Publications by authors named "Jeffrey L Bennett"

100Publications

The changing landscape of optic neuritis: a narrative review.

J Neurol 2021 Jan 3. Epub 2021 Jan 3.

Departments of Clinical Neurosciences and Surgery (Ophthalmology), University of Calgary, Calgary, AB, Canada.

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January 2021

Differential Effects of Fingolimod and Natalizumab on B Cell Repertoires in Multiple Sclerosis Patients.

Neurotherapeutics 2020 Nov 30. Epub 2020 Nov 30.

Department of Neurology, University of Colorado Anschutz Medical Campus, 12700 East 19th Avenue, Aurora, Colorado, 80045, USA.

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November 2020

Interleukin-6 in neuromyelitis optica spectrum disorder pathophysiology.

Neurol Neuroimmunol Neuroinflamm 2020 09 20;7(5). Epub 2020 Aug 20.

From the Department of Multiple Sclerosis Therapeutics (K.F.), Fukushima Medical University School of Medicine; and Multiple Sclerosis and Neuromyelitis Optica Center, Southern TOHOKU Research Institute for Neuroscience, Koriyama, Japan; Departments of Neurology and Ophthalmology (J.L.B.), Programs in Neuroscience and Immunology, School of Medicine, University of Colorado, Aurora; Department of Neurology (J.S.), Hôpital de Hautepierre, Strasbourg Cedex, France; Chugai Pharmaceutical Co. (M.H.), Ltd, Tokyo, Japan; Department of Neurology (I.K.), St. Josef Hospital, Ruhr University Bochum; Marianne-Strauß-Klinik (I.K.), Behandlungszentrum Kempfenhausen für Multiple Sklerose Kranke gGmbH, Berg, Germany; Department of Neurology (B.G.W.), Mayo Clinic, Rochester, MN; ApotheCom (D.K., T.M.), London, UK; and Department of Immunology (T.Y.), National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan.

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September 2020

Considerations for the Treatment of Inflammatory Neuro-Ophthalmologic Disorders During the COVID-19 Pandemic.

J Neuroophthalmol 2020 09;40(3):305-314

Departments of Ophthalmology (YMP, JLB, PSS, VSP), Neurology (YMP, JLB, PSS, VSP), and Neurosurgery (PSS), University of Colorado School of Medicine, Aurora, Colorado; and Programs in Neuroscience and Immunology (JLB), University of Colorado School of Medicine, Aurora, Colorado.

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September 2020

Steroid-sparing maintenance immunotherapy for MOG-IgG associated disorder.

Neurology 2020 07 17;95(2):e111-e120. Epub 2020 Jun 17.

From the Departments of Ophthalmology (J.J.C., M.T.B.), Neurology (J.J.C., E.P.F., M.T.B., J.J., D.D., A.S.L.C., B.G.W., A.M., J.-M.T., V.A.L., C.F.L., A.K., S.J.P.), Laboratory Medicine and Pathology (E.P.F., J.J., D.D, J.P.F., A.M., V.A.L., S.J.P.), and Immunology (V.A.L.) and Center for MS and Autoimmune Neurology (E.P.F., D.D., B.G.W., A.M., V.A.L., C.F.L., A.K., S.J.P.), Mayo Clinic, Rochester, MN; Department of Ophthalmology and Visual Neurosciences (C.M.M., M.S.L.), University of Minnesota, Minneapolis; Departments of Neurology and Ophthalmology (J.L.B., V.S.P.), University of Colorado Denver School of Medicine, Aurora; Departments of Ophthalmology and Visual Sciences and Neurology (G.V.S.), Washington University, St. Louis School of Medicine, MO; Departments of Ophthalmology and Visual Science and Neurology (O.-O.O.A.), McGovern Medical School, Houston, TX; Departments of Neurology, Neurosurgery, and Neuro-Ophthalmology (E.R.E.), Mayo Clinic, Jacksonville, FL; Departments of Ophthalmology (M.D.A.) and Neurology (D.M.W.), Mayo Clinic, Scottsdale, AZ; Bascom Palmer Eye Institute (B.L.L.), University of Miami, FL; Department of Neurology and Ophthalmology (H.M., S.B.), Stanford University, Palo Alto, CA; Neuro-Ophthalmology (A.L.G.), Kaiser Permanente, Northern California, Vallejo; Department of Ophthalmology (V.S.), Baylor College of Medicine/Texas Children's Hospital, Houston; Department of Ophthalmology (G.A., D.M.C.), Massachusetts Eye and Ear Infirmary/Harvard Medical School, Boston; Department of Ophthalmology (G.H.), Boston Children's Hospital, Harvard Medical School, MA; and Neuro-Ophthalmology Unit (H.S.-K.), Department of Ophthalmology, Rabin Medical Center, Sackler School of Medicine, Tel Aviv University, Israel.

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July 2020

Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised, phase 2 trial.

Lancet Neurol 2020 05;19(5):391-401

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China; China National Clinical Research Center for Neurological Diseases, Advanced Innovation Center for Human Brain Protection, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address:

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May 2020

Affinity-matured 'aquaporumab' anti-aquaporin-4 antibody for therapy of seropositive neuromyelitis optica spectrum disorders.

Neuropharmacology 2020 01 22;162:107827. Epub 2019 Oct 22.

Departments of Medicine and Physiology, University of California, San Francisco, CA, 94143, USA. Electronic address:

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January 2020

Optic Neuritis.

Continuum (Minneap Minn) 2019 Oct;25(5):1236-1264

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October 2019

Novel clinical features of glycine receptor antibody syndrome: A series of 17 cases.

Neurol Neuroimmunol Neuroinflamm 2019 09 1;6(5):e592. Epub 2019 Jul 1.

Department of Neurology (A.L.P., M.K., M.P.W., J.L.B., M.A.L., L.S., T.L.S.), University of Colorado, Aurora; Department of Neurology (A.L.P., J.E.A.W., M.M.P.S., S.L.C.), University of Utah; Department of Ophthalmology (J.E.A.W.), Moran Eye Center, University of Utah, Salt Lake City; Department of Ophthalmology and Program in Neuroscience (J.L.B.), University of Colorado; Department of Neurology (T.L.S.), Children's Hospital Colorado, Aurora; and Department of Veterans Affairs (M.M.P.S., S.L.C.), George E. Wahlen Veterans Affairs Medical Center, Salt Lake City, UT.

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September 2019

Collaborative International Research in Clinical and Longitudinal Experience Study in NMOSD.

Neurol Neuroimmunol Neuroinflamm 2019 09 28;6(5):e583. Epub 2019 Jun 28.

University of Utah School of Medicine (L.J.C., J.W.R., J.S.A., A.M.J., R.K., B.M., M.P., R.E., J.Y., S.M.), Salt Lake City; Division of Neuroimmunology and Multiple Sclerosis Center (M.H.H.), Department of Neurology and Neurological Sciences, Stanford University; Department of Neurology and Neurological Sciences (A.J.T.), Stanford School of Medicine, CA; Department of Neurology, Johns Hopkins University School of Medicine (M.L., M.A.M., J.C.), Baltimore, MD; Departments of Neurology and Ophthalmology (J.L.B., R.J., M.B.-G.), University of Colorado School of Medicine, Aurora; Department of Medicine & Neurology (A.L.T., R.L.C., L.E.L., J.J.S., K.M.), University of British Columbia, Vancouver, Canada; NYU Langone Health (I.K., Z.R., A.R.), New York; Department of Neurology, Cedars-Sinai Medical Center (N.L.S.), Los Angeles, CA; Mellen Center for MS Treatment and Research (S.M.P., J.A.C., D.I., J.L.S.), Neurological Institute, Cleveland Clinic, OH; Icahn School of Medicine at Mount Sinai (I.K.S.), New York; Multiple Sclerosis Center (P.R.), Swedish Neuroscience Institute, Seattle, WA; Department of Neurology (L.A., A.P., E.A.), Keck School of Medicine, University of Southern California, Los Angeles; Department of Neurology (T.C., D.S.M.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Neurology (E.C.K., A.W.R.), Massachusetts General Hospital, Harvard Medical School, Boston; Department of Neurology (C.S.R., K.B.O., L.L., K.E.N.), Columbia University Medical Center; Weill Cornell Medicine (M.M.N., C.E., M.K.-H., M.M.), New York; Department of Neurology (L.T.), Division of Multiple Sclerosis, University of Miami Miller School of Medicine, FL; PPD (A.R., A.G.), Wilmington, NC; The Guthy-Jackson Charitable Foundation (M.K.B., R.R.R., D.W. Behne., D.W. Blackway, B.C., J.S., J.M.B.), Beverly Hills; Departments of Medicine and of Molecular Pharmacology (T.F.B.), Stanford University School of Medicine, CA; Kellogg Eye Center (T.J.S.), University of Michigan Medical School, Ann Arbor; Department of Medicine, University of California, Los Angeles (M.R.Y.); and Harbor-UCLA Medical Center/LABioMed (M.R.Y.), Torrance, CA.

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September 2019

Concentration-dependent effects of CSF1R inhibitors on oligodendrocyte progenitor cells ex vivo and in vivo.

Exp Neurol 2019 08 25;318:32-41. Epub 2019 Apr 25.

Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA; Department of Ophthalmology, University of Colorado School of Medicine, Aurora, CO, USA; Program in Neuroscience, University of Colorado School of Medicine, Aurora, CO, USA. Electronic address:

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August 2019

Distinct patterns of glia repair and remyelination in antibody-mediated demyelination models of multiple sclerosis and neuromyelitis optica.

Glia 2018 12 21;66(12):2575-2588. Epub 2018 Sep 21.

Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado.

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December 2018

Acute Management of Optic Neuritis: An Evolving Paradigm.

J Neuroophthalmol 2018 09;38(3):358-367

Departments of Neurology (LH, JLB) and Ophthalmology (JLB), University of Colorado Denver, Aurora, Colorado; and Program in Neuroscience (JLB), University of Colorado Denver, Aurora, Colorado.

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September 2018

Mutations of Recombinant Aquaporin-4 Antibody in the Fc Domain Can Impair Complement-Dependent Cellular Cytotoxicity and Transplacental Transport.

Front Immunol 2018 13;9:1599. Epub 2018 Jul 13.

The Feinstein Institute for Medical Research, The Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, Northwell Health System, Manhasset, NY, United States.

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July 2018

Comparative molecular dynamics study of neuromyelitis optica-immunoglobulin G binding to aquaporin-4 extracellular domains.

Biochim Biophys Acta Biomembr 2017 Aug 3;1859(8):1326-1334. Epub 2017 May 3.

Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari 'Aldo Moro', via Orabona, 4, 70126 Bari, Italy; Centro Ricerche TIRES, Università degli Studi di Bari "Aldo Moro", via Amendola 173, I-70126 Bari, Italy. Electronic address:

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August 2017

Determining the Spatial Relationship of Membrane-Bound Aquaporin-4 Autoantibodies by STED Nanoscopy.

Biophys J 2017 Apr;112(8):1692-1702

Department of Neurology, University of Colorado Anschutz Medical Campus, Aurora, Colorado; Department of Ophthalmology, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Electronic address:

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April 2017

Neuromyelitis Optica: Deciphering a Complex Immune-Mediated Astrocytopathy.

J Neuroophthalmol 2017 09;37(3):291-299

Departments of Neurology (JLB, GPO) and Ophthalmology (JLB), University of Colorado, School of Medicine, Aurora, Colorado; and Program in Neuroscience (JLB), University of Colorado, School of Medicine, Aurora, Colorado.

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September 2017

Myelin-specific multiple sclerosis antibodies cause complement-dependent oligodendrocyte loss and demyelination.

Acta Neuropathol Commun 2017 03 24;5(1):25. Epub 2017 Mar 24.

Department of Neurology, University of Colorado, School of Medicine, 12700 E. 19th Ave, Aurora, CO, USA.

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March 2017

Deletional tolerance prevents AQP4-directed autoimmunity in mice.

Eur J Immunol 2017 03 25;47(3):458-469. Epub 2017 Jan 25.

Klinikum rechts der Isar, Department of Neurology, Technical University of Munich, Munich, Germany.

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March 2017

Variable sensitivity to complement-dependent cytotoxicity in murine models of neuromyelitis optica.

J Neuroinflammation 2016 12 1;13(1):301. Epub 2016 Dec 1.

Department of Neurology, University of Colorado, School of Medicine, 12700 E. 19th Ave, Aurora, CO, USA.

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December 2016

Efficacy of Polyvalent Human Immunoglobulins in an Animal Model of Neuromyelitis Optica Evoked by Intrathecal Anti-Aquaporin 4 Antibodies.

Int J Mol Sci 2016 Aug 26;17(9). Epub 2016 Aug 26.

Hans-Berger Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.

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August 2016

Finding NMO: The Evolving Diagnostic Criteria of Neuromyelitis Optica.

J Neuroophthalmol 2016 09;36(3):238-45

Departments of Neurology, Ophthalmology, and Program in Neuroscience, University of Colorado Denver, Aurora, Colorado.

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September 2016

A comprehensive transcriptional map of primate brain development.

Nature 2016 07 13;535(7612):367-75. Epub 2016 Jul 13.

Allen Institute for Brain Science, Seattle, Washington 98109, USA.

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July 2016

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases.

Cell Rep 2016 07 23;16(2):314-322. Epub 2016 Jun 23.

Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany; Institute of Neuronal Cell Biology, Technical University Munich, 80805 Munich, Germany; German Center for Neurodegenerative Disease (DZNE), 6250 Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany. Electronic address:

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July 2016

Autoantibody to MOG suggests two distinct clinical subtypes of NMOSD.

Sci China Life Sci 2016 Dec 26;59(12):1270-1281. Epub 2016 Feb 26.

Departments of Neurology and Immunology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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December 2016

Sphenoid Wing Meningioma With Extraocular Muscle Involvement Mimicking Idiopathic Orbital Inflammation.

Ophthalmic Plast Reconstr Surg 2017 May/Jun;33(3S Suppl 1):S97-S99

Departments of *Ophthalmology, †Pathology, and ‡Neurology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, U.S.A.

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September 2017

The Ins and Outs of B Cells in Multiple Sclerosis.

Front Immunol 2015 5;6:565. Epub 2015 Nov 5.

Department of Neurology, University of Colorado Denver , Aurora, CO , USA ; Department of Ophthalmology, University of Colorado Denver , Aurora, CO , USA ; Program in Neuroscience, University of Colorado Denver , Aurora, CO , USA.

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November 2015

Update on biomarkers in neuromyelitis optica.

Neurol Neuroimmunol Neuroinflamm 2015 Aug 23;2(4):e134. Epub 2015 Jul 23.

Stanford University (E.M., M.H.H.), Stanford, CA; Johns Hopkins University (M.L.), Baltimore, MD; University of Oxford (P.J.W.), UK; Tohoku University (D.K.S.), Sendai, Japan; University of São Paulo (D.K.S.), Brazil; University of Colorado (J.L.B.), Denver; Mt. Sinai University (G.R.J.), New York, NY; Thomas Jefferson University (D.C.H.), Philadelphia, PA; IDIBAPS (A.S.), Barcelona, Spain; Montreal Neurological Institute and Hospital (A.B.-O.), McGill University, Montreal, Quebec, Canada; Research Institute and Hospital of National Cancer Center (H.J.K.), Goyang, Korea; KS Hegde Medical Academy (L.P.), Nitte University, Mangalore, India; Oxford University Hospital (M.I.L.), Oxford, UK; University of Southern Denmark (N.A.), Odense; Vejle Hospital (N.A.), Denmark; University Hospital (N.K.), Marrakech, Morocco; MS Center (R.H.), Erasmus MC University Medical Center, Rotterdam, the Netherlands; Service de Neurologie A (R.M.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France; Molecular Neuroimmunology (S.J.), Department of Neurology, University Hospital Heidelberg, Germany; Tandem Labs (J.M.), San Diego, CA; University of Michigan Medical School (T.J.S.), Ann Arbor, MI; and David Geffen School of Medicine (M.R.Y.), University of California, Los Angeles.

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August 2015

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders.

Neurology 2015 Jul 19;85(2):177-89. Epub 2015 Jun 19.

From the Departments of Neurology (D.M.W.) and Library Services (K.E.W.), Mayo Clinic, Scottsdale, AZ; the Children's Hospital of Philadelphia (B.B.), PA; the Departments of Neurology and Ophthalmology (J.L.B.), University of Colorado Denver, Aurora; the Service de Neurologie (P.C.), Centre Hospitalier Universitaire de Fort de France, Fort-de-France, Martinique; Department of Neurology (W.C.), Sir Charles Gairdner Hospital, Perth, Australia; the Department of Neurology (T.C.), Massachusetts General Hospital, Boston; the Department of Neurology (J.d.S.), Strasbourg University, France; the Department of Multiple Sclerosis Therapeutics (K.F.), Tohoku University Graduate School of Medicine, Sendai, Japan; the Departments of Neurology and Neurotherapeutics (B.G.), University of Texas Southwestern Medical Center, Dallas; The Walton Centre NHS Trust (A.J.), Liverpool, UK; the Molecular Neuroimmunology Group, Department of Neurology (S.J.), University Hospital Heidelberg, Germany; the Center for Multiple Sclerosis Investigation (M.L.-P.), Federal University of Minas Gerais Medical School, Belo Horizonte, Brazil; the Department of Neurology (M.L.), Johns Hopkins University, Baltimore, MD; Portland VA Medical Center and Oregon Health and Sciences University (J.H.S.), Portland; the Department of Neurology (S.T.), National Pediatric Hospital Dr. Juan P. Garrahan, Buenos Aires, Argentina; the Department of Medicine (A.L.T.), University of British Columbia, Vancouver, Canada; Nuffield Department of Clinical Neurosciences (P.W.), University of Oxford, UK; and the Department of Neurology (B.G.W.), Mayo Clinic, Rochester, MN.

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July 2015

Varicella Zoster Virus in Ischemic Optic Neuropathy.

Ophthalmology 2015 Oct 6;122(10):2142-5. Epub 2015 Jun 6.

Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado.

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October 2015

B lymphocytes in neuromyelitis optica.

Neurol Neuroimmunol Neuroinflamm 2015 Jun 7;2(3):e104. Epub 2015 May 7.

Departments of Neurology and Ophthalmology and Neuroscience Program (J.L.B.), University of Colorado, Denver; Department of Neurology (K.C.O.), Yale University School of Medicine, New Haven, CT; Neuroimmunology Unit (A.B.-O.), Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada; Department of Neurology (S.S.Z., H.-C.v.B.), UCSF School of Medicine, San Francisco, CA; Department of Neurology (B.H.), Technische Universität München, Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; Department of Immunology (T.F.T.), Duke University Medical Center, Durham, NC; Departments of Neurology and Neurotherapeutics (O.S.), University of Texas Southwestern Medical Center, Dallas, TX; Department of Medicine (M.R.Y.), Divisions of Molecular Medicine and Infectious Diseases, University of California, Los Angeles; Harbor-UCLA Medical Center (M.R.Y.), Torrance, CA; Departments of Ophthalmology and Visual Sciences and Internal Medicine (T.J.S.), University of Michigan Medical School, Ann Arbor; and Institute of Neuropathology (C.S.), University Medical Center, Göttingen, Germany.

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June 2015

Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG.

J Biol Chem 2015 May 19;290(19):12123-34. Epub 2015 Mar 19.

From the Departments of Neurology and Ophthalmology and Neuroscience Program, University of Colorado at Denver, Anschutz Medical Campus, Aurora, Colorado 80045,

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May 2015

Prevalence and distribution of VZV in temporal arteries of patients with giant cell arteritis.

Neurology 2015 May 18;84(19):1948-55. Epub 2015 Feb 18.

From the Departments of Neurology (D.G., T.W., N.K., A.H., A.C., A.R., N.B., J.L.B., R.J.C., R.M., M.A.N.), Microbiology (D.G., R.J.C.), Pathology (P.J.B., B.K.), and Ophthalmology (J.L.B., N.M.), University of Colorado School of Medicine, Aurora; Children's Hospital (C.G., J.E.C.), University of Iowa, Iowa City; Arapahoe County Coroner's Office (K.L.-K.), Aurora, CO; Denver Office of the Medical Examiner (D.B.H.), Denver, CO; Department of Pathology (C.G.E.), Johns Hopkins University School of Medicine, Baltimore, MD; A.M. Rywlin Department of Pathology (B.B., R.J.P.), Mount Sinai Medical Center, Miami Beach, FL; Florida International University (B.B., R.J.P.), Miami Beach; Scheie Eye Institute (M.A.T.) and Department of Pathology and Laboratory Medicine (F.F.), University of Pennsylvania, Philadelphia; Texas Oculoplastic Consultants (M.A., E.W., V.D.), Austin; University of Texas, Southwestern - Austin Transitional Year Program (E.W.), Austin; Departments of Pathology and Laboratory Medicine, Ophthalmology, and Visual Sciences (S.R.), University of British Columbia, Vancouver, Canada; Landspitali University Hospital (V.P.), Reykjavik, Iceland; Department of Neurology (L.P.) and Pathological Institute (S.M.), Assaf Harofeh Medical Center, Zerifin, University of Tel Aviv, Israel; Department of Pathology (D.C.), Centre Hospitalier Universitaire du Nord and RECIP, Amiens, France; Institute of Neuropathology (K.K.), University of Duisburg-Essen, Germany; and Department of Neuropathology (W.B.), University Medical Center Gottingen, Germany.

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May 2015

Re-evaluating the treatment of acute optic neuritis.

J Neurol Neurosurg Psychiatry 2015 Jul 29;86(7):799-808. Epub 2014 Oct 29.

Departments of Neurology & Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas, USA Departments of Neurology & Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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July 2015

Evaluation of aquaporin-4 antibody assays.

Clin Exp Neuroimmunol 2014 Oct 22;5(3):290-303. Epub 2014 Apr 22.

Department of Neurology, Mayo Clinic College of Medicine, Scottsdale, AZ, USA.

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October 2014

Treatment of neuromyelitis optica: state-of-the-art and emerging therapies.

Nat Rev Neurol 2014 Sep 12;10(9):493-506. Epub 2014 Aug 12.

Department of Medicine, University of California, San Francisco, Health Science East Tower Room 1246, 513 Parnassus Avenue, San Francisco, CA 94143, USA.

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September 2014

Neuromyelitis optica MOG-IgG causes reversible lesions in mouse brain.

Acta Neuropathol Commun 2014 Mar 31;2:35. Epub 2014 Mar 31.

Academic Neurosurgery Unit, St, George's, University of London, London, UK.

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March 2014

The treatment of neuromyelitis optica.

J Neuroophthalmol 2014 Mar;34(1):70-82

Departments of Neurology (MCK, JLB) and Ophthalmology (JS, JLB), University of Colorado Denver, Denver, Colorado; and Neuroscience Program (MCK, JS, JLB), University of Colorado Denver, Denver, Colorado.

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March 2014

Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G.

J Neuroinflammation 2014 Jan 27;11:16. Epub 2014 Jan 27.

Department of Medicine and Physiology, University of California, 1246 Health Sciences East Tower, San Francisco, CA 94143-0521, USA.

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January 2014

Early loss of oligodendrocytes in human and experimental neuromyelitis optica lesions.

Acta Neuropathol 2014 Apr 30;127(4):523-38. Epub 2013 Nov 30.

Institute of Neuropathology, University Medical Centre Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Germany.

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April 2014

Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica.

Acta Neuropathol 2013 Nov 31;126(5):699-709. Epub 2013 Aug 31.

Departments of Medicine and Physiology, University of California, San Francisco, CA, 94143, USA.

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November 2013

Neuromyelitis optica IgG causes placental inflammation and fetal death.

J Immunol 2013 Sep 9;191(6):2999-3005. Epub 2013 Aug 9.

Academic Neurosurgery Unit, St. George's, University of London, London SW17 0RE, United Kingdom.

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September 2013

Multifocal VZV vasculopathy with temporal artery infection mimics giant cell arteritis.

Neurology 2013 May 1;80(22):2017-21. Epub 2013 May 1.

Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA.

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May 2013

Optic neuritis in neuromyelitis optica.

Prog Retin Eye Res 2013 Sep 30;36:159-71. Epub 2013 Mar 30.

Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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September 2013

Discovery of peptoid ligands for anti-aquaporin 4 antibodies.

Chem Biol 2013 Mar;20(3):351-9

Departments of Chemistry and Cancer Biology, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA.

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March 2013

A small-molecule screen yields idiotype-specific blockers of neuromyelitis optica immunoglobulin G binding to aquaporin-4.

J Biol Chem 2012 Oct 18;287(44):36837-44. Epub 2012 Sep 18.

Department of Medicine, University of California, San Francisco, California 94143-0521, USA.

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October 2012

Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or supramolecular assembly.

Glia 2012 Dec 14;60(12):2027-39. Epub 2012 Sep 14.

Department of Medicine, University of California, San Francisco, California 94143, USA.

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December 2012

Trigger, pathogen, or bystander: the complex nexus linking Epstein- Barr virus and multiple sclerosis.

Mult Scler 2012 Sep 8;18(9):1204-8. Epub 2012 Jun 8.

Department of Neurology, University of Colorado Denver, Aurora, CO 80045, USA.

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September 2012

Neuromyelitis optica IgG and natural killer cells produce NMO lesions in mice without myelin loss.

Acta Neuropathol 2012 Jun 22;123(6):861-72. Epub 2012 Apr 22.

Department of Medicine, University of California, San Francisco, 1246 Health Sciences East Tower, San Francisco, CA 94143-0521, USA.

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June 2012

Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica.

Ann Neurol 2012 Mar 23;71(3):314-22. Epub 2012 Jan 23.

Department of Medicine, University of California, San Francisco, CA 94143-0521, USA.

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March 2012

Dural sinus stent placement for idiopathic intracranial hypertension.

J Neurosurg 2012 Mar 9;116(3):538-48. Epub 2011 Dec 9.

Department of Radiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.

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March 2012

Viruses and multiple sclerosis.

Neuroscientist 2011 Dec;17(6):659-76

Department of Neurology, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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December 2011

Intravenous neuromyelitis optica autoantibody in mice targets aquaporin-4 in peripheral organs and area postrema.

PLoS One 2011 4;6(11):e27412. Epub 2011 Nov 4.

Departments of Medicine and Physiology, University of California San Francisco, San Francisco, California, United States of America.

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March 2012

Evidence against cellular internalization in vivo of NMO-IgG, aquaporin-4, and excitatory amino acid transporter 2 in neuromyelitis optica.

J Biol Chem 2011 Dec 8;286(52):45156-64. Epub 2011 Nov 8.

Department of Medicine and Physiology, University of California, San Francisco, California 94143, USA.

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December 2011

Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms.

Ann Neurol 2011 Dec 8;70(6):943-54. Epub 2011 Nov 8.

Department of Physiology, University of California at San Francisco, San Francisco, CA 94143-0521, USA.

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December 2011

Wolfram Syndrome: a rare optic neuropathy in youth with type 1 diabetes.

Optom Vis Sci 2011 Nov;88(11):E1383-90

The Barbara Davis Center for Childhood Diabetes, Departments of Pediatrics and Ophthalmology, University of Colorado, Denver, Aurora, Colorado 80045, USA.

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November 2011

Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis.

J Neuroimmunol 2011 Sep 26;238(1-2):87-95. Epub 2011 Aug 26.

Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, G12 8TA, UK.

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September 2011

Identification of peptide targets in neuromyelitis optica.

J Neuroimmunol 2011 Jul 28;236(1-2):65-71. Epub 2011 May 28.

Department of Neurology, University of Colorado School of Medicine, 12700 E. 19th Avenue, Box B182, Aurora, CO 80045, United States.

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July 2011

Orthogonal array formation by human aquaporin-4: examination of neuromyelitis optica-associated aquaporin-4 polymorphisms.

J Neuroimmunol 2011 Jul 31;236(1-2):93-8. Epub 2011 May 31.

Department of Medicine, University of California, San Francisco, CA 94143, USA.

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July 2011

Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays.

J Biol Chem 2011 May 21;286(18):16516-24. Epub 2011 Mar 21.

Department of Medicine, University of California, San Francisco, California 94143, USA.

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May 2011

Recent advances in the treatment of multiple sclerosis.

J Exp Pharmacol 2010 2;2:155-61. Epub 2010 Nov 2.

University of Colorado, Aurora, CO, USA.

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May 2016

Live cell analysis of aquaporin-4 m1/m23 interactions and regulated orthogonal array assembly in glial cells.

J Biol Chem 2009 Dec;284(51):35850-60

Departments of Medicine and Physiology, University of California, San Francisco, California 94143, USA.

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December 2009

Analyses of cerebrospinal fluid in the diagnosis and monitoring of multiple sclerosis.

J Neuroimmunol 2010 Feb 25;219(1-2):1-7. Epub 2009 Sep 25.

Department of Neurology, University of Texas Southwestern Medical Center at Dallas, TX, USA.

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February 2010