Jeffrey J Fredberg

Jeffrey J Fredberg

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Jeffrey J Fredberg

Publications by authors named "Jeffrey J Fredberg"

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Mechanical signaling in a pulmonary microvascular endothelial cell monolayer.

Biochem Biophys Res Commun 2019 Nov 9;519(2):337-343. Epub 2019 Sep 9.

Center for Lung Biology, College of Medicine, University of South Alabama, Mobile, AL, USA; William B. Burnsed, Jr. Department of Mechanical Engineering, College of Engineering, University of South Alabama, Mobile, AL, USA; Department of Pharmacology, College of Medicine, University of South Alabama, Mobile, AL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.08.169DOI Listing
November 2019

Anti-fibrotic effects of tannic acid through regulation of a sustained TGF-beta receptor signaling.

Respir Res 2019 Jul 29;20(1):168. Epub 2019 Jul 29.

Department of Medicine, Section of Pulmonary and Critical Care Medicine, the University of Chicago, 5841 S. Maryland Ave, MC6076, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1186/s12931-019-1141-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664561PMC
July 2019

Traction microscopy with integrated microfluidics: responses of the multi-cellular island to gradients of HGF.

Lab Chip 2019 04;19(9):1579-1588

Department of Biomedical Sciences, College of Medicine, Korea University, Seoul 02841, Republic of Korea.

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http://dx.doi.org/10.1039/c9lc00173eDOI Listing
April 2019

Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness.

Biophys J 2019 02 7;116(3):518-529. Epub 2019 Jan 7.

Department of Biomedical Engineering, Northwestern University, Evanston, Illinois; Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Department of Mechanical Engineering, Northwestern University, Evanston, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2018.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369565PMC
February 2019

Contact guidance and collective migration in the advancing epithelial monolayer.

Connect Tissue Res 2018 07 17;59(4):309-315. Epub 2017 Oct 17.

a Department of Environmental Health, Harvard T.H. Chan School of Public Health , Boston , MA USA.

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http://dx.doi.org/10.1080/03008207.2017.1384471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867268PMC
July 2018

Transient stretch induces cytoskeletal fluidization through the severing action of cofilin.

Am J Physiol Lung Cell Mol Physiol 2018 05 18;314(5):L799-L807. Epub 2018 Jan 18.

Department of Environmental Health, Harvard T. H. Chan School of Public Health , Boston, Massachusetts.

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http://dx.doi.org/10.1152/ajplung.00326.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008132PMC
May 2018

Scaling Physiologic Function from Cell to Tissue in Asthma, Cancer, and Development.

Ann Am Thorac Soc 2018 02;15(Suppl 1):S35-S37

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1513/AnnalsATS.201710-790KVDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946502PMC
February 2018

Long-range stress transmission guides endothelial gap formation.

Biochem Biophys Res Commun 2018 01 11;495(1):749-754. Epub 2017 Nov 11.

Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.bbrc.2017.11.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761675PMC
January 2018

Long-lived force patterns and deformation waves at repulsive epithelial boundaries.

Nat Mater 2017 10 11;16(10):1029-1037. Epub 2017 Sep 11.

Institute for Bioengineering of Catalonia, The Barcelona Institute of Science and Technology, Barcelona 08028, Spain.

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http://dx.doi.org/10.1038/nmat4972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657559PMC
October 2017

Contribution of rostral fluid shift to intrathoracic airway narrowing in asthma.

J Appl Physiol (1985) 2017 Apr 12;122(4):809-816. Epub 2017 Jan 12.

Toronto Rehabilitation Institute-University Health Network, Toronto, Ontario, Canada;

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http://www.physiology.org/doi/10.1152/japplphysiol.00969.201
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http://dx.doi.org/10.1152/japplphysiol.00969.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504396PMC
April 2017

Homogenizing cellular tension by hepatocyte growth factor in expanding epithelial monolayer.

Sci Rep 2017 04 4;8:45844. Epub 2017 Apr 4.

Department of Biomedical Sciences, College of Medicine, Korea University, Seoul 02841, Korea.

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http://dx.doi.org/10.1038/srep45844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379206PMC
April 2017

Non-equilibrium cytoquake dynamics in cytoskeletal remodeling and stabilization.

Soft Matter 2016 Oct;12(41):8506-8511

Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA and Department Medicine, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1039/c6sm01041eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123702PMC
October 2016

Collective migration and cell jamming in asthma, cancer and development.

J Cell Sci 2016 09 22;129(18):3375-83. Epub 2016 Aug 22.

Harvard T.H. Chan School of Public Health, Department of Environmental Health, Boston, MA 02115, USA Brigham and Women's Hospital, Harvard Medical School, Department of Medicine, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047682PMC
http://dx.doi.org/10.1242/jcs.187922DOI Listing
September 2016

Smooth muscle in human bronchi is disposed to resist airway distension.

Respir Physiol Neurobiol 2016 07 16;229:51-8. Epub 2016 Apr 16.

Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Université Laval, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.resp.2016.04.005DOI Listing
July 2016

Cellular Contraction and Polarization Drive Collective Cellular Motion.

Biophys J 2016 Jun;110(12):2729-2738

Department of Physics and Syracuse Biomaterials Institute, Syracuse University, Syracuse, New York. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2016.05.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919426PMC
June 2016

Problems in biology with many scales of length: Cell-cell adhesion and cell jamming in collective cellular migration.

Exp Cell Res 2016 04 3;343(1):54-59. Epub 2015 Nov 3.

Harvard T. H. Chan School of Public Health, Boston, MA, United States.

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http://dx.doi.org/10.1016/j.yexcr.2015.10.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851584PMC
April 2016

Cell Jamming in the Airway Epithelium.

Ann Am Thorac Soc 2016 Mar;13 Suppl 1:S64-7

1 Harvard T. H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1513/AnnalsATS.201507-476MGDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015735PMC
March 2016

Hidden in the mist no more: physical force in cell biology.

Nat Methods 2016 Feb;13(2):124-5

Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nmeth.3744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861038PMC
February 2016

And I hope you like jamming too.

New J Phys 2015 Sep 14;17(9). Epub 2015 Sep 14.

Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1088/1367-2630/17/9/091001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006935PMC
September 2015

Putting the Squeeze on Airway Epithelia.

Physiology (Bethesda) 2015 Jul;30(4):293-303

Harvard T. H. Chan School of Public Health, Boston, Massachussetts

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http://dx.doi.org/10.1152/physiol.00004.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888965PMC
July 2015

Fluid shear, intercellular stress, and endothelial cell alignment.

Am J Physiol Cell Physiol 2015 Apr 4;308(8):C657-64. Epub 2015 Feb 4.

T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts;

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http://dx.doi.org/10.1152/ajpcell.00363.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398851PMC
April 2015

Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction.

Prog Retin Eye Res 2015 Jan 16;44:86-98. Epub 2014 Sep 16.

Department of Biomedical Engineering, Northwestern University, Evanston, IL, US; Department of Mechanical Engineering, Northwestern University, Evanston, IL, USA; Department of Ophthalmology Engineering, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.preteyeres.2014.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268318PMC
January 2015

Glass-like dynamics in the cell and in cellular collectives.

Wiley Interdiscip Rev Syst Biol Med 2014 Mar-Apr;6(2):137-49. Epub 2014 Jan 15.

School of Public Health, Harvard University, Boston, MA, USA.

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http://dx.doi.org/10.1002/wsbm.1258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000035PMC
October 2014

Comment on "Intracellular stresses in patterned cell assemblies" by M. Moussus et al., Soft Matter, 2014, 10, 2414.

Soft Matter 2014 Oct 4;10(39):7681-2. Epub 2014 Sep 4.

Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1039/c4sm00597jDOI Listing
October 2014

Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma.

Proc Natl Acad Sci U S A 2014 Sep 8;111(38):13876-81. Epub 2014 Sep 8.

Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208; Departments of Mechanical Engineering and Ophthalmology, Northwestern University, Evanston, IL 60208

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http://dx.doi.org/10.1073/pnas.1410602111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183270PMC
September 2014

Hypercompliant apical membranes of bladder umbrella cells.

Biophys J 2014 Sep;107(6):1273-9

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.bpj.2014.07.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167298PMC
September 2014

Power steering, power brakes, and jamming: evolution of collective cell-cell interactions.

Physiology (Bethesda) 2014 Jul;29(4):218-9

Harvard School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1152/physiol.00026.2014DOI Listing
July 2014

Glassy dynamics, cell mechanics, and endothelial permeability.

J Phys Chem B 2013 Oct 30;117(42):12850-6. Epub 2013 May 30.

Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital , Boston, Massachusetts.

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http://dx.doi.org/10.1021/jp4020965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808527PMC
October 2013

Collective migration and cell jamming.

Differentiation 2013 Oct 21;86(3):121-5. Epub 2013 Jun 21.

School of Public Health, Harvard University, Boston, MA 02115, United States.

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http://dx.doi.org/10.1016/j.diff.2013.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795803PMC
October 2013

Illuminating human health through cell mechanics.

Swiss Med Wkly 2013 14;143:w13766. Epub 2013 Mar 14.

Program in Molecular and Integrative Physiological Sciences School of Public Health, Harvard University, Boston, Massachusetts, USA.

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http://dx.doi.org/10.4414/smw.2013.13766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888799PMC
September 2013

Cytoskeletal stiffness, friction, and fluidity of cancer cell lines with different metastatic potential.

Clin Exp Metastasis 2013 Mar 8;30(3):237-50. Epub 2012 Sep 8.

Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA, 02115, USA.

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http://link.springer.com/10.1007/s10585-012-9531-z
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http://dx.doi.org/10.1007/s10585-012-9531-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871859PMC
March 2013

Cell elasticity determines macrophage function.

PLoS One 2012 18;7(9):e41024. Epub 2012 Sep 18.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041024PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445606PMC
March 2013

Dilatation of the constricted human airway by tidal expansion of lung parenchyma.

Am J Respir Crit Care Med 2012 Aug 7;186(3):225-32. Epub 2012 Jun 7.

Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1164/rccm.201202-0368OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423451PMC
August 2012

Low intensity ultrasound perturbs cytoskeleton dynamics.

Soft Matter 2012 Feb;8(8):2438-2443

Faculty of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa, Israel ; Program in Molecular and Integrative Physiological Sciences, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1039/C2SM07246GDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641826PMC
February 2012

In bronchospasm, fluctuations come to life.

Am J Respir Crit Care Med 2011 Dec;184(12):1321-2

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http://dx.doi.org/10.1164/rccm.201106-1002EDDOI Listing
December 2011

Plithotaxis and emergent dynamics in collective cellular migration.

Trends Cell Biol 2011 Nov 23;21(11):638-46. Epub 2011 Jul 23.

Institute for Bioengineering of Catalonia, Ciber Enfermedades Respiratorias, University of Barcelona, Spain.

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http://dx.doi.org/10.1016/j.tcb.2011.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202659PMC
November 2011

Collective cell guidance by cooperative intercellular forces.

Nat Mater 2011 Jun;10(6):469-75

Program in Molecular and Integrative Physiological Sciences, School of Public Health, Harvard University, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nmat3025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135682PMC
June 2011

Dynamics of the cytoskeleton: how much does water matter?

Phys Rev E Stat Nonlin Soft Matter Phys 2011 Jun 27;83(6 Pt 1):061918. Epub 2011 Jun 27.

School of Public Health, Harvard University, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879600PMC
http://dx.doi.org/10.1103/PhysRevE.83.061918DOI Listing
June 2011

Emergence of airway smooth muscle functions related to structural malleability.

J Appl Physiol (1985) 2011 Apr 2;110(4):1130-5. Epub 2010 Dec 2.

Department of Pathology, James Hogg Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/japplphysiol.01192.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075132PMC
April 2011

Glass-like dynamics of collective cell migration.

Proc Natl Acad Sci U S A 2011 Mar 14;108(12):4714-9. Epub 2011 Feb 14.

Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611, USA.

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http://weitzlab.seas.harvard.edu/files/weitzlab/files/2011_p
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http://www.pnas.org/cgi/doi/10.1073/pnas.1010059108
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http://dx.doi.org/10.1073/pnas.1010059108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064326PMC
March 2011

A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged high-throughput biophysical screening.

Respir Res 2011 Jan 13;12. Epub 2011 Jan 13.

Division of Physiology, Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1186/1465-9921-12-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034681PMC
January 2011

Mechanosensing of substrate thickness.

Phys Rev E Stat Nonlin Soft Matter Phys 2010 Oct 22;82(4 Pt 1):041918. Epub 2010 Oct 22.

Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641827PMC
http://dx.doi.org/10.1103/PhysRevE.82.041918DOI Listing
October 2010

Remodeling of integrated contractile tissues and its dependence on strain-rate amplitude.

Phys Rev Lett 2010 Oct 4;105(15):158102. Epub 2010 Oct 4.

School of Public Health, Harvard University, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940190PMC
http://dx.doi.org/10.1103/PhysRevLett.105.158102DOI Listing
October 2010

Stretch magnitude and frequency-dependent actin cytoskeleton remodeling in alveolar epithelia.

Am J Physiol Cell Physiol 2010 Aug 2;299(2):C345-53. Epub 2010 Jun 2.

Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania19104-6321, USA.

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http://dx.doi.org/10.1152/ajpcell.00379.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928639PMC
August 2010

Fluidization and resolidification of the human bladder smooth muscle cell in response to transient stretch.

PLoS One 2010 Aug 6;5(8):e12035. Epub 2010 Aug 6.

Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering College, Chongqing University, Chongqing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012035PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917357PMC
August 2010

Mapping the cytoskeletal prestress.

Am J Physiol Cell Physiol 2010 May 17;298(5):C1245-52. Epub 2010 Feb 17.

Dept. of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpcell.00417.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116352PMC
May 2010

Cell migration driven by cooperative substrate deformation patterns.

Phys Rev Lett 2010 Apr 23;104(16):168104. Epub 2010 Apr 23.

School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947506PMC
http://dx.doi.org/10.1103/PhysRevLett.104.168104DOI Listing
April 2010

Cell stiffness, contractile stress and the role of extracellular matrix.

Biochem Biophys Res Commun 2009 May 25;382(4):697-703. Epub 2009 Mar 25.

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.bbrc.2009.03.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956180PMC
May 2009

Disrupting actin-myosin-actin connectivity in airway smooth muscle as a treatment for asthma?

Proc Am Thorac Soc 2009 May;6(3):295-300

Department of Medicine, University of Chicago, MC6026, 5841 S. Maryland Ave., Chicago, IL 60637, USA.

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http://dx.doi.org/10.1513/pats.200808-078RMDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677405PMC
May 2009

Modulation of host cell mechanics by Trypanosoma cruzi.

J Cell Physiol 2009 Feb;218(2):315-22

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/jcp.21606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592505PMC
February 2009

Febrile temperature leads to significant stiffening of Plasmodium falciparum parasitized erythrocytes.

Am J Physiol Cell Physiol 2009 Jan 2;296(1):C59-64. Epub 2008 Jul 2.

Department of Environmental Health, Program in Molecular and Integrative Physiological Sciences, Harvard School of Public Health, 665 Huntington Ave., Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpcell.00105.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636996PMC
January 2009

Mechanism of inspiratory and expiratory crackles.

Chest 2009 Jan 8;135(1):156-164. Epub 2008 Aug 8.

Brigham and Women's/Faulkner Hospitals, Boston University, and Harvard School of Public Health, Boston, MA.

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http://dx.doi.org/10.1378/chest.07-1562DOI Listing
January 2009

Airway smooth muscle and bronchospasm: fluctuating, fluidizing, freezing.

Respir Physiol Neurobiol 2008 Nov 20;163(1-3):17-24. Epub 2008 Apr 20.

Program in Molecular and Integrative Physiological Sciences, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, United States.

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http://dx.doi.org/10.1016/j.resp.2008.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2591927PMC
November 2008

Being uncomfortable.

J Appl Physiol (1985) 2008 06;104(6):1848-9; author reply 1851

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http://dx.doi.org/10.1152/japplphysiol.zdg-7945-vpcomm.2008DOI Listing
June 2008

Strange dynamics of a dynamic cytoskeleton.

Proc Am Thorac Soc 2008 Jan;5(1):58-61

Program in Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Room 1-313, 665 Huntington Avenue, Boston, MA 02115, USA.

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http://pats.atsjournals.org/cgi/doi/10.1513/pats.200705-055V
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http://dx.doi.org/10.1513/pats.200705-055VSDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645303PMC
January 2008

Out-of-equilibrium dynamics in the cytoskeleton of the living cell.

Phys Rev E Stat Nonlin Soft Matter Phys 2007 Oct 1;76(4 Pt 1):041901. Epub 2007 Oct 1.

Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1103/PhysRevE.76.041901DOI Listing
October 2007

Airway hyperresponsiveness, remodeling, and smooth muscle mass: right answer, wrong reason?

Am J Respir Cell Mol Biol 2007 Sep 26;37(3):264-72. Epub 2007 Apr 26.

Physiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1165/rcmb.2006-0418OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994228PMC
September 2007

Directional memory and caged dynamics in cytoskeletal remodelling.

Biochem Biophys Res Commun 2007 Sep 5;360(4):797-801. Epub 2007 Jul 5.

Molecular and Integrative Physiological Sciences, Department of Environmental Health, School of Public Health, Harvard University, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbrc.2007.05.228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394503PMC
September 2007

Airway smooth muscle proliferation and mechanics: effects of AMP kinase agonists.

Mol Cell Biomech 2007 Sep;4(3):143-57

Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA.

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September 2007

Viscoelasticity of the human red blood cell.

Am J Physiol Cell Physiol 2007 Aug 11;293(2):C597-605. Epub 2007 Apr 11.

Program in Molecular and Integrative Physiological Sciences (MIPS Dept of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpcell.00562.2006DOI Listing
August 2007

Biophysical basis for airway hyperresponsiveness.

Can J Physiol Pharmacol 2007 Jul;85(7):700-14

Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Room E-7616, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1139/Y07-059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901798PMC
July 2007

Cytoskeleton dynamics: fluctuations within the network.

Biochem Biophys Res Commun 2007 Apr 9;355(2):324-30. Epub 2007 Feb 9.

Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbrc.2007.01.191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430849PMC
April 2007

Counterpoint: airway smooth muscle is not useful.

J Appl Physiol (1985) 2007 Apr;102(4):1709-10; discussion 1710-1

Harvard University Cambridge, Massachusetts, USA.

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http://www.physiology.org/doi/10.1152/japplphysiol.01419a.20
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April 2007

Mechanotransduction, asthma, and airway smooth muscle.

Drug Discov Today Dis Models 2007 ;4(3):131-137

Department of Physics, University of Erlangen-Nuremberg, Germany, and Department of Environmental Health, Harvard School of Public Health, Boston, MA.

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https://linkinghub.elsevier.com/retrieve/pii/S17406757070003
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http://dx.doi.org/10.1016/j.ddmod.2007.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390927PMC
January 2007

Deformability, dynamics, and remodeling of cytoskeleton of the adherent living cell.

Biorheology 2006 ;43(1):1-30

Physiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA.

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November 2006

Fast and slow dynamics of the cytoskeleton.

Nat Mater 2006 Aug 9;5(8):636-40. Epub 2006 Jul 9.

Program in Molecular and Integrative Physiological Sciences, Harvard School of Public Health, Boston, Massachusetts 20115, USA.

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http://dx.doi.org/10.1038/nmat1685DOI Listing
August 2006

Tidal breathing pattern differentially antagonizes bronchoconstriction in C57BL/6J vs. A/J mice.

J Appl Physiol (1985) 2006 Jul 16;101(1):249-55. Epub 2006 Feb 16.

Section of Pulmonary and Critical Care Medicine, University of Chicago, 5841 S. Maryland Ave., MC6026, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1152/japplphysiol.01010.2004DOI Listing
July 2006

Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness?

Am J Respir Cell Mol Biol 2006 Jul 16;35(1):55-64. Epub 2006 Feb 16.

Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1165/rcmb.2005-0453OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553364PMC
July 2006

Effect of stretch on structural integrity and micromechanics of human alveolar epithelial cell monolayers exposed to thrombin.

Am J Physiol Lung Cell Mol Physiol 2006 Jun 6;290(6):L1104-10. Epub 2006 Jan 6.

Unitat de Biofísica i Bioenginyeria, Facultat de Medicina, Casanova 143, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1152/ajplung.00436.2005DOI Listing
June 2006

Stress transmission in the lung: pathways from organ to molecule.

Annu Rev Physiol 2006 ;68:507-41

Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.physiol.68.
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http://dx.doi.org/10.1146/annurev.physiol.68.072304.114110DOI Listing
June 2006

Filamin-a and rheological properties of cultured melanoma cells.

Biophys J 2006 Mar 30;90(6):2199-205. Epub 2005 Dec 30.

Physiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1529/biophysj.105.061267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386798PMC
March 2006

Smooth muscle length adaptation and actin filament length: a network model of the cytoskeletal dysregulation.

Can J Physiol Pharmacol 2005 Oct;83(10):923-31

Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1139/y05-092DOI Listing
October 2005