Publications by authors named "Jee-In Kim"

57Publications

Isocitrate dehydrogenase 2 deficiency aggravates prolonged high-fat diet intake-induced hypertension.

Redox Biol 2020 07 25;34:101548. Epub 2020 Apr 25.

Department of Anatomy, Cardiovascular Research Center and BK21 Plus, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Junggu, Daegu, 41944, Republic of Korea. Electronic address:

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July 2020

Orexin A-induced inhibition of leptin expression and secretion in adipocytes reducing plasma leptin levels and hypothalamic leptin resistance.

Pflugers Arch 2019 12 30;471(11-12):1407-1418. Epub 2019 Oct 30.

Department of Physiology, Keimyung University School of Medicine, 1095 Dalgubeoldae-Ro, Dalseo-Gu, Daegu, 42601, South Korea.

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December 2019

Histone deacetylase inhibitor CG200745 ameliorates high-fat diet-induced hypertension via inhibition of angiotensin II production.

Naunyn Schmiedebergs Arch Pharmacol 2020 03 26;393(3):491-500. Epub 2019 Oct 26.

Department of Molecular Medicine and Medical Research Center, Keimyung University School of Medicine, 1095 Dalgubeol-daero, Dalseo-gu, Daegu, 42601, Republic of Korea.

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March 2020

Repressive effects of red bean, extracts on obesity of mouse induced with high-fat diet via downregulation of adipocyte differentiation and modulating lipid metabolism.

Food Sci Biotechnol 2018 Dec 7;27(6):1811-1821. Epub 2018 Jul 7.

1Department of Biological Science, Andong National University, 1375 Gyungdong-ro, Andong, 36728 South Korea.

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December 2018

Iss2Image: A Novel Signal-Encoding Technique for CNN-Based Human Activity Recognition.

Sensors (Basel) 2018 Nov 13;18(11). Epub 2018 Nov 13.

Department of Computer Science and Engineering, Kyung Hee University, (Global Campus), 1732, Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do 17104, Korea.

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November 2018

Adaptive Data Boosting Technique for Robust Personalized Speech Emotion in Emotionally-Imbalanced Small-Sample Environments.

Sensors (Basel) 2018 Nov 2;18(11). Epub 2018 Nov 2.

Department of Computer Science and Engineering, Kyung Hee University, (Global Campus), 1732, Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do 17104, Korea.

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November 2018

Fragmentation of kidney epithelial cell primary cilia occurs by cisplatin and these cilia fragments are excreted into the urine.

Redox Biol 2019 01 25;20:38-45. Epub 2018 Sep 25.

Department of Anatomy, Cardiovascular Research Institute and BK21 Plus, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Junggu, Daegu 41944, Republic of Korea. Electronic address:

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January 2019

Mitochondrial NADP-dependent isocitrate dehydrogenase deficiency increases cisplatin-induced oxidative damage in the kidney tubule cells.

Cell Death Dis 2018 05 1;9(5):488. Epub 2018 May 1.

Department of Anatomy, Cardiovascular Research Institute and BK21 Plus, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Junggu, Daegu, 41944, Republic of Korea.

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May 2018

Ablation of C/EBP homologous protein attenuates renal fibrosis after ureteral obstruction by reducing autophagy and microtubule disruption.

Biochim Biophys Acta Mol Basis Dis 2018 May 7;1864(5 Pt A):1634-1641. Epub 2018 Feb 7.

Department of Anatomy and BK21 Plus, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Junggu, Daegu 41944, Republic of Korea. Electronic address:

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May 2018

Deficiency of primary cilia in kidney epithelial cells induces epithelial to mesenchymal transition.

Biochem Biophys Res Commun 2018 02 11;496(2):450-454. Epub 2018 Jan 11.

Department of Molecular Medicine and Medical Research Center, Keimyung University School of Medicine, Daegu, Republic of Korea. Electronic address:

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February 2018

Downregulation of exocyst Sec10 accelerates kidney tubule cell recovery through enhanced cell migration.

Biochem Biophys Res Commun 2018 02 8;496(2):309-315. Epub 2018 Jan 8.

Medical Research Center, Keimyung University School of Medicine, Daegu, Republic of Korea; Department of Molecular Medicine Keimyung University School of Medicine, Daegu, Republic of Korea. Electronic address:

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February 2018

The coffee diterpene kahweol enhances sensitivity to sorafenib in human renal carcinoma Caki cells through down-regulation of Mcl-1 and c-FLIP expression.

Oncotarget 2017 Oct 24;8(47):83195-83206. Epub 2017 Aug 24.

Department of Immunology, School of Medicine, Keimyung University, Daegu 704-701, South Korea.

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October 2017

IDH2 deficiency increases the liver susceptibility to ischemia-reperfusion injury via increased mitochondrial oxidative injury.

Redox Biol 2018 04 8;14:142-153. Epub 2017 Sep 8.

Department of Anatomy, Cardiovascular Research Institute and BK21 Plus, Kyungpook National University School of Medicine, 680 Gukchaebosang-ro, Junggu, Daegu 41944, Republic of Korea. Electronic address:

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April 2018

Hydrogen sulfide-producing cystathionine γ-lyase is critical in the progression of kidney fibrosis.

Free Radic Biol Med 2017 11 24;112:423-432. Epub 2017 Aug 24.

Department of Anatomy, Cardiovascular Research Institute and BK21 Plus, Kyungpook National University School of Medicine, 680 Gukchaebosang-ro, Junggu, Daegu 41944, Republic of Korea. Electronic address:

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November 2017

Hepatic ischemia/reperfusion injury disrupts the homeostasis of kidney primary cilia via oxidative stress.

Biochim Biophys Acta Mol Basis Dis 2017 07 8;1863(7):1817-1828. Epub 2017 May 8.

Department of Anatomy, Cardiovascular Research Institute and BK21 Plus, Kyungpook National University School of Medicine, 680 Gukchaebosang-ro, Junggu, Daegu 41944, Republic of Korea. Electronic address:

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July 2017

Methionine Sulfoxide Reductase A Deficiency Exacerbates Cisplatin-Induced Nephrotoxicity via Increased Mitochondrial Damage and Renal Cell Death.

Antioxid Redox Signal 2017 Oct 20;27(11):727-741. Epub 2017 Mar 20.

1 Department of Anatomy and BK21 Plus, Kyungpook National University School of Medicine , Junggu, Daegu, Republic of Korea.

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October 2017

High fat diet confers vascular hyper-contractility against angiotensin II through upregulation of MLCK and CPI-17.

Authors:
Jee In Kim

Korean J Physiol Pharmacol 2017 Jan 21;21(1):99-106. Epub 2016 Dec 21.

Department of Molecular Medicine, Keimyung University School of Medicine, Daegu 42601, Korea.

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January 2017

Mitochondrial NADP-Dependent Isocitrate Dehydrogenase Deficiency Exacerbates Mitochondrial and Cell Damage after Kidney Ischemia-Reperfusion Injury.

J Am Soc Nephrol 2017 Apr 7;28(4):1200-1215. Epub 2016 Nov 7.

Department of Anatomy, Cardiovascular Research Institute and Brain Korea 21 Plus, Kyungpook National University School of Medicine, Daegu, Republic of Korea;

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April 2017

Differential modulation of flagella expression in enterohaemorrhagic Escherichia coli O157: H7 by intestinal short-chain fatty acid mixes.

Microbiology (Reading) 2016 10 16;162(10):1761-1772. Epub 2016 Aug 16.

Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.

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October 2016

Inhibition of microtubule dynamics impedes repair of kidney ischemia/reperfusion injury and increases fibrosis.

Sci Rep 2016 06 8;6:27775. Epub 2016 Jun 8.

Department of Anatomy, Cardiovascular Research Institute, and BK21 Plus, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea.

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June 2016

Unilateral nephrectomy elongates primary cilia in the remaining kidney via reactive oxygen species.

Sci Rep 2016 Feb 29;6:22281. Epub 2016 Feb 29.

Department of Anatomy and BK 21 Project, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea.

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February 2016

Methionine sulfoxide reductase A deficiency exacerbates progression of kidney fibrosis induced by unilateral ureteral obstruction.

Free Radic Biol Med 2015 Dec 22;89:201-8. Epub 2015 Jul 22.

Department of Anatomy and BK21 Plus Program, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea. Electronic address:

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December 2015

Hydrogen sulfide accelerates the recovery of kidney tubules after renal ischemia/reperfusion injury.

Nephrol Dial Transplant 2015 Sep 3;30(9):1497-506. Epub 2015 Jul 3.

Department of Anatomy, Cardiovascular Research Institute and BK21 Plus, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea.

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September 2015

C/EBP homologous protein (CHOP) gene deficiency attenuates renal ischemia/reperfusion injury in mice.

Biochim Biophys Acta 2015 Sep 11;1852(9):1895-901. Epub 2015 Jun 11.

Department of Anatomy and BK21 Plus, Kyungpook National University School of Medicine, Daegu, Republic of Korea. Electronic address:

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September 2015

Angiotensin II removes kidney resistance conferred by ischemic preconditioning.

Biomed Res Int 2014 28;2014:602149. Epub 2014 Aug 28.

Department of Anatomy and BK21 Plus Biomedical Convergence Program, Cardiovascular Research Institute, Kyungpook National University School of Medicine, 101 Dongin-dong Jung-gu, Daegu 700-422, Republic of Korea.

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June 2015

Regulator of G protein signaling 2 (RGS2) deficiency accelerates the progression of kidney fibrosis.

Biochim Biophys Acta 2014 Sep 26;1842(9):1733-41. Epub 2014 Jun 26.

Department of Anatomy, Cardiovascular Research Institute, BK21 Plus Biomedical Convergence Program, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea. Electronic address:

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September 2014

Recruitment and subsequent proliferation of bone marrow-derived cells in the postischemic kidney are important to the progression of fibrosis.

Am J Physiol Renal Physiol 2014 Jun 16;306(12):F1451-61. Epub 2014 Apr 16.

Department of Anatomy and BK21 Plus Biomedical Convergence Program, Kyungpook National University School of Medicine, Daegu, Republic of Korea; Cardiovascular Research Institute, Kyungpook National University School of Medicine, Daegu, Republic of Korea; and

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June 2014

Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury.

Biochim Biophys Acta 2013 Dec 10;1832(12):1998-2008. Epub 2013 Jul 10.

Department of Anatomy, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea; Cardiovascular Research Institute, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea.

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December 2013

Involvement of hydrogen sulfide and homocysteine transsulfuration pathway in the progression of kidney fibrosis after ureteral obstruction.

Biochim Biophys Acta 2013 Dec 9;1832(12):1989-97. Epub 2013 Jul 9.

Department of Anatomy, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea.

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December 2013

Gender-specific role of HDAC11 in kidney ischemia- and reperfusion-induced PAI-1 expression and injury.

Am J Physiol Renal Physiol 2013 Jul 8;305(1):F61-70. Epub 2013 May 8.

Department of Anatomy and BK21, Kyungpook National University School of Medicine, Daegu, Republic of Korea.

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July 2013

Defect in Runx2 gene accelerates ureteral obstruction-induced kidney fibrosis via increased TGF-β signaling pathway.

Biochim Biophys Acta 2013 Oct 29;1832(10):1520-7. Epub 2013 Apr 29.

Department of Anatomy and BK21, Kyungpook National University School of Medicine, Republic of Korea.

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October 2013

Nuclear localization of CPI-17, a protein phosphatase-1 inhibitor protein, affects histone H3 phosphorylation and corresponds to proliferation of cancer and smooth muscle cells.

Biochem Biophys Res Commun 2013 Apr 26;434(1):137-42. Epub 2013 Mar 26.

Department of Molecular Physiology and Biophysics, and Kimmel Cancer Center, Thomas Jefferson University, 1020 Locust Street, PA 19107, USA.

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April 2013

Reduction of oxidative stress during recovery accelerates normalization of primary cilia length that is altered after ischemic injury in murine kidneys.

Am J Physiol Renal Physiol 2013 May 20;304(10):F1283-94. Epub 2013 Mar 20.

Department of Anatomy, Kyungpook National University School of Medicine, Daegu, Republic of Korea.

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May 2013

Bone marrow-derived cells play a major role in kidney fibrosis via proliferation and differentiation in the infiltrated site.

Biochim Biophys Acta 2013 Jun 4;1832(6):817-25. Epub 2013 Mar 4.

Department of Anatomy and Cardiovascular Research Institute, Kyungpook National University School of Medicine, 101 Dongindong, Jung-gu, Daegu, 700-422, South Korea.

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June 2013

Patient specific CFD models of nasal airflow: overview of methods and challenges.

J Biomech 2013 Jan 20;46(2):299-306. Epub 2012 Dec 20.

Department of Mechanical Engineering, Konkuk University, Seoul, Republic of Korea.

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January 2013

A collaborative molecular modeling environment using a virtual tunneling service.

J Biomed Biotechnol 2012 8;2012:546521. Epub 2012 Aug 8.

Department of Advanced Technology Fusion, Konkuk University, Seoul 143-701, Republic of Korea.

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November 2012

Probing regulatory proteins for vascular contraction by deoxyribonucleic Acid microarray.

Korean Circ J 2012 Jul 26;42(7):479-86. Epub 2012 Jul 26.

Department of Pharmacology, Kyungpook National University School of Medicine, Daegu, Korea.

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July 2012

Protective role of methionine sulfoxide reductase A against ischemia/reperfusion injury in mouse kidney and its involvement in the regulation of trans-sulfuration pathway.

Antioxid Redox Signal 2013 Jun 9;18(17):2241-50. Epub 2012 Jul 9.

Department of Anatomy, Kyungpook National University School of Medicine, Daegu, Republic of Korea.

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June 2013

Previous ischemia and reperfusion injury results in resistance of the kidney against subsequent ischemia and reperfusion insult in mice; a role for the Akt signal pathway.

Nephrol Dial Transplant 2012 Oct 3;27(10):3762-70. Epub 2012 May 3.

Department of Anatomy, Kyungpook National University School of Medicine, Dongindong, Junggu, Daegu, Korea.

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October 2012

Reciprocal regulation controlling the expression of CPI-17, a specific inhibitor protein for the myosin light chain phosphatase in vascular smooth muscle cells.

Am J Physiol Cell Physiol 2012 Jul 25;303(1):C58-68. Epub 2012 Apr 25.

Department of Molecular Physiology and Biophysics, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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July 2012

Bone marrow derived cells and reactive oxygen species in hypertrophy of contralateral kidney of transient unilateral renal ischemia-induced mouse.

Free Radic Res 2012 Jul 14;46(7):903-11. Epub 2012 May 14.

Department of Anatomy and BK 21 Project, Kyungpook National University School of Medicine, Daegu, Republic of Korea.

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July 2012

Orchiectomy attenuates kidney fibrosis after ureteral obstruction by reduction of oxidative stress in mice.

Am J Nephrol 2012 3;35(1):7-16. Epub 2011 Dec 3.

Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, South Korea.

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May 2012

Intra-renal slow cell-cycle cells contribute to the restoration of kidney tubules injured by ischemia/reperfusion.

Anat Cell Biol 2011 Sep 29;44(3):186-93. Epub 2011 Sep 29.

Department of Anatomy, Kyungpook National University School of Medicine, Daegu, Korea.

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September 2011

Protective role of cytosolic NADP(+)-dependent isocitrate dehydrogenase, IDH1, in ischemic pre-conditioned kidney in mice.

Free Radic Res 2011 Jul 21;45(7):759-66. Epub 2011 Apr 21.

Department of Anatomy and BK 21 Project, Kyungpook National University School of Medicine, Daegu, 700-422, Republic of Korea.

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July 2011

Endotoxin-induced renal tolerance against ischemia and reperfusion injury is removed by iNOS, but not eNOS, gene-deletion.

BMB Rep 2010 Sep;43(9):629-34

Department of Anatomy and BK21, Kyungpook National University School of Medicine, Daegu, Korea.

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September 2010

Heat shock augments angiotensin II-induced vascular contraction through increased production of reactive oxygen species.

Biochem Biophys Res Commun 2010 Aug 3;399(3):452-7. Epub 2010 Aug 3.

Department of Pharmacology and Cardiovascular Research Institute, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea.

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August 2010

Expression of CPI-17 in smooth muscle during embryonic development and in neointimal lesion formation.

Histochem Cell Biol 2009 Aug 13;132(2):191-8. Epub 2009 May 13.

Department of Molecular Physiology and Biophysics, Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA 19107, USA.

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August 2009

Vasorelaxation by Samhwangsasim-tang, an herb medicine, is associated with decreased phosphorylation of the myosin phosphatase target subunit.

Environ Toxicol Pharmacol 2007 Nov 24;24(3):199-205. Epub 2007 May 24.

Department of Pharmacology, Kyungpook National University School of Medicine, Daegu, 700-422, Republic of Korea.

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November 2007

Flavone inhibits vascular contraction by decreasing phosphorylation of the myosin phosphatase target subunit.

Clin Exp Pharmacol Physiol 2007 Nov;34(11):1116-20

Department of Pharmacology, Kyungpook National University School of Medicine, Daegu, Republic of Korea.

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November 2007

Identification of differentially expressed genes after heat shock in isolated rat aorta.

Clin Exp Pharmacol Physiol 2007 Jul;34(7):636-40

Department of Pharmacology, Kyungpook National University School of Medicine, Daegu, Korea.

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July 2007

Heat shock augments myosin phosphatase target-subunit phosphorylation.

Biochem Biophys Res Commun 2007 May 15;356(3):718-22. Epub 2007 Mar 15.

Department of Pharmacology, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea.

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May 2007

A role for Rho kinase in vascular contraction evoked by sodium fluoride.

Biochem Biophys Res Commun 2006 Apr 28;343(1):27-33. Epub 2006 Feb 28.

Department of Pharmacology, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea.

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April 2006

Heat shock-induced augmentation of vascular contractility is independent of rho-kinase.

Clin Exp Pharmacol Physiol 2006 Mar;33(3):264-8

Department of Pharmacology, Kyungpook National University School of Medicine, Daegu, Republic of Korea.

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March 2006

Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter.

J Biol Chem 2005 Oct 22;280(42):35579-87. Epub 2005 Aug 22.

Department of Biochemistry, School of Dentistry and Skeletal Diseases Genome Research Center, School of Medicine, Kyungpook National University, Daegu, Korea.

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October 2005

Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury.

J Biol Chem 2004 Dec 8;279(50):52282-92. Epub 2004 Sep 8.

Renal Division, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA.

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December 2004

Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney.

J Biol Chem 2003 Jul 7;278(29):27256-66. Epub 2003 Apr 7.

Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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July 2003