Jeffrey L Saver

Jeffrey L Saver

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Jeffrey L Saver

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Impact of procedural time on clinical and angiographic outcomes in patients with acute ischemic stroke receiving endovascular treatment.

J Neurointerv Surg 2019 Oct 6;11(10):984-988. Epub 2019 Mar 6.

Zeenat Qureshi Stroke Institute, St. Cloud, Minnesota, USA.

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http://dx.doi.org/10.1136/neurintsurg-2018-014576DOI Listing
October 2019

Magnitude of Benefit of Combined Endovascular Thrombectomy and Intravenous Fibrinolysis in Large Vessel Occlusion Ischemic Stroke.

Stroke 2019 Sep 17;50(9):2433-2440. Epub 2019 Jul 17.

From the Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine at the University of California, Los Angeles (D.F.Y.-S., J.L.S.).

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http://dx.doi.org/10.1161/STROKEAHA.118.023120DOI Listing
September 2019

Central Nervous System Electrical Stimulation for Neuroprotection in Acute Cerebral Ischemia.

Stroke 2019 Sep 4:STROKEAHA119025364. Epub 2019 Sep 4.

From the Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine at UCLA (M.B.H., J.H., J.L.S.).

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http://dx.doi.org/10.1161/STROKEAHA.119.025364DOI Listing
September 2019

Blood Pressure Variability Predicts Poor In-Hospital Outcome in Spontaneous Intracerebral Hemorrhage.

Stroke 2019 Aug 20;50(8):2023-2029. Epub 2019 Jun 20.

Department of Statistics and Applied Probability, University of California, Santa Barbara (X.L., A.P.).

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http://dx.doi.org/10.1161/STROKEAHA.119.025514DOI Listing
August 2019

Evidence that Tenecteplase Is Noninferior to Alteplase for Acute Ischemic Stroke.

Stroke 2019 Aug 18;50(8):2156-2162. Epub 2019 Jul 18.

From the Comprehensive Stroke Center and Department of Neurology, Geffen School of Medicine at UCLA, CA.

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http://dx.doi.org/10.1161/STROKEAHA.119.025080DOI Listing
August 2019

Oral short-acting antihypertensive medications and the occurrence of stroke: a nationwide case-crossover study.

Hypertens Res 2019 Jul 12. Epub 2019 Jul 12.

Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1038/s41440-019-0300-0DOI Listing
July 2019

Subject Retention in Prehospital Stroke Research Using a Telephone-Based Physician-Investigator Driven Enrollment Method.

Cerebrovasc Dis Extra 2019 Jul 25;9(2):72-76. Epub 2019 Jul 25.

Keck School of Medicine, Department of Neurology, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1159/000500851DOI Listing
July 2019

eTICI reperfusion: defining success in endovascular stroke therapy.

J Neurointerv Surg 2019 May 7;11(5):433-438. Epub 2018 Sep 7.

Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Foothills Hospital, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1136/neurintsurg-2018-014127DOI Listing
May 2019

Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source.

N Engl J Med 2019 05;380(20):1906-1917

From the University Duisburg-Essen and University Hospital Essen, Essen (H.-C.D.), Boehringer Ingelheim Pharma GmbH K.G., Biberach (C.G.), Boehringer Ingelheim International GmbH, Ingelheim, Faculty of Medicine Mannheim of the University of Heidelberg, Mannheim (M.B.), Kreisklinikum Siegen, Siegen, and the University of Marburg, Marburg (M.G.), University Hospital Erlangen, Erlangen (B.K.), and Johannes Wesling Klinikum Minden and Ruhr University Bochum, Minden (P.D.S.) - all in Germany; Miller School of Medicine, University of Miami, Miami (R.L.S.); University of California at San Francisco, San Francisco (J.D.E.), and the Department of Neurology and Comprehensive Stroke Center, University of California at Los Angeles, Los Angeles (J.L.S.) - both in California; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC (C.B.G.); Feinberg School of Medicine of Northwestern University, Chicago (R.A.B.); International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo (S.U.), and the National Cerebral and Cardiovascular Center, Osaka (K.T.) - both in Japan; Boehringer Ingelheim, Singapore, Singapore (J. Kreuzer); Boehringer Ingelheim, Burlington, ON, Canada (L.C.); Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (D.C.); City Clinical Emergency Care Hospital, Kursk (M.C.), and the Military Medical Academy, St. Petersburg (M.O.) - both in Russia; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia (G.D.); Serviço de Neurologia, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Instituto de Medicina Molecular, University of Lisbon, Lisbon, Portugal (J.M.F.); F. Ass. Mutua Terrassa, Terrassa (J. Krupinski), and Servicio de Neurología, Hospital Universitario Ramón y Cajal (IRYCIS), Departamento de Medicina, Universidad de Alcalá, Madrid (J.M.) - both in Spain; Hallym University Sacred Heart Hospital, Seoul, South Korea (B.-C.L.); KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology, VIB Center for Brain & Disease Research, University Hospitals Leuven, Department of Neurology, Leuven, Belgium (R.L.); and Hospital Policlinico Umberto I, Sapienza University, Rome (D.T.).

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http://dx.doi.org/10.1056/NEJMoa1813959DOI Listing
May 2019

Sphenopalatine Ganglion Stimulation to Augment Cerebral Blood Flow.

Stroke 2019 May 23:STROKEAHA118024582. Epub 2019 May 23.

Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital, Barcelona (C.A.M.).

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http://dx.doi.org/10.1161/STROKEAHA.118.024582DOI Listing
May 2019

A national economic and clinical model for ischemic stroke care development in Saudi Arabia: A call for change.

Int J Stroke 2019 May 23:1747493019851284. Epub 2019 May 23.

7 Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1177/1747493019851284DOI Listing
May 2019

Relation of Admission Blood Pressure to In-hospital and 90-Day Outcomes in Patients Presenting With Transient Ischemic Attack.

Am J Cardiol 2019 Apr 11;123(7):1083-1095. Epub 2019 Jan 11.

Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.amjcard.2018.12.037DOI Listing
April 2019

Use, Temporal Trends, and Outcomes of Endovascular Therapy After Interhospital Transfer in the United States.

Circulation 2019 Mar;139(13):1568-1577

Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, AB, Canada (E.E.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036509DOI Listing
March 2019

Rapid Alteplase Administration Improves Functional Outcomes in Patients With Stroke due to Large Vessel Occlusions.

Stroke 2019 Mar;50(3):645-651

Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, Health Science Centre (M.D.H.), University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1161/STROKEAHA.118.021840DOI Listing
March 2019

Differential Expression of Vascular Endothelial Growth Factor-A Isoforms Between Intracranial Atherosclerosis and Moyamoya Disease.

J Stroke Cerebrovasc Dis 2019 Feb 2;28(2):360-368. Epub 2018 Nov 2.

Department of Neurosurgery, Gonzalez Neurovascular Laboratory, Cedars-Sinai Medical Center, Los Angeles, California; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.10.004DOI Listing
February 2019

Number Needed to Treat: Conveying the Likelihood of a Therapeutic Effect.

JAMA 2019 02;321(8):798-799

Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrance, California.

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http://dx.doi.org/10.1001/jama.2018.21971DOI Listing
February 2019

Components and Trends in Door to Treatment Times for Endovascular Therapy in Get With The Guidelines-Stroke Hospitals.

Circulation 2019 Jan;139(2):169-179

Calgary Stroke Program, Department of Clinical Neurosciences and Radiology, Cumming School of Medicine, Hotchkiss Brain Institute, University of Calgary, Canada (B.K.M., M.G., E.E.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036701DOI Listing
January 2019

Handling of Missing Outcome Data in Acute Stroke Trials: Advantages of Multiple Imputation Using Baseline and Postbaseline Variables.

J Stroke Cerebrovasc Dis 2018 Dec 6;27(12):3662-3669. Epub 2018 Oct 6.

Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine at the University of California, Los Angeles, California.

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https://linkinghub.elsevier.com/retrieve/pii/S10523057183049
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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.08.040DOI Listing
December 2018

Response by Saver et al to Letter Regarding Article, "Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Ischemic Stroke: A Topical Review".

Stroke 2018 12;49(12):e336

Department of Neurology and Comprehensive Stroke Center, Tufts University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1161/STROKEAHA.118.022688DOI Listing
December 2018

Letter by Berry et al Regarding Article, "Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials: A Simulation Study".

Stroke 2018 12;49(12):e337

Department of Neurology, University of California, Los Angeles.

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http://dx.doi.org/10.1161/STROKEAHA.118.022198DOI Listing
December 2018

The Frequency of Substantial Salvageable Penumbra in Thrombectomy-ineligible Patients with Acute Stroke.

J Neuroimaging 2018 Nov 16;28(6):676-682. Epub 2018 Jul 16.

Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine at the University of California-Los Angeles (UCLA), Los Angeles, CA.

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http://dx.doi.org/10.1111/jon.12544DOI Listing
November 2018

Impact of Hyperglycemia According to the Collateral Status on Outcomes in Mechanical Thrombectomy.

Stroke 2018 11;49(11):2706-2714

Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine (D.S.L., J.L.S.), University of California Los Angeles.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.022167
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http://dx.doi.org/10.1161/STROKEAHA.118.022167DOI Listing
November 2018

Relative cerebral blood volume is associated with collateral status and infarct growth in stroke patients in SWIFT PRIME.

J Cereb Blood Flow Metab 2018 10 14;38(10):1839-1847. Epub 2017 Nov 14.

6 Department of Neurology and Neurological Sciences, Stanford Stroke Center, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1177/0271678X17740293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168913PMC
October 2018

Patent foramen ovale increases stroke risk in older people.

Nat Rev Neurol 2018 Oct;14(10):573-574

Comprehensive Stroke Center and Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41582-018-0050-7DOI Listing
October 2018

Striving for Ideal Cardiovascular and Brain Health: It Is Never Too Early or Too Late.

JAMA 2018 08;320(7):645-647

Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2018.11002DOI Listing
August 2018

Microcatheter contrast injection in stent retriever neurothrombectomy is safe and useful: insights from SWIFT PRIME.

J Neurointerv Surg 2018 Jul 10;10(7):615-619. Epub 2017 Nov 10.

Department of Neurology, University of California Los Angeles, Neurovascular Imaging Research Core, Los Angeles, California, USA.

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http://dx.doi.org/10.1136/neurintsurg-2017-013397DOI Listing
July 2018

Mechanical thrombectomy for acute ischemic stroke with occlusion of the M2 segment of the middle cerebral artery: a meta-analysis.

J Neurointerv Surg 2018 Jul 10;10(7):620-624. Epub 2017 Nov 10.

Department of Neurology, University of Texas Health Science Center at Houston, Houston, Texas, USA.

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http://dx.doi.org/10.1136/neurintsurg-2017-013515DOI Listing
July 2018

Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Ischemic Stroke: A Topical Review.

Stroke 2018 06 14;49(6):1541-1548. Epub 2018 May 14.

Department of Neurology and Comprehensive Stroke Center, Tufts University School of Medicine, Boston, MA (D.T.).

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http://dx.doi.org/10.1161/STROKEAHA.117.018153DOI Listing
June 2018

Clinical Significance of Acute and Serial Platelet Function Testing in Acute Ischemic Stroke.

J Am Heart Assoc 2018 06 1;7(11). Epub 2018 Jun 1.

Department of Neurology, Chonnam National University Hospital, Gwangju, Korea.

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http://dx.doi.org/10.1161/JAHA.117.008313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015392PMC
June 2018

Frequency of Patent Foramen Ovale and Migraine in Patients With Cryptogenic Stroke.

Stroke 2018 05 10;49(5):1123-1128. Epub 2018 Apr 10.

From the Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA (B.H.W., Y.M., A.C.C., E.J.S., R.G.F., J.M.T.)

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.117.020160
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http://dx.doi.org/10.1161/STROKEAHA.117.020160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915909PMC
May 2018

Los Angeles Motor Scale to Identify Large Vessel Occlusion: Prehospital Validation and Comparison With Other Screens.

Stroke 2018 03 19;49(3):565-572. Epub 2018 Feb 19.

From the Department of Neurology, Kaiser Permanente Orange County, Anaheim, CA (A.R.N.); Department of Neurology, University of Southern California, Los Angeles (N.S., M.K.-T.); Department of Emergency Medicine and Neurology (S.J.S., S.S.), Department of Emergency (F.D.P.), Department of Neurology (A.R.N., K.S., D.S.L., L.K.S., L.R., M.V.-S., J.L.S.), and Department of Biomathematics (J.G.), University of California, Los Angeles; Los Angeles EMS Agency, Orange County EMS Agency, Santa Ana, CA (S.J.S.); Department of Emergency Medicine, Keck School of Medicine of the University of Southern California and Los Angeles Fire Department (M.E.); Los Angeles County Department of Public Health, CA (F.D.P.); National Institutes of Health, National Institutes of Neurological Disorders and Stroke, Bethesda, MD (R.C.); and Stanford University, CA (S.H.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829024PMC
March 2018

Venous collateral drainage patterns predict clinical worsening in dural venous sinus thrombosis.

J Neurointerv Surg 2018 Feb 6;10(2):171-175. Epub 2017 Mar 6.

Division of NeuroInterventional Radiology, Department of Radiology, University of California Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1136/neurintsurg-2016-012941DOI Listing
February 2018

Association Between Hyperacute Stage Blood Pressure Variability and Outcome in Patients With Spontaneous Intracerebral Hemorrhage.

Stroke 2018 02 4;49(2):348-354. Epub 2018 Jan 4.

From the Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea (P.-W.C.); Department of Neurology, Chonnam National University Hospital, Gwangju, Korea (J.-T.K.); Department of Neurology, University of Southern California, Los Angeles (N.S.); Comprehensive Stroke Center, Division of Emergency Medicine, and Department of Neurology (S.S.), Department of Biomathematics (J.G.), and Comprehensive Stroke Center and Department of Neurology (D.S.L., J.L.S.), David Geffen School of Medicine, University of California, Los Angeles; School of Medicine, Stanford University, CA (S.H.); National Institutes of Neurological Disorders and Stroke, Bethesda, MD (R.C.); Department of Emergency Medicine, Keck School of Medicine of the University of Southern California, Los Angeles (M.E.); Los Angeles Fire Department, CA (M.E.); Los Angeles County Department of Public Health, CA (F.P.); and Department of Emergency Medicine, Los Angeles EMS Agency, Orange County EMS Agency, Harbor-University of California, Los Angeles Medical Center (S.S.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017701DOI Listing
February 2018

Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.

N Engl J Med 2018 01 11;378(1):11-21. Epub 2017 Nov 11.

From the Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, and the Department of Neurology, Emory University School of Medicine, Atlanta (R.G.N., D.C.H., M.R.F.); the Stroke Institute, Departments of Neurology (A.P.J., T.G.J.) and Neurosurgery (B.T.J.), University of Pittsburgh Medical Center, Pittsburgh, and Abington Health, Abington (Q.A.S.) - both in Pennsylvania; the Department of Neuroradiology, Hôpital Gui-de-Chauliac, Montpellier (A.B., V.C.), and the Department of Diagnostic and Therapeutic Neuroradiology (C.C.) and the Neuroimaging Center and Center for Clinical Investigations (J.-M.O.), University Hospital of Toulouse, Toulouse - both in France; OhioHealth Riverside Methodist Hospital, Columbus (R.F.B., N.A.V.), and University Hospitals of Cleveland, Cleveland (C.A.S., A.J.F.) - both in Ohio; Texas Stroke Institute, Dallas-Fort Worth (P.B., A.J.Y.), the Department of Neuroscience, Valley Baptist Medical Center, Harlingen (A.E.H., W.G.T.), and Berry Consultants, Austin (T.G., R.J.L.) - all in Texas; the Department of Neurology and Neurosurgery, University of Miami Miller School of Medicine-Jackson Memorial Hospital, Miami (D.R.Y., A.M.M.), Baptist Health, Jacksonville (R.A.H., A.A.), Memorial Regional Hospital, Hollywood (B.P.M.), and Florida Hospital, Orlando (F.R.H.) - all in Florida; the Stroke Unit, Hospital Vall d'Hebrón (M. Ribo, M. Rubiera), and Hospital Universitari de Bellvitge (P.C.), Barcelona, and the Department of Neuroscience, Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona (M.M.) - all in Spain; the Department of Neurosurgery, State University of New York at Buffalo, Buffalo (E.I.L.); the Department of Interventional Neuroradiology, Royal Melbourne Hospital, Victoria (P.M.); the Departments of Neurology (M.C.) and Neurosurgery (D.K.L.), Rush University Medical Center, Chicago; California Pacific Medical Center (J.D.E.) and the Department of Neurology, University of California, San Francisco (W.S.S.), San Francisco, the Department of Neuroradiology, Kaiser Permanente (L.F.), and the Neurovascular Imaging Research Core, Department of Neurology and Comprehensive Stroke Center (D.S.L.), David Geffen School of Medicine, University of California, Los Angeles (UCLA) (D.S.L., J.L.S.), Los Angeles, Stryker Neurovascular, Fremont (R.S.), and Los Angeles County Harbor-UCLA Medical Center, Torrance (R.J.L.) - all in California; the Departments of Medical Imaging and Surgery (F.L.S., V.M.P.) and Neurology (V.M.P.), Toronto Western Hospital, University Health Network, University of Toronto, Toronto; the Department of Radiology, Erlanger Hospital at the University of Tennessee, Chattanooga (B.W.B.); the Department of Neurology, University of Kansas Medical Center, Kansas City (M.G.A.); and the Neuroscience Center, Capital Health Hospital, Trenton (E.V.), and the JFK Medical Center, Edison (J.F.K.) - both in New Jersey.

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http://dx.doi.org/10.1056/NEJMoa1706442DOI Listing
January 2018

Visual Aids for Patient, Family, and Physician Decision Making About Endovascular Thrombectomy for Acute Ischemic Stroke.

Stroke 2018 01 8;49(1):90-97. Epub 2017 Dec 8.

From the Department of Neurology and Comprehensive Stroke Center (I.T., L.S., D.L., J.L.S.), Departments of Emergency Medicine and Neurology, and Comprehensive Stroke Center (S.S.), and Department of Radiology and Comprehensive Stroke Center (V.S., R.J.), David Geffen School of Medicine, University of California Los Angeles; Hospital General Universitario Gregorio Marañón with the collaboration of Comité ad-hoc de Neurólogos Jóvenes de la Sociedad Española de Neurología, Madrid, Spain (M.V.M.); School of Medicine at Federal University of São João del-Rei (UFSJ), Brazil (M.F.Z.A.); Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA (N.G.); Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, Foothills Hospital (A.D.) and Calgary Stroke Program, Departments of Clinical Neurosciences and Radiology, Seaman Family MR Research Centre, Hotchkiss Brain Institute (M.T.F), University of Calgary, Alberta, Canada; Cerebrovascular Program, Vanderbilt University Medical Center, Nashville, TN (M.G.); Department of Neurology and Neurological Sciences, Stanford Stroke Center, Stanford University School of Medicine, CA (M.G.L.); Department of Neurology and Stroke Center, Oregon Health & Science University, Portland (H.L.); and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (L.S.).

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http://dx.doi.org/10.1161/STROKEAHA.117.018715DOI Listing
January 2018

Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke).

Circulation 2017 Dec 24;136(24):2311-2321. Epub 2017 Sep 24.

Advanced Neuroscience Network/Tenet South Florida, Delray Beach (R.K., N.H.M.-K.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.117.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.028920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732640PMC
December 2017

Increase in Endovascular Therapy in Get With The Guidelines-Stroke After the Publication of Pivotal Trials.

Circulation 2017 Dec 5;136(24):2303-2310. Epub 2017 Oct 5.

Department of Neurology, Massachusetts General Hospital, Boston (L.H.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.031097DOI Listing
December 2017

Trials of Patent Foramen Ovale Closure.

N Engl J Med 2017 12;377(26):2600

David Geffen School of Medicine at UCLA, Los Angeles, CA

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http://dx.doi.org/10.1056/NEJMc1714320DOI Listing
December 2017

Minimal Clinically Important Difference for Safe and Simple Novel Acute Ischemic Stroke Therapies.

Stroke 2017 11 20;48(11):2946-2951. Epub 2017 Sep 20.

From the Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine, University of California, Los Angeles (J.S.C., B.D.K., J.L.S.); Department of Neuroscience, Duke University, Durham, NC (J.S.C.); and Department of Kinesiology, University of Maryland, College Park (B.D.K.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017496DOI Listing
November 2017

Ischemic Strokes Due to Large-Vessel Occlusions Contribute Disproportionately to Stroke-Related Dependence and Death: A Review.

Front Neurol 2017 30;8:651. Epub 2017 Nov 30.

Department of Neurology, University of California Los Angeles Comprehensive Stroke Center, Los Angeles, CA, United States.

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http://journal.frontiersin.org/article/10.3389/fneur.2017.00
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http://dx.doi.org/10.3389/fneur.2017.00651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715197PMC
November 2017

Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke: Primary Results of the STRATIS Registry.

Stroke 2017 10 22;48(10):2760-2768. Epub 2017 Aug 22.

From the Advanced Neuroscience Network/Tenet South Florida (N.H.M.-K., R.K.); St Vincent Mercy Hospital, Toledo, OH (O.O.Z.); Vanderbilt University Medical Center, Nashville, TN (M.T.F., R.C.); University of California Los Angeles (R.J., J.L.S., D.S.L., S. Starkman); Brigham and Women's Hospital, Boston, MA (M.A.A.-S.); Methodist Hospital, Houston, TX (R.P.K.); Florida Hospital Neuroscience Institute, Winter Park (F.R.H., R.H.G.); University of Miami Miller School of Medicine/Jackson Memorial Hospital, FL (D.R.Y., E.C.P.); Norton Neuroscience Institute, Norton Healthcare, Louisville, KY (T.L.Y., S.R.D.); University of Pittsburgh Medical Center, PA (A.P.J.); WellStar Neurosciences Network, WellStar Kennestone Regional Medical Center, Marietta, GA (R.G.); Valley Baptist Medical Center, Harlingen, TX (A.E.H.); St Luke's Hospital of Kansas City, MO (C.O.M.); Oregon Health and Science University Hospital, Portland, OR (H.B.); Emory University School of Medicine, Grady Memorial Hospital, Atlanta, GA (R.G.N., D.C.H.); Baptist Health Lexington/Central Baptist, KY (C.A.G.); South Broward Hospital, Hollywood, FL (B.P.M.); Providence St Vincent Medical Center, Portland, OR (V.D.); Baptist Hospital of Miami, FL (I.L.); St Dominic's-Jackson Memorial Hospital, MS (S.H.M.); University of Tennessee Medical Center, Knoxville (P.K.); Advocate Christ Medical Center, Oak Lawn, IL (T.J.G.); Cleveland Clinic, OH (M.S.H.); Baylor University Medical Center, Dallas, TX (I.T.); OhioHealth Riverside Methodist Hospital, Columbus (N.V.); Memorial Hermann Texas Medical Center, Houston (P.R.C.); Swedish Medical Center First Hill Campus, Seattle, WA (S.J.M.); Maine Medical Center, Portland (R.D.E.); Geisinger Clinic, Danville, PA (C.M.S.); Baptist Medical Center-Jacksonville, FL (E.S.); Baptist Hospital Louisville, KY (A.A.-C.); Barnes Jewish Hospital, St Louis, MO (C.P.D.); Mercy San Juan Medical Center and Mercy General, Carmichael, CA (L.M.); Presence St Joseph Medical Center, Joliet, IL (A. Badruddin); Buffalo General Medical Center, NY (A.H.S.); University of Arizona Medical Center, Tucson (T.M.D.); University of Kentucky Hospital, Lexington (A.A.); Los Robles Medical Center, Thousand Oaks, CA (M.A.T.); Aurora Hospital, Milwaukee, WI (K.A.); West Virginia University/Ruby Memorial Hospital, Morgantown, WV (J.C.); Albany Medical Center, NY (A. Boulos); University of Maryland Medical Center, Baltimore (G.J.); University of Massachusetts Memorial Medical Center, Worcester (A.S.P.); Crouse Hospital, Syracuse, NY (E.M.D.); Virginia Mason Medical Center, Seattle, WA (D.H.R.); Mayo Clinic-Rochester, MN (D.F.K.); Erlanger Medical Center, Chattanooga, TN (B.W.B.); ProMedica Toledo Hospital, OH (M.A.J.); Banner University Medical Center, Phoenix, AZ (P.S.); McLaren Flint, MI (A.M.); California Pacific Medical Center, San Francisco (J.D.E.); University of California, Irvine, Orange (S. Suzuki); St John Providence Hospital, Detroit, MI (R.D.F.); Abbott Northwestern Hospital, Minneapolis, MN (J.E.D.A.); and Carolinas Medical Center, Charlotte, NC (J.C.M.).

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October 2017

A randomized controlled study of intravenous fluid in acute ischemic stroke.

Clin Neurol Neurosurg 2017 Oct 1;161:98-103. Epub 2017 Sep 1.

Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine, University of California, Los Angeles, CA, United States.

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October 2017

Direct Mechanical Thrombectomy Versus Combined Intravenous and Mechanical Thrombectomy in Large-Artery Anterior Circulation Stroke: A Topical Review.

Stroke 2017 10 8;48(10):2912-2918. Epub 2017 Sep 8.

From the Department of Neurology (U.F.), and Department of Diagnostic and Interventional Neuroradiology (J.G.), Inselspital, University Hospital Bern, Switzerland; University of Bern, Switzerland (U.F., J.G.); Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technical University Munich, Germany (J.K.); Division of Neuroradiology, Department of Medical Imaging (V.M.P.) and Division of Neurosurgery, Department of Surgery (V.M.P.), Toronto Western Hospital, University Health Network, Ontario, Canada; Department of Radiology and Neuroradiology, Alfried Krupp Krankenhaus Essen, Germany (R.C.); Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York (A.S.); Vanderbilt University Medical Center, Nashville, TN (M.F.); Department of Diagnostic and Therapeutic Neuroradiology, University Hospital of Toulouse, France (C.C.); University Hospitals Case Medical Center, Neurological Institute, Case Western Reserve University, Cleveland, OH (A.F.); and UCLA Comprehensive Stroke Center, Geffen School of Medicine at UCLA, University of California, Los Angeles (J.L.S).

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October 2017

Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin: A Systematic Review and Meta-Analysis.

Stroke 2017 09 12;48(9):2610-2613. Epub 2017 Jul 12.

From the Department of Neurology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan (M.L., Y.-L.W.); Stroke Center, University of California, Los Angeles (J.L.S., N.M.R.); Department of Neurology, Ilsan Paik Hospital, Inje University, Gimhae, South Korea (K.-S.H.); and Department of Neurology, Medical University of South Carolina, Charleston (B.O.).

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September 2017

Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke.

N Engl J Med 2017 09;377(11):1022-1032

From the University of California, Los Angeles (UCLA), Ronald Reagan UCLA Medical Center, Los Angeles (J.L.S.); University of Colorado, Denver, and University of Colorado Hospital, Aurora (J.D.C.), and South Denver Cardiology, Swedish Medical Center, Littleton (L.A.M.) - all in Colorado; Tufts University, Tufts Medical Center, Boston (D.E.T.); University of Texas, Memorial Hermann Heart and Vascular Institute, Houston (R.W.S.); Medical College of Wisconsin, Milwaukee (D.S.M.); and University of Washington, Seattle (D.L.T.).

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September 2017

Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Stroke Thrombolysis.

Stroke 2017 08;48(8):2084-2090

From the Stroke Research Centre, UCL Institute of Neurology, London, United Kingdom (A.C., D.W., D.J.W.); Hemorrhagic Stroke Research Group, Massachusetts General Hospital, Boston (A.C.); Departments of Neurology and Radiology, Hôpital Sainte-Anne, Université Paris Descartes, France (G.T., C.O., M.E.-G., J.-C.B.); Department of Neurology, the 2nd Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China (S.Y., M.L.); Department of Neurology and Center for Stroke Research, Charite Universitätsmedizin, Berlin, Germany (J.F.S., H.E., C.H.N.); Department of Diagnostic and Interventional Neuroradiology, and Neurology, Inselspital, University Hospital Bern, Switzerland (P.P.K.-G., M.E.-K., H.P.M., S.J.); Department of Neurology, Tokai University School of Medicine, Japan (W.T., Y.M., S.T.); Department of Neurology, University of Arizona, Tucson (C.S.K.); UCLA Comprehensive Stroke Center, Geffen School of Medicine, Los Angeles (J.L.S.); Univ. Lille, Inserm, CHU Lille, U1171, Degenerative and Vascular Cognitive Disorders, France (A.S., S.M., C.C.); Department of Neurology, Austin Health and Florey Institute, Heidelberg, Victoria, Australia (V.T.); Department of Statistical Science, University College London, United Kingdom (Z.F., G.A.); Department of Medicine (Neurology), McMaster University and Population Health Research Institute, Hamilton, Ontario, Canada (A.S.); Stanford Stroke Center, Palo Alto, CA (G.W.A.); Division of Neurology, Stroke and Cerebrovascular Health Program, University of British Columbia Hospital, Vancouver, Canada (O.R.B.); Lysholm Department of Neuroradiology, National Hospital, London, United Kingdom (H.R.J.); Department of Neurological Science, Nippon Medical School Graduate School of Medicine, Tokyo, Japan (J.A., K.K.); and Department of Rehabilitation Medicine, the Jikei University School of Medicine, Tokyo, Japan (W.K.).

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August 2017

Paramedic Initiation of Neuroprotective Agent Infusions: Successful Achievement of Target Blood Levels and Attained Level Effect on Clinical Outcomes in the FAST-MAG Pivotal Trial (Field Administration of Stroke Therapy - Magnesium).

Stroke 2017 07 5;48(7):1901-1907. Epub 2017 Jun 5.

From the David Geffen School of Medicine, University of California Los Angeles (K.S., S. Starkman, L.S., D.L., L.R., M.V.-S., J.L.S.); Keck School of Medicine, University of Southern California, Los Angeles (N.S.); Los Angeles Fire Department, CA (M.E.); Los Angeles EMS Agency, Santa Fe Springs, CA (S. Stratton); Orange County EMS Agency, Santa Ana, CA (F.P.); National Institute of Neurological Disorders and Stroke, Bethesda, MD (R.C.); and Stanford University, CA (S.H.).

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July 2017

Response by Lee et al to Letter Regarding Article, "Pioglitazone for Secondary Stroke Prevention: A Systematic Review and Meta-Analysis".

Stroke 2017 07 15;48(7):e172. Epub 2017 Jun 15.

Department of Neurology, Medical University of South Carolina, Charleston.

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July 2017

Efficacy of Stent-Retriever Thrombectomy in Magnetic Resonance Imaging Versus Computed Tomographic Perfusion-Selected Patients in SWIFT PRIME Trial (Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke).

Stroke 2017 06 2;48(6):1560-1566. Epub 2017 May 2.

From the Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, CA (G.W.A.); Department of Radiology (M.G.) and Department of Clinical Neurosciences (M.G.), University of Calgary, Alberta, Canada; Division of Interventional Neuroradiology (R.J.) and Department of Neurology and Comprehensive Stroke Center, David Geffen School of Medicine (J.L.S.), University of California Los Angeles; Department of Neuroradiology, Hôpital Gui de Chauliac, Montpellier, France (A.B., N.M.d.C.); Department of Neurology, University Hospital of University Duisburg-Essen, Germany (H.-C.D.); Department of Neurosurgery, State University of New York at Buffalo (E.I.L.); Division of Neuroradiology and Division of Neurosurgery, Department of Medical Imaging (V.M.P.) and Department of Surgery (V.M.P.), Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada; Department of Diagnostic and Therapeutic Neuroradiology, University Hospital of Toulouse, France (C.C.); and Department of Neurology and Neurosurgery, University of Miami Miller School of Medicine, FL (D.R.Y.).

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June 2017

The American Heart Association's Get With the Guidelines (GWTG)-Stroke development and impact on stroke care.

Stroke Vasc Neurol 2017 Jun 29;2(2):94-105. Epub 2017 May 29.

Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600018PMC
June 2017

A Dedicated Spanish Language Line Increases Enrollment of Hispanics Into Prehospital Clinical Research.

Stroke 2017 05 7;48(5):1389-1391. Epub 2017 Apr 7.

From the Departments of Neurology (N.S., L.R., M.K.-T.) and Emergency Medicine (M.E.), University of Southern California, Los Angeles; UCLA Stroke Center, Los Angeles, CA (D.S.L., S.S., L.K.S., L.R., M.V.-S., J.L.S.); School of Public Health, University of California Los Angeles (S.S.); Los Angeles County Fire Department, CA (F.D.P.); Stanford University, CA (S.H.); and National Institutes of Health, Bethesda, MD (R.C.).

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May 2017

Delays in Door-to-Needle Times and Their Impact on Treatment Time and Outcomes in Get With The Guidelines-Stroke.

Stroke 2017 04 22;48(4):946-954. Epub 2017 Feb 22.

From the Department of Clinical Neurosciences, Hotchkiss Brian Institute, University of Calgary, Canada (N.K., M.D.H., E.E.S.); Duke Clinical Research Institute, Duke University, Durham, NC (S.S., Y.X., R.M.); Department of Neurology, Duke University Medical Center, Durham, NC (Y.X.); Department of Biostatistics and Bioinformatics, Duke University, Durham, NC (R.M.); Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, Boston, MA (D.L.B.); Department of Neurology (J.L.S.) and Division of Cardiology (G.C.F.), University of California Los Angeles; Department of Epidemiology, Michigan State University, East Lansing (M.J.R.); and Department of Neurology, Massachusetts General Hospital, Boston (L.H.S.).

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April 2017

Predictive Value of RAPID Assessed Perfusion Thresholds on Final Infarct Volume in SWIFT PRIME (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment).

Stroke 2017 04 10;48(4):932-938. Epub 2017 Mar 10.

From the Department of Neurosurgery, University of South Florida, Tampa (M.M.); Department of Neurosurgery, University at Buffalo, NY (E.I.L., A.H.S.); Department of Neurology, David Geffen School of Medicine (J.L.S.) and Division of Interventional Neuroradiology (R.J.), University of California, Los Angeles; Departments of Radiology and Clinical Neurosciences, University of Calgary, Alberta, Canada (M.G.); Department of Neuroradiology, Gui de Chauliac Hospital, Montpellier, France (A.B.); Department of Diagnostic and Therapeutic Neuroradiology, University Hospital of Toulouse, France (C.C.); and Stanford Stroke Center, Stanford University School of Medicine, CA (G.W.A.).

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April 2017

Combined Intravenous Thrombolysis and Thrombectomy vs Thrombectomy Alone for Acute Ischemic Stroke: A Pooled Analysis of the SWIFT and STAR Studies.

JAMA Neurol 2017 Mar;74(3):268-274

Division of Neuroradiology, Department of Medical Imaging, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada13Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamaneurol.2016.5374DOI Listing
March 2017

Multiparametric Magnetic Resonance Imaging for Prediction of Parenchymal Hemorrhage in Acute Ischemic Stroke After Reperfusion Therapy.

Stroke 2017 03 30;48(3):664-670. Epub 2017 Jan 30.

From the Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (K.N.); the Departments of Neurology and Radiology, University of Arizona, Tucson (J.R.K., C.S.K.); the Departments of Radiology and Neurosurgery (R.J.), Biomathematics (J. Gornbein), Neurology (D.S.L., J.L.S.), and Emergency Medicine and Neurology (J. Guzy, S.S.), University of California, Los Angeles; the Departments of Neurology (Z.A.) and Radiology (L.F.), Kaiser Permanente, Los Angeles, CA; the Departments of Neurosciences and the Stroke Center University of California, San Diego (B.C.M.); the Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston (L.H.S.); Texas Stroke Institute, Dallas (A.J.Y.); the Departments of Neurology (R.S.M.) and Neurological Surgery and Radiology (P.M.M.), Columbia University College of Physicians and Surgeons, New York, NY; the Departments of Neurology and Neurosurgery, University of Miami, Jackson Memorial Hospital, FL (D.R.Y.); and the Departments of Radiology and Neurology Stanford University, CA (M.W.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325250PMC
March 2017

Mobile stroke units for prehospital thrombolysis, triage, and beyond: benefits and challenges.

Lancet Neurol 2017 03 15;16(3):227-237. Epub 2017 Feb 15.

Stroke Center, University of California Los Angeles, Los Angeles, CA, USA.

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March 2017

Time to Endovascular Thrombectomy for Acute Stroke-Reply.

JAMA 2017 03;317(11):1175-1176

Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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March 2017

Penumbral salvage and thrombolysis outcome: a drop of brain, a week of life.

Authors:
Jeffrey L Saver

Brain 2017 03;140(3):519-522

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March 2017

Effect of statin use on clinical outcomes in ischemic stroke patients with atrial fibrillation.

Medicine (Baltimore) 2017 Feb;96(5):e5918

aDepartment of Neurology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, Chiayi Branch bDepartment of Public Health, China Medical University, Taichung, Taiwan cStroke Center, Geffen School of Medicine, University of California, Los Angeles, CA dDepartment of Healthcare Management, Chang Gung University, Taoyuan, Taiwan eDepartment of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, SC.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293432PMC
February 2017