Jeffrey K Yao

Jeffrey K Yao

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Jeffrey K Yao

Publications by authors named "Jeffrey K Yao"

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Impact of estrogen receptor agonists and model of menopause on enzymes involved in brain metabolism, acetyl-CoA production and cholinergic function.

Life Sci 2020 Jun 19;256:117975. Epub 2020 Jun 19.

University of Pittsburgh, Department of Pharmaceutical Sciences, 1004 Salk Hall, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2020.117975DOI Listing
June 2020

Editorial: Metabolic Disturbances in Mental Illness: Neuropathogenetic Mechanisms and Therapeutic Implications.

Front Neurosci 2020 29;14:21. Epub 2020 Jan 29.

Medical Research Service, VA Pittsburgh Healthcare System, Pittsburgh, PA, United States.

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http://dx.doi.org/10.3389/fnins.2020.00021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000652PMC
January 2020

Estradiol and selective estrogen receptor agonists differentially affect brain monoamines and amino acids levels in transitional and surgical menopausal rat models.

Mol Cell Endocrinol 2019 10 5;496:110533. Epub 2019 Aug 5.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, 15261, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03037207193023
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http://dx.doi.org/10.1016/j.mce.2019.110533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717664PMC
October 2019

Association between increased serum interleukin-6 levels and sustained attention deficits in patients with major depressive disorder.

Psychol Med 2018 11 8;48(15):2508-2514. Epub 2018 Feb 8.

Institute of Mental Health,Suzhou Psychiatric Hospital,The Affiliated Guangji Hospital of Soochow University,Suzhou, Jiangsu,PR China.

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http://dx.doi.org/10.1017/S0033291718000090DOI Listing
November 2018

Comparison of transitional vs surgical menopause on monoamine and amino acid levels in the rat brain.

Mol Cell Endocrinol 2018 11 5;476:139-147. Epub 2018 May 5.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2018.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120792PMC
November 2018

A rapid UPLC-MS/MS assay for eicosanoids in human plasma: Application to evaluate niacin responsivity.

Prostaglandins Leukot Essent Fatty Acids 2018 09 18;136:153-159. Epub 2017 Jan 18.

Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15216, United States; Medical Research Service, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, United States; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States. Electronic address:

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http://dx.doi.org/10.1016/j.plefa.2017.01.003DOI Listing
September 2018

Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases.

Prostaglandins Leukot Essent Fatty Acids 2018 09 10;136:3-13. Epub 2017 Mar 10.

Department of Radiology, Neurology, and Psychological Sciences, and the Thompson Center, William and Nancy Thompson Endowed Chair in Radiology, University of Missouri School of Medicine, Columbia, MO, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S09523278163021
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http://dx.doi.org/10.1016/j.plefa.2017.03.006DOI Listing
September 2018

Pregnenolone-progesterone-allopregnanolone pathway as a potential therapeutic target in first-episode antipsychotic-naïve patients with schizophrenia.

Psychoneuroendocrinology 2018 04 7;90:43-51. Epub 2018 Feb 7.

Medical Research Service, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA; Departments of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15216, USA; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03064530173144
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http://dx.doi.org/10.1016/j.psyneuen.2018.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864547PMC
April 2018

Neurosteroids in Schizophrenia: Pathogenic and Therapeutic Implications.

Front Psychiatry 2018 8;9:73. Epub 2018 Mar 8.

Medical Research Service, VA Pittsburgh Healthcare System, Pittsburgh, PA, United States.

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http://dx.doi.org/10.3389/fpsyt.2018.00073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852066PMC
March 2018

Association of sFlt-1 and worsening psychopathology in relatives at high risk for psychosis: A longitudinal study.

Schizophr Res 2017 05 15;183:75-81. Epub 2016 Nov 15.

Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, United States; Division of Public Psychiatry, Massachusetts Mental Health Center, Boston, MA, United States; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2016.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432401PMC
May 2017

Angiogenic and immune signatures in plasma of young relatives at familial high-risk for psychosis and first-episode patients: A preliminary study.

Schizophr Res 2016 Jan 11;170(1):115-22. Epub 2015 Dec 11.

Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; VA Pittsburgh Healthcare System, Medical Research Service, Pittsburgh, PA, United States; Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735038PMC
January 2016

Long-chain omega-3 fatty acids and optimization of cognitive performance.

Mil Med 2014 Nov;179(11 Suppl):95-105

Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, Sennott Square, 3rd Floor, 210 South Bouquet Street, Pittsburgh, PA 15260.

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http://dx.doi.org/10.7205/MILMED-D-14-00168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734634PMC
November 2014

Oxidative stress and therapeutic implications in psychiatric disorders.

Prog Neuropsychopharmacol Biol Psychiatry 2013 Oct 21;46:197-9. Epub 2013 Mar 21.

Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA; Michael E. DeBakey VA Medical Center, Houston, TX, USA; Psychiatry Research Center, Beijing Hui Long Guan Hospital, Peking University, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2013.03.003DOI Listing
October 2013

Associations between purine metabolites and monoamine neurotransmitters in first-episode psychosis.

Front Cell Neurosci 2013 11;7:90. Epub 2013 Jun 11.

Medical Research Service, VA Pittsburgh Healthcare System Pittsburgh, PA, USA ; Department of Psychiatry, University of Pittsburgh School of Medicine Pittsburgh, PA, USA ; Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy Pittsburgh, PA, USA.

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http://dx.doi.org/10.3389/fncel.2013.00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678099PMC
June 2013

Impaired plasmalogens in patients with schizophrenia.

Psychiatry Res 2012 Aug 16;198(3):347-52. Epub 2012 Apr 16.

Duke University Medical Center, Department of Psychiatry and Behavioral Sciences, DUMC Box 3950 Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.psychres.2012.02.019DOI Listing
August 2012

Plasma total antioxidant status and cognitive impairments in schizophrenia.

Schizophr Res 2012 Aug 1;139(1-3):66-72. Epub 2012 May 1.

Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.schres.2012.04.009DOI Listing
August 2012

Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view.

Antioxid Redox Signal 2011 Oct 21;15(7):2011-35. Epub 2011 Apr 21.

Medical Research Service, VA Pittsburgh Healthcare System,7180 Highland Drive, Pittsburgh, PA 15206, USA.

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http://dx.doi.org/10.1089/ars.2010.3603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159108PMC
October 2011

Oxidative stress in schizophrenia: pathogenetic and therapeutic implications.

Antioxid Redox Signal 2011 Oct 4;15(7):1999-2002. Epub 2011 May 4.

Medical Research Service, VA Pittsburgh Healthcare System,7180 Highland Drive, Pittsburgh, PA 15206, USA.

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http://dx.doi.org/10.1089/ars.2010.3646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159103PMC
October 2011

Long-chain omega-3 fatty acids and blood pressure.

Am J Hypertens 2011 Oct 14;24(10):1121-6. Epub 2011 Jul 14.

Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1038/ajh.2011.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235507PMC
October 2011

Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish.

Hepatology 2011 Aug 2;54(2):452-62. Epub 2011 May 2.

Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, and Childrens Hospital, Pittsburgh, PA 15260, USA.

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http://doi.wiley.com/10.1002/hep.24349
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http://dx.doi.org/10.1002/hep.24349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140628PMC
August 2011

Cognition, dopamine and bioactive lipids in schizophrenia.

Front Biosci (Schol Ed) 2011 Jan 1;3:298-330. Epub 2011 Jan 1.

Department of Psychiatry and Western Psychiatric Institute and Clinic University of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060944PMC
http://dx.doi.org/10.2741/s153DOI Listing
January 2011

Niacin sensitivity and the arachidonic acid pathway in schizophrenia.

Schizophr Res 2010 Sep 24;122(1-3):248-56. Epub 2010 Apr 24.

Behavorial Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.schres.2010.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947210PMC
September 2010

Reduced membrane lipids in the cortex of Alzheimer's disease transgenic mice.

Neurochem Res 2009 Jan 29;34(1):102-8. Epub 2008 Mar 29.

Medical Research Service, VA Pittsburgh Healthcare System, 7180 Highland Drive, Pittsburgh, PA 15206, USA,

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http://dx.doi.org/10.1007/s11064-008-9673-1DOI Listing
January 2009

Semantic memory in schizophrenia: association with cell membrane essential fatty acids.

Schizophr Res 2008 Nov 16;106(1):13-28. Epub 2008 Oct 16.

Western Psychiatric Institute & Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O'Hara Street, Pittsburgh, PA 15213, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S09209964080015
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http://dx.doi.org/10.1016/j.schres.2008.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962952PMC
November 2008

High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism.

Psychosom Med 2007 Dec 8;69(9):932-4. Epub 2007 Nov 8.

Department of Psychology, Allegheny College, 520 North Main Street, Meadville, PA 16335-3902, USA.

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http://dx.doi.org/10.1097/PSY.0b013e31815aaa42DOI Listing
December 2007

Reduced platelet serotonergic responsivity as assessed by dense granule secretion in first-episode psychosis.

Clin Biochem 2007 Sep 24;40(13-14):1081-3. Epub 2007 May 24.

Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.clinbiochem.2007.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064870PMC
September 2007

Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers.

Psychiatry Res 2007 Jul 23;152(1):1-10. Epub 2007 Mar 23.

Cardiovascular Behavioral Medicine Postdoctoral Training Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S016517810600320
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http://dx.doi.org/10.1016/j.psychres.2006.10.006DOI Listing
July 2007

Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adults.

Neurosci Lett 2007 Jun 2;421(3):209-12. Epub 2007 Jun 2.

Department of Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15260, United States.

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http://dx.doi.org/10.1016/j.neulet.2007.04.086DOI Listing
June 2007

Blunted serotonergic responsivity in neuroleptic-naïve patients at first-episode of schizophrenia.

Schizophr Res 2007 Feb 3;90(1-3):81-5. Epub 2007 Jan 3.

Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S092099640600483
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http://dx.doi.org/10.1016/j.schres.2006.11.013DOI Listing
February 2007

Clozapine specifically alters the arachidonic acid pathway in mice lacking apolipoprotein D.

Schizophr Res 2007 Jan 28;89(1-3):147-53. Epub 2006 Sep 28.

Department of Molecular Biology, The Scripps Research Institute, 10550 N. Torrey Pines Rd., MB-10, La Jolla, CA 92037, United States.

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http://dx.doi.org/10.1016/j.schres.2006.08.011DOI Listing
January 2007

Altered glutathione redox state in schizophrenia.

Dis Markers 2006 ;22(1-2):83-93

VA Pittsburgh Healthcare System, 7180 Highland Drive, Pittsburgh, PA 15206, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850558PMC
http://dx.doi.org/10.1155/2006/248387DOI Listing
March 2006

Metabolic investigation in psychiatric disorders.

Mol Neurobiol 2005 ;31(1-3):193-203

VA Pittsburgh Healthcare System, Medical Research Service, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1385/MN:31:1-3:193DOI Listing
January 2006

Increased nitric oxide radicals in postmortem brain from patients with schizophrenia.

Schizophr Bull 2004 ;30(4):923-34

VA Pittsburgh Healthcare System (Bldg. #13), 7180 Highland Drive, Pittsburgh, PA 15206, USA.

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http://dx.doi.org/10.1093/oxfordjournals.schbul.a007142DOI Listing
July 2005

Reduced red blood cell membrane essential polyunsaturated fatty acids in first episode schizophrenia at neuroleptic-naive baseline.

Schizophr Bull 2004 ;30(4):901-11

Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1093/oxfordjournals.schbul.a007140DOI Listing
July 2005

Association of plasma apolipoproteins D with RBC membrane arachidonic acid levels in schizophrenia.

Schizophr Res 2005 Jan;72(2-3):259-66

Neurochemistry and Psychopharmacology Laboratory (Bldg. 13), VA Pittsburgh Healthcare System, 7180 Highland Dr., Pittsburgh, PA 15206, USA.

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http://dx.doi.org/10.1016/j.schres.2004.05.007DOI Listing
January 2005

Determination of multiple redox-active compounds by high-performance liquid chromatography with coulometric multi-electrode array system.

J Chromatogr B Analyt Technol Biomed Life Sci 2004 Oct;810(1):93-100

VA Pittsburgh Healthcare System, 7180 Highland Drive, Pittsburgh, PA 15206, USA.

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http://dx.doi.org/10.1016/j.jchromb.2004.07.021DOI Listing
October 2004

Effects of omega-3 fatty acid on platelet serotonin responsivity in patients with schizophrenia.

Prostaglandins Leukot Essent Fatty Acids 2004 Sep;71(3):171-6

VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.plefa.2004.03.011DOI Listing
September 2004

Membrane phospholipids and cytokine interaction in schizophrenia.

Int Rev Neurobiol 2004 ;59:297-326

VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania 15206, USA.

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http://dx.doi.org/10.1016/S0074-7742(04)59012-8DOI Listing
May 2004

Environmental factors and membrane polyunsaturated fatty acids in schizophrenia.

Prostaglandins Leukot Essent Fatty Acids 2003 Dec;69(6):385-91

Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.plefa.2003.08.009DOI Listing
December 2003

Reduced plasma antioxidants in first-episode patients with schizophrenia.

Schizophr Res 2003 Aug;62(3):205-12

Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/s0920-9964(02)00407-3DOI Listing
August 2003

Correlations between peripheral polyunsaturated fatty acid content and in vivo membrane phospholipid metabolites.

Biol Psychiatry 2002 Oct;52(8):823-30

Neurochemistry and Psychopharmacology Laboratory, VA Pittsburgh Healthcare System, Building 13, 7180 Highland Drive, Pittsburgh, PA 15206, USA.

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http://dx.doi.org/10.1016/s0006-3223(02)01397-5DOI Listing
October 2002

Does adverse family environment or sex matter in the salivary cortisol responses to anticipatory stress?

Psychiatry Res 2002 Oct;112(2):121-31

University of Delaware, Department of Nursing, Room 361, McDowell Hall, Newark 19716, USA.

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http://dx.doi.org/10.1016/s0165-1781(02)00182-8DOI Listing
October 2002

Membrane pathology in schizophrenia: implication for arachidonic acid signaling.

ScientificWorldJournal 2002 Jul 10;2:1922-36. Epub 2002 Jul 10.

VA Pittsburgh Healthcare System, 7180 Highland Drive, Pittsburgh, PA 15206, USA.

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http://dx.doi.org/10.1100/tsw.2002.870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009427PMC
July 2002