Jeffrey D Browning

Jeffrey D Browning

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Jeffrey D Browning

Jeffrey D Browning

Publications by authors named "Jeffrey D Browning"

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Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver.

Metab Eng 2020 05 28;59:1-14. Epub 2019 Dec 28.

Center for Human Nutrition, The University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2019.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108978PMC
May 2020

Dallas Steatosis Index Identifies Patients With Nonalcoholic Fatty Liver Disease.

Clin Gastroenterol Hepatol 2020 Jan 23. Epub 2020 Jan 23.

Division of Gastroenterology, Department of Medicine, Washington University School of Medicine in Saint Louis, St. Louis, Missouri.

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http://dx.doi.org/10.1016/j.cgh.2020.01.020DOI Listing
January 2020

Crohn's Disease Is Associated With an Increased Prevalence of Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study Using Magnetic Resonance Proton Density Fat Fraction Mapping.

Clin Gastroenterol Hepatol 2019 12 12;17(13):2816-2818. Epub 2019 Mar 12.

Division of Gastroenterology and Inflammatory Bowel Diseases Center, Washington University in St. Louis, St. Louis, Missouri. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.02.045DOI Listing
December 2019

Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver.

Cell Metab 2019 06 18;29(6):1291-1305.e8. Epub 2019 Apr 18.

Center for Human Nutrition, The University of Texas Southwestern Medical Center, Dallas, TX, USA; Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131193018
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http://dx.doi.org/10.1016/j.cmet.2019.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585968PMC
June 2019

Fatty liver disrupts glycerol metabolism in gluconeogenic and lipogenic pathways in humans.

J Lipid Res 2018 09 27;59(9):1685-1694. Epub 2018 Jul 27.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390.

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http://dx.doi.org/10.1194/jlr.M086405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121920PMC
September 2018

Cytosolic phosphoenolpyruvate carboxykinase as a cataplerotic pathway in the small intestine.

Am J Physiol Gastrointest Liver Physiol 2018 08 6;315(2):G249-G258. Epub 2018 Apr 6.

Advanced Imaging Research Center, The University of Texas Southwestern Medical Center , Dallas, Texas.

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http://dx.doi.org/10.1152/ajpgi.00039.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139646PMC
August 2018

Advances in Pediatric Urinary Diversion.

Urol Clin North Am 2018 Feb;45(1):123-132

Department of Urology, University of California, Irvine and Children's Hospital of Orange County, 505 S. Main Street, Orange, CA 92868, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ucl.2017.09.013DOI Listing
February 2018

Limitations of detection of anaplerosis and pyruvate cycling from metabolism of [1-(13)C] acetate.

Nat Med 2015 Feb;21(2):108-9

1] Advanced Imaging Research Center Division of Metabolic Mechanisms of Disease, The University of Texas Southwestern Medical Center, Dallas, Texas, USA. [2] VA North Texas Health Care System, Dallas, Texas, USA.

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http://dx.doi.org/10.1038/nm.3789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425690PMC
February 2015

Influence of liver triglycerides on suppression of glucose production by insulin in men.

J Clin Endocrinol Metab 2015 Jan;100(1):235-43

Advanced Imaging Research Center (E.S.J., J.D.Br., J.D.Ba., C.R.M.), University of Texas Southwestern Medical Center, Dallas, Texas 75390-8568; Department of Internal Medicine (E.S.J., M.S.-G., J.D.B., C.R.M.), University of Texas Southwestern Medical Center, Dallas, Texas 75390; Department of Medicine (N.A.), Division of Endocrinology, University of Texas Medical Branch at Galveston, Texas 77555; Department of Radiology (C.R.M.), University of Texas Southwestern Medical Center, Dallas, Texas 75390; and VA North Texas Health Care System (C.R.M.), Dallas, Texas 75216.

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http://dx.doi.org/10.1210/jc.2014-2404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283006PMC
January 2015

A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice.

J Lipid Res 2014 Dec 30;55(12):2541-53. Epub 2014 Sep 30.

Advanced Imaging Research Center-Division of Metabolic Mechanisms of Disease, The University of Texas Southwestern Medical Center, Dallas, TX Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1194/jlr.M052308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242447PMC
December 2014

Fat and iron quantification in the liver: past, present, and future.

Top Magn Reson Imaging 2014 Apr;23(2):73-94

From the *Department of Radiology, †Advanced Imaging Research Center, and ‡Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1097/RMR.0000000000000016DOI Listing
April 2014

Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease.

Gastroenterology 2014 Mar 4;146(3):726-35. Epub 2013 Dec 4.

Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085130173
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http://dx.doi.org/10.1053/j.gastro.2013.11.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276362PMC
March 2014

Common genetic variants and nonalcoholic Fatty liver disease.

Clin Gastroenterol Hepatol 2013 Sep 21;11(9):1191-3. Epub 2013 May 21.

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http://dx.doi.org/10.1016/j.cgh.2013.05.013DOI Listing
September 2013

Metabolomics, stable isotopes, and A-β+ ketosis-prone diabetes.

Diabetes 2013 Mar;62(3):682-4

Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.2337/db12-1347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581205PMC
March 2013

Use of (2)H(2)O for estimating rates of gluconeogenesis: determination and correction of error due to transaldolase exchange.

Am J Physiol Endocrinol Metab 2012 Dec 2;303(11):E1304-12. Epub 2012 Oct 2.

The Advanced Imaging Research Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA.

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http://www.physiology.org/doi/10.1152/ajpendo.00306.2012
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http://dx.doi.org/10.1152/ajpendo.00306.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774082PMC
December 2012

Adiponectin as an independent predictor of the presence and degree of hepatic steatosis in the Dallas Heart Study.

J Clin Endocrinol Metab 2012 Jun 21;97(6):E982-6. Epub 2012 Mar 21.

University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-8521, USA.

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http://dx.doi.org/10.1210/jc.2011-3305DOI Listing
June 2012

T2 measurement of J-coupled metabolites in the human brain at 3T.

NMR Biomed 2012 Apr 15;25(4):523-9. Epub 2011 Aug 15.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1002/nbm.1767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852663PMC
April 2012

The effect of short-term fasting on liver and skeletal muscle lipid, glucose, and energy metabolism in healthy women and men.

J Lipid Res 2012 Mar 3;53(3):577-86. Epub 2011 Dec 3.

Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.

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http://dx.doi.org/10.1194/jlr.P020867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276482PMC
March 2012

Hepatic triglyceride content in individuals with reduced intestinal cholesterol absorption due to variants in Nieman Pick C1-like 1.

Hepatology 2011 Aug;54(2):736-7

Department of Internal Medicine, Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://doi.wiley.com/10.1002/hep.24461
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http://dx.doi.org/10.1002/hep.24461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492950PMC
August 2011

Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction.

Am J Clin Nutr 2011 May 2;93(5):1048-52. Epub 2011 Mar 2.

Departments of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.

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http://dx.doi.org/10.3945/ajcn.110.007674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076656PMC
May 2011

Fasting reduces plasma proprotein convertase, subtilisin/kexin type 9 and cholesterol biosynthesis in humans.

J Lipid Res 2010 Nov 16;51(11):3359-63. Epub 2010 Aug 16.

Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.

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http://dx.doi.org/10.1194/jlr.P009860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952577PMC
November 2010

Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet.

Am J Physiol Endocrinol Metab 2010 Jun 16;298(6):E1226-35. Epub 2010 Mar 16.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390-8568, USA.

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http://www.physiology.org/doi/10.1152/ajpendo.00033.2010
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http://dx.doi.org/10.1152/ajpendo.00033.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886525PMC
June 2010

Colonoscopy: an unusual complication.

Gastroenterology 2010 Feb 22;138(2):434, 794. Epub 2009 Dec 22.

Department of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1053/j.gastro.2009.08.072DOI Listing
February 2010

New imaging techniques for non-alcoholic steatohepatitis.

Clin Liver Dis 2009 Nov;13(4):607-19

Department of Internal Medicine and Advanced Imaging Research Center, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8568, USA.

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http://dx.doi.org/10.1016/j.cld.2009.07.002DOI Listing
November 2009

Ethnic differences in hepatic steatosis: an insulin resistance paradox?

Hepatology 2009 Mar;49(3):791-801

Department of Internal Medicine, Dallas, TX, USA.

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http://dx.doi.org/10.1002/hep.22726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675577PMC
March 2009

Alterations in hepatic glucose and energy metabolism as a result of calorie and carbohydrate restriction.

Hepatology 2008 Nov;48(5):1487-96

Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, TX, USA.

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http://dx.doi.org/10.1002/hep.22504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701295PMC
November 2008

A case of diarrhea, ataxia, and capsule endoscope retention.

Dig Dis Sci 2007 Nov 4;52(11):3174-7. Epub 2007 Apr 4.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1007/s10620-007-9771-yDOI Listing
November 2007

Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of hepatic gluconeogenesis in the intact mouse liver.

Cell Metab 2007 Apr;5(4):313-20

The Advanced Imaging Research Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75235-9085, USA.

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http://dx.doi.org/10.1016/j.cmet.2007.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680089PMC
April 2007

Statins and hepatic steatosis: perspectives from the Dallas Heart Study.

Hepatology 2006 Aug;44(2):466-71

Donald W. Reynolds Cardiovascular Clinical Research Center, Department of Internal Medicine and Advanced Imaging Research Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9085, USA.

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http://dx.doi.org/10.1002/hep.21248DOI Listing
August 2006

A low-carbohydrate diet rapidly and dramatically reduces intrahepatic triglyceride content.

Hepatology 2006 Aug;44(2):487-8

Advanced Imaging Research Center, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9085, USA.

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http://dx.doi.org/10.1002/hep.21264DOI Listing
August 2006

Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population.

Am J Physiol Endocrinol Metab 2005 Feb 31;288(2):E462-8. Epub 2004 Aug 31.

DW Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-8899, USA.

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http://dx.doi.org/10.1152/ajpendo.00064.2004DOI Listing
February 2005

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity.

Hepatology 2004 Dec;40(6):1387-95

Donald W. Reynolds Cardiovascular Clinical Research Center, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9046, USA.

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http://dx.doi.org/10.1002/hep.20466DOI Listing
December 2004

Molecular mediators of hepatic steatosis and liver injury.

J Clin Invest 2004 Jul;114(2):147-52

Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, 75390-9046, USA.

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http://dx.doi.org/10.1172/JCI22422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC449757PMC
July 2004

Ethnic differences in the prevalence of cryptogenic cirrhosis.

Am J Gastroenterol 2004 Feb;99(2):292-8

Department of Internal Medicine, Division of Digestive and Liver Diseases, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9151, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2004.04059.xDOI Listing
February 2004

Gallstone disease and its complications.

Semin Gastrointest Dis 2003 Oct;14(4):165-77

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046, USA.

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October 2003