Jeffrey B Carroll

Jeffrey B Carroll

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Jeffrey B Carroll

Jeffrey B Carroll

Publications by authors named "Jeffrey B Carroll"

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25Publications

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HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation.

PLoS One 2015 21;10(8):e0134465. Epub 2015 Aug 21.

Center for Human Genetic Research, Massachusetts General Hospital, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America; The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134465PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546654PMC
May 2016

Treating the whole body in Huntington's disease.

Lancet Neurol 2015 Nov;14(11):1135-42

Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK.

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http://dx.doi.org/10.1016/S1474-4422(15)00177-5DOI Listing
November 2015

A fully humanized transgenic mouse model of Huntington disease.

Hum Mol Genet 2013 Jan 21;22(1):18-34. Epub 2012 Sep 21.

Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada V5Z 4H4.

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http://dx.doi.org/10.1093/hmg/dds397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606012PMC
January 2013

HDBuzz: empowering patients through accessible education.

Trends Mol Med 2012 Jan 21;18(1):1-3. Epub 2011 Oct 21.

Department of Neurodegenerative Disease, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1016/j.molmed.2011.09.003DOI Listing
January 2012

Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin.

Mol Ther 2011 Dec 4;19(12):2178-85. Epub 2011 Oct 4.

Program in Neuroscience, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/mt.2011.201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242664PMC
December 2011

Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.

Hum Mol Genet 2011 Sep 2;20(17):3356-65. Epub 2011 Jun 2.

Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada V5Z 4H4.

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http://dx.doi.org/10.1093/hmg/ddr242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153302PMC
September 2011

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.

Mol Neurodegener 2011 Aug 19;6:59. Epub 2011 Aug 19.

Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, V5Z 4H4, Canada.

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http://dx.doi.org/10.1186/1750-1326-6-59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180273PMC
August 2011

Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease.

Neurobiol Dis 2011 Jul 31;43(1):257-65. Epub 2011 Mar 31.

Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada V5Z 4H4.

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http://linkinghub.elsevier.com/retrieve/pii/S096999611100100
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http://dx.doi.org/10.1016/j.nbd.2011.03.018DOI Listing
July 2011

CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup.

Am J Hum Genet 2009 Mar 26;84(3):351-66. Epub 2009 Feb 26.

Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, BC, Canada.

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http://dx.doi.org/10.1016/j.ajhg.2009.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668007PMC
March 2009

Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease.

J Neurosci 2009 Feb;29(8):2414-27

Mental Retardation Research Center, The David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5687-08.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670193PMC
February 2009

Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus.

Hum Mol Genet 2008 Aug 29;17(15):2390-404. Epub 2008 Apr 29.

Centre for Molecular Medicine and Therapeutics, University of British Columbia, 980 West 28th Avenue,Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1093/hmg/ddn139DOI Listing
August 2008

Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease.

Neuroimage 2008 Jun 26;41(2):243-51. Epub 2008 Feb 26.

The Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2008.02.019DOI Listing
June 2008

Automated deformation analysis in the YAC128 Huntington disease mouse model.

Neuroimage 2008 Jan 31;39(1):32-9. Epub 2007 Aug 31.

Mouse Imaging Centre (MICe), Hospital for Sick Children, 555 University Ave., Toronto, ON, Canada M5G 1X8.

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http://dx.doi.org/10.1016/j.neuroimage.2007.08.033DOI Listing
January 2008

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.

Hum Mol Genet 2007 Sep 5;16(18):2187-98. Epub 2007 Jul 5.

Department of Pharmacological Sciences, University of Milan, Italy.

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http://dx.doi.org/10.1093/hmg/ddm170DOI Listing
September 2007

Parvoviral nuclear import: bypassing the host nuclear-transport machinery.

J Gen Virol 2006 Nov;87(Pt 11):3209-13

Department of Zoology, University of British Columbia, 6270 University Boulevard, Vancouver, BC V6T 1Z4, Canada.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.82232-0DOI Listing
November 2006