Jean-Sebastien Hulot

Jean-Sebastien Hulot

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Jean-Sebastien Hulot

Publications by authors named "Jean-Sebastien Hulot"

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Association of Oral Contraceptives With Drug-Induced QT Interval Prolongation in Healthy Nonmenopausal Women.

JAMA Cardiol 2018 Sep;3(9):877-882

Centres d'Investigation Clinique Paris-Est, Assistance Publique des Hôpitaux de Paris, Department of Pharmacology, Pitié-Salpêtrière Hospital, Paris, France.

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http://cardiology.jamanetwork.com/article.aspx?doi=10.1001/j
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http://dx.doi.org/10.1001/jamacardio.2018.2251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233640PMC
September 2018

Opioid-related genetic polymorphisms do not influence postoperative opioid requirement: A prospective observational study.

Eur J Anaesthesiol 2018 07;35(7):496-504

From the Department of Anaesthesiology and Intensive Care, Croix-Rousse Hospital (CHU), Hospices Civils de Lyon (HCL), HESPER 7425, Claude Bernard Lyon 1 University, Lyon (FA); Sorbonne Université (OL, LB, FK, J-SH, BR), UMRS INSERM 1166, IHU ICAN, Paris, France; Assistance Publique-Hôpitaux de Paris (APHP), Department of Anaesthesiology and Critical Care (OL, NB), Department of Pharmacology (NZ, J-SH), Department of Biostatistics (NC, LB), Department of Orthopaedic Surgery (FK) and Department of Emergency Medicine and Surgery (BR), Groupe Hospitalier Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1097/EJA.0000000000000793DOI Listing
July 2018

CRISPRed Cardiomyocytes to Decrypt Variants of Uncertain Significance.

J Am Coll Cardiol 2018 Jul;72(1):76-78

INSERM, UMR_S 970, Paris Cardiovascular Research Center (PARCC), Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183471
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http://dx.doi.org/10.1016/j.jacc.2018.05.004DOI Listing
July 2018

Reg3β is associated with cardiac inflammation and provides prognostic information in patients with acute coronary syndrome.

Int J Cardiol 2018 05;258:7-13

Department of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany; Department of Cardiac Surgery, Schüchtermann-Clinic, Bad Rothenfelde, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.01.043DOI Listing
May 2018

Outcome after revascularisation of acute myocardial infarction with cardiogenic shock on extracorporeal life support.

EuroIntervention 2018 04 6;13(18):e2160-e2168. Epub 2018 Apr 6.

Sorbonne Université, ACTION Study Group, INSERM UMR_S 1166, Institut de Cardiologie, Département de Cardiologie, Pitié-Salpêtrière Hospital (AP-HP), Paris, France.

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http://www.pcronline.com/eurointervention/133rd_issue/357
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http://dx.doi.org/10.4244/EIJ-D-17-01014DOI Listing
April 2018

Perivascular fibrosis and the microvasculature of the heart. Still hidden secrets of pathophysiology?

Vascul Pharmacol 2018 Apr 27. Epub 2018 Apr 27.

Center of Aging Sciences and Translational Medicine - CESI-MeT, Institute of Cardiology, "G. d'Annunzio" University, Chieti, Italy; The Texas Heart Institute and Center for Cardiovascular Biology and Atherosclerosis Research, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.vph.2018.04.007DOI Listing
April 2018

Complex Association of Sex Hormones on Left Ventricular Systolic Function: Insight into Sexual Dimorphism.

J Am Soc Echocardiogr 2018 Feb 13;31(2):231-240.e1. Epub 2017 Dec 13.

Sorbonne Universités, UPMC Univ Paris 06, AP-HP, Pitié-Salpêtrière Hospital, Department of Cardiology, Echocardiography Unit, Paris, France; UMR ICAN 1166, Paris, France.

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http://dx.doi.org/10.1016/j.echo.2017.10.017DOI Listing
February 2018

Effectiveness of heart rate control on hemodynamics in critically ill patients with atrial tachyarrhythmias managed by amiodarone.

Pharmacol Res 2017 Aug 10;122:118-126. Epub 2017 Jun 10.

AP-HP, Pitié-Salpêtrière Hospital, Department of Pharmacology and CIC-1421, F-75013 Paris, France; INSERM, CIC-1421 and UMR ICAN 1166, F-75013 Paris, France; Sorbonne Universités, UPMC Univ Paris 06, Faculty of Medicine, Department of Pharmacology and UMR ICAN 1166, F-75013 Paris, France; Institute of Cardiometabolism and Nutrition (ICAN), France; CIC-1419 INSERM, EAU-08 University Paris Descartes Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1016/j.phrs.2017.06.004DOI Listing
August 2017

Fibrogenic Potential of PW1/Peg3 Expressing Cardiac Stem Cells.

J Am Coll Cardiol 2017 Aug;70(6):728-741

Sorbonne-Universités, Université Pierre-et-Marie-Curie (UPMC), INSERM UMRS_1166, Institute of Cardiometabolism and Nutrition, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.06.010DOI Listing
August 2017

Impact of negative inotropic drugs on accuracy of diastolic stress echocardiography for evaluation of left ventricular filling pressure.

Sci Rep 2017 Aug 25;7(1):9537. Epub 2017 Aug 25.

Sorbonne Universités, UPMC Univ Paris 06, AP-HP, CIC 1421, CIC-Paris Est, Cardiology department-Echocardiography Unit, Pharmacology department, INSERM-U1166 ICAN, Pitié-Salpêtrière Hospital, F-75013, Paris, France.

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http://dx.doi.org/10.1038/s41598-017-10301-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573383PMC
August 2017

Platelet reactivity in human immunodeficiency virus infected patients on dual antiplatelet therapy for an acute coronary syndrome: the EVERE2ST-HIV study.

Eur Heart J 2017 Jun;38(21):1676-1686

Sorbonne Université - Univ Paris 06 (UPMC), ACTION Study Group, INSERM UMR_S 1166, ICAN, Institut de Cardiologie, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France.

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http://dx.doi.org/10.1093/eurheartj/ehw583DOI Listing
June 2017

Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells.

Diabetes 2017 06 7;66(6):1470-1478. Epub 2017 Mar 7.

Sorbonne Universités, Université Pierre et Marie Curie, INSERM UMR_S938, Centre de Recherche Saint-Antoine, Institute of Cardiometabolism and Nutrition, Paris, France.

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http://dx.doi.org/10.2337/db16-1107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440013PMC
June 2017

Get Your Cell K.O. in the First Round.

Circ Res 2017 May;120(10):1522-1523

From the Sorbonne Universités, UPMC Univ Paris 06, AP-HP, Institute of Cardiometabolism and Nutrition, France.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.310955DOI Listing
May 2017

In Vitro Adherence Defines Therapeutic Cardiac Mesenchymal Cell Subpopulation.

J Am Coll Cardiol 2017 Apr;69(14):1839-1841

Sorbonne Universités, UPMC University Paris 06, AP-HP, Institute of Cardiometabolism and Nutrition (ICAN), Pitié-Salpêtrière Hospital, Paris, France.

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http://dx.doi.org/10.1016/j.jacc.2017.02.013DOI Listing
April 2017

A PDGFRα-Mediated Switch toward CD9 Adipocyte Progenitors Controls Obesity-Induced Adipose Tissue Fibrosis.

Cell Metab 2017 03 16;25(3):673-685. Epub 2017 Feb 16.

Institute of Cardiometabolism and Nutrition, ICAN, Pitié-Salpêtrière Hospital, F-75013 Paris, France; INSERM, UMRS 1166 (teams 2, 4, and 6 NutriOmics), F-75013 Paris, France; Assistance Publique Hopitaux de Paris, AP-HP, Pitié-Salpêtrière Hospital, Nutrition and Endocrinology Department and Hepato-biliary and Digestive Surgery Department, F-75013 Paris, France; Sorbonne Universités, UPMC Univ Paris 06, UMRS 1166, F-75013 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.01.010DOI Listing
March 2017

Genomic correction of familial cardiomyopathy in human engineered cardiac tissues.

Eur Heart J 2016 11 22;37(43):3282-3284. Epub 2016 Jul 22.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, PO Box 1030, New York, NY 10029, USA.

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http://dx.doi.org/10.1093/eurheartj/ehw307DOI Listing
November 2016

Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients with Atrial Tachyarrhythmias.

Clin Pharmacokinet 2016 08;55(8):991-1002

Centre d'Investigation Clinique-1419 INSERM, EAU-08 Université Paris Descartes Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1007/s40262-016-0372-9DOI Listing
August 2016

Gene therapy for the treatment of heart failure: promise postponed.

Eur Heart J 2016 06 27;37(21):1651-8. Epub 2016 Feb 27.

Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1030, New York, NY 10029-6574, USA

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http://dx.doi.org/10.1093/eurheartj/ehw019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887702PMC
June 2016

The pharmacogenetic control of antiplatelet response: candidate genes and CYP2C19.

Expert Opin Drug Metab Toxicol 2015 14;11(10):1599-617. Epub 2015 Jul 14.

a 1 Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences , New York, NY, USA +1 212 241 3780 ; +1 212 241 0139 ;

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http://dx.doi.org/10.1517/17425255.2015.1068757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829114PMC
May 2016

MRP4 (ABCC4) as a potential pharmacologic target for cardiovascular disease.

Pharmacol Res 2016 05 5;107:381-389. Epub 2016 Apr 5.

Inserm UMR-S1140, Faculté de Pharmacie, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2016.04.002DOI Listing
May 2016

Generating patient-specific induced pluripotent stem cells-derived cardiomyocytes for the treatment of cardiac diseases.

Expert Opin Biol Ther 2015 2;15(10):1399-409. Epub 2015 Jul 2.

b 2 Icahn School of Medicine at Mount Sinai, Cardiovascular Research Center , New York, NY, USA

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http://dx.doi.org/10.1517/14712598.2015.1064109DOI Listing
April 2016

miR-322 regulates insulin signaling pathway and protects against metabolic syndrome-induced cardiac dysfunction in mice.

Biochim Biophys Acta 2016 04 13;1862(4):611-621. Epub 2016 Jan 13.

Institute for Cardiometabolism and Nutrition (ICAN), Paris F-75013, France; INSERM UMR-S 1166, Paris F-75013, France; Sorbonne Universités, Université Pierre et Marie Curie -UPMC Univ Paris 06, UMR-S 1166, Paris F-75013, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2016.01.010DOI Listing
April 2016

Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling.

Circulation 2016 Apr 2;133(15):1458-71; discussion 1471. Epub 2016 Mar 2.

From Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY (L.B., J.G.O., M.C., A.L., M.N., D.S.M., E.K., C.W.K., R.J.H., J.-S.H.); and Sorbonne Universités, UPMC Univ Paris 06, AP-HP, Institute of Cardiometabolism and Nutrition (ICAN), Pitié-Salpêtrière Hospital, Paris, France (C.P., J.-S.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829441PMC
April 2016

Resident PW1+ Progenitor Cells Participate in Vascular Remodeling During Pulmonary Arterial Hypertension.

Circ Res 2016 Mar 12;118(5):822-33. Epub 2016 Jan 12.

From the INSERM, Institute of Cardiometabolism and Nutrition, UMR_S 1166-ICAN (F.D., T.H., V.M., C.C., V.B., E.Y.-G., J.-S.H., G.M., D.S., F.S., S.N.), UMS-030 CyPS, Paris, France (B.H.-C.), PECMV UMS28 (N.M.), INSERM, CNRS, CR7, Centre d'Immunologie et des Maladies Infectieuses (CIMI), U1135, ERL 8255 (G.M.), Sorbonne Universités, UPMC Univ Paris 06, Paris, France; Erasmus MC Stem Cell Institute, Rotterdam, The Netherlands (M.C.); Univ Paris-Sud, Université Paris Saclay, INSERM UMR-S 999, Labex LERMIT, Le Plessis-Robinson, Paris, France (P.D., E.F., M.H.); Service d'Anatomie Pathologique, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson, Paris, France (P.D.); Service de Chirurgie Thoracique et Vasculaire, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson, France (E.F.); Univ Paris-Sud, Université Paris Saclay, Le Kremlin-Bicêtre, Paris, France (M.H.); and Assistance Publique Hôpitaux de Paris, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, Hôpital Bicêtre, Le Kremlin Bicêtre, France (M.H.).

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http://circres.ahajournals.org/content/118/5/822.full.pdf
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http://circres.ahajournals.org/lookup/doi/10.1161/CIRCRESAHA
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http://dx.doi.org/10.1161/CIRCRESAHA.115.307035DOI Listing
March 2016

Intravenous Clopidogrel (MDCO-157) Compared with Oral Clopidogrel: The Randomized Cross-Over AMPHORE Study.

Am J Cardiovasc Drugs 2016 Feb;16(1):43-53

Institut de Cardiologie, INSERM_UMRS 1166, Pitié-Salpêtrière Hospital (AP-HP), Sorbonne Universités UPMC (Paris 6), Paris, France.

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http://dx.doi.org/10.1007/s40256-015-0145-0DOI Listing
February 2016

Point-of-care genetic profiling and/or platelet function testing in acute coronary syndrome.

Thromb Haemost 2016 Jan 1;115(2):382-91. Epub 2015 Oct 1.

Gilles Montalescot, MD, PhD, Institut de Cardiologie, Bureau 2-236, Pitié-Salpêtrière Hospital, 47 Boulevard de l'Hôpital, 75013 Paris, France, Tel.:+33 1 4216 3006, Fax:+33 1 4216 2931, E-mail:

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http://dx.doi.org/10.1160/TH15-05-0394DOI Listing
January 2016

Clopidogrel and CYP2C19: pharmacogenetic testing ready for clinical prime time?

Clin Chem 2015 Oct 13;61(10):1235-40. Epub 2015 Aug 13.

Program Director, Adult Interventional Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1373/clinchem.2015.238105DOI Listing
October 2015

Impaired platelet activation and cAMP homeostasis in MRP4-deficient mice.

Blood 2015 Oct 27;126(15):1823-30. Epub 2015 Aug 27.

INSERM Unité Mixte de Recherche S1140, Faculté de Pharmacie, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service d'Hématologie Biologique, Paris, France;

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http://www.bloodjournal.org/content/bloodjournal/early/2015/
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2015-02-63
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http://dx.doi.org/10.1182/blood-2015-02-631044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626663PMC
October 2015

Omeprazole, pantoprazole, and CYP2C19 effects on clopidogrel pharmacokinetic-pharmacodynamic relationships in stable coronary artery disease patients.

Eur J Clin Pharmacol 2015 Sep 14;71(9):1059-66. Epub 2015 Jun 14.

Aix-Marseille Université, INSERM, UMR912 (SESSTIM), 13003, Marseille, France,

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http://dx.doi.org/10.1007/s00228-015-1882-3DOI Listing
September 2015

Inhalable delivery of AAV-based MRP4/ABCC4 silencing RNA prevents monocrotaline-induced pulmonary hypertension.

Mol Ther Methods Clin Dev 2015 4;2:14065. Epub 2015 Feb 4.

Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1166, ICAN , Paris, France ; INSERM, UMR_S 1166, ICAN , Paris, France ; AP-HP, Hôpital Pitié-Salpêtrière, Department of Pharmacology & Institute of CardioMetabolism and Nutrition , Paris, France.

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http://dx.doi.org/10.1038/mtm.2014.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449024PMC
June 2015

Emergence of Orai3 activity during cardiac hypertrophy.

Cardiovasc Res 2015 Mar 11;105(3):248-59. Epub 2014 Sep 11.

Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1166, ICAN, F-75005 Paris, France INSERM, UMR_S 1166, ICAN, F-75005 Paris, France

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http://dx.doi.org/10.1093/cvr/cvu207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351368PMC
March 2015

Development and validation of a rapid and simple LC-MS/MS method for quantification of vemurafenib in human plasma: application to a human pharmacokinetic study.

Ther Drug Monit 2015 Feb;37(1):132-6

Departments of *Pharmacology and CIC-1421, and †Pharmacy, Pitié-Salpêtrière Hospital, AP-HP; ‡Department of Pharmacology and UMR ICAN 1166, Faculty of Medicine, Sorbonne University, UPMC Univ Paris 06; and §INSERM, CIC-1421, and UMR ICAN 1166, Paris, France.

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http://pdfs.journals.lww.com/drug-monitoring/2015/02000/Deve
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FTD.0000000000000110DOI Listing
February 2015

Pharmacology and mechanisms of action of new oral anticoagulants.

Fundam Clin Pharmacol 2015 Feb 25;29(1):10-20. Epub 2014 Sep 25.

Department of Pharmacology and UMR ICAN 1166, Faculty of Medicine, Institute of Cardiometabolism and Nutrition (ICAN), Sorbonne Universités, UPMC Univ Paris 06, F-75013, Paris, France; Department of Pharmacology and CIC-1421, Institute of Cardiometabolism and Nutrition (ICAN), AP-HP, Pitié-Salpêtrière Hospital, F-75013, Paris, France; INSERM, Institute of Cardiometabolism and Nutrition (ICAN), CIC-1421 and UMR ICAN 1166, F-75013, Paris, France.

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http://dx.doi.org/10.1111/fcp.12091DOI Listing
February 2015

Overexpression of cyclic adenosine monophosphate effluent protein MRP4 induces an altered response to β-adrenergic stimulation in the senescent rat heart.

Anesthesiology 2015 Feb;122(2):334-42

From the Sorbonne Universités UPMC Univ Paris 06, UMR INSERM-UPMC 1166, Paris, France (A.C., S.F., C.J., F.A., N.M., J.-S.H., B.R., J.A.); Department of Anesthesiology and Critical Care Medicine (A.C., J.A.), Department of Emergency Medicine and Surgery (N.N., B.R.), and Department of Pharmacology (J.-S.H.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Paris, France; Université de Reims Champagne-Ardenne and Department of Anesthesiology and Critical Care Medicine, Robert Debré Hospital, Reims, France (A.C.); Wuhan University, Wuhan, The People's Republic of China (C.J.); UMR INSERM 902 Université Evry Val d'Essone, Evry, France (S.B.); and Université Paris-Descartes, Paris, France (S.B.).

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http://dx.doi.org/10.1097/ALN.0000000000000526DOI Listing
February 2015

Impact of inodilator drugs on echocardiographic assessments of left ventricular filling pressure in patients with decompensated end-stage heart failure*.

Crit Care Med 2014 Dec;42(12):2508-17

1Reanimation and Cardiology, AP-HP, Georges Pompidou European Hospital, Paris, France. 2INSERM UPMC UMRS 1166, ICAN, Université Pierre et Marie Curie, Paris, France. 3Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, Ruhr-University of Bochum, Bad Oeynhausen, Germany. 4INSERM UMR-S 678, Laboratoire d'imagerie fonctionnelle, Université Pierre et Marie Curie, Paris, France. 5Faculty of Medicine, University Paris Descartes, Paris, France.

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http://pdfs.journals.lww.com/ccmjournal/2014/12000/Impact_of
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http://dx.doi.org/10.1097/CCM.0000000000000513DOI Listing
December 2014

Simultaneous determination of rivaroxaban and dabigatran levels in human plasma by high-performance liquid chromatography-tandem mass spectrometry.

J Pharm Biomed Anal 2014 Nov 15;100:230-235. Epub 2014 Aug 15.

AP-HP, Pitié-Salpêtrière Hospital, Department of Pharmacology and CIC-1421, F-75013 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2014.08.011DOI Listing
November 2014

Prasugrel but not high dose clopidogrel overcomes the lansoprazole neutralizing effect of P2Y12 inhibition: Results of the randomized DOSAPI study.

Eur J Clin Pharmacol 2014 Sep 12;70(9):1049-57. Epub 2014 Jul 12.

ACTION Study Group, Hôpital Pitié-Salpêtrière (APHP), Institut de Cardiologie, INSERM, UMR_S 1166, Pitié-Salpêtrière Hospital (AP-HP), Université Pierre et Marie Curie (UPMC Paris 6), 75013, Paris, France.

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http://dx.doi.org/10.1007/s00228-014-1710-1DOI Listing
September 2014

Urinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance.

Br J Clin Pharmacol 2014 Aug;78(2):329-42

Laboratoire de Biochimie et Biologie Moléculaire, CHRU de Tours, Tours, France; Université François Rabelais de Tours, PRES Centre Val de Loire Université, EA4245, Tours, France.

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http://doi.wiley.com/10.1111/bcp.12326
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http://dx.doi.org/10.1111/bcp.12326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137825PMC
August 2014

Modeling CVD in human pluripotent cells by genome editing.

J Am Coll Cardiol 2014 Aug;64(5):460-2

UMR S 1166 ICAN, Sorbonne Universités, Paris, France.

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http://dx.doi.org/10.1016/j.jacc.2014.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724803PMC
August 2014

Pulmonary hypertension: novel pathways and emerging therapies inhibitors of cGMP and cAMP metabolism.

Handb Exp Pharmacol 2013 ;218:513-29

INSERM/Université Pierre et Marie Curie UMRS 956, Paris, France.

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http://dx.doi.org/10.1007/978-3-642-38664-0_20DOI Listing
July 2014

Antiplatelet and anticoagulation therapy for acute coronary syndromes.

Circ Res 2014 Jun;114(12):1929-43

From the Brigham and Women's Hospital and Harvard Medical School, Boston, MA (D.L.B.); Icahn School of Medicine at Mount Sinai, Cardiovascular Research Institute, New York, NY (J.-S.H.); Department of Medicine and Gill Heart Institute, University of Kentucky, Lexington (D.J.M.); and Stanford University, CA (R.A.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.114.302737DOI Listing
June 2014

Clustering of acute and subacute stent thrombosis related to the introduction of generic clopidogrel.

J Cardiovasc Pharmacol Ther 2014 Mar 22;19(2):201-8. Epub 2013 Nov 22.

1Cardiology Department, Catheterization Laboratory, Mount Sinai Medical Center and Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1177/1074248413510605DOI Listing
March 2014

Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium.

FASEB J 2014 Feb 30;28(2):644-54. Epub 2013 Oct 30.

2Cardiovascular Cell and Tissue Engineering Laboratory, Cardiovascular Research Center, Icahn School of Medicine at Mt. Sinai, One Gustave L. Levy Pl., P.O. Box 1030, New York, NY 10029, USA.

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http://dx.doi.org/10.1096/fj.13-228007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898643PMC
February 2014

Antiplatelet drug interactions with proton pump inhibitors.

Expert Opin Drug Metab Toxicol 2014 Feb 9;10(2):175-89. Epub 2013 Nov 9.

Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences , One Gustave L. Levy Place, Box 1497, New York, NY 10029 , USA +1 212 241 3780 ; +1 212 241 0139 ;

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http://dx.doi.org/10.1517/17425255.2014.856883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110685PMC
February 2014

Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes.

Stem Cells Transl Med 2014 Jan 9;3(1):18-31. Epub 2013 Dec 9.

Cardiovascular Research Center and Department of Pharmacology and Systems Therapeutics, Systems Biology Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Stem Cell and Regenerative Medicine Consortium, Department of Physiology, LKS Faculty of Medicine, University of Hong Kong, Hong Kong.

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http://doi.wiley.com/10.5966/sctm.2013-0110
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http://dx.doi.org/10.5966/sctm.2013-0110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902291PMC
January 2014

An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.

J Mol Diagn 2013 Nov 5;15(6):783-9. Epub 2013 Sep 5.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2013.06.004DOI Listing
November 2013

2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology.

Eur Heart J 2013 Oct 30;34(38):2949-3003. Epub 2013 Aug 30.

The disclosure forms of the authors and reviewers are available on the ESC website www.escardio.org/guidelines.

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https://www.escardio.org/static_file/Escardio/Guidelines/pub
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http://eurheartj.oxfordjournals.org/lookup/doi/10.1093/eurhe
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http://dx.doi.org/10.1093/eurheartj/eht296DOI Listing
October 2013

Pharmacogenetics of clopidogrel.

Curr Pharm Des 2012 ;18(33):5309-27

Institut de Cardiologie, INSERM U 937, Groupe A.C.T.I.O.N. Groupe Hospitalier Pitié-Salpêtrière, 47, boulevard de l'Hôpital, 75013 Paris, France.

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April 2013

STIM1 and Orai in cardiac hypertrophy and vascular proliferative diseases.

Front Biosci (Schol Ed) 2013 Jan 1;5:766-73. Epub 2013 Jan 1.

Inserm UMRS 956, Faculte de Médecine Pitie-salpetriere, Paris, France.

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January 2013

Blockbuster interactions: are they bad for the patient?

Eur Heart J 2012 Sep 21;33(17):2121-3. Epub 2012 May 21.

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http://dx.doi.org/10.1093/eurheartj/ehs126DOI Listing
September 2012

High on-thienopyridine platelet reactivity in elderly coronary patients: the SENIOR-PLATELET study.

Eur Heart J 2012 May 7;33(10):1241-9. Epub 2011 Nov 7.

Bureau 236, Institut de Cardiologie, INSERM UMRS937, Pitié-Salpêtrière Hospital (AP-HP), Université Paris 6, 47-83 boulevard de l'Hôpital, Paris, France.

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http://dx.doi.org/10.1093/eurheartj/ehr407DOI Listing
May 2012

Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes.

FASEB J 2012 Mar 16;26(3):1009-17. Epub 2011 Nov 16.

Institut National de la Sante et de la Recherche Medicale (INSERM)/Universite Pierre et Marie Curie, Unite Mixte de Recherche en Sante (UMRS) 956, Paris, France.

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http://dx.doi.org/10.1096/fj.11-194027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289499PMC
March 2012

PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19.

Pharmacogenet Genomics 2012 Feb;22(2):159-65

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32834d4962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349992PMC
February 2012

Clopidogrel and CYP2C19 testing: ready for clinical prime time?

Clin Chem 2012 Jan 22;58(1):154-7. Epub 2011 Sep 22.

Cardiovascular Research Center, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1373/clinchem.2011.165829DOI Listing
January 2012

Thienopyridine-associated drug-drug interactions: pharmacologic mechanisms and clinical relevance.

Curr Cardiol Rep 2011 Oct;13(5):451-8

Cardiovascular Research Center, Mount Sinai School of Medicine, New York, NY, USA.

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http://link.springer.com/10.1007/s11886-011-0206-1
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October 2011

CYP2C19 but not PON1 genetic variants influence clopidogrel pharmacokinetics, pharmacodynamics, and clinical efficacy in post-myocardial infarction patients.

Circ Cardiovasc Interv 2011 Oct 4;4(5):422-8. Epub 2011 Oct 4.

Université Pierre et Marie Curie-Paris 6, INSERM UMR S 956, Pharmacology Department, Pitié-Salpêtrière University Hospital, Paris, France.

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.111.963025DOI Listing
October 2011

High doses of clopidogrel to overcome genetic resistance: the randomized crossover CLOVIS-2 (Clopidogrel and Response Variability Investigation Study 2).

JACC Cardiovasc Interv 2011 Apr;4(4):392-402

Institut de Cardiologie, INSERM CMR937, Hôpital Pitié-Salpêtrière (Assistance Publique-Hôpitaux de Paris), Université Pierre et Marie Curie (UPMC, Paris VI), Paris, France.

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http://dx.doi.org/10.1016/j.jcin.2011.03.002DOI Listing
April 2011

Genetic substudy of the PLATO trial.

Lancet 2011 Feb;377(9766):637, author reply 637-8

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http://dx.doi.org/10.1016/S0140-6736(11)60227-4DOI Listing
February 2011

Pharmacogenomics and personalized medicine: lost in translation?

Genome Med 2010 Feb 22;2(2):13. Epub 2010 Feb 22.

Cardiovascular Research Center, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1030, New York, NY 10029, USA.

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http://dx.doi.org/10.1186/gm134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847704PMC
February 2010

Stent thrombosis: who's guilty?

Eur Heart J 2009 Nov 23;30(22):2685-8. Epub 2009 Oct 23.

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http://dx.doi.org/10.1093/eurheartj/ehp436DOI Listing
November 2009

Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.

PLoS One 2009 Sep 22;4(9):e7114. Epub 2009 Sep 22.

MRC Centre for Neurodegeneration Research, King's College London, Department of Clinical Neuroscience, Institute of Psychiatry, and NIHR Biomedical Research Centre, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007114PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743996PMC
September 2009

Therapeutic drug monitoring of clozapine in a hemodialysed smoking patient with schizophrenia.

Ther Drug Monit 2009 Jun;31(3):281-2

Service de Pharmacologie, AP-HP, Hôpital Pitié-Salpêtrière, 75651 Paris Cedex 13, France.

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http://dx.doi.org/10.1097/FTD.0b013e3181a1c856DOI Listing
June 2009

Can we override clopidogrel resistance?

Circulation 2009 Jun;119(21):2854-7

Institut de Cardiologie, INSERM, Université Paris, Hôpital Pitié-Salpêtrière, France.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.108.857722DOI Listing
June 2009