Jeffrey D Lifson

Jeffrey D Lifson

UNVERIFIED PROFILE

Are you Jeffrey D Lifson?   Register this Author

Register author
Jeffrey D Lifson

Jeffrey D Lifson

Publications by authors named "Jeffrey D Lifson"

Are you Jeffrey D Lifson?   Register this Author

100Publications

3198Reads

14Profile Views

Blocking αβ integrin binding to SIV does not improve virologic control.

Science 2019 09;365(6457):1033-1036

Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aaw7765DOI Listing
September 2019

Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans.

PLoS Pathog 2019 Jul 10;15(7):e1007869. Epub 2019 Jul 10.

HIV Dynamics and Replication Program, National Cancer Institute Frederick, National Institutes of Health, Frederick, MD, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1007869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619828PMC
July 2019

Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy.

Curr Top Microbiol Immunol 2018;417:69-109

AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/82_2017_73DOI Listing
June 2019

Short Communication: Ultrasensitive Immunoassay for Assessing Residual Simian-Tropic HIV in Nonhuman Primate Models of AIDS.

AIDS Res Hum Retroviruses 2019 May 13;35(5):473-476. Epub 2019 Feb 13.

1 AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland.

View Article

Download full-text PDF

Source
https://www.liebertpub.com/doi/10.1089/AID.2018.0278
Publisher Site
http://dx.doi.org/10.1089/AID.2018.0278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6508063PMC
May 2019

Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo.

Retrovirology 2019 04 4;16(1):11. Epub 2019 Apr 4.

AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12977-019-0473-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450007PMC
April 2019

Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV-1 Transcription in a Phase IIb Trial.

Clin Pharmacol Ther 2019 Mar 9;105(3):692-702. Epub 2018 Oct 9.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpt.1220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379104PMC
March 2019

Vaccine protection against SIVmac239 acquisition.

Proc Natl Acad Sci U S A 2019 01 14;116(5):1739-1744. Epub 2019 Jan 14.

Department of Pathology, Miller School of Medicine, University of Miami, Miami, FL 33136;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1814584116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358712PMC
January 2019

Ultrasensitive Immunoassay for Simian Immunodeficiency Virus p27.

AIDS Res Hum Retroviruses 2018 11 10;34(11):993-1001. Epub 2018 Jul 10.

1 AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute , Leidos Biomedical Research, Inc., Frederick, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/AID.2018.0075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238615PMC
November 2018

Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen.

Cell Rep 2018 Aug;24(8):1958-1966.e5

Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Biological Sciences and the Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2018.07.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113929PMC
August 2018

Early Sites of Virus Replication After Oral SIV Infection of Infant Macaques: Implications for Pathogenesis.

AIDS Res Hum Retroviruses 2018 03 17;34(3):286-299. Epub 2018 Jan 17.

2 Department of Microbiology and Immunology and Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/AID.2017.0169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863100PMC
March 2018

Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection.

Sci Transl Med 2017 Aug;9(402)

Department of Microbiology and Immunology at the Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria 3000, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scitranslmed.aaf1483DOI Listing
August 2017

CXCR5-Dependent Entry of CD8 T Cells into Rhesus Macaque B-Cell Follicles Achieved through T-Cell Engineering.

J Virol 2017 06 12;91(11). Epub 2017 May 12.

AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.02507-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432868PMC
June 2017

Nonhuman primate models for the evaluation of HIV-1 preventive vaccine strategies: model parameter considerations and consequences.

Curr Opin HIV AIDS 2016 11;11(6):546-554

AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/COH.0000000000000311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100008PMC
November 2016

HIV-1 Vpu Mediates HLA-C Downregulation.

Cell Host Microbe 2016 May;19(5):686-95

Cancer and Inflammation Program, Leidos Biomedical Research, Frederick National Laboratory, Frederick, MD 21702, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139-3583, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chom.2016.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904791PMC
May 2016

Mucosal Humoral Immune Response to SIVmac239∆nef Vaccination and Vaginal Challenge.

J Immunol 2016 Mar 10;196(6):2809-18. Epub 2016 Feb 10.

Department of Microbiology and Immunology, Medical School, University of Minnesota, Minneapolis, MN 55455;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1500156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779663PMC
March 2016

Defining HIV and SIV Reservoirs in Lymphoid Tissues.

Pathog Immun 2016 ;1(1):68-106

AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943335PMC
January 2016

Effects of treatment with suppressive combination antiretroviral drug therapy and the histone deacetylase inhibitor suberoylanilide hydroxamic acid; (SAHA) on SIV-infected Chinese rhesus macaques.

PLoS One 2014 17;9(7):e102795. Epub 2014 Jul 17.

Tulane National Primate Research Center, Covington, Louisiana, United States of America; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102795PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102539PMC
November 2015

Michael Piatak, Jr: virtuoso of viral quantification.

Authors:
Jeffrey D Lifson

J Med Primatol 2015 Oct;44(5):224-6

AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD, 21702, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jmp.12180DOI Listing
October 2015

Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides.

Retrovirology 2015 Jun 16;12:49. Epub 2015 Jun 16.

Retroviral Evolution Section, AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Building 535, Rm. 408, Frederick, MD, 21702-1201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12977-015-0175-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469405PMC
June 2015

Relative expression levels of the HLA class-I proteins in normal and HIV-infected cells.

J Immunol 2015 Apr 9;194(8):3594-600. Epub 2015 Mar 9.

Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, MD 21702; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139

View Article

Download full-text PDF

Source
http://www.jimmunol.org/content/early/2015/03/07/jimmunol.14
Web Search
http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1403234
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1403234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390493PMC
April 2015

CD8 T cell response maturation defined by anentropic specificity and repertoire depth correlates with SIVΔnef-induced protection.

PLoS Pathog 2015 Feb 17;11(2):e1004633. Epub 2015 Feb 17.

New England Primate Research Center, Harvard Medical School, Southborough Campus, Southborough, Massachusetts, United States of America; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1004633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334552PMC
February 2015

HIV: Seeking ultimate victory.

Nature 2015 Jan 7;517(7534):281-2. Epub 2015 Jan 7.

AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, Maryland 21702, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14194DOI Listing
January 2015

Maturation of the HIV-1 core by a non-diffusional phase transition.

Nat Commun 2015 Jan 8;6:5854. Epub 2015 Jan 8.

Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

View Article

Download full-text PDF

Source
http://search.proquest.com/openview/97a5f785ecef05150fd6326d
Web Search
http://www.nature.com/doifinder/10.1038/ncomms6854
Publisher Site
http://dx.doi.org/10.1038/ncomms6854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288007PMC
January 2015

Obituary: Remembering Michael Piatak, Jr.

Authors:
Jeffrey D Lifson

Retrovirology 2014 Dec 16;11:92. Epub 2014 Dec 16.

AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc,, Frederick National Laboratory, Frederick 27102, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12977-014-0092-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266953PMC
December 2014

Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3.

J Immunol 2014 Nov 24;193(9):4590-601. Epub 2014 Sep 24.

Division of Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1401781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201991PMC
November 2014