Publications by authors named "Jeffrey Kopp"

100Publications

COVID-19 Usurps Host Regulatory Networks.

Front Pharmacol 2020 14;11:1278. Epub 2020 Aug 14.

Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fphar.2020.01278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456869PMC
August 2020

APOL1, Acidity, and ATP: Affecting Mitochondrial Function.

Authors:
Jeffrey B Kopp

Am J Nephrol 2020 3;51(9):693-694. Epub 2020 Sep 3.

Kidney Diseases Section, NIDDK, NIH, Bethesda, Maryland, USA,

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http://dx.doi.org/10.1159/000509990DOI Listing
October 2020

APOL1 renal risk variants exacerbate podocyte injury by increasing inflammatory stress.

BMC Nephrol 2020 Aug 27;21(1):371. Epub 2020 Aug 27.

Kidney Disease Section, NIDDK, NIH, KDB, 10 Center Dr, 3N116, Bethesda, MD, 20892-1268, USA.

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http://dx.doi.org/10.1186/s12882-020-01995-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450955PMC
August 2020

CircZNF609 is involved in the pathogenesis of focal segmental glomerulosclerosis by sponging miR-615-5p.

Biochem Biophys Res Commun 2020 Oct 14;531(3):341-349. Epub 2020 Aug 14.

Department of Nephrology, Shengjing Hospital of China Medical University, Shenyang, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.07.066DOI Listing
October 2020

Podocytopathies.

Nat Rev Dis Primers 2020 Aug 13;6(1):68. Epub 2020 Aug 13.

Department of Clinical and Experimental Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.

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http://dx.doi.org/10.1038/s41572-020-0196-7DOI Listing
August 2020

Proteinuria Reduction and Kidney Survival in Focal Segmental Glomerulosclerosis.

Am J Kidney Dis 2020 Aug 10. Epub 2020 Aug 10.

Division of Nephrology, Department of Pediatrics, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1053/j.ajkd.2020.04.014DOI Listing
August 2020

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease.

BMC Nephrol 2020 Jul 13;21(1):270. Epub 2020 Jul 13.

Kidney Disease Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s12882-020-01921-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358194PMC
July 2020

COVID-19-Associated Collapsing Glomerulopathy: An Emerging Entity.

Kidney Int Rep 2020 Jun 4;5(6):759-761. Epub 2020 May 4.

Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.ekir.2020.04.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196556PMC
June 2020

Launching APOLLO: The Role of Genetic Variants in Live- and Deceased-Donor Kidney Transplantation.

Kidney Int Rep 2020 Mar 27;5(3):252-254. Epub 2019 Dec 27.

Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.ekir.2019.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056915PMC
March 2020

Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.

Proc Natl Acad Sci U S A 2020 03 24;117(10):5409-5419. Epub 2020 Feb 24.

Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1916897117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071891PMC
March 2020

miR-150 inhibitor ameliorates adriamycin-induced focal segmental glomerulosclerosis.

Biochem Biophys Res Commun 2020 02 29;522(3):618-625. Epub 2019 Nov 29.

Department of Nephrology, The Affiliated Shengjing Hospital, China Medical University, Shenyang, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.11.096DOI Listing
February 2020

Genetic Testing for Genetic Variants in Clinical Practice: Finally Starting to Arrive.

Clin J Am Soc Nephrol 2020 01 18;15(1):126-128. Epub 2019 Nov 18.

Basic Research Program Frederick National Laboratories for Cancer Research, Frederick, Maryland.

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http://dx.doi.org/10.2215/CJN.01810219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946079PMC
January 2020

Rationale and Design for a Phase 1 Study of -Acetylmannosamine for Primary Glomerular Diseases.

Kidney Int Rep 2019 Oct 25;4(10):1454-1462. Epub 2019 Jun 25.

Kidney Disease Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.ekir.2019.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829193PMC
October 2019

APOL1 Nephropathy Risk Alleles and Mortality in African American Adults: A Cohort Study.

Am J Kidney Dis 2020 01 26;75(1):54-60. Epub 2019 Sep 26.

Basic Research Program, Frederick National Laboratory for Cancer Research, Frederick, MD. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2019.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008402PMC
January 2020

Chronic kidney disease in propionic acidemia.

Genet Med 2019 12 28;21(12):2830-2835. Epub 2019 Jun 28.

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41436-019-0593-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045176PMC
December 2019

Renal Failure Patients in Disasters.

Disaster Med Public Health Prep 2019 08 6;13(4):782-790. Epub 2019 May 6.

National Institute of Diabetes and Digestive and Kidney Diseases, Kidney Diseases Branch, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1017/dmp.2018.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897549PMC
August 2019

Impact of Genetic Variants on HIV-1 Infection and Disease Progression.

Front Immunol 2019 24;10:53. Epub 2019 Jan 24.

Molecular Genetic Epidemiology Section, Basic Science Program, Basic Research Laboratory, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, United States.

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http://dx.doi.org/10.3389/fimmu.2019.00053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353846PMC
December 2019

One Actor, Many Roles: Histopathologies Associated With APOL1 Genetic Variants.

Adv Anat Pathol 2019 May;26(3):215-219

Kidney Diseases Branch, NIDDK, NIH, Bethesda.

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http://dx.doi.org/10.1097/PAP.0000000000000221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458071PMC
May 2019

Expanding the spectrum of APOL1-related renal disease: de novo collapsing glomerulopathy following kidney transplant.

Authors:
Jeffrey B Kopp

Kidney Int 2018 12;94(6):1048-1050

Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274138PMC
December 2018

V260E Is a Frequent Cause of Steroid-Resistant Nephrotic Syndrome in Black South African Children.

Kidney Int Rep 2018 Nov 29;3(6):1354-1362. Epub 2018 Jul 29.

Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, Maryland, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24680249183016
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http://dx.doi.org/10.1016/j.ekir.2018.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224675PMC
November 2018

APOL1-Associated Nephropathy: A Key Contributor to Racial Disparities in CKD.

Am J Kidney Dis 2018 11;72(5 Suppl 1):S8-S16

Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02726386183082
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http://dx.doi.org/10.1053/j.ajkd.2018.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200346PMC
November 2018

APOL1-miR-193 Axis as a Bifunctional Regulator of the Glomerular Parietal Epithelium: Maintaining Parietal Cell Phenotype versus Promoting Podocyte Differentiation.

Am J Pathol 2018 11 8;188(11):2461-2463. Epub 2018 Sep 8.

Kidney Disease Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440183069
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http://dx.doi.org/10.1016/j.ajpath.2018.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207100PMC
November 2018

Genetics, Genomics, and Precision Medicine in End-Stage Kidney Disease.

Semin Nephrol 2018 07;38(4):317-324

Molecular Genetic Epidemiology Section, Center for Cancer Research, National Institutes of Health, Frederick, MD.

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http://dx.doi.org/10.1016/j.semnephrol.2018.05.002DOI Listing
July 2018

Association of APOL1 With Heart Failure With Preserved Ejection Fraction in Postmenopausal African American Women.

JAMA Cardiol 2018 08;3(8):712-720

Molecular Genetic Epidemiology Section, Basic Research Laboratory, Basic Science Program, National Cancer Institute Leidos Biomedical Research, Frederick National Laboratory, Frederick, Maryland.

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http://cardiology.jamanetwork.com/article.aspx?doi=10.1001/j
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http://dx.doi.org/10.1001/jamacardio.2018.1827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143074PMC
August 2018

Kidney Diseases Associated with Human Immunodeficiency Virus Infection.

N Engl J Med 2018 04;378(17):1655-6

National Institutes of Health, Bethesda, MD

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http://dx.doi.org/10.1056/NEJMc1800396DOI Listing
April 2018

Global glomerulosclerosis in primary nephrotic syndrome: including age as a variable to predict renal outcomes.

Authors:
Jeffrey B Kopp

Kidney Int 2018 05;93(5):1043-1044

Kidney Diseases Branch, NIDDK, National Institutes of Health, Bethesda, Maryland, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.01.020DOI Listing
May 2018

Genetic Testing in Clinical Settings.

Am J Kidney Dis 2018 10 11;72(4):569-581. Epub 2018 Apr 11.

Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1053/j.ajkd.2018.02.351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153053PMC
October 2018

Apolipoprotein L1 nephropathies: 2017 in review.

Curr Opin Nephrol Hypertens 2018 05;27(3):153-158

Kidney Disease Section, NIDDK, NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/MNH.0000000000000399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327739PMC
May 2018

ApoL1 renal risk variants induce aberrant THP-1 monocyte differentiation and increase eicosanoid production via enhanced expression of cyclooxygenase-2.

Am J Physiol Renal Physiol 2018 07 10;315(1):F140-F150. Epub 2018 Jan 10.

Kidney Disease Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , Bethesda, Maryland.

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http://dx.doi.org/10.1152/ajprenal.00254.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087794PMC
July 2018

Randomized Clinical Trial Design to Assess Abatacept in Resistant Nephrotic Syndrome.

Kidney Int Rep 2018 Jan 31;3(1):115-121. Epub 2017 Aug 31.

Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, and Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24680249173037
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http://dx.doi.org/10.1016/j.ekir.2017.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762951PMC
January 2018

Risk Variants Independently Associated With Early Cardiovascular Disease Death.

Kidney Int Rep 2018 Jan 24;3(1):89-98. Epub 2017 Aug 24.

Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.ekir.2017.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762961PMC
January 2018

Genotype and Renal Function of Black Living Donors.

J Am Soc Nephrol 2018 04 16;29(4):1309-1316. Epub 2018 Jan 16.

Kidney Disease Branch of National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1681/ASN.2017060658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875947PMC
April 2018

Kidney Diseases Associated with Human Immunodeficiency Virus Infection.

N Engl J Med 2017 12;377(24):2363-2374

From the Division of Renal Diseases and Hypertension, Department of Medicine, George Washington University, Washington, DC (S.D.C., P.L.K.); and the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD (J.B.K., P.L.K.).

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http://dx.doi.org/10.1056/NEJMra1508467DOI Listing
December 2017

APOL1 Renal Risk Variants: Fertile Soil for HIV-Associated Nephropathy.

Semin Nephrol 2017 11;37(6):514-519

Basic Research Laboratory, National Cancer Institute, National Institutes of Health, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD.

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http://dx.doi.org/10.1016/j.semnephrol.2017.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745063PMC
November 2017

HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD.

Sci Rep 2017 10 17;7(1):13362. Epub 2017 Oct 17.

Translational Metabolism Unit, Diabetes Research Center, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41598-017-13835-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645472PMC
October 2017

Chronic Kidney Disease in the Aging Human Immunodeficiency Virus-Infected Population.

Authors:
Jeffrey B Kopp

J Infect Dis 2017 09;216(6):619-621

Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1093/infdis/jix205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853916PMC
September 2017

APOL1 genetic variants are not associated with longitudinal blood pressure in young black adults.

Kidney Int 2017 10 23;92(4):964-971. Epub 2017 May 23.

Kidney Health Research Collaborative, Department of Medicine, University of California, San Francisco, California, USA; San Francisco VA Medical Center, San Francisco, California, USA.

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http://dx.doi.org/10.1016/j.kint.2017.03.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610603PMC
October 2017

Effect of Antiretroviral Therapy on Bone and Renal Health in Young Adults Infected With HIV in Early Life.

J Clin Endocrinol Metab 2017 08;102(8):2896-2904

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Disease, Bethesda, Maryland 20892.

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http://dx.doi.org/10.1210/jc.2017-00197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546869PMC
August 2017

Therapeutics for APOL1 nephropathies: putting out the fire in the podocyte.

Nephrol Dial Transplant 2017 01;32(suppl_1):i65-i70

Kidney Disease Section, NIDDK, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/ndt/gfw402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837624PMC
January 2017

Focal Segmental Glomerulosclerosis.

Clin J Am Soc Nephrol 2017 Mar 27;12(3):502-517. Epub 2017 Feb 27.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland; and

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http://cjasn.asnjournals.org/lookup/doi/10.2215/CJN.05960616
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http://dx.doi.org/10.2215/CJN.05960616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338705PMC
March 2017

Extracellular microRNA signature in chronic kidney disease.

Am J Physiol Renal Physiol 2017 06 11;312(6):F982-F991. Epub 2017 Jan 11.

Division of Renal Diseases and Hypertension, The George Washington University School of Medicine, Washington, District of Columbia;

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http://dx.doi.org/10.1152/ajprenal.00569.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495885PMC
June 2017

Risk Alleles are Associated with More Severe Arteriosclerosis in Renal Resistance Vessels with Aging and Hypertension.

Kidney Int Rep 2016 May 20;1(1):10-23. Epub 2016 Apr 20.

Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1016/j.ekir.2016.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012291PMC
May 2016

Brief Report: APOL1 Renal Risk Variants Are Associated With Chronic Kidney Disease in Children and Youth With Perinatal HIV Infection.

J Acquir Immune Defic Syndr 2016 09;73(1):63-8

*Division of Pediatric Infectious Disease, Department of Pediatrics, Bronx-Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, NY; †Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA; ‡Basic Science Laboratory, Center for Cancer Research, National Cancer Institute, Leidos Biomedical Inc. Frederick National Laboratory, Frederick, MD; §Department of Pediatrics, University of California San Diego (UCSD), La Jolla, CA; ‖Rady Children's Hospital, San Diego, CA; ¶Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD; #Department of Pediatrics, Miller School of Medicine, University of Miami, Miami, FL; **Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA; and ††National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/QAI.0000000000001010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981510PMC
September 2016

Replenishment of the podocyte compartment by parietal epithelial cells.

Authors:
Jeffrey B Kopp

Kidney Int 2015 Nov;88(5):934-5

Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ki.2015.256DOI Listing
November 2015

G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes.

J Am Soc Nephrol 2016 05 30;27(5):1362-78. Epub 2015 Sep 30.

Department of Medicine, Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, Colorado;

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http://dx.doi.org/10.1681/ASN.2014121271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849814PMC
May 2016

New horizons for human pathogenic autoantibodies.

Discov Med 2015 Jul-Aug;20(108):17-25

Kidney Section, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD 20892, USA.

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May 2016

Preparing for Disasters for Patients on Dialysis.

Clin J Am Soc Nephrol 2015 Aug 28;10(8):1316-7. Epub 2015 Jul 28.

Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland

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http://dx.doi.org/10.2215/CJN.07340715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527027PMC
August 2015

APOL1 Kidney Disease Risk Variants: An Evolving Landscape.

Semin Nephrol 2015 May;35(3):222-36

Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1016/j.semnephrol.2015.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562465PMC
May 2015

APOL1 Genotype and Race Differences in Incident Albuminuria and Renal Function Decline.

J Am Soc Nephrol 2016 Mar 15;27(3):887-93. Epub 2015 Jul 15.

Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, Leidos Biomedical Inc., Frederick National Laboratory, Frederick, Maryland.

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http://dx.doi.org/10.1681/ASN.2015020124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769203PMC
March 2016

Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects.

J Am Soc Nephrol 2016 Mar 6;27(3):814-23. Epub 2015 Jul 6.

Division of Nephrology, Department of Internal Medicine and Department of Physiology and Biophysics, Case Western Reserve University and Rammelkamp Center for Education and Research, MetroHealth System, Cleveland, Ohio;

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http://dx.doi.org/10.1681/ASN.2014111131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769193PMC
March 2016

Activation of AMP-activated protein kinase prevents TGF-β1-induced epithelial-mesenchymal transition and myofibroblast activation.

Am J Pathol 2015 Aug 10;185(8):2168-80. Epub 2015 Jun 10.

Department of Medicine, University of Texas Health Science Center, San Antonio, Texas; Audie L. Murphy Memorial Hospital Division, South Texas Veterans Healthcare System, San Antonio, Texas.

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http://dx.doi.org/10.1016/j.ajpath.2015.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530134PMC
August 2015

APOL1 Risk Alleles Are Associated with Exaggerated Age-Related Changes in Glomerular Number and Volume in African-American Adults: An Autopsy Study.

J Am Soc Nephrol 2015 Dec 2;26(12):3179-89. Epub 2015 Jun 2.

Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, Lidos Biomedical Inc., Frederick National Laboratory, Frederick, Maryland.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2014080768
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http://dx.doi.org/10.1681/ASN.2014080768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657832PMC
December 2015

Sequencing rare and common APOL1 coding variants to determine kidney disease risk.

Kidney Int 2015 Oct 20;88(4):754-63. Epub 2015 May 20.

Molecular Genetic Epidemiology Section, Basic Research Laboratory, Basic Science Program, NCI, Leidos Biomedical Research, Frederick National Laboratory, Frederick, Maryland, USA.

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http://dx.doi.org/10.1038/ki.2015.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591109PMC
October 2015

Copy Number Variation at the APOL1 Locus.

PLoS One 2015 1;10(5):e0125410. Epub 2015 May 1.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts, United States of America; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125410PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416782PMC
February 2016

APOL1 toxin, innate immunity, and kidney injury.

Kidney Int 2015 Jul 8;88(1):28-34. Epub 2015 Apr 8.

Molecular Genetic Epidemiology Section, Basic Research Laboratory, Basic Science Program, Center for Cancer Research, NCI, NIH, Leidos Biomedical Research, Frederick National Laboratory, Frederick, Maryland, USA.

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http://dx.doi.org/10.1038/ki.2015.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490079PMC
July 2015

APOL1 Risk Variants Are Strongly Associated with HIV-Associated Nephropathy in Black South Africans.

J Am Soc Nephrol 2015 Nov 18;26(11):2882-90. Epub 2015 Mar 18.

Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Division of Nephrology, University of the Witwatersrand, Johannesburg, South Africa

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http://dx.doi.org/10.1681/ASN.2014050469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625661PMC
November 2015

HIV and chronic kidney disease.

Clin Nephrol 2015 ;83(7 Suppl 1):32-8

Division of Nephrology, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa, and Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.5414/cnp83s032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536633PMC
May 2016

Loss of Krüppel-like factor 6 cripples podocyte mitochondrial function.

Authors:
Jeffrey B Kopp

J Clin Invest 2015 Mar 17;125(3):968-71. Epub 2015 Feb 17.

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http://dx.doi.org/10.1172/JCI80280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362253PMC
March 2015

HIV-associated nephropathies: epidemiology, pathology, mechanisms and treatment.

Nat Rev Nephrol 2015 Mar 17;11(3):150-60. Epub 2015 Feb 17.

Kidney Disease Section, NIDDK, NIH, 10 Center Drive, 3N116 Bethesda, MD 20892-1268, USA.

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http://dx.doi.org/10.1038/nrneph.2015.9DOI Listing
March 2015

Circulating and urinary microRNA profile in focal segmental glomerulosclerosis: a pilot study.

Eur J Clin Invest 2015 Apr;45(4):394-404

Division of Renal Diseases and Hypertension, The George Washington University School of Medicine, Washington, DC, USA.

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http://dx.doi.org/10.1111/eci.12420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4903079PMC
April 2015

Integrated Design of Antibodies for Systems Biology Using

J Proteomics Bioinform 2014 Mar;7(4):088-94

Epithelial Systems Biology Laboratory, National Heart, Lung and Blood Institute, NIH, Bethesda, MD, USA.

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http://omicsonline.org/open-access/integrated-design-of-anti
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http://dx.doi.org/10.4172/jpb.1000307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201049PMC
March 2014

Podocyte injury caused by indoxyl sulfate, a uremic toxin and aryl-hydrocarbon receptor ligand.

PLoS One 2014 22;9(9):e108448. Epub 2014 Sep 22.

Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108448PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171541PMC
December 2015