Jeffery L Kutok

Memorial Sloan Kettering Cancer Center, Parker Institute for Cancer Immunotherapy and Swim Across America/Ludwig Collaborative Laboratory, New York, New York 10065, USA.

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November 2016

Intravenous pegylated asparaginase versus intramuscular native Escherichia coli L-asparaginase in newly diagnosed childhood acute lymphoblastic leukaemia (DFCI 05-001): a randomised, open-label phase 3 trial.

Lancet Oncol 2015 Dec 6;16(16):1677-90. Epub 2015 Nov 6.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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December 2015

B-acute lymphoblastic leukemia/lymphoblastic lymphoma.

Authors:

Sanam Loghavi Jeffery L Kutok Jeffrey L Jorgensen

Am J Clin Pathol 2015 Sep;144(3):393-410

From the Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston; and

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September 2015

Phase II evaluation of IPI-926, an oral Hedgehog inhibitor, in patients with myelofibrosis.

Authors:

Koji Sasaki Jason R Gotlib Ruben A Mesa Kate J Newberry Farhad Ravandi Jorge E Cortes Patrick Kelly Jeffery L Kutok Hagop M Kantarjian Srdan Verstovsek

Leuk Lymphoma 2015 Jul 17;56(7):2092-7. Epub 2015 Feb 17.

Department of Leukemia, The University of Texas MD Anderson Cancer Center , Houston, TX , USA.

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July 2015

HSP90 inhibition enhances antimitotic drug-induced mitotic arrest and cell death in preclinical models of non-small cell lung cancer.

Authors:

Brenda C O'Connell Katie O'Callaghan Bonnie Tillotson Mark Douglas Nafeeza Hafeez Kip A West Howard Stern Janid A Ali Paul Changelian Christian C Fritz Vito J Palombella Karen McGovern Jeffery L Kutok

PLoS One 2014 26;9(12):e115228. Epub 2014 Dec 26.

Infinity Pharmaceuticals, Inc., Cambridge, MA, United States of America.

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August 2015

Polymorphisms of the vincristine pathway and response to treatment in children with childhood acute lymphoblastic leukemia.

Authors:

Francesco Ceppi Chloé Langlois-Pelletier Vincent Gagné Julie Rousseau Claire Ciolino Samanta De Lorenzo Kojok M Kevin Diana Cijov Stephen E Sallan Lewis B Silverman Donna Neuberg Jeffery L Kutok Daniel Sinnett Caroline Laverdière Maja Krajinovic

Pharmacogenomics 2014 Jun;15(8):1105-16

Research Center, CHU Sainte-Justine, 3175 Chemin de la Côte-Ste-Catherine, Montréal, H3T 1C5, Québec, Canada.

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June 2014

Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia.

Authors:

Mohsen Ben Tanfous Bahram Sharif-Askari Francesco Ceppi Haithem Laaribi Vincent Gagné Julie Rousseau Malgorzata Labuda Lewis B Silverman Stephen E Sallan Donna Neuberg Jeffery L Kutok Daniel Sinnett Caroline Laverdière Maja Krajinovic

Clin Cancer Res 2015 Jan 6;21(2):329-34. Epub 2014 Jun 6.

Research Center, CHU Sainte-Justine; Departments of Pediatrics; Pharmacology, University of Montreal, Montreal, Qubec, Canada; Departments of

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January 2015

Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity.

Authors:

Marisa O Peluso Veronica T Campbell Joseph A Harari Thomas T Tibbitts Jennifer L Proctor Nigel Whitebread James M Conley Kerry F White Jeffery L Kutok Margaret A Read Karen McGovern Kerrie L Faia

PLoS One 2014 7;9(3):e90534. Epub 2014 Mar 7.

Infinity Pharmaceuticals, Inc., Cambridge, Massachusetts, United States of America.

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December 2014

PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models.

Chem Biol 2013 Nov 7;20(11):1364-74. Epub 2013 Nov 7.

Infinity Pharmaceuticals, Inc., Cambridge, MA 02139, USA.

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November 2013

Impact of promoter polymorphisms in key regulators of the intrinsic apoptosis pathway on the outcome of childhood acute lymphoblastic leukemia.

Authors:

Rocio Sanchez Janick St-Cyr Marie-Eve Lalonde Jasmine Healy Chantal Richer Vincent Gagné Caroline Laverdière Lewis B Silverman Stephen E Sallan Donna Neuberg Jeffery L Kutok Ekaterini A Kritikou Maja Krajinovic Daniel Sinnett

Haematologica 2014 Feb 13;99(2):314-21. Epub 2013 Sep 13.

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February 2014

Bim polymorphisms: influence on function and response to treatment in children with acute lymphoblastic leukemia.

Authors:

Vincent Gagné Julie Rousseau Malgorzata Labuda Bahram Sharif-Askari Ivan Brukner Caroline Laverdière Francesco Ceppi Stephen E Sallan Lewis B Silverman Donna Neuberg Jeffery L Kutok Daniel Sinnett Maja Krajinovic

Clin Cancer Res 2013 Sep 1;19(18):5240-9. Epub 2013 Aug 1.

Authors' Affiliations: Charles Bruneau Cancer Center, Research Center CHU Sainte-Justine; Departments of Pediatrics and Pharmacology, University of Montreal; Department of Diagnostic Medicine, Jewish General Hospital, Montreal, Quebec, Canada; Departments of Pediatric Oncology and Biostatistics and Computational Biology, Dana-Farber Cancer Institute; Division of Hematology/Oncology, Children's Hospital; and Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.

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September 2013

Impact of hemochromatosis gene mutations on cardiac status in doxorubicin-treated survivors of childhood high-risk leukemia.

Authors:

Steven E Lipshultz Stuart R Lipsitz Jeffery L Kutok Tracie L Miller Steven D Colan Donna S Neuberg Kristen E Stevenson Mark D Fleming Stephen E Sallan Vivian I Franco Jacqueline M Henkel Barbara L Asselin Uma H Athale Luis A Clavell Bruno Michon Caroline Laverdiere Eric Larsen Kara M Kelly Lewis B Silverman

Cancer 2013 Oct 16;119(19):3555-62. Epub 2013 Jul 16.

Department of Pediatrics, University of Miami Miller School of Medicine, Miami, Florida; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida.

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October 2013