cancer Biology (T.F.P.), and Department of Medicine (J.-H.W., N.J.F., S.R.), Duke University Medical Center, Durham, NC 27710; Department of Pharmaceutical Sciences, Tohoku University, Japan (A.I.); and Japan Science and Technology Agency, Precursory Research for Embryonic Science and Technology (PRESTO), Japan (A.I.)

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http://dx.doi.org/10.1124/mol.117.108522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508197PMC
August 2017

Caloric Restriction Extends Yeast Chronological Life Span by Optimizing the Snf1 (AMPK) Signaling Pathway.

Mol Cell Biol 2017 07 15;37(13). Epub 2017 Jun 15.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia, USA

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http://mcb.asm.org/lookup/doi/10.1128/MCB.00562-16
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http://dx.doi.org/10.1128/MCB.00562-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472825PMC
July 2017

Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus.

Neural Plast 2016 18;2016:3928726. Epub 2016 Feb 18.

The Brain Research Laboratory, Saginaw Valley State University, University Center, MI 48710, USA.

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http://www.hindawi.com/journals/np/2016/3928726/
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http://dx.doi.org/10.1155/2016/3928726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775817PMC
December 2016

The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.

Genetics 2016 Aug;203(4):1563-99

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia 22908

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http://dx.doi.org/10.1534/genetics.112.145243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981263PMC
August 2016

RNA Polymerase I and Fob1 contributions to transcriptional silencing at the yeast rDNA locus.

Nucleic Acids Res 2016 07 8;44(13):6173-84. Epub 2016 Apr 8.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkw212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291248PMC
July 2016

The β-Arrestins: Multifunctional Regulators of G Protein-coupled Receptors.

J Biol Chem 2016 Apr 16;291(17):8969-77. Epub 2016 Mar 16.

From the Departments of Biochemistry and Medicine, Duke University Medical Center, Durham, North Carolina 27710

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http://dx.doi.org/10.1074/jbc.R115.713313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861465PMC
April 2016

Post-operative environmental enrichment improves spatial and motor deficits but may not ameliorate anxiety- or depression-like symptoms in rats following traumatic brain injury.

Restor Neurol Neurosci 2014 ;32(5):701-16

The Brain Research Laboratory, Saginaw Valley State University, University Center, MI, USA.

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http://dx.doi.org/10.3233/RNN-140414DOI Listing
July 2015

Combining Enriched Environment, Progesterone, and Embryonic Neural Stem Cell Therapy Improves Recovery after Brain Injury.

J Neurotrauma 2015 Jul 18;32(14):1117-29. Epub 2015 Mar 18.

The Brain Research Laboratory, Saginaw Valley State University , University Center, Michigan.

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http://dx.doi.org/10.1089/neu.2014.3618DOI Listing
July 2015

A user's guide to the ribosomal DNA in Saccharomyces cerevisiae.

Methods Mol Biol 2014 ;1205:303-28

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.

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http://dx.doi.org/10.1007/978-1-4939-1363-3_18DOI Listing
May 2015

Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populations.

Aging (Albany NY) 2015 Mar;7(3):177-94

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394729PMC
http://dx.doi.org/10.18632/aging.100729DOI Listing
March 2015

Pre and post-injury environmental enrichment effects functional recovery following medial frontal cortical contusion injury in rats.

Behav Brain Res 2014 Dec 6;275:201-11. Epub 2014 Sep 6.

The Brain Research Laboratory, Saginaw Valley State University, 7400 Bay Road, University Center, Michigan, 48710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2014.08.056DOI Listing
December 2014

Characterization of individual mouse cerebrospinal fluid proteomes.

Proteomics 2014 May 20;14(9):1102-6. Epub 2014 Mar 20.

Department of Pharmacology, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1002/pmic.201300241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044923PMC
May 2014

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane.

Mol Metab 2014 Apr 28;3(2):114-23. Epub 2013 Nov 28.

Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA ; Department of Medicine, University of Virginia, Charlottesville, VA 22908, USA ; Department of Cardiovascular Research Center, University of Virginia, Charlottesville, VA 22908, USA ; Emily Couric Clinical Cancer Center, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/j.molmet.2013.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953706PMC
April 2014

Mechanism of macromolecular structure evolution in self-assembled lipid nanoparticles for siRNA delivery.

Langmuir 2014 Apr 9;30(16):4613-22. Epub 2014 Apr 9.

Department of Pharmaceutical Sciences and ‡Department of RNA Therapeutics, Merck Research Laboratories, Merck and Co., Inc. , West Point, Pennsylvania 19486, United States.

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http://pubs.acs.org/doi/10.1021/la500630h
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http://dx.doi.org/10.1021/la500630hDOI Listing
April 2014

Yeast sirtuins and the regulation of aging.

FEMS Yeast Res 2014 Feb 14;14(1):73-88. Epub 2013 Nov 14.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.

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http://dx.doi.org/10.1111/1567-1364.12115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365911PMC
February 2014

PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling.

J Mol Cell Cardiol 2014 Jan 10;66:83-93. Epub 2013 Nov 10.

Department of Biomedical Engineering, Robert M. Berne Cardiovascular Research Center, University of Virginia, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222828130032
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http://dx.doi.org/10.1016/j.yjmcc.2013.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927644PMC
January 2014

Rpd3- and spt16-mediated nucleosome assembly and transcriptional regulation on yeast ribosomal DNA genes.

Mol Cell Biol 2013 Jul 20;33(14):2748-59. Epub 2013 May 20.

Department of Biochemistry and Molecular Genetics, University of Virginia, School of Medicine, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1128/MCB.00112-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700123PMC
July 2013

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement.

Nat Med 2013 Apr 24;19(4):452-7. Epub 2013 Mar 24.

Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/nm.3107DOI Listing
April 2013

Undergraduate neuroscience faculty: results from a survey of faculty for undergraduate neuroscience members.

J Undergrad Neurosci Educ 2010 15;8(2):A101-7. Epub 2010 Mar 15.

Biology Department, Ithaca College, Ithaca NY 14850;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592718PMC
March 2013

Successive bilateral frontal controlled cortical impact injuries show behavioral savings.

Behav Brain Res 2013 Mar 28;240:153-9. Epub 2012 Nov 28.

Restorative Neuroscience Laboratory, Center for Integrated Research in Cognitive and Neural Sciences, Department of Psychology, Southern Illinois University, Carbondale, IL, USA.

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http://dx.doi.org/10.1016/j.bbr.2012.11.029DOI Listing
March 2013

The effects of acute voluntary wheel running on recovery of function following medial frontal cortical contusions in rats.

Restor Neurol Neurosci 2012 ;30(4):325-33

Neuroscience Graduate Program, Central Michigan University, MI, USA.

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http://www.medra.org/servlet/aliasResolver?alias=iospress&am
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http://dx.doi.org/10.3233/RNN-2012-120232DOI Listing
November 2012

Place attachment among retirees in Greensburg, Kansas.

Geogr Rev 2011 ;101(4):536-55

Kansas State University, Manhattan.

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http://dx.doi.org/10.1111/j.1931-0846.2011.00116.xDOI Listing
October 2012

Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive.

Nature 2012 Oct 19;490(7420):402-6. Epub 2012 Sep 19.

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1038/nature11436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475726PMC
October 2012

Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration.

J Biol Chem 2012 Jun 26;287(25):20957-66. Epub 2012 Apr 26.

Department of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1074/jbc.M112.367524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375519PMC
June 2012

The role of endosomal escape and mitogen-activated protein kinases in adenoviral activation of the innate immune response.

PLoS One 2011 27;6(10):e26755. Epub 2011 Oct 27.

Division of Cellular and Gene Therapies, Food and Drug Administration Center for Biologics Evaluation and Research, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026755PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203151PMC
March 2012

Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator.

Eur J Pharmacol 2011 Jun 16;659(2-3):146-54. Epub 2011 Feb 16.

Neuroscience Department, AstraZeneca Pharmaceuticals, Wilmington, DE, United States.

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http://dx.doi.org/10.1016/j.ejphar.2011.02.003DOI Listing
June 2011

Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes.

Mol Cell Biol 2011 Feb 22;31(3):482-94. Epub 2010 Nov 22.

Department of Microbiology, Box 800734, University of Virginia Health System, Charlottesville, VA 22908-0734, USA.

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http://dx.doi.org/10.1128/MCB.00589-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028620PMC
February 2011

Thiamine biosynthesis in Saccharomyces cerevisiae is regulated by the NAD+-dependent histone deacetylase Hst1.

Mol Cell Biol 2010 Jul 3;30(13):3329-41. Epub 2010 May 3.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, School of Medicine, Jordan Hall, Box 800733, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1128/MCB.01590-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897578PMC
July 2010

A microarray-based genetic screen for yeast chronological aging factors.

PLoS Genet 2010 Apr 22;6(4):e1000921. Epub 2010 Apr 22.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, School of Medicine, Charlottesville, Virginia, United States of America.

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http://dx.plos.org/10.1371/journal.pgen.1000921
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http://dx.doi.org/10.1371/journal.pgen.1000921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858703PMC
April 2010

Induction of shock after intravenous injection of adenovirus vectors: a critical role for platelet-activating factor.

Mol Ther 2010 Mar 1;18(3):609-16. Epub 2009 Dec 1.

Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/mt.2009.279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839431PMC
March 2010

Calorie restriction effects on silencing and recombination at the yeast rDNA.

Aging Cell 2009 Dec 2;8(6):633-42. Epub 2009 Sep 2.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, School of Medicine, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1111/j.1474-9726.2009.00516.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163344PMC
December 2009

Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo.

J Virol 2009 Jun 25;83(11):5648-58. Epub 2009 Mar 25.

Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1128/JVI.00082-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681959PMC
June 2009

Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae.

Genetics 2009 May 6;182(1):105-19. Epub 2009 Mar 6.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1534/genetics.108.100313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674809PMC
May 2009

Limiting the extent of the RDN1 heterochromatin domain by a silencing barrier and Sir2 protein levels in Saccharomyces cerevisiae.

Mol Cell Biol 2009 May 16;29(10):2889-98. Epub 2009 Mar 16.

Department of Biochemistry, Indian Institute of Science, C. V. Raman Ave., Bangalore KA 560012, India.

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http://dx.doi.org/10.1128/MCB.00728-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682026PMC
May 2009

Molecular characterization of nitrogen-containing organic compounds in biomass burning aerosols using high-resolution mass spectrometry.

Environ Sci Technol 2009 May;43(10):3764-71

William R. Wiley Environmental Molecular Sciences Laboratory and Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, MSIN K8-88, Richland, Washington 99352, USA.

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http://dx.doi.org/10.1021/es803456nDOI Listing
May 2009

Molecular characterization of biomass burning aerosols using high-resolution mass spectrometry.

Anal Chem 2009 Feb;81(4):1512-21

Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, MSIN K8-88, Richland, Washington 99352, USA.

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http://dx.doi.org/10.1021/ac8020664DOI Listing
February 2009

Clearance of adenovirus by Kupffer cells is mediated by scavenger receptors, natural antibodies, and complement.

J Virol 2008 Dec 24;82(23):11705-13. Epub 2008 Sep 24.

Division of Cellular and Gene Therapies, FDA/CBER, 8800 Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1128/JVI.01320-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583672PMC
December 2008

Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30.

Mol Cell Biol 2008 Nov 2;28(21):6709-19. Epub 2008 Sep 2.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, School of Medicine, Charlottesville, VA 22908, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.00703-08
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http://dx.doi.org/10.1128/MCB.00703-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573240PMC
November 2008

Pnc1p-mediated nicotinamide clearance modifies the epigenetic properties of rDNA silencing in Saccharomyces cerevisiae.

Genetics 2008 Oct 9;180(2):797-810. Epub 2008 Sep 9.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1534/genetics.108.091090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567381PMC
October 2008

Interaction of systemically delivered adenovirus vectors with Kupffer cells in mouse liver.

Hum Gene Ther 2008 May;19(5):547-54

Division of Cellular and Gene Therapies, Food and Drug Administration Center for Biologics Evaluation and Research, Bethesda, MD 20892, USA.

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http://www.liebertpub.com/doi/10.1089/hum.2008.004
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http://dx.doi.org/10.1089/hum.2008.004DOI Listing
May 2008

A quantitative assay for measuring clearance of adenovirus vectors by Kupffer cells.

J Virol Methods 2008 Jan 11;147(1):54-60. Epub 2007 Sep 11.

Division of Cellular and Gene Therapies, Food and Drug Administration, Center for Biologics Evaluation and Research, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.jviromet.2007.08.009DOI Listing
January 2008

Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins.

Aging Cell 2007 Oct 15;6(5):649-62. Epub 2007 Aug 15.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, School of Medicine, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1111/j.1474-9726.2007.00326.xDOI Listing
October 2007

Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+.

Cell 2007 May;129(3):473-84

Departments of Genetics and Biochemistry and the Norris Cotton Cancer Center, Dartmouth Medical School, Rubin 733-HB7937, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1016/j.cell.2007.03.024DOI Listing
May 2007

Regulation of rRNA synthesis by TATA-binding protein-associated factor Mot1.

Mol Cell Biol 2007 Apr 12;27(8):2886-96. Epub 2007 Feb 12.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, 1300 Jefferson Park Avenue, Charlottesville, Virginia 22908-0733, USA.

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http://mcb.asm.org/content/27/8/2886.full.pdf
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http://mcb.asm.org/cgi/doi/10.1128/MCB.00054-07
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http://dx.doi.org/10.1128/MCB.00054-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899949PMC
April 2007

Rapid Kupffer cell death after intravenous injection of adenovirus vectors.

Mol Ther 2006 Jan 28;13(1):108-17. Epub 2005 Sep 28.

Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152500160501559
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http://dx.doi.org/10.1016/j.ymthe.2005.08.007DOI Listing
January 2006

Diversity in the Sir2 family of protein deacetylases.

J Leukoc Biol 2004 Jun 23;75(6):939-50. Epub 2004 Jan 23.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Jordan Hall, Box 800733, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1189/jlb.0903424DOI Listing
June 2004

Sir Antagonist 1 (San1) is a ubiquitin ligase.

J Biol Chem 2004 Jun 12;279(26):26830-8. Epub 2004 Apr 12.

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, Virginia 22908-0733, USA.

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http://dx.doi.org/10.1074/jbc.M400894200DOI Listing
June 2004

Severe pulmonary pathology after intravenous administration of vectors in cirrhotic rats.

Mol Ther 2004 Jun;9(6):932-41

Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ymthe.2004.03.010DOI Listing
June 2004

Bilateral phacofragmentation in a New Zealand fur seal (Arctocephalus forsteri).

J Zoo Wildl Med 2004 Mar;35(1):110-2

Veterinary and Quarantine Centre, Taronga Zoo, P.O. Box 20, Mosman, New South Wales 2088, Australia.

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http://dx.doi.org/10.1638/02-037DOI Listing
March 2004

Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity.

Mol Cell Biol 2004 Feb;24(3):1301-12

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, Virginia 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC321434PMC
http://dx.doi.org/10.1128/mcb.24.3.1301-1312.2004DOI Listing
February 2004

RNA polymerase I propagates unidirectional spreading of rDNA silent chromatin.

Cell 2002 Dec;111(7):1003-14

Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/s0092-8674(02)01193-5DOI Listing
December 2002

RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase.

EMBO J 2002 Sep;21(18):4959-68

Department of Biochemistry and Molecular Genetics and Department of Microbiology, University of Virginia Health System, Charlottesville, VA 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126294PMC
http://dx.doi.org/10.1093/emboj/cdf498DOI Listing
September 2002

SIR2 family of NAD(+)-dependent protein deacetylases.

Methods Enzymol 2002 ;353:282-300

Department of Biochemistry and Molecular Genetics, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)53056-1DOI Listing
August 2002

Telomeric and rDNA silencing in Saccharomyces cerevisiae are dependent on a nuclear NAD(+) salvage pathway.

Genetics 2002 Mar;160(3):877-89

Department of Biochemistry and Molecular Genetics, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462005PMC
March 2002