Jeffrey Baron

Jeffrey Baron

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Jeffrey Baron

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Persistent Sox9 expression in hypertrophic chondrocytes suppresses transdifferentiation into osteoblasts.

Bone 2019 Aug 20;125:169-177. Epub 2019 May 20.

Section on Growth and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, United States of America.

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http://dx.doi.org/10.1016/j.bone.2019.05.027DOI Listing
August 2019

Advancing treatment of acute myeloid leukemia: the future of FLT3 inhibitors.

Expert Rev Anticancer Ther 2019 Mar 6;19(3):273-286. Epub 2019 Feb 6.

a Leukemia Service, Department of Medicine , Roswell Park Comprehensive Cancer Center , Buffalo , NY , USA.

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https://www.tandfonline.com/doi/full/10.1080/14737140.2019.1
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http://dx.doi.org/10.1080/14737140.2019.1573679DOI Listing
March 2019

Cartilage-Targeted IGF-1 Treatment to Promote Longitudinal Bone Growth.

Mol Ther 2019 03 1;27(3):673-680. Epub 2019 Feb 1.

Section on Growth and Development, National Institute of Child Health and Development, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ymthe.2019.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404097PMC
March 2019

QRICH1 mutations cause a chondrodysplasia with developmental delay.

Clin Genet 2019 Jan 26;95(1):160-164. Epub 2018 Oct 26.

Section on Growth and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.

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http://doi.wiley.com/10.1111/cge.13457
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http://dx.doi.org/10.1111/cge.13457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353565PMC
January 2019

Combining blinatumomab with targeted therapy for BCR-ABL mutant relapsed/refractory acute lymphoblastic leukemia.

Leuk Lymphoma 2018 08 18;59(8):2011-2013. Epub 2017 Dec 18.

b Leukemia Service , Roswell Park Cancer Institute , Buffalo , NY , USA.

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http://dx.doi.org/10.1080/10428194.2017.1411595DOI Listing
August 2018

New developments in the genetic diagnosis of short stature.

Curr Opin Pediatr 2018 08;30(4):541-547

Department of Women's and Children's Health, Karolinska Institutet, Stockholm.

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http://dx.doi.org/10.1097/MOP.0000000000000653DOI Listing
August 2018

Monotherapy with High-Dose Once-Daily Tigecycline is Highly Effective Against Acinetobacter baumanii and other Multidrug-Resistant (MDR) Gram-Negative Bacilli (GNB).

Int J Antimicrob Agents 2018 07 1;52(1):119-120. Epub 2018 Mar 1.

Infectious Disease Division, Rhode Island Hospital and The Miriam Hospital, Brown University Alpert School of Medicine Providence, RI.

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https://linkinghub.elsevier.com/retrieve/pii/S09248579183004
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http://dx.doi.org/10.1016/j.ijantimicag.2018.02.011DOI Listing
July 2018

Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions.

PLoS Biol 2018 07 23;16(7):e2005263. Epub 2018 Jul 23.

Section on Growth and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.2005263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056026PMC
July 2018

Gemtuzumab ozogamicin for the treatment of acute myeloid leukemia.

Expert Rev Clin Pharmacol 2018 Jun 11;11(6):549-559. Epub 2018 Jun 11.

b Leukemia Service, Department of Medicine , Roswell Park Comprehensive Cancer Center , Buffalo , NY , USA.

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http://dx.doi.org/10.1080/17512433.2018.1478725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661897PMC
June 2018

Ezh2 Mutations Found in the Weaver Overgrowth Syndrome Cause a Partial Loss of H3K27 Histone Methyltransferase Activity.

J Clin Endocrinol Metab 2018 04;103(4):1470-1478

Section on Growth and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1210/jc.2017-01948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276576PMC
April 2018

mir-374-5p, mir-379-5p, and mir-503-5p Regulate Proliferation and Hypertrophic Differentiation of Growth Plate Chondrocytes in Male Rats.

Endocrinology 2018 03;159(3):1469-1478

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1210/en.2017-00780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839730PMC
March 2018

Once Daily High Dose Tigecycline Is Optimal: Tigecycline PK/PD Parameters Predict Clinical Effectiveness.

J Clin Med 2018 Mar 9;7(3). Epub 2018 Mar 9.

Infectious Disease Division, Winthrop-University Hospital, Mineola, NY 11501, USA.

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http://dx.doi.org/10.3390/jcm7030049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867575PMC
March 2018

Spatial regulation of bone morphogenetic proteins (BMPs) in postnatal articular and growth plate cartilage.

PLoS One 2017 3;12(5):e0176752. Epub 2017 May 3.

Section on Growth and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176752PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414995PMC
September 2017

Midkine and pleiotrophin concentrations in needle biopsies of breast and lung masses.

Cancer Biomark 2017 Sep;20(3):299-307

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.3233/CBM-170145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296221PMC
September 2017

Aggrecan Mutations in Nonfamilial Short Stature and Short Stature Without Accelerated Skeletal Maturation.

J Endocr Soc 2017 Aug 28;1(8):1006-1011. Epub 2017 Jun 28.

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, Maryland 20892.

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http://dx.doi.org/10.1210/js.2017-00229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686699PMC
August 2017

Genetics of Short Stature.

Endocrinol Metab Clin North Am 2017 06 23;46(2):259-281. Epub 2017 Feb 23.

Division of Pediatric Endocrinology, Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Solnavägen 1, Solna 171 77, Sweden; University Hospital, Örebro University, Södra Grev Rosengatan, Örebro 701 85, Sweden.

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http://dx.doi.org/10.1016/j.ecl.2017.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424617PMC
June 2017

Dexrazoxane for cardioprotection in older adults with acute myeloid leukemia.

Leuk Res Rep 2017 14;7:36-39. Epub 2017 Apr 14.

Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, USA.

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http://dx.doi.org/10.1016/j.lrr.2017.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402627PMC
April 2017

Once daily high dose tigecycline - pharmacokinetic/pharmacodynamic based dosing for optimal clinical effectiveness: dosing matters, revisited.

Expert Rev Anti Infect Ther 2017 03 22;15(3):257-267. Epub 2016 Dec 22.

e Infectious Disease Division , Rhode Island Hospital and The Miriam Hospital.

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http://dx.doi.org/10.1080/14787210.2017.1268529DOI Listing
March 2017

EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy.

Nat Commun 2016 11 29;7:13685. Epub 2016 Nov 29.

Section on Growth and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, CRC, Room 1-3330, 10 Center Drive, MSC-1103, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ncomms13685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477487PMC
November 2016

Midkine and Pleiotrophin Concentrations in Amniotic Fluid in Healthy and Complicated Pregnancies.

PLoS One 2016 18;11(4):e0153325. Epub 2016 Apr 18.

Section on Growth and Development, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153325PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835047PMC
August 2016

Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer.

PLoS One 2016 25;11(2):e0149383. Epub 2016 Feb 25.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149383PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767803PMC
July 2016

The Biology of Stature.

J Pediatr 2016 06 26;173:32-8. Epub 2016 Mar 26.

Section on Growth and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2016.02.068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884478PMC
June 2016

Hypertonic Saline for the Treatment of Bronchiolitis in Infants and Young Children: A Critical Review of the Literature.

J Pediatr Pharmacol Ther 2016 Jan-Feb;21(1):7-26

Pharmacy Department, Roswell Park Cancer Institute, Buffalo, New York ; Department of Pharmacy, Winthrop-University Hospital, Mineola, New York ; Department of Clinical Pharmacy Practice, St John's University College of Pharmacy and Health Sciences, Jamaica, New York.

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http://www.jppt.org/doi/10.5863/1551-6776-21.1.7
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http://dx.doi.org/10.5863/1551-6776-21.1.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778699PMC
March 2016

Midkine concentrations in fine-needle aspiration of benign and malignant thyroid nodules.

Clin Endocrinol (Oxf) 2015 Dec 15;83(6):977-84. Epub 2015 Jan 15.

Section on Growth and Development, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/cen.12676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532878PMC
December 2015

Short and tall stature: a new paradigm emerges.

Nat Rev Endocrinol 2015 Dec 6;11(12):735-46. Epub 2015 Oct 6.

Division of Pediatric Endocrinology, Department of Women's and Children's Health, Karolinska Institutet, SE-171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1038/nrendo.2015.165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002943PMC
December 2015

Gene expression profiling reveals similarities between the spatial architectures of postnatal articular and growth plate cartilage.

PLoS One 2014 28;9(7):e103061. Epub 2014 Jul 28.

Pediatric Endocrinology Unit, Department of Women's and Children's Health, Karolinska Institutet and University Hospital, Stockholm, Sweden; Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103061PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113381PMC
November 2015

Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis.

J Bone Miner Res 2015 Oct 10;30(10):1887-95. Epub 2015 May 10.

Unit of Reproductive Endocrinology, Program in Reproductive and Adult Endocrinology (PRAE), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, USA.

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http://dx.doi.org/10.1002/jbmr.2534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590282PMC
October 2015

Regulation of body growth.

Curr Opin Pediatr 2015 Aug;27(4):502-10

Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/MOP.0000000000000235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309954PMC
August 2015

Human monoclonal antibody fragments targeting matrilin-3 in growth plate cartilage.

Pharm Res 2015 Jul 19;32(7):2439-49. Epub 2015 Feb 19.

Section on Growth and Development, National Institute of Child Health and Development, National Institutes of Health, Bldg. 10 CRC, Rm. 1-3330, 10 Center Drive, Bethesda, Maryland, 20892, USA.

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http://dx.doi.org/10.1007/s11095-015-1636-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296366PMC
July 2015

Evidence That Up-Regulation of MicroRNA-29 Contributes to Postnatal Body Growth Deceleration.

Mol Endocrinol 2015 Jun 13;29(6):921-32. Epub 2015 Apr 13.

Section on Growth and Development (F.K., A.A.N., G.R., J.B., J.C.L.) and Section on Neuroendocrinology (S.J.C.), Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892; and Center for Molecular Medicine and Pediatric Endocrinology Unit (A.C.A., O.N.), Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1210/me.2015-1047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447640PMC
June 2015

Spatial regulation of gene expression during growth of articular cartilage in juvenile mice.

Pediatr Res 2015 Mar 18;77(3):406-15. Epub 2014 Dec 18.

Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland.

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http://dx.doi.org/10.1038/pr.2014.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354579PMC
March 2015

Broad shifts in gene expression during early postnatal life are associated with shifts in histone methylation patterns.

PLoS One 2014 28;9(1):e86957. Epub 2014 Jan 28.

Section on Growth and Development, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086957PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904965PMC
December 2014

Defining the role of common variation in the genomic and biological architecture of adult human height.

Authors:
Andrew R Wood Tonu Esko Jian Yang Sailaja Vedantam Tune H Pers Stefan Gustafsson Audrey Y Chu Karol Estrada Jian'an Luan Zoltán Kutalik Najaf Amin Martin L Buchkovich Damien C Croteau-Chonka Felix R Day Yanan Duan Tove Fall Rudolf Fehrmann Teresa Ferreira Anne U Jackson Juha Karjalainen Ken Sin Lo Adam E Locke Reedik Mägi Evelin Mihailov Eleonora Porcu Joshua C Randall André Scherag Anna A E Vinkhuyzen Harm-Jan Westra Thomas W Winkler Tsegaselassie Workalemahu Jing Hua Zhao Devin Absher Eva Albrecht Denise Anderson Jeffrey Baron Marian Beekman Ayse Demirkan Georg B Ehret Bjarke Feenstra Mary F Feitosa Krista Fischer Ross M Fraser Anuj Goel Jian Gong Anne E Justice Stavroula Kanoni Marcus E Kleber Kati Kristiansson Unhee Lim Vaneet Lotay Julian C Lui Massimo Mangino Irene Mateo Leach Carolina Medina-Gomez Michael A Nalls Dale R Nyholt Cameron D Palmer Dorota Pasko Sonali Pechlivanis Inga Prokopenko Janina S Ried Stephan Ripke Dmitry Shungin Alena Stancáková Rona J Strawbridge Yun Ju Sung Toshiko Tanaka Alexander Teumer Stella Trompet Sander W van der Laan Jessica van Setten Jana V Van Vliet-Ostaptchouk Zhaoming Wang Loïc Yengo Weihua Zhang Uzma Afzal Johan Arnlöv Gillian M Arscott Stefania Bandinelli Amy Barrett Claire Bellis Amanda J Bennett Christian Berne Matthias Blüher Jennifer L Bolton Yvonne Böttcher Heather A Boyd Marcel Bruinenberg Brendan M Buckley Steven Buyske Ida H Caspersen Peter S Chines Robert Clarke Simone Claudi-Boehm Matthew Cooper E Warwick Daw Pim A De Jong Joris Deelen Graciela Delgado Josh C Denny Rosalie Dhonukshe-Rutten Maria Dimitriou Alex S F Doney Marcus Dörr Niina Eklund Elodie Eury Lasse Folkersen Melissa E Garcia Frank Geller Vilmantas Giedraitis Alan S Go Harald Grallert Tanja B Grammer Jürgen Gräßler Henrik Grönberg Lisette C P G M de Groot Christopher J Groves Jeffrey Haessler Per Hall Toomas Haller Goran Hallmans Anke Hannemann Catharina A Hartman Maija Hassinen Caroline Hayward Nancy L Heard-Costa Quinta Helmer Gibran Hemani Anjali K Henders Hans L Hillege Mark A Hlatky Wolfgang Hoffmann Per Hoffmann Oddgeir Holmen Jeanine J Houwing-Duistermaat Thomas Illig Aaron Isaacs Alan L James Janina Jeff Berit Johansen Åsa Johansson Jennifer Jolley Thorhildur Juliusdottir Juhani Junttila Abel N Kho Leena Kinnunen Norman Klopp Thomas Kocher Wolfgang Kratzer Peter Lichtner Lars Lind Jaana Lindström Stéphane Lobbens Mattias Lorentzon Yingchang Lu Valeriya Lyssenko Patrik K E Magnusson Anubha Mahajan Marc Maillard Wendy L McArdle Colin A McKenzie Stela McLachlan Paul J McLaren Cristina Menni Sigrun Merger Lili Milani Alireza Moayyeri Keri L Monda Mario A Morken Gabriele Müller Martina Müller-Nurasyid Arthur W Musk Narisu Narisu Matthias Nauck Ilja M Nolte Markus M Nöthen Laticia Oozageer Stefan Pilz Nigel W Rayner Frida Renstrom Neil R Robertson Lynda M Rose Ronan Roussel Serena Sanna Hubert Scharnagl Salome Scholtens Fredrick R Schumacher Heribert Schunkert Robert A Scott Joban Sehmi Thomas Seufferlein Jianxin Shi Karri Silventoinen Johannes H Smit Albert Vernon Smith Joanna Smolonska Alice V Stanton Kathleen Stirrups David J Stott Heather M Stringham Johan Sundström Morris A Swertz Ann-Christine Syvänen Bamidele O Tayo Gudmar Thorleifsson Jonathan P Tyrer Suzanne van Dijk Natasja M van Schoor Nathalie van der Velde Diana van Heemst Floor V A van Oort Sita H Vermeulen Niek Verweij Judith M Vonk Lindsay L Waite Melanie Waldenberger Roman Wennauer Lynne R Wilkens Christina Willenborg Tom Wilsgaard Mary K Wojczynski Andrew Wong Alan F Wright Qunyuan Zhang Dominique Arveiler Stephan J L Bakker John Beilby Richard N Bergman Sven Bergmann Reiner Biffar John Blangero Dorret I Boomsma Stefan R Bornstein Pascal Bovet Paolo Brambilla Morris J Brown Harry Campbell Mark J Caulfield Aravinda Chakravarti Rory Collins Francis S Collins Dana C Crawford L Adrienne Cupples John Danesh Ulf de Faire Hester M den Ruijter Raimund Erbel Jeanette Erdmann Johan G Eriksson Martin Farrall Ele Ferrannini Jean Ferrières Ian Ford Nita G Forouhi Terrence Forrester Ron T Gansevoort Pablo V Gejman Christian Gieger Alain Golay Omri Gottesman Vilmundur Gudnason Ulf Gyllensten David W Haas Alistair S Hall Tamara B Harris Andrew T Hattersley Andrew C Heath Christian Hengstenberg Andrew A Hicks Lucia A Hindorff Aroon D Hingorani Albert Hofman G Kees Hovingh Steve E Humphries Steven C Hunt Elina Hypponen Kevin B Jacobs Marjo-Riitta Jarvelin Pekka Jousilahti Antti M Jula Jaakko Kaprio John J P Kastelein Manfred Kayser Frank Kee Sirkka M Keinanen-Kiukaanniemi Lambertus A Kiemeney Jaspal S Kooner Charles Kooperberg Seppo Koskinen Peter Kovacs Aldi T Kraja Meena Kumari Johanna Kuusisto Timo A Lakka Claudia Langenberg Loic Le Marchand Terho Lehtimäki Sara Lupoli Pamela A F Madden Satu Männistö Paolo Manunta André Marette Tara C Matise Barbara McKnight Thomas Meitinger Frans L Moll Grant W Montgomery Andrew D Morris Andrew P Morris Jeffrey C Murray Mari Nelis Claes Ohlsson Albertine J Oldehinkel Ken K Ong Willem H Ouwehand Gerard Pasterkamp Annette Peters Peter P Pramstaller Jackie F Price Lu Qi Olli T Raitakari Tuomo Rankinen D C Rao Treva K Rice Marylyn Ritchie Igor Rudan Veikko Salomaa Nilesh J Samani Jouko Saramies Mark A Sarzynski Peter E H Schwarz Sylvain Sebert Peter Sever Alan R Shuldiner Juha Sinisalo Valgerdur Steinthorsdottir Ronald P Stolk Jean-Claude Tardif Anke Tönjes Angelo Tremblay Elena Tremoli Jarmo Virtamo Marie-Claude Vohl Philippe Amouyel Folkert W Asselbergs Themistocles L Assimes Murielle Bochud Bernhard O Boehm Eric Boerwinkle Erwin P Bottinger Claude Bouchard Stéphane Cauchi John C Chambers Stephen J Chanock Richard S Cooper Paul I W de Bakker George Dedoussis Luigi Ferrucci Paul W Franks Philippe Froguel Leif C Groop Christopher A Haiman Anders Hamsten M Geoffrey Hayes Jennie Hui David J Hunter Kristian Hveem J Wouter Jukema Robert C Kaplan Mika Kivimaki Diana Kuh Markku Laakso Yongmei Liu Nicholas G Martin Winfried März Mads Melbye Susanne Moebus Patricia B Munroe Inger Njølstad Ben A Oostra Colin N A Palmer Nancy L Pedersen Markus Perola Louis Pérusse Ulrike Peters Joseph E Powell Chris Power Thomas Quertermous Rainer Rauramaa Eva Reinmaa Paul M Ridker Fernando Rivadeneira Jerome I Rotter Timo E Saaristo Danish Saleheen David Schlessinger P Eline Slagboom Harold Snieder Tim D Spector Konstantin Strauch Michael Stumvoll Jaakko Tuomilehto Matti Uusitupa Pim van der Harst Henry Völzke Mark Walker Nicholas J Wareham Hugh Watkins H-Erich Wichmann James F Wilson Pieter Zanen Panos Deloukas Iris M Heid Cecilia M Lindgren Karen L Mohlke Elizabeth K Speliotes Unnur Thorsteinsdottir Inês Barroso Caroline S Fox Kari E North David P Strachan Jacques S Beckmann Sonja I Berndt Michael Boehnke Ingrid B Borecki Mark I McCarthy Andres Metspalu Kari Stefansson André G Uitterlinden Cornelia M van Duijn Lude Franke Cristen J Willer Alkes L Price Guillaume Lettre Ruth J F Loos Michael N Weedon Erik Ingelsson Jeffrey R O'Connell Goncalo R Abecasis Daniel I Chasman Michael E Goddard Peter M Visscher Joel N Hirschhorn Timothy M Frayling

Nat Genet 2014 Nov 5;46(11):1173-86. Epub 2014 Oct 5.

Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.

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http://kooperberg.fhcrc.org/papers/2014wood.pdf
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http://www.nature.com/doifinder/10.1038/ng.3097
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http://dx.doi.org/10.1038/ng.3097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250049PMC
November 2014

Evidence that estrogen hastens epiphyseal fusion and cessation of longitudinal bone growth by irreversibly depleting the number of resting zone progenitor cells in female rabbits.

Endocrinology 2014 Aug 7;155(8):2892-9. Epub 2014 Apr 7.

Program in Developmental Endocrinology and Genetics (O.N., M.W., E.B.M.L., J.L.M., K.M.B., J.B.), Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892; and Center for Molecular Medicine and Pediatric Endocrinology Unit (O.N., E.B.M.L.), Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1210/en.2013-2175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098010PMC
August 2014

Recent research on the growth plate: Recent insights into the regulation of the growth plate.

J Mol Endocrinol 2014 Aug 16;53(1):T1-9. Epub 2014 Apr 16.

Program in Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, CRC, Room 1-3330, 10 Center Drive, MSC 1103, Bethesda, Maryland 20892-1103, USACenter for Molecular Medicine and Pediatric Endocrinology UnitDepartment of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1530/JME-14-0022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133284PMC
August 2014

Short stature, accelerated bone maturation, and early growth cessation due to heterozygous aggrecan mutations.

J Clin Endocrinol Metab 2014 Aug 24;99(8):E1510-8. Epub 2014 Apr 24.

Program in Developmental Endocrinology and Genetics (O.N., J.C.L., J.B.), Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892; Center for Molecular Medicine and Pediatric Endocrinology Unit, Department of Women's and Children's Health (O.N.), Karolinska Institutet and Karolinska University Hospital, SE-171 76 Stockholm, Sweden; Program in Biological and Biomedical Sciences (M.H.G.), Harvard Medical School, Boston, Massachusetts 02115; Connecticut Children's Medical Center (N.D.), Hartford, Connecticut 06106; Children's Hospital of Pittsburgh (J.P., D.F.), University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15224; Division of Endocrinology (M.H.G., C.J., J.N.H., A.D.), Boston Children's Hospital, Boston, Massachusetts 02115; Department of Genetics (M.H.G., J.N.H.), Harvard Medical School, Boston, Massachusetts 02115; and Program in Medical and Population Genetics (J.N.H., A.D.), Broad Institute, Cambridge, Massachusetts 02142.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121031PMC
August 2014

Malnutrition and catch-up growth during childhood and puberty.

World Rev Nutr Diet 2014 16;109:89-100. Epub 2014 Jan 16.

National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803287PMC
July 2014

Evolutionary conservation and modulation of a juvenile growth-regulating genetic program.

J Mol Endocrinol 2014 Jun 28;52(3):269-77. Epub 2014 Apr 28.

Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development Microarray Core Facility, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 10 Center Drive, MSC-1103; Building 10, Room 1-3330, Bethesda, Maryland 20892, USA Department of Pediatrics and the Reproductive Sciences Program, The University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1530/JME-13-0263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051439PMC
June 2014

Identification of chondrocyte-binding peptides by phage display.

J Orthop Res 2013 Jul 25;31(7):1053-8. Epub 2013 Feb 25.

Developmental Endocrinology Branch, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/jor.22325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803314PMC
July 2013

Evidence that Igf2 down-regulation in postnatal tissues and up-regulation in malignancies is driven by transcription factor E2f3.

Proc Natl Acad Sci U S A 2013 Apr 25;110(15):6181-6. Epub 2013 Mar 25.

Section on Growth and Development, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.1219079110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625270PMC
April 2013

Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height.

Hum Mol Genet 2012 Dec 21;21(23):5193-201. Epub 2012 Aug 21.

Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/hmg/dds347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490510PMC
December 2012

A set of imprinted genes required for normal body growth also promotes growth of rhabdomyosarcoma cells.

Pediatr Res 2012 Jan;71(1):32-8

Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/pr.2011.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420822PMC
January 2012

Growth plate senescence and catch-up growth.

Endocr Dev 2011 22;21:23-29. Epub 2011 Aug 22.

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http://dx.doi.org/10.1159/000328117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420820PMC
December 2011

Organization of the Indian hedgehog--parathyroid hormone-related protein system in the postnatal growth plate.

J Mol Endocrinol 2011 Aug;47(1):99-107

Growth and Cartilage Unit, Center for Molecular Medicine and Division of Pediatric Endocrinology, Department of Women’s and Children’s Health, Karolinska Institutet and Karolinska University Hospital, SE-171 76 Stockholm, Sweden.

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August 2011

Mechanisms limiting body growth in mammals.

Endocr Rev 2011 Jun 25;32(3):422-40. Epub 2011 Mar 25.

Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/er.2011-0001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365796PMC
June 2011

Effects of glucocorticoids on the growth plate.

Endocr Dev 2011 16;20:187-193. Epub 2010 Dec 16.

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http://dx.doi.org/10.1159/000321244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445429PMC
March 2011

Growth-inhibiting conditions slow growth plate senescence.

J Endocrinol 2011 Jan 25;208(1):59-67. Epub 2010 Oct 25.

Developmental Endocrinology Branch, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, CRC, Room 1-3330, 10 Center Drive, MSC-1103, Bethesda, Maryland 20892-1103, USA.

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http://dx.doi.org/10.1677/JOE-10-0302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289067PMC
January 2011

Changes in gene expression associated with aging commonly originate during juvenile growth.

Mech Ageing Dev 2010 Oct 9;131(10):641-9. Epub 2010 Sep 9.

Developmental Endocrinology Branch, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1103, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956763PMC
October 2010

Coordinated postnatal down-regulation of multiple growth-promoting genes: evidence for a genetic program limiting organ growth.

FASEB J 2010 Aug 6;24(8):3083-92. Epub 2010 Apr 6.

Developmental Endocrinology Branch, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, CRC, Room 1-3330, 10 Center Dr., MSC-1103, Bethesda, MD 20892-1103, USA.

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August 2010

Spatial and temporal regulation of gene expression in the mammalian growth plate.

Bone 2010 May 22;46(5):1380-90. Epub 2010 Jan 22.

Developmental Endocrinology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418671PMC
May 2010

Hormones and genes of importance in bone physiology and their influence on bone mineralization and growth in Turner syndrome.

Horm Res Paediatr 2010 3;73(3):161-5. Epub 2010 Mar 3.

Department of Women's and Children's Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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May 2010

An extensive genetic program occurring during postnatal growth in multiple tissues.

Endocrinology 2009 Apr 26;150(4):1791-800. Epub 2008 Nov 26.

Developmental Endocrinology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1103, USA.

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http://dx.doi.org/10.1210/en.2008-0868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659288PMC
April 2009

An imprinted gene network that controls mammalian somatic growth is down-regulated during postnatal growth deceleration in multiple organs.

Am J Physiol Regul Integr Comp Physiol 2008 Jul 30;295(1):R189-96. Epub 2008 Apr 30.

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494817PMC
July 2008

Catch-up growth after hypothyroidism is caused by delayed growth plate senescence.

Endocrinology 2008 Apr 3;149(4):1820-8. Epub 2008 Jan 3.

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, National Institute of Child Health and Human Development, Bethesda, MD 20892-1103, USA.

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http://dx.doi.org/10.1210/en.2007-0993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276705PMC
April 2008

Wnt gene expression in the post-natal growth plate: regulation with chondrocyte differentiation.

Bone 2007 May 20;40(5):1361-9. Epub 2007 Jan 20.

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941840PMC
May 2007

Gradients in bone morphogenetic protein-related gene expression across the growth plate.

J Endocrinol 2007 Apr;193(1):75-84

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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April 2007

Fibroblast growth factor expression in the postnatal growth plate.

Bone 2007 Mar 13;40(3):577-86. Epub 2006 Dec 13.

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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March 2007

Childhood bone mass acquisition and peak bone mass may not be important determinants of bone mass in late adulthood.

Pediatrics 2007 Mar;119 Suppl 2:S131-6

Section on Growth and Development, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1103, USA.

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March 2007

Atraumatic odontoid fractures in patients with rheumatoid arthritis.

Spine J 2006 Sep-Oct;6(5):529-33

Center for Advanced Spinal Surgery, Southwest Orthopaedic Surgery Specialists, PLC, 3395 N Campbell Avenue, Tucson, AZ 85719, USA.

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http://dx.doi.org/10.1016/j.spinee.2005.09.012DOI Listing
January 2007

Three-level bilateral pediculolysis following osteoporotic lumbar compression fracture.

Spine J 2006 Sep-Oct;6(5):539-43. Epub 2006 Jul 24.

Department of Orthopaedics, University of Arizona, 5109 Warren Avenue, Tucson, AZ 85756, USA.

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January 2007

The role of p27Kip1 in the regulation of growth plate chondrocyte proliferation in mice.

Pediatr Res 2006 Sep 20;60(3):288-93. Epub 2006 Jul 20.

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1203/01.pdr.0000232790.53527.c6DOI Listing
September 2006

Bone age and onset of puberty in normal boys.

Mol Cell Endocrinol 2006 Jul 11;254-255:202-6. Epub 2006 Jul 11.

Bone and Extracellular Matrix Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1829, USA.

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http://dx.doi.org/10.1016/j.mce.2006.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1586226PMC
July 2006

Depletion of resting zone chondrocytes during growth plate senescence.

J Endocrinol 2006 Apr;189(1):27-36

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, CRC, Room 1-3330, 10 Center Drive, MSC 1103, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1677/joe.1.06489DOI Listing
April 2006

Endocrine regulation of the growth plate.

Horm Res 2005 4;64(4):157-65. Epub 2005 Oct 4.

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1862, USA.

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December 2005

Catch-up growth: testing the hypothesis of delayed growth plate senescence in humans.

J Pediatr 2005 Dec;147(6):843-6

Department of Pediatrics, Leiden University Medical Center, Leiden, the Netherlands.

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December 2005

Lack of telomere shortening with age in mouse resting zone chondrocytes.

Horm Res 2005 24;63(3):125-8. Epub 2005 Mar 24.

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1159/000084687DOI Listing
August 2005

Growth plate senescence is associated with loss of DNA methylation.

J Endocrinol 2005 Jul;186(1):241-9

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1677/joe.1.06016DOI Listing
July 2005

Impact of growth plate senescence on catch-up growth and epiphyseal fusion.

Pediatr Nephrol 2005 Mar 27;20(3):319-22. Epub 2005 Jan 27.

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://link.springer.com/10.1007/s00467-004-1689-4
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March 2005

Short stature with normal growth hormone stimulation testing: lack of evidence for partial growth hormone deficiency or insensitivity.

Horm Res 2004 13;62(2):97-102. Epub 2004 Jul 13.

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

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February 2005

Fundamental limits on longitudinal bone growth: growth plate senescence and epiphyseal fusion.

Trends Endocrinol Metab 2004 Oct;15(8):370-4

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.tem.2004.08.004DOI Listing
October 2004

Growth hormone therapy and bone mineral density in Turner syndrome.

J Clin Endocrinol Metab 2004 Oct;89(10):4886-9

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 , USA.

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http://dx.doi.org/10.1210/jc.2004-0481DOI Listing
October 2004

Effect of growth hormone treatment on adult height in peripubertal children with idiopathic short stature: a randomized, double-blind, placebo-controlled trial.

J Clin Endocrinol Metab 2004 Jul;89(7):3140-8

Developmental Endocrinology Branch, National Institute of Child Health and Human Development/NIH, Building 10, Room 10N262, 10 Center Drive, MSC 1862, Bethesda, MD 20892-1862, USA.

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http://dx.doi.org/10.1210/jc.2003-031457DOI Listing
July 2004

Overdiagnosis of osteoporosis in children due to misinterpretation of dual-energy x-ray absorptiometry (DEXA).

J Pediatr 2004 Feb;144(2):253-7

Unit on Growth and Development, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1862, USA.

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http://dx.doi.org/10.1016/j.jpeds.2003.08.054DOI Listing
February 2004

Determinants of growth during gonadotropin-releasing hormone analog therapy for precocious puberty.

J Clin Endocrinol Metab 2004 Jan;89(1):103-7

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1862, USA.

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http://dx.doi.org/10.1210/jc.2002-021999DOI Listing
January 2004

In boys with abnormal developmental tempo, maturation of the skeleton and the hypothalamic-pituitary-gonadal axis remains synchronous.

J Clin Endocrinol Metab 2004 Jan;89(1):236-41

Developmental Endocrinology Branch, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/jc.2002-021954DOI Listing
January 2004

Selective reduction in cortical bone mineral density in turner syndrome independent of ovarian hormone deficiency.

J Clin Endocrinol Metab 2003 Dec;88(12):5717-22

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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December 2003

Mechanisms responsible for longitudinal growth of the cortex: coalescence of trabecular bone into cortical bone.

J Bone Joint Surg Am 2003 Sep;85(9):1739-48

Unit of Growth and Development, Developmental Endocrinology Branch, National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.2106/00004623-200309000-00013DOI Listing
September 2003

Bone mineral density and fractures in Turner syndrome.

Am J Med 2003 Sep;115(4):259-64

Developmental Endocrinology Branch, National Institute of Child Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1016/s0002-9343(03)00364-4DOI Listing
September 2003

Effects of powdered versus liquid barium on the viscosity of fluids used in modified swallow studies.

Can Assoc Radiol J 2003 Jun;54(3):152-4

Department of Radiology, University of Alberta, 8440-112 St., Edmonton AB T6G 2B7.

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June 2003

Raloxifene acts as an estrogen agonist on the rabbit growth plate.

Endocrinology 2003 Apr;144(4):1481-5

Pediatric Endocrinology Unit, Department of Women and Child Health, Karolinska Institutet, SE-17176 Stockholm, Sweden.

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http://dx.doi.org/10.1210/en.2002-221108DOI Listing
April 2003

Recovery from osteoporosis through skeletal growth: early bone mass acquisition has little effect on adult bone density.

FASEB J 2002 May 26;16(7):736-8. Epub 2002 Mar 26.

Unit on Growth and Development, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1862, USA.

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http://dx.doi.org/10.1096/fj.01-0640fjeDOI Listing
May 2002

The role of the resting zone in growth plate chondrogenesis.

Endocrinology 2002 May;143(5):1851-7

Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Building 10, Room 10N262, 10 Center Drive MSC 1862, Bethesda, MD 20892, USA.

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May 2002