Jeffrey G McDonald

Jeffrey G McDonald

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Jeffrey G McDonald

Jeffrey G McDonald

Publications by authors named "Jeffrey G McDonald"

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Uptake of HDL-cholesterol contributes to lipid accumulation in clear cell renal cell carcinoma.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 Dec 9;1864(12):158525. Epub 2019 Sep 9.

Department of Molecular Genetics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2019.158525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832851PMC
December 2019

Insights into lipid accumulation in skeletal muscle in dysferlin-deficient mice.

J Lipid Res 2019 Dec 25;60(12):2057-2073. Epub 2019 Oct 25.

Division of Nutrition and Metabolic Diseases Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390.

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http://dx.doi.org/10.1194/jlr.RA119000399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889719PMC
December 2019

Biliopancreatic Diversion Induces Greater Metabolic Improvement Than Roux-en-Y Gastric Bypass.

Cell Metab 2019 Nov 3;30(5):855-864.e3. Epub 2019 Oct 3.

Center for Human Nutrition, Washington University School of Medicine, St. Louis, MO, USA; Departments of Medicine and Pharmacology, University of California, San Diego, San Diego, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876863PMC
November 2019

Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition.

Nat Commun 2019 06 5;10(1):2452. Epub 2019 Jun 5.

Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1038/s41467-019-10279-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549186PMC
June 2019

Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans.

Cell Rep 2019 Apr;27(5):1376-1386.e6

Children's Medical Center Research Institute, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Eugene McDermott Center for Human Growth and Development, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.04.005DOI Listing
April 2019

Three-phase liquid extraction: a simple and fast method for lipidomic workflows.

J Lipid Res 2019 Mar 4;60(3):694-706. Epub 2019 Jan 4.

Center for Human Nutrition University of Texas Southwestern Medical Center, Dallas, TX 75390

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http://www.jlr.org/lookup/doi/10.1194/jlr.D090795
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http://dx.doi.org/10.1194/jlr.D090795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399505PMC
March 2019

Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice.

Elife 2019 02 20;8. Epub 2019 Feb 20.

Departments of Molecular Genetics, Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, United States.

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http://dx.doi.org/10.7554/eLife.44396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402834PMC
February 2019

Cilia-Associated Oxysterols Activate Smoothened.

Mol Cell 2018 10;72(2):316-327.e5

Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765183069
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http://dx.doi.org/10.1016/j.molcel.2018.08.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503851PMC
October 2018

Low-density lipoprotein docosahexaenoic acid nanoparticles induce ferroptotic cell death in hepatocellular carcinoma.

Free Radic Biol Med 2017 11 8;112:597-607. Epub 2017 Sep 8.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA; Internal Medicine Division of Liver and Digestive Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848495PMC
November 2017

Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation.

Cell 2017 Nov 12;171(5):1057-1071.e11. Epub 2017 Oct 12.

Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143-0795, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693620PMC
November 2017

Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine.

J Lipid Res 2017 10 19;58(10):1988-1998. Epub 2017 Jun 19.

Departments of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046

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http://dx.doi.org/10.1194/jlr.M077610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625122PMC
October 2017

Distinct oxysterol requirements for positioning naïve and activated dendritic cells in the spleen.

Sci Immunol 2017 Apr;2(10)

Department of Microbiology and Immunology and Howard Hughes Medical Institute, University of California San Francisco, San Francisco, CA 94143, USA.

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http://immunology.sciencemag.org/lookup/doi/10.1126/sciimmun
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http://dx.doi.org/10.1126/sciimmunol.aal5237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646419PMC
April 2017

Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways.

Elife 2015 Jun 26;4:e07999. Epub 2015 Jun 26.

Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, United States.

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https://elifesciences.org/articles/07999
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http://dx.doi.org/10.7554/eLife.07999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501332PMC
June 2015

Bazedoxifene and conjugated estrogen prevent diet-induced obesity, hepatic steatosis, and type 2 diabetes in mice without impacting the reproductive tract.

Am J Physiol Endocrinol Metab 2014 Aug 17;307(3):E345-54. Epub 2014 Jun 17.

Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas; and

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http://dx.doi.org/10.1152/ajpendo.00653.2013DOI Listing
August 2014

Inflammation. 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon.

Science 2014 Aug;345(6197):679-84

Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1126/science.1254790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289637PMC
August 2014

Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer.

Proc Natl Acad Sci U S A 2014 Mar 3;111(10):3865-70. Epub 2014 Feb 3.

Sir John Walsh Research Institute, Department of Oral Sciences, Faculty of Dentistry, and School of Pharmacy, University of Otago, Dunedin 9054, New Zealand.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1324245111
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http://dx.doi.org/10.1073/pnas.1324245111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956205PMC
March 2014

27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.

Cell Rep 2013 Nov 7;5(3):637-45. Epub 2013 Nov 7.

Department of Pediatrics, Division of Pulmonary and Vascular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.celrep.2013.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950897PMC
November 2013

Lipidomics technologies at the end of the first decade and the beginning of the next.

Adv Nutr 2013 Sep 1;4(5):565-7. Epub 2013 Sep 1.

Georgia Institute of Technology, Atlanta, GA.

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http://dx.doi.org/10.3945/an.113.004333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771151PMC
September 2013

A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma.

J Lipid Res 2012 Jul 19;53(7):1399-409. Epub 2012 Apr 19.

Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1194/jlr.D022285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371252PMC
July 2012

Steroid profiling by gas chromatography-mass spectrometry and high performance liquid chromatography-mass spectrometry for adrenal diseases.

Horm Cancer 2011 Dec;2(6):324-32

Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1007/s12672-011-0099-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437926PMC
December 2011

CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions.

J Biol Chem 2009 Oct 16;284(42):28485-9. Epub 2009 Aug 16.

Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9046, USA.

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http://dx.doi.org/10.1074/jbc.R109.042168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781391PMC
October 2009

Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling.

Cancer Res 2009 Oct 13;69(20):7986-93. Epub 2009 Oct 13.

Department of Pediatrics, McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center at Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764330PMC
October 2009

25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production.

Proc Natl Acad Sci U S A 2009 Sep 15;106(39):16764-9. Epub 2009 Sep 15.

Department of Molecular Genetics and The Cancer Immunobiology Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1073/pnas.0909142106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757821PMC
September 2009

Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance.

Cell Metab 2008 Dec;8(6):512-21

Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046, USA.

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http://dx.doi.org/10.1016/j.cmet.2008.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652870PMC
December 2008

Identification and quantitation of sorbitol-based nuclear clarifying agents extracted from common laboratory and consumer plasticware made of polypropylene.

Anal Chem 2008 Jul 6;80(14):5532-41. Epub 2008 Jun 6.

Department of Molecular Genetics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1021/ac8005632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727714PMC
July 2008

Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry.

Methods Enzymol 2007 ;432:145-70

Department of Molecular Genetics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S007668790732006
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http://dx.doi.org/10.1016/S0076-6879(07)32006-5DOI Listing
March 2008

Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs.

J Biol Chem 2007 Sep 16;282(37):27436-46. Epub 2007 Jul 16.

Departments of Molecular Genetics and Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M704976200
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http://dx.doi.org/10.1074/jbc.M704976200DOI Listing
September 2007

Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands.

J Biol Chem 2006 Sep 20;281(38):27816-26. Epub 2006 Jul 20.

Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, 75390, USA.

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http://dx.doi.org/10.1074/jbc.M603781200DOI Listing
September 2006

Liver X receptors regulate adrenal cholesterol balance.

J Clin Invest 2006 Jul;116(7):1902-12

Department of Pharmacology and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9050, USA.

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http://dx.doi.org/10.1172/JCI28400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1483175PMC
July 2006

Radial dilution model for the distribution of toxaphene in the United States and Canada on the basis of measured concentrations in tree bark.

Environ Sci Technol 2003 Feb;37(3):475-81

School of Public and Environmental Affairs and Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.

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http://dx.doi.org/10.1021/es020707gDOI Listing
February 2003