Jeffrey R Mann

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma.

Authors:

Hsiao P J Voon Maheshi Udugama Wendi Lin Linda Hii Ruby H P Law David L Steer Partha P Das Jeffrey R Mann Lee H Wong

Nat Commun 2018 08 7;9(1):3142. Epub 2018 Aug 7.

Department of Biochemistry and Molecular Biology, Cancer Program, Biomedicine Discovery Institute, Monash University, Wellington Road, Clayton, Victoria, 3800, Australia.

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August 2018

Generation and characterisation of a parkin-Pacrg knockout mouse line and a Pacrg knockout mouse line.

Authors:

Sarah E M Stephenson Timothy D Aumann Juliet M Taylor Jessica R Riseley Ruili Li Jeffrey R Mann Doris Tomas Paul J Lockhart

Sci Rep 2018 05 14;8(1):7528. Epub 2018 May 14.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Children's Research Institute, Flemington Road, Parkville, Victoria, Australia.

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May 2018

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers.

Authors:

Maheshi Udugama Elaine Sanij Hsiao P J Voon Jinbae Son Linda Hii Jeremy D Henson F Lyn Chan Fiona T M Chang Yumei Liu Richard B Pearson Paul Kalitsis Jeffrey R Mann Philippe Collas Ross D Hannan Lee H Wong

Proc Natl Acad Sci U S A 2018 05 18;115(18):4737-4742. Epub 2018 Apr 18.

Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia;

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May 2018

In depth analysis of the Sox4 gene locus that consists of sense and natural antisense transcripts.

Authors:

King-Hwa Ling Peter J Brautigan Sarah Moore Rachel Fraser Melody Pui-Yee Leong Jia-Wen Leong Shahidee Zainal Abidin Han-Chung Lee Pike-See Cheah Joy M Raison Milena Babic Young Kyung Lee Tasman Daish Deidre M Mattiske Jeffrey R Mann David L Adelson Paul Q Thomas Christopher N Hahn Hamish S Scott

Data Brief 2016 Jun 17;7:282-90. Epub 2016 Feb 17.

Department of Molecular Pathology, The Institute of Medical and Veterinary Science and The Hanson Institute, P.O. Box 14 Rundle Mall Post Office, Adelaide, SA 5000, Australia; School of Medicine, Faculty of Health Sciences, University of Adelaide, Adelaide, SA 5005, Australia.

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June 2016

Derivation of an endogenous small RNA from double-stranded Sox4 sense and natural antisense transcripts in the mouse brain.

Authors:

King-Hwa Ling Peter J Brautigan Sarah Moore Rachel Fraser Pike-See Cheah Joy M Raison Milena Babic Young Kyung Lee Tasman Daish Deidre M Mattiske Jeffrey R Mann David L Adelson Paul Q Thomas Christopher N Hahn Hamish S Scott

Genomics 2016 Mar 21;107(2-3):88-99. Epub 2016 Jan 21.

Department of Molecular Pathology, The Institute of Medical and Veterinary Science and The Hanson Institute, P.O. Box 14 Rundle Mall Post Office, Adelaide, SA 5000, Australia; School of Medicine, Faculty of Health Sciences, University of Adelaide, Adelaide, SA 5005, Australia. Electronic address:

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March 2016

Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres.

Authors:

Maheshi Udugama Fiona T M Chang F Lyn Chan Michelle C Tang Hilda A Pickett James D R McGhie Lynne Mayne Philippe Collas Jeffrey R Mann Lee H Wong

Nucleic Acids Res 2015 Dec 24;43(21):10227-37. Epub 2015 Aug 24.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia

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December 2015

CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells.

Authors:

Fiona T M Chang F Lyn Chan James D R McGhie Maheshi Udugama Lynne Mayne Philippe Collas Jeffrey R Mann Lee H Wong

Nucleic Acids Res 2015 Mar 17;43(5):2603-14. Epub 2015 Feb 17.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia

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March 2015

Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice.

Authors:

Michelle C W Tang Shelley A Jacobs Deidre M Mattiske Yu May Soh Alison N Graham An Tran Shu Ly Lim Damien F Hudson Paul Kalitsis Moira K O'Bryan Lee H Wong Jeffrey R Mann

PLoS Genet 2015 Feb 12;11(2):e1004964. Epub 2015 Feb 12.

Genetics Theme, Murdoch Children's Research Institute, Parkville, Victoria, Australia.

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February 2015

High histone variant H3.3 content in mouse prospermatogonia suggests a role in epigenetic reformatting.

Authors:

Michelle C W Tang Steve Binos Eng K Ong Lee H Wong Jeffrey R Mann

Chromosoma 2014 Dec 10;123(6):587-95. Epub 2014 Jul 10.

Department of Zoology, The University of Melbourne, Gate 12 Royal Parade, Parkville, VIC, 3010, Australia.

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December 2014

Epigenetics and memigenetics.

Authors:

Jeffrey R Mann

Cell Mol Life Sci 2014 Apr 21;71(7):1117-22. Epub 2014 Jan 21.

Theme of Genetics, Murdoch Childrens Research Institute, The Royal Children's Hospital, Flemington Road, Parkville, 3052, VIC, Australia,

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April 2014

PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells.

Authors:

Fiona T M Chang James D McGhie F Lyn Chan Michelle C Tang Melissa A Anderson Jeffrey R Mann K H Andy Choo Lee H Wong

Nucleic Acids Res 2013 Apr 26;41(8):4447-58. Epub 2013 Feb 26.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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April 2013

Conditional allelic replacement applied to genes encoding the histone variant H3.3 in the mouse.

Authors:

Michelle C W Tang Shelley A Jacobs Lee H Wong Jeffrey R Mann

Genesis 2013 Feb 7;51(2):142-6. Epub 2013 Feb 7.

Theme of Genetic Disorders, Murdoch Childrens Research Institute, The Royal Children's Hospital, Victoria, 3052, Australia.

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February 2013

Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells.

Authors:

Jonathan Ip Paul Canham K H Andy Choo Yoshimi Inaba Shelley A Jacobs Paul Kalitsis Deidre M Mattiske Jane Ng Richard Saffery Nicholas C Wong Lee H Wong Jeffrey R Mann

PLoS Genet 2012 Sep 6;8(9):e1002919. Epub 2012 Sep 6.

Theme of Genetic Disorders, Murdoch Childrens Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.

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September 2012

RNA interference in mammalian DNA methylation.

Authors:

Jeffrey R Mann Deidre M Mattiske

Biochem Cell Biol 2012 Feb 17;90(1):70-7. Epub 2011 Oct 17.

Theme of Genetic Disorders, Murdoch Childrens Research Institute, The Royal Children's Hospital, Parkville 3052, Victoria, Australia.

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February 2012

Deep sequencing analysis of the developing mouse brain reveals a novel microRNA.

Authors:

King-Hwa Ling Peter J Brautigan Christopher N Hahn Tasman Daish John R Rayner Pike-See Cheah Joy M Raison Sandra Piltz Jeffrey R Mann Deidre M Mattiske Paul Q Thomas David L Adelson Hamish S Scott

BMC Genomics 2011 Apr 5;12:176. Epub 2011 Apr 5.

Department of Molecular Pathology, SA Pathology and Centre for Cancer Biology, Adelaide, Australia.

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April 2011

Chromosome-wide analysis of parental allele-specific chromatin and DNA methylation.

Authors:

Purnima Singh Xiwei Wu Dong-Hoon Lee Arthur X Li Tibor A Rauch Gerd P Pfeifer Jeffrey R Mann Piroska E Szabó

Mol Cell Biol 2011 Apr 14;31(8):1757-70. Epub 2011 Feb 14.

Department of Molecular and Cellular Biology, Beckman Research Institute, City of Hope, 1450 E. Duarte Road, Duarte, CA 91010, USA.

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April 2011

A genomic imprinting defect in mice traced to a single gene.

Authors:

Altan Rentsendorj Subburaman Mohan Piroska Szabó Jeffrey R Mann

Genetics 2010 Nov 16;186(3):917-27. Epub 2010 Aug 16.

Division of Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010, USA.

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November 2010

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells.

Authors:

Lee H Wong James D McGhie Marcus Sim Melissa A Anderson Soyeon Ahn Ross D Hannan Amee J George Kylie A Morgan Jeffrey R Mann K H Andy Choo

Genome Res 2010 Mar 28;20(3):351-60. Epub 2010 Jan 28.

Chromosome and Chromatin Research, Murdoch Childrens Research Institute, Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Parkville, Victoria 3052, Australia.

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March 2010