Publications by authors named "Jeffrey M Gross"

44Publications

Evolution and development of complex eyes: a celebration of diversity.

Development 2020 Oct 13;147(19). Epub 2020 Oct 13.

Departments of Ophthalmology and Developmental Biology, Louis J. Fox Center for Vision Restoration, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA

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October 2020

dnmt1 function is required to maintain retinal stem cells within the ciliary marginal zone of the zebrafish eye.

Sci Rep 2020 07 9;10(1):11293. Epub 2020 Jul 9.

Department of Ophthalmology, Louis J. Fox Center for Vision Restoration, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.

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July 2020

Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure.

Development 2020 07 13;147(21). Epub 2020 Jul 13.

Departments of Ophthalmology and Developmental Biology, Louis J. Fox Center for Vision Restoration, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA

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July 2020

Lysyl hydroxylase 3 is required for normal lens capsule formation and maintenance of lens epithelium integrity and fate.

Dev Biol 2020 02 24;458(2):177-188. Epub 2019 Oct 24.

Department of Medical Neurobiology, Institute for Medical Research - Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel. Electronic address:

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February 2020

Genetic and epigenetic control of retinal development in zebrafish.

Curr Opin Neurobiol 2019 12 27;59:120-127. Epub 2019 Jun 27.

Departments of Ophthalmology, and Developmental Biology, The Louis J. Fox Center for Vision Restoration, The McGowan Institute for Regenerative Medicine, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States. Electronic address:

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December 2019

Zebrafish mab21l2 mutants possess severe defects in optic cup morphogenesis, lens and cornea development.

Dev Dyn 2019 07 21;248(7):514-529. Epub 2019 May 21.

Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas.

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July 2019

Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation.

PLoS Genet 2019 01 29;15(1):e1007939. Epub 2019 Jan 29.

Department of Ophthalmology, Louis J Fox Center for Vision Restoration, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.

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January 2019

Using GAL4-Inducible Transgenics to Modulate Rho GTPase Activity in Zebrafish.

Methods Mol Biol 2018 ;1821:359-370

Departments of Ophthalmology and Developmental Biology, Louis J Fox Center for Vision Restoration, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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March 2019

The cellular bases of choroid fissure formation and closure.

Dev Biol 2018 08 24;440(2):137-151. Epub 2018 May 24.

Molecular Biosciences Department, University of Texas at Austin, Austin, TX 78712, USA; Institute for Cell and Molecular Biology, University of Texas at Austin, TX 78712, USA; Institute for Neuroscience, University of Texas at Austin, Austin, TX 78712, USA. Electronic address:

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August 2018

Tet-mediated DNA hydroxymethylation regulates retinal neurogenesis by modulating cell-extrinsic signaling pathways.

PLoS Genet 2017 Sep 19;13(9):e1006987. Epub 2017 Sep 19.

Department of Molecular Biosciences and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX, United States of America.

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September 2017

Compound heterozygous alterations in intraflagellar transport protein in a child with a novel Joubert and oral-facial-digital overlap syndrome.

Cold Spring Harb Mol Case Stud 2017 07 5;3(4). Epub 2017 Jul 5.

Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892-4472, USA.

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July 2017

The hyaloid vasculature facilitates basement membrane breakdown during choroid fissure closure in the zebrafish eye.

Dev Biol 2016 11 12;419(2):262-272. Epub 2016 Sep 12.

Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin TX, 78712.

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November 2016

Eye development and photoreceptor differentiation in the cephalopod Doryteuthis pealeii.

Development 2016 09 10;143(17):3168-81. Epub 2016 Aug 10.

Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA

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September 2016

A GAL4-inducible transgenic tool kit for the in vivo modulation of Rho GTPase activity in zebrafish.

Dev Dyn 2016 08 17;245(8):844-53. Epub 2016 May 17.

Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas.

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August 2016

In vivo analysis of hyaloid vasculature morphogenesis in zebrafish: A role for the lens in maturation and maintenance of the hyaloid.

Dev Biol 2014 Oct 13;394(2):327-39. Epub 2014 Aug 13.

Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, United States. Electronic address:

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October 2014

Cluap1 is essential for ciliogenesis and photoreceptor maintenance in the vertebrate eye.

Invest Ophthalmol Vis Sci 2014 Jun 26;55(7):4585-92. Epub 2014 Jun 26.

Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, United States.

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June 2014

Expression of the de novo DNA methyltransferases (dnmt3 - dnmt8) during zebrafish lens development.

Dev Dyn 2014 Feb 4;243(2):350-6. Epub 2013 Dec 4.

Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas.

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February 2014

snow white, a zebrafish model of Hermansky-Pudlak Syndrome type 5.

Genetics 2013 Oct 26;195(2):481-94. Epub 2013 Jul 26.

Molecular, Cell and Developmental Biology, Institute for Cell and Molecular Biology, The University of Texas at Austin, Texas 78722.

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October 2013

Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata.

Hum Mol Genet 2013 Sep 12;22(17):3568-82. Epub 2013 May 12.

Section of Molecular Cell and Developmental Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.

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September 2013

An ENU mutagenesis screen in zebrafish for visual system mutants identifies a novel splice-acceptor site mutation in patched2 that results in Colobomas.

Invest Ophthalmol Vis Sci 2012 Dec 13;53(13):8214-21. Epub 2012 Dec 13.

Section of Molecular Cell and Developmental Biology, Institute of Cell and Molecular Biology, The University of Texas at Austin, Texas 78712, USA.

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December 2012

Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina.

Neural Dev 2012 Oct 30;7:33. Epub 2012 Oct 30.

Department of Ophthalmology and Visual Sciences, University of Michigan, W, K, Kellogg Eye Center, 1000 Wall Street, Ann Arbor, MI 48105-0714, USA.

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October 2012

Integrin α5/fibronectin1 and focal adhesion kinase are required for lens fiber morphogenesis in zebrafish.

Mol Biol Cell 2012 Dec 24;23(24):4725-38. Epub 2012 Oct 24.

Section of Molecular Cell and Developmental Biology and Institute for Cell and Molecular Biology, University of Texas at Austin, Austin, TX 78722, USA.

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December 2012

Id2a functions to limit Notch pathway activity and thereby influence the transition from proliferation to differentiation of retinoblasts during zebrafish retinogenesis.

Dev Biol 2012 Nov 8;371(2):280-92. Epub 2012 Sep 8.

Section of Molecular Cell and Developmental Biology, The University of Texas at Austin, Austin, TX 78712, USA.

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November 2012

Ectopic proliferation contributes to retinal dysplasia in the juvenile zebrafish patched2 mutant eye.

Invest Ophthalmol Vis Sci 2011 Nov 17;52(12):8868-77. Epub 2011 Nov 17.

Section of Molecular Cell and Developmental Biology, The University of Texas at Austin, Austin, Texas, USA.

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November 2011

Toward a better understanding of human eye disease insights from the zebrafish, Danio rerio.

Prog Mol Biol Transl Sci 2011 ;100:287-330

University of Texas at Austin, Section of Molecular Cell and Developmental Biology, Austin, Texas, USA.

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July 2011

Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens.

Dev Biol 2011 Feb 30;350(1):50-63. Epub 2010 Nov 30.

Section of Molecular, Cell and Developmental Biology, Institute of Cell and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA.

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February 2011

Id2a influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics.

Development 2010 Nov 13;137(22):3763-74. Epub 2010 Oct 13.

Section of Molecular Cell and Developmental Biology, Institute for Cell and Molecular Biology, The University of Texas at Austin, Austin, TX 78722, USA.

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November 2010

Expanded progenitor populations, vitreo-retinal abnormalities, and Müller glial reactivity in the zebrafish leprechaun/patched2 retina.

BMC Dev Biol 2009 Oct 19;9:52. Epub 2009 Oct 19.

Section of Molecular Cell and Developmental Biology, The University of Texas at Austin, Austin, TX, USA.

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October 2009

Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development.

Development 2009 Aug 1;136(15):2601-11. Epub 2009 Jul 1.

Section of Molecular Cell and Developmental Biology, Institute for Cell and Molecular Biology, The University of Texas at Austin, Austin, TX 78722, USA.

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August 2009

Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closure.

Proc Natl Acad Sci U S A 2009 Feb 26;106(5):1462-7. Epub 2009 Jan 26.

Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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February 2009

The vacuolar-ATPase complex regulates retinoblast proliferation and survival, photoreceptor morphogenesis, and pigmentation in the zebrafish eye.

Invest Ophthalmol Vis Sci 2009 Feb 3;50(2):893-905. Epub 2008 Oct 3.

Section of Molecular Cell and Developmental Biology and Institute for Cell and Molecular Biology, The University of Texas at Austin, Austin, Texas 78712, USA.

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February 2009

Zebrafish mutants as models for congenital ocular disorders in humans.

Mol Reprod Dev 2008 Mar;75(3):547-55

Section of Molecular Cell and Developmental Biology, Institute for Cell and Molecular Biology, Institute of Neuroscience, The University of Texas at Austin, Austin, Texas 78712, USA.

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March 2008

Laminin beta1 and gamma1 containing laminins are essential for basement membrane integrity in the zebrafish eye.

Invest Ophthalmol Vis Sci 2007 Jun;48(6):2483-90

Section of Molecular Cell and Developmental Biology, The University of Texas at Austin, Austin, Texas 78712, USA.

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June 2007

Histological preparation of embryonic and adult zebrafish eyes.

CSH Protoc 2007 Sep 1;2007:pdb.prot4846. Epub 2007 Sep 1.

Section of Molecular Cell and Developmental Biology; University of Texas at Austin, Austin, Texas 78712, USA.

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September 2007

Immunohistochemistry on cryosections from embryonic and adult zebrafish eyes.

CSH Protoc 2007 Jul 1;2007:pdb.prot4779. Epub 2007 Jul 1.

Section of Molecular Cell and Developmental Biology, The University of Texas at Austin, Austin, Texas 78712, USA.

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July 2007

Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium.

Development 2006 Oct 20;133(20):4109-18. Epub 2006 Sep 20.

Section of Molecular Cell and Developmental Biology, Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA.

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October 2006

RhoA regulates initiation of invagination, but not convergent extension, during sea urchin gastrulation.

Dev Biol 2006 Apr 3;292(1):213-25. Epub 2006 Feb 3.

Department of Biology, Developmental, Cell and Molecular Group, Duke University, PO Box 91000, Durham, NC 27708, USA.

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April 2006

Tbx2b is essential for neuronal differentiation along the dorsal/ventral axis of the zebrafish retina.

Proc Natl Acad Sci U S A 2005 Mar 8;102(12):4371-6. Epub 2005 Mar 8.

Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.

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March 2005

Identification of zebrafish insertional mutants with defects in visual system development and function.

Genetics 2005 May 16;170(1):245-61. Epub 2005 Feb 16.

Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

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May 2005

LvTbx2/3: a T-box family transcription factor involved in formation of the oral/aboral axis of the sea urchin embryo.

Development 2003 May;130(9):1989-99

Development, Cell and Molecular Biology Group, Box 91000 LSRC, Duke University, Durham, NC 27710, USA.

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May 2003