Publications by authors named "Jeffrey M Trent"

100Publications

Re-assigning the histologic identities of COV434 and TOV-112D ovarian cancer cell lines.

Gynecol Oncol 2020 Dec 13. Epub 2020 Dec 13.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada; Department of Molecular Oncology, British Columbia Cancer Research Institute, Vancouver, BC, Canada. Electronic address:

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December 2020

Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility.

Int J Cancer 2019 11 18;145(9):2372-2382. Epub 2019 Mar 18.

State Key Laboratory of Genetic Engineering, Zhongshan Hospital, Fudan University, and School of Life Sciences, Fudan University, Shanghai, China.

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November 2019

Molecular Guided Therapy Provides Sustained Clinical Response in Refractory Choroid Plexus Carcinoma.

Front Pharmacol 2017 25;8:652. Epub 2017 Sep 25.

Pediatric Oncology Translational Research Program, Helen DeVos Children's Hospital at Spectrum HealthGrand Rapids, MI, United States.

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September 2017

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

J Pathol 2017 07 2;242(3):371-383. Epub 2017 Jun 2.

Department of Pathology and Laboratory Medicine, University of British Columbia and Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC, Canada.

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July 2017

Promoter Mutations Ablate GABP Transcription Factor Binding in Melanoma.

Cancer Res 2017 04 20;77(7):1649-1661. Epub 2017 Jan 20.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, Maryland.

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April 2017

The influence of clinical and genetic factors on patient outcome in small cell carcinoma of the ovary, hypercalcemic type.

Gynecol Oncol 2016 06 19;141(3):454-460. Epub 2016 Mar 19.

Department of Human Genetics, McGill University, Montreal, QC, Canada; Lady Davis Institute and Segal Cancer Center, Jewish General Hospital, Montreal, QC, Canada; Department of Medical Genetics and Cancer Research Program, Research Institute, McGill University Health Centre, Montreal, QC, Canada. Electronic address:

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June 2016

Toward precision medicine in glioblastoma: the promise and the challenges.

Neuro Oncol 2015 Aug 1;17(8):1051-63. Epub 2015 May 1.

University of California San Francisco, San Francisco, California (M.D.P, J.J.P., A.M.M., S.M.C.); Translational Genomics Research Institute, Phoenix, Arizona (S.A.B., N.L.T., W.D.T., J.A.K., M.E.B., D.W.C., J.D.C., J.M.T.); Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (K.L.L., P.Y.W.); University of Texas Health Science Center, San Antonio, Texas (J.G.K.); Memorial Sloan-Kettering Cancer Center, New York, New York (I.K.M.); The University of Texas M.D. Anderson Cancer Center, Houston, Texas (J.F.d.G.); University of Utah Huntsman Cancer Institute, Salt Lake City, Utah (H.C.); University of California Los Angeles, Los Angeles, California (T.F.C.); Iowa Spine and Brain Institute, Waterloo, Iowa (T.C.R.).

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August 2015

Assessing Combinational Drug Efficacy in Cancer Cells by Using Image-based Dynamic Response Analysis.

Cancer Inform 2015 9;14(Suppl 5):33-43. Epub 2016 Mar 9.

Center for Bioinformatics and Genomic Systems Engineering, Texas A&M Engineering Experiment Station, Texas A&M University, College Station, TX, USA.; Translational Genomics Research Institute, Phoenix, AZ, USA.

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March 2016

Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma.

J Natl Cancer Inst 2015 Feb 13;107(2). Epub 2014 Dec 13.

Affiliations of authors: QIMR Berghofer Medical Research Institute, Brisbane, Australia (LGA, ALP, MG, PJ, JMP, JS, VB, SW, KDR, MSS, GWM, NGM, NKH); Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK (CDRE, TMK, DJA); Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark (KW, AMG); Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK (MH, HSn, DTB, JANB); Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD (JC, KMB); Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología del Principado de Asturias (IUOPA) Universidad de Oviedo, Oviedo, Spain (VQ, AJR, CLO); Cancer Genomics Research Laboratory, NCI Frederick, SAIC-Frederick Inc., Frederick MD (XZ, KJ); Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands (RvD, NAG); Department of Clinical Sciences Lund, Division of Oncology and Pathology, Lund University, Lund, Sweden (HO, CI, ÅB, GJ); Translational Genomics Institute, Phoenix, AZ (JMT); University of Sydney at Westmead Millennium Institute, Westmead, Sydney, NSW, Australia (EAH, HSc, GJM); Melanoma Institute Australia, North Sydney, NSW, Australia (EAH, HSc, GJM).

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February 2015

8q24 risk alleles and prostate cancer in African-Barbadian men.

Prostate 2014 Dec 22;74(16):1579-88. Epub 2014 Sep 22.

Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, Maryland.

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December 2014

A BAP1 mutation in a Danish family predisposes to uveal melanoma and other cancers.

PLoS One 2013 19;8(8):e72144. Epub 2013 Aug 19.

Oncogenomics Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia ; University of Queensland, Brisbane, Queensland, Australia.

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April 2014

The BioIntelligence Framework: a new computational platform for biomedical knowledge computing.

J Am Med Inform Assoc 2013 Jan 2;20(1):128-33. Epub 2012 Aug 2.

The Translational Genomics Research Institute (TGen), Center for BioIntelligence, Phoenix, AZ 85004, USA.

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January 2013

High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells.

Mol Cancer Res 2011 Jun 2;9(6):724-32. Epub 2011 May 2.

Clinical Translational Research Division, Translational Genomics Research Institute, Scottsdale, AZ 85259, USA.

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June 2011

Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis.

Cancer Res 2011 Apr 2;71(8):3162-72. Epub 2011 Feb 2.

State Key Laboratory of Oncology in South China, Departments of Pathology and Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.

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April 2011

Contribution of HPC1 (RNASEL) and HPCX variants to prostate cancer in a founder population.

Prostate 2010 Nov;70(15):1716-27

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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November 2010

Conditioning-based modeling of contextual genomic regulation.

IEEE/ACM Trans Comput Biol Bioinform 2009 Apr-Jun;6(2):310-20

Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843-3128, USA

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August 2009

Functional evidence implicating S100P in prostate cancer progression.

Int J Cancer 2008 Jul;123(2):330-339

Pharmaceutical Genomics Division, The Translational Genomics Research Institute, Scottsdale, AZ.

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July 2008

Adrenocortical carcinoma survival rates correlated to genomic copy number variants.

Mol Cancer Ther 2008 Feb;7(2):425-31

Genetic Basis of Human Disease Division, Translational Genomics Research Institute, 445 North 5th Street, Phoenix, AZ 85004, USA.

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February 2008

Cancer. The gene topography of cancer.

Science 2007 Nov;318(5853):1079-80

Translational Genomics Research Institute, Phoenix, AZ 85004, USA.

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November 2007

Optimization of oligonucleotide microarray fabricated by spotting 65-mer.

Anal Biochem 2007 Sep 8;368(1):61-9. Epub 2007 Jun 8.

Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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September 2007

Performance characteristics of 65-mer oligonucleotide microarrays.

Anal Biochem 2007 Sep 13;368(1):70-8. Epub 2007 May 13.

Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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September 2007

Notch and NOXA-related pathways in melanoma cells.

J Investig Dermatol Symp Proc 2005 Nov;10(2):95-104

Department of Pathology, Oncology Institute, Cardinal Bernardin Cancer Center, Loyola University, Chicago, Illinois 60153-5385, USA.

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November 2005

Oncogenomics 2005 meeting report: dissecting cancer through genome research.

Cancer Res 2005 Oct;65(19):8587-90

Translational Genomics Research Institute, Phoenix, Arizona 85004, USA.

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October 2005

GeneLink: a database to facilitate genetic studies of complex traits.

BMC Genomics 2004 Oct 18;5:81. Epub 2004 Oct 18.

Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892-8000, USA.

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October 2004

Which is better for cDNA-microarray-based classification: ratios or direct intensities.

Bioinformatics 2004 Nov 28;20(16):2513-20. Epub 2004 Sep 28.

Department of Electrical Engineering, Texas A&M University, College Station, TX 78041, USA.

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November 2004

Interaction effect of PTEN and CDKN1B chromosomal regions on prostate cancer linkage.

Hum Genet 2004 Aug 5;115(3):255-62. Epub 2004 Jun 5.

Center for Human Genomics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

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August 2004

Looking beyond morphology: cancer gene expression profiling using DNA microarrays.

Cancer Invest 2003 ;21(6):937-49

Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland, USA.

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February 2004