Publications by authors named "Jeffrey Lancet"

100Publications

Retrospective Analysis of the Clinical Use and Benefit of Lenalidomide and Thalidomide in Myelofibrosis.

Clin Lymphoma Myeloma Leuk 2020 Dec 16;20(12):e956-e960. Epub 2020 Jul 16.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL. Electronic address:

View Article and Find Full Text PDF
December 2020

Benchmarking treatment effects for patients over 70 with acute myeloid leukemia: A systematic review and meta-analysis.

J Geriatr Oncol 2020 Nov 12;11(8):1293-1308. Epub 2020 Jul 12.

Senior Adult Oncology Program, Moffitt Cancer Center, Tampa, FL, USA; Department of Oncology Sciences, University of South Florida, Tampa, FL, USA. Electronic address:

View Article and Find Full Text PDF
November 2020

Characterization of myelodysplastic syndromes (MDS) with T-cell large granular lymphocyte proliferations (LGL).

Leukemia 2020 11 21;34(11):3097-3099. Epub 2020 Jun 21.

Formerly Department of Malignant Hematology, H. Lee Moffitt Cancer center, Tampa, FL, USA.

View Article and Find Full Text PDF
November 2020

SF3B1 Mutations Negatively Predict for Response to Immunosuppressive Therapy in Myelodysplastic Syndromes.

Clin Lymphoma Myeloma Leuk 2020 06 10;20(6):400-406.e2. Epub 2020 Jan 10.

Malignant Hematology Department, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL. Electronic address:

View Article and Find Full Text PDF
June 2020

Defining Acute Myeloid Leukemia Ontogeny in Older Patients.

Clin Lymphoma Myeloma Leuk 2020 05 9;20(5):312-315. Epub 2019 Nov 9.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL. Electronic address:

View Article and Find Full Text PDF
May 2020

Decoding Bone Marrow Fibrosis in Myelodysplastic Syndromes.

Clin Lymphoma Myeloma Leuk 2020 05 14;20(5):324-328. Epub 2020 Jan 14.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL. Electronic address:

View Article and Find Full Text PDF
May 2020

Liposomal encapsulated cytarabine and daunorubicin (CPX-351) for older patients with acute myeloid leukemia.

Leuk Lymphoma 2020 06 8;61(6):1305-1312. Epub 2020 Feb 8.

Malignant Hematology Department, Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

View Article and Find Full Text PDF
June 2020

Driver mutation-specific clinical and genomic correlates differ between primary and secondary myelofibrosis.

Am J Hematol 2019 12 10;94(12):E314-E317. Epub 2019 Sep 10.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

View Article and Find Full Text PDF
December 2019

Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm.

N Engl J Med 2019 04;380(17):1628-1637

From the University of Texas M.D. Anderson Cancer Center, Houston (N.P., M.D., H.M.K., M.K.); Dana-Farber Cancer Institute (A.A.L.) and Boston University School of Medicine (J.M.S.), Boston, and Veristat, Southborough (J.B.) - all in Massachusetts; H. Lee Moffitt Cancer Center, Tampa, FL (K.L.S., J.E.L.); City of Hope National Medical Center, Duarte, CA (A.S.S.); Ohio State University, Columbus (S.V.); Winship Cancer Institute of Emory University, Atlanta (W.B.); Duke University Medical Center, Durham, NC (D.A.R.); and Roswell Park Comprehensive Cancer Center, Buffalo (E.S.W.), and Stemline Therapeutics, New York (S. Spence, S. Shemesh, C.L.B., I.B.) - both in New York.

View Article and Find Full Text PDF
April 2019

Off-target based drug repurposing opportunities for tivantinib in acute myeloid leukemia.

Sci Rep 2019 01 24;9(1):606. Epub 2019 Jan 24.

Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, 33612, United States.

View Article and Find Full Text PDF
January 2019

Is the overall survival for older adults with AML finally improving?

Authors:
Jeffrey E Lancet

Best Pract Res Clin Haematol 2018 12 20;31(4):387-390. Epub 2018 Sep 20.

Department of Malignant Hematology, Moffitt Cancer Center, 12902 Magnolia Dr, Tampa, FL 33612, USA. Electronic address:

View Article and Find Full Text PDF
December 2018

Acute Myeloid Leukemia: The Good, the Bad, and the Ugly.

Am Soc Clin Oncol Educ Book 2018 May;38:555-573

From the Moffitt Cancer Center, Tampa, FL; CHU Lille, INSERM, Laboratory of Hematology, University of Lille, Lille, France; Hematology Department, Saint-Louis Hospital, Paris Diderot University, Paris, France; Washington University School of Medicine, St. Louis, MO.

View Article and Find Full Text PDF
May 2018

CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemia.

J Clin Oncol 2018 09 19;36(26):2684-2692. Epub 2018 Jul 19.

Jeffrey E. Lancet, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; Geoffrey L. Uy, Washington University School of Medicine, St Louis, MO; Jorge E. Cortes, The University of Texas MD Anderson Cancer Center, Houston, TX; Laura F. Newell, Oregon Health & Science University, Portland, OR; Tara L. Lin, University of Kansas Medical Center, Kansas City, KS; Ellen K. Ritchie, Weill Cornell Medical College, New York; Jonathan E. Kolitz, Northwell Health System, Lake Success; Daniel H. Ryan, University of Rochester, Rochester, NY; Robert K. Stuart, Medical University of South Carolina, Charleston, SC; Stephen A. Strickland, Vanderbilt-Ingram Cancer Center, Nashville, TN; Donna Hogge, Leukemia/Bone Marrow Transplant Program of British Columbia, Vancouver, British Columbia, Canada; Scott R. Solomon, The Leukemia Program at Northside Hospital Cancer Center Institute, Atlanta, GA; Richard M. Stone, Dana-Farber Cancer Institute, Boston, MA; Dale L. Bixby, University of Michigan, Grass Lake, MI; Gary J. Schiller, University of California-Los Angeles, Los Angeles; Matthew J. Wieduwilt, University of California-San Diego, La Jolla; Kamalika Banerjee, Michael Chiarella, Arthur C. Louie, Jazz Pharmaceuticals, Palo Alto; Bruno C. Medeiros, Stanford University School of Medicine, Stanford, CA; and Antje Hoering, Cancer Research and Biostatistics, Seattle, WA.

View Article and Find Full Text PDF
September 2018

CPX-351: changing the landscape of treatment for patients with secondary acute myeloid leukemia.

Future Oncol 2018 May 30;14(12):1147-1154. Epub 2018 Jan 30.

Malignant Hematology, H Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.

View Article and Find Full Text PDF
May 2018

Between a rux and a hard place: evaluating salvage treatment and outcomes in myelofibrosis after ruxolitinib discontinuation.

Ann Hematol 2018 Mar 30;97(3):435-441. Epub 2017 Nov 30.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA.

View Article and Find Full Text PDF
March 2018

ASXL1 frameshift mutations drive inferior outcomes in CMML without negative impact in MDS.

Blood Cancer J 2017 11 27;7(12):633. Epub 2017 Nov 27.

Hematopathology and Laboratory Medicine Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 36612, USA.

View Article and Find Full Text PDF
November 2017

The prognostic value of circulating myeloblasts in patients with myelodysplastic syndromes.

Ann Hematol 2018 Feb 22;97(2):247-254. Epub 2017 Nov 22.

Department of Malignant Hematology, H Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.

View Article and Find Full Text PDF
February 2018

Persistent cytarabine and daunorubicin exposure after administration of novel liposomal formulation CPX-351: population pharmacokinetic assessment.

Cancer Chemother Pharmacol 2018 01 22;81(1):171-178. Epub 2017 Nov 22.

Division of Hematology-Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

View Article and Find Full Text PDF
January 2018

State of the Art Update and Next Questions: Acute Myeloid Leukemia.

Clin Lymphoma Myeloma Leuk 2017 11 19;17(11):703-709. Epub 2017 Oct 19.

Moffitt Cancer Center, Tampa, FL.

View Article and Find Full Text PDF
November 2017

A Phase II Study of CLAG Regimen Combined With Imatinib Mesylate for Relapsed or Refractory Acute Myeloid Leukemia.

Clin Lymphoma Myeloma Leuk 2017 Dec 19;17(12):902-907. Epub 2017 Sep 19.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.

View Article and Find Full Text PDF
December 2017

The Treatment Landscape of Myelofibrosis Before and After Ruxolitinib Approval.

Clin Lymphoma Myeloma Leuk 2017 Dec 5;17(12):e45-e53. Epub 2017 Aug 5.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.

View Article and Find Full Text PDF
December 2017

Treatment Choices: A Quality of Life Comparison in Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome.

Clin Lymphoma Myeloma Leuk 2017 07;17S:S75-S79

Moffitt Cancer Center (MCB)-Malignant Hematology and University of South Florida, Tampa, FL.

View Article and Find Full Text PDF
July 2017

Evidence for Selective Benefit of Sequential Treatment With Hypomethylating Agents in Patients With Myelodysplastic Syndrome.

Clin Lymphoma Myeloma Leuk 2017 04 10;17(4):211-214. Epub 2017 Jan 10.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL. Electronic address:

View Article and Find Full Text PDF
April 2017

What are the most promising new agents in acute myeloid leukemia?

Curr Opin Hematol 2017 03;24(2):99-107

Malignant Hematology Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.

View Article and Find Full Text PDF
March 2017

Eltrombopag Use in Patients With Chronic Myelomonocytic Leukemia (CMML): A Cautionary Tale.

Clin Lymphoma Myeloma Leuk 2016 08;16 Suppl:S64-6

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.

View Article and Find Full Text PDF
August 2016

Clinical prognostic factors and outcomes of essential thrombocythemia when transformed to myelodysplastic syndromes and acute myeloid leukemia.

Leuk Res 2016 Mar 2;42:52-8. Epub 2016 Feb 2.

Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States. Electronic address:

View Article and Find Full Text PDF
March 2016

FLT3 inhibitors for acute myeloid leukemia.

Authors:
Jeffrey E Lancet

Clin Adv Hematol Oncol 2015 Sep;13(9):573-5

Moffitt Cancer Center, University of South Florida College of Medicine, Tampa, Florida.

View Article and Find Full Text PDF
September 2015

Lenalidomide Treatment for Lower Risk Nondeletion 5q Myelodysplastic Syndromes Patients Yields Higher Response Rates When Used Before Azacitidine.

Clin Lymphoma Myeloma Leuk 2015 Nov 2;15(11):705-10. Epub 2015 Sep 2.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.

View Article and Find Full Text PDF
November 2015

Molecular pathology of myelodysplastic syndromes: new developments and implications for diagnosis and treatment.

Leuk Lymphoma 2015 26;56(11):3022-30. Epub 2015 May 26.

a Department of Hematopathology and Laboratory Medicine , H. Lee Moffitt Cancer Center and Research Institute , Tampa , FL , USA.

View Article and Find Full Text PDF
September 2016

WT1 vaccination in AML and MDS: A pilot trial with synthetic analog peptides.

Am J Hematol 2015 Jul 3;90(7):602-7. Epub 2015 May 3.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

View Article and Find Full Text PDF
July 2015

The molecular basis and clinical significance of genetic mutations identified in myelodysplastic syndromes.

Leuk Res 2015 Jan 6;39(1):6-17. Epub 2014 Nov 6.

Department of Hematologic Malignancies, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States.

View Article and Find Full Text PDF
January 2015

Concurrence of B-lymphoblastic leukemia and myeloproliferative neoplasm with copy neutral loss of heterozygosity at chromosome 1p harboring a MPL W515S mutation.

Cancer Genet 2014 Oct-Dec;207(10-12):489-94. Epub 2014 Oct 13.

Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute and the University of South Florida, Tampa, FL, USA. Electronic address:

View Article and Find Full Text PDF
February 2015

Postremission therapy in acute promyelocytic leukemia: room for improvement?

Authors:
Jeffrey E Lancet

J Clin Oncol 2014 Nov 22;32(33):3692-6. Epub 2014 Sep 22.

H. Lee Moffitt Cancer Center, Tampa, FL

View Article and Find Full Text PDF
November 2014

Phase II clinical study of erlotinib for treatment of myelodysplastic syndromes.

Am J Hematol 2014 Aug 16;89(8):809-12. Epub 2014 May 16.

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

View Article and Find Full Text PDF
August 2014

Novel therapeutics in acute myeloid leukemia.

Curr Hematol Malig Rep 2014 Jun;9(2):109-17

, 12902 Magnolia Dr, FOB3-Heme, Tampa, FL, 33612, USA,

View Article and Find Full Text PDF
June 2014

Pretransplantation 5-azacitidine in high-risk myelodysplastic syndrome.

Biol Blood Marrow Transplant 2014 Jun 15;20(6):776-80. Epub 2014 Feb 15.

Department of Blood and Marrow Transplantation, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida. Electronic address:

View Article and Find Full Text PDF
June 2014

New agents: great expectations not realized.

Authors:
Jeffrey E Lancet

Best Pract Res Clin Haematol 2013 Sep 16;26(3):269-74. Epub 2013 Oct 16.

Oncologic Sciences, University of South Florida, Tampa, USA; Department of Malignant Hematology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA. Electronic address:

View Article and Find Full Text PDF
September 2013

Prominent hematogone hyperplasia in BCR-ABL1-positive chronic myelogenous leukemia: mimicking recurrent B-lymphoid blast crisis.

Leuk Lymphoma 2014 Aug 6;55(8):1952-4. Epub 2014 Feb 6.

Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center , Tampa, FL , USA.

View Article and Find Full Text PDF
August 2014