Jean-Sebastien Joyal

Jean-Sebastien Joyal

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Jean-Sebastien Joyal

Jean-Sebastien Joyal

Publications by authors named "Jean-Sebastien Joyal"

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42Publications

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Dyslipidemia in retinal metabolic disorders.

EMBO Mol Med 2019 Oct 5;11(10):e10473. Epub 2019 Sep 5.

Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.15252/emmm.201910473DOI Listing
October 2019

Should We Care About Pediatric Multiple Organ Dysfunction Syndrome?

Pediatr Crit Care Med 2019 Oct;20(10):987-988

Division of Pediatric Critical Care, Department of Pediatrics, CHU Sainte-Justine, University of Montreal, Montreal, QC, Canada.

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http://dx.doi.org/10.1097/PCC.0000000000002066DOI Listing
October 2019

Müller Cell-Localized G-Protein-Coupled Receptor 81 (Hydroxycarboxylic Acid Receptor 1) Regulates Inner Retinal Vasculature via Norrin/Wnt Pathways.

Am J Pathol 2019 Sep 18;189(9):1878-1896. Epub 2019 Jun 18.

Departments of Pediatrics, Ophthalmology and Pharmacology, Centre Hospitalier Universitaire Sainte-Justine Research Center, Montréal, Quebec, Canada; Department of Pharmacology and Therapeutics, McGill University, Montréal, Quebec, Canada; Department of Pharmacology, Université de Montréal, Montréal, Quebec, Canada; Research Center, Maisonneuve-Rosemont Hospital, Montréal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.05.016DOI Listing
September 2019

The Power of Rare: An Opportunity to Repurpose an Old Drug for Mitochondrial Cardiomyopathy.

Can J Cardiol 2018 08 27;34(8):950-952. Epub 2018 Apr 27.

Cardiovascular Genetics, CHU Sainte Justine Research Center, Department of Pediatrics, Université de Montréal, Montréal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2018.04.025DOI Listing
August 2018

Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism.

Prog Retin Eye Res 2018 05 22;64:131-156. Epub 2017 Nov 22.

Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, 300 Longwood Avenue, Boston MA 02115, United States. Electronic address:

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http://dx.doi.org/10.1016/j.preteyeres.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963988PMC
May 2018

Multiple organ dysfunction syndrome in critically ill children: clinical value of two lists of diagnostic criteria.

Ann Intensive Care 2016 Dec 29;6(1):40. Epub 2016 Apr 29.

Division of Pediatric Critical Care, Department of Pediatrics, Sainte-Justine Hospital, CHU Sainte-Justine, Room 3431, 3175 Chemin de la Côte-Ste-Catherine, Montreal, QC, H3T 1C5, Canada.

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http://dx.doi.org/10.1186/s13613-016-0144-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851677PMC
December 2016

SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth.

Sci Signal 2015 Sep 22;8(395):ra94. Epub 2015 Sep 22.

Department of Ophthalmology, Harvard Medical School, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scisignal.aaa8695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659437PMC
September 2015

Subcellular G-protein coupled receptor signaling hints at greater therapeutic selectivity.

Expert Opin Ther Targets 2015 Jun;19(6):717-21

Université de Montréal, CHU Ste-Justine Hospital Research Centre, Departments of Pediatrics, Ophthalmology and Pharmacology , 3175 Côte Ste-Catherine, Montréal, Qc, H3T 1C5 , Canada +1 514 345 4931 Ext. 2978 ; +1 514 345 4801 ; ;

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http://dx.doi.org/10.1517/14728222.2015.1042365DOI Listing
June 2015

Dietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin.

Am J Clin Nutr 2015 Apr 4;101(4):879-88. Epub 2015 Feb 4.

From the Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA (ZF, ZS, YS, J-SJ, CGH, RZC, LPE, KT, JC, and LEHS); the Department of Ophthalmology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden (CAL and AH); the Department of Pediatrics, Institute of Clinical Sciences Lund, Lund University and Skåne University Hospital, Lund, Sweden (DL and IHP); and National Eye Institute, Division of Epidemiology and Clinical Research Clinical Trials Branch, National Eye Institute, NIH, Bethesda, MD (JPS).

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http://dx.doi.org/10.3945/ajcn.114.099291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381778PMC
April 2015

Retinal neurons curb inflammation and enhance revascularization in ischemic retinopathies via proteinase-activated receptor-2.

Am J Pathol 2015 Feb 3;185(2):581-95. Epub 2014 Dec 3.

Department of Pharmacology, CHU Sainte-Justine Hospital, University of Montréal, Montréal, Québec, Canada; Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Center, University of Montréal, Montréal, Québec, Canada; Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada; Department of Pediatrics, CHU Sainte-Justine Hospital, University of Montréal, Montréal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.10.020DOI Listing
February 2015

Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis.

Nat Med 2014 Oct 14;20(10):1165-73. Epub 2014 Sep 14.

1] Department of Pediatrics, Centre Hospitalier Universitaire (CHU) Sainte-Justine Research Center, Université de Montréal, Montréal, Québec, Canada. [2] Department of Ophthalmology, Hôpital Maisonneuve-Rosemont Research Center, Université de Montreal, Montreal, Québec, Canada. [3] Department of Pharmacology, Université de Montréal, Montréal, Québec, Canada. [4] Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1038/nm.3669DOI Listing
October 2014

Management of neonatal sepsis in term newborns.

F1000Prime Rep 2014 1;6:67. Epub 2014 Aug 1.

Division of Pediatric Critical Care Medicine, Department of Pediatrics, Université de Montréal and Sainte-Justine Hospital 3175 Cote Sainte-Catherine, Montreal Canada H3T1C5.

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http://dx.doi.org/10.12703/P6-67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126544PMC
August 2014

Cytochrome P450 2C8 ω3-long-chain polyunsaturated fatty acid metabolites increase mouse retinal pathologic neovascularization--brief report.

Arterioscler Thromb Vasc Biol 2014 Mar 23;34(3):581-6. Epub 2014 Jan 23.

From the Department of Ophthalmology, Boston Children's Hospital (Z.S., Z.F., J.-S.J., C. Hatton, A.J., C. Hurst, L.E., Z.C., D.P., Y.G., D.X., K.T., H.B., J.C., L.E.H.S.) and Department of Pathology, Beth Israel Deaconess Medical Center (D.P.), Harvard Medical School, Boston, MA; University Eye Hospital Freiburg, Freiburg, Germany (A.S.); Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, NC (M.L.E., F.L., D.C.Z.); Department of Ophthalmology, Hôpital Maisonneuve-Rosemont, University of Montreal, Montreal, Quebec, Canada (P.S.); and Department of Ophthalmology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden (A.H.).

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http://dx.doi.org/10.1161/ATVBAHA.113.302927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005334PMC
March 2014

Microglia and interleukin-1β in ischemic retinopathy elicit microvascular degeneration through neuronal semaphorin-3A.

Arterioscler Thromb Vasc Biol 2013 Aug 13;33(8):1881-91. Epub 2013 Jun 13.

Department of Pediatrics, Ophthalmology, and Pharmacology, CHU Sainte-Justine Research Center, Paris, France.

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http://dx.doi.org/10.1161/ATVBAHA.113.301331DOI Listing
August 2013

Neovascularization in retinopathy of prematurity: opposing actions of neuronal factors GPR91 and semaphorins 3A.

Acta Paediatr 2012 Aug 5;101(8):819-26. Epub 2012 May 5.

Departments of Pediatrics, Ophthalmology, and Pharmacology, Centre Hospitalier Universitaire Ste-Justine Research Center, Montréal, QC, Canada.

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http://dx.doi.org/10.1111/j.1651-2227.2012.02692.xDOI Listing
August 2012

Understanding retinopathy of prematurity: update on pathogenesis.

Neonatology 2011 3;100(4):343-53. Epub 2011 Oct 3.

Department of Pediatrics, Ophthalmology and Pharmacology, Centre Hospitalier Universitaire Sainte-Justine Research Center, Montréal, Qué., Canada.

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http://dx.doi.org/10.1159/000330174DOI Listing
March 2012

Choroidal involution is a key component of oxygen-induced retinopathy.

Invest Ophthalmol Vis Sci 2011 Aug 5;52(9):6238-48. Epub 2011 Aug 5.

Department of Ophthalmology and Pharmacology, Hôpital Sainte-Justine Research Center, Montreal, Canada.

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http://dx.doi.org/10.1167/iovs.10-6742DOI Listing
August 2011

Cortactin activation by FVIIa/tissue factor and PAR2 promotes endothelial cell migration.

Am J Physiol Regul Integr Comp Physiol 2011 Mar 15;300(3):R577-85. Epub 2010 Dec 15.

Department of Pediatrics, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Quebec, Canada.

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http://dx.doi.org/10.1152/ajpregu.00137.2010DOI Listing
March 2011

Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life.

J Clin Invest 2010 Sep 1;120(9):3022-32. Epub 2010 Sep 1.

Department of Ophthalmology, Children’s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI42142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929716PMC
September 2010

Proliferative retinopathies: angiogenesis that blinds.

Int J Biochem Cell Biol 2010 Jan 15;42(1):5-12. Epub 2009 Oct 15.

Department of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.biocel.2009.10.006DOI Listing
January 2010

The pediatric multiple organ dysfunction syndrome.

Pediatr Crit Care Med 2009 Jan;10(1):12-22

Division of Critical Care Medicine, Department of Pediatrics, Sainte-Justine Hospital, University of Montreal, Montreal, Canada.

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http://dx.doi.org/10.1097/PCC.0b013e31819370a9DOI Listing
January 2009

Intracellular-specific colocalization of prostaglandin E2 synthases and cyclooxygenases in the brain.

Am J Physiol Regul Integr Comp Physiol 2004 Nov 29;287(5):R1155-63. Epub 2004 Jul 29.

Deptartment of Pediatrics, Research Center of Hôpital Sainte-Justine, 3175, Côte Sainte-Catherine, Montréal, Québec, Canada H3T 1C5.

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http://dx.doi.org/10.1152/ajpregu.00077.2004DOI Listing
November 2004

Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity.

Am J Physiol Regul Integr Comp Physiol 2003 Apr;284(4):R928-35

Centre de Recherche de l'Hôpital Sainte-Justine, Department of Pediatrics and Pharmacology, Université de Montréal, Montréal, H3T 1C5.

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http://dx.doi.org/10.1152/ajpregu.00633.2002DOI Listing
April 2003