Jeffery M Klco

Jeffery M Klco

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Jeffery M Klco

Jeffery M Klco

Publications by authors named "Jeffery M Klco"

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42Publications

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Immune Escape of Relapsed AML Cells after Allogeneic Transplantation.

N Engl J Med 2018 12 31;379(24):2330-2341. Epub 2018 Oct 31.

From the Division of Oncology, Department of Internal Medicine (M.J.C., A.A.P., M.P.R., C.A.M., E.C., N.M.H., L.D.W., J.S.W., S.E.H., D.C.L., M.J.W., P.W., T.J.L., J.F.D.), the McDonnell Genome Institute (A.A.P., C.A.M., M.O., C.C.F., R.S.F., L.D.W., T.J.L.), the Department of Pathology and Immunology (E.J.D., J.E.P.), and the Division of Biostatistics (J.D.B.), Washington University in St. Louis, St. Louis; the Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN (J.M.K.); the Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH (R.K.W.); and the Center for Cancer Research, Massachusetts General Hospital, Boston (T.A.G.).

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http://www.nejm.org/doi/10.1056/NEJMoa1808777
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http://dx.doi.org/10.1056/NEJMoa1808777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322675PMC
December 2018

Comprehensive discovery of noncoding RNAs in acute myeloid leukemia cell transcriptomes.

Exp Hematol 2017 11 28;55:19-33. Epub 2017 Jul 28.

The McDonnell Genome Institute, Washington University, St. Louis, MO; Department of Medicine, Washington University, St. Louis, MO; Siteman Cancer Center, Washington University, St. Louis, MO; Department of Biomedical Engineering, Washington University, St. Louis, MO. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2017.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772960PMC
November 2017

The genomic landscape of pediatric myelodysplastic syndromes.

Nat Commun 2017 11 16;8(1):1557. Epub 2017 Nov 16.

Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Mail Stop 342, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41467-017-01590-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691144PMC
November 2017

Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse.

PLoS One 2015 23;10(3):e0120585. Epub 2015 Mar 23.

Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120585PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370741PMC
December 2015

Optimizing cancer genome sequencing and analysis.

Cell Syst 2015 Sep;1(3):210-223

The McDonnell Genome Institute, Washington University, St. Louis, MO, USA, 63108 ; Department of Genetics, Washington University, St. Louis, MO, USA, 63108 ; Siteman Cancer Center, Washington University, St. Louis, MO, USA, 63108 ; Department of Medicine, Washington University, St. Louis, MO, USA, 63108.

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http://dx.doi.org/10.1016/j.cels.2015.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669575PMC
September 2015

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.

Cancer Cell 2014 Mar 6;25(3):379-92. Epub 2014 Mar 6.

The Genome Institute, Washington University, St. Louis, MO 63110, USA; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983786PMC
March 2014

Notch signaling in acute promyelocytic leukemia.

Leukemia 2013 Jul 4;27(7):1548-1557. Epub 2013 Mar 4.

Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1038/leu.2013.68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872828PMC
July 2013

Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice.

PLoS One 2012 8;7(10):e46529. Epub 2012 Oct 8.

Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046529PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466302PMC
June 2013

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.

N Engl J Med 2013 05 1;368(22):2059-74. Epub 2013 May 1.

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http://dx.doi.org/10.1056/NEJMoa1301689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767041PMC
May 2013

Use of classic and novel immunohistochemical markers in the diagnosis of cutaneous myeloid sarcoma.

J Cutan Pathol 2011 Dec;38(12):945-53

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.

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http://dx.doi.org/10.1111/j.1600-0560.2011.01809.xDOI Listing
December 2011

Combination decitabine, arsenic trioxide, and ascorbic acid for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a phase I study.

Am J Hematol 2011 Sep 3;86(9):796-800. Epub 2011 Aug 3.

Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1002/ajh.22092DOI Listing
September 2011

Immunohistochemical analysis of monocytic leukemias: usefulness of CD14 and Kruppel-like factor 4, a novel monocyte marker.

Am J Clin Pathol 2011 May;135(5):720-30

Dept of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1309/AJCPZ46PMMAWJROTDOI Listing
May 2011

Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells.

Physiol Genomics 2011 Feb 23;43(3):174-86. Epub 2010 Nov 23.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00084.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055710PMC
February 2011

Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice.

Blood 2011 Feb 29;117(8):2460-8. Epub 2010 Dec 29.

Section of Stem Cell Biology, Division of Oncology, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1182/blood-2010-08-300087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317790PMC
February 2011

Molecular pathology of myeloproliferative neoplasms.

Am J Clin Pathol 2010 Apr;133(4):602-15

Dept of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1309/AJCPPPZ1WFVGNE4ADOI Listing
April 2010

Bone marrow biopsy in patients with hepatitis C virus infection: spectrum of findings and diagnostic utility.

Am J Hematol 2010 Feb;85(2):106-10

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA.

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http://doi.wiley.com/10.1002/ajh.21600
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http://dx.doi.org/10.1002/ajh.21600DOI Listing
February 2010

The spectrum of adult B-lymphoid leukemias with BCR-ABL: molecular diagnostic, cytogenetic, and clinical laboratory perspectives.

Am J Hematol 2008 Dec;83(12):901-7

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/ajh.21291DOI Listing
December 2008

Structure of the complement factor 5a receptor-ligand complex studied by disulfide trapping and molecular modeling.

J Biol Chem 2008 Mar 14;283(12):7763-75. Epub 2008 Jan 14.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M709467200DOI Listing
March 2008

Genetic analysis of the first and third extracellular loops of the C5a receptor reveals an essential WXFG motif in the first loop.

J Biol Chem 2006 Apr 27;281(17):12010-9. Epub 2006 Feb 27.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M600548200
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http://dx.doi.org/10.1074/jbc.M600548200DOI Listing
April 2006

Essential role for the second extracellular loop in C5a receptor activation.

Nat Struct Mol Biol 2005 Apr 13;12(4):320-6. Epub 2005 Mar 13.

Department of Medicine, Washington University School of Medicine, Campus Box 8127, 660 S. Euclid Avenue, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/nsmb913DOI Listing
April 2005

Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist.

Proc Natl Acad Sci U S A 2004 Nov 19;101(48):16768-73. Epub 2004 Nov 19.

Division of Chemistry and Chemical Engineering, Beckman Institute, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0407617101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534742PMC
November 2004

pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development.

Mol Cell Biol 2004 Apr;24(8):3251-61

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC381603PMC
http://dx.doi.org/10.1128/mcb.24.8.3251-3261.2004DOI Listing
April 2004

C5a receptor oligomerization. I. Disulfide trapping reveals oligomers and potential contact surfaces in a G protein-coupled receptor.

J Biol Chem 2003 Sep 30;278(37):35345-53. Epub 2003 Jun 30.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M305606200DOI Listing
September 2003